Non-independent quantum bumps in Limulus ventral nerve photoreceptors--a new insight in the light transduction mechanism.

Abstract:

:Single photon-induced transient currents, called quantum bumps were stimulated by short flashes in dark-adapted ventral nerve photoreceptors of Limulus. Flash intensities were set to activate 3 or more bumps. In most cases, current bumps were activated with a constant rate. The frequency of bump occurrence was between 9 and 17 Hz. Results show that consecutive bumps are not independent and that some of them are not activated by a photon. The periodic bump activation indicates a molecular mechanism which quantifies the transmitter release not only by a light quantum, but also by a late phase of the transduction cascade. A model is proposed, in which Ca2+ ions released from intracellular stores transiently block the further Ca2+ release by inositol trisphosphate in an all-or-none manner.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Nagy K

doi

10.1016/0304-3940(92)90725-m

keywords:

subject

Has Abstract

pub_date

1992-09-14 00:00:00

pages

99-102

issue

1-2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(92)90725-M

journal_volume

144

pub_type

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