Abstract:
:The voltage dependency of the ON and the OFF components of transient amacrine cell responses was studied using two-electrode voltage-clamp and current-clamp techniques in the isolated retina of the carp. The two independent approaches gave similar data. When cells were voltage clamped near their resting potentials, both response components were associated with transient inward currents. Hyperpolarization increased response size (current or voltage) whilst depolarization decreased it. Response reversal, or a tendency for it, occurred at membrane potentials significantly more positive than the resting level with some quantitative variability. These data support the view that the ON-OFF depolarizations represent basically excitatory postsynaptic potentials and that the transience of the responses cannot mainly be due to any voltage-dependent conductance.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Djamgoz MB,Low JC,Saito T,Toyoda JI,Yamada Mdoi
10.1016/0304-3940(96)12900-1subject
Has Abstractpub_date
1996-08-23 00:00:00pages
127-30issue
2-3eissn
0304-3940issn
1872-7972pii
0304-3940(96)12900-1journal_volume
214pub_type
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