Abstract:
:Single photon-induced transient currents, called quantum bumps were stimulated by short flashes in dark-adapted ventral nerve photoreceptors of Limulus. Flash intensities were set to activate 3 or more bumps. In most cases, current bumps were activated with a constant rate. The frequency of bump occurrence was between 9 and 17 Hz. Results show that consecutive bumps are not independent and that some of them are not activated by a photon. The periodic bump activation indicates a molecular mechanism which quantifies the transmitter release not only by a light quantum, but also by a late phase of the transduction cascade. A model is proposed, in which Ca2+ ions released from intracellular stores transiently block the further Ca2+ release by inositol trisphosphate in an all-or-none manner.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Nagy Kdoi
10.1016/0304-3940(92)90725-mkeywords:
subject
Has Abstractpub_date
1992-09-14 00:00:00pages
99-102issue
1-2eissn
0304-3940issn
1872-7972pii
0304-3940(92)90725-Mjournal_volume
144pub_type
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