Dopamine β Hydroxylase (DBH) is a potential modifier gene associated with Parkinson's disease in Eastern India.

abstract：:The orexinergic neurons, localized in the perifornical hypothalamic area (PeF), are active during waking and quiet during non-rapid eye movement (non-REM) and REM sleep. Orexins promote arousal and suppress non-REM and REM sleep. Although in vitro studies suggest that PeF-orexinergic neurons are under glutamatergic in...

journal_title：Neuroscience letters

authors： Alam MA,Mallick BN

更新日期：2008-07-18 00:00:00

abstract：:Since greater attention has been paid to the direct link of genetic variation to cognition and memory performance, apolipoprotein E (ApoE) and brain-derived neurotrophic factor (BDNF) have been the two most frequently studied genes. To investigate the effect of BDNF and ApoE polymorphisms on the cognitive profile of m...

journal_title：Neuroscience letters

authors： Nacmias B,Piccini C,Bagnoli S,Tedde A,Cellini E,Bracco L,Sorbi S

更新日期：2004-09-09 00:00:00

abstract：:Delta9-THC and synthetic cannabinoids produce memory impairment in humans as well as in laboratory animals. The high concentration of cannabinoid CB1 receptors and the presence of endocannabinoids in the hippocampus suggest that a cannabinoid neurochemical system may play a role in learning and memory processes. Thus,...

journal_title：Neuroscience letters

authors： Takahashi RN,Pamplona FA,Fernandes MS

更新日期：2005-06-03 00:00:00

abstract：:To investigate changes in regional cerebral blood flow (rCBF) under the prone condition with and without light massage on the back, we measured rCBF quantitatively in healthy human subjects using positron emission tomography with H(2)15O. Biochemical tests showed that the light massage (palm-pressure) reduced levels o...

journal_title：Neuroscience letters

authors： Ouchi Y,Kanno T,Okada H,Yoshikawa E,Shinke T,Nagasawa S,Minoda K,Doi H

更新日期：2006-10-23 00:00:00

abstract：:RGS (regulators of G protein signaling) proteins negatively regulate the alpha subunit of G proteins by accelerating their intrinsic GTPase activity. In a previous work, we reported the cloning of a cDNA encoding for a new RGS protein, RET-RGS. We showed that it is specifically expressed in the retina, notably by phot...

journal_title：Neuroscience letters

authors： Faurobert E,Scotti A,Hurley JB,Chabre M

更新日期：1999-07-02 00:00:00

abstract：:Somatostatin and several analogues were injected into rat striatum and their effects on dopamine, serotonin and their metabolites were examined at 1 h. Somatostatin induced a dose-dependent increase in dopamine turnover in the ipsilateral striatum accompanied by a reduction in turnover on the contralateral side. There...

journal_title：Neuroscience letters

authors： Beal MF,Martin JB

更新日期：1984-02-24 00:00:00

abstract：:Previous studies using various excitatory amino acid antagonists have shown that synaptic transmission between the auditory nerve and the cochlear nucleus of chickens (nuc. magnocellularis; NM) is mediated by non-N-methyl-D-aspartate (non-NMDA) receptors. In the present study we have attempted to define the subclass o...

journal_title：Neuroscience letters

authors： Nemeth EF,Jackson H,Parks TN

更新日期：1985-09-06 00:00:00

abstract：:The absence of smooth endoplasmic reticulum (SER) in the dendritic spine of Purkinje cells was found in dilute-lethal (dl) mouse cerebella as detected by immunohistochemistry using anti-inositol 1,4,5-triphosphate receptor antibody and electron microscopy. Since SER in the spine has been suggested to play a crucial ro...

journal_title：Neuroscience letters

authors： Takagishi Y,Oda S,Hayasaka S,Dekker-Ohno K,Shikata T,Inouye M,Yamamura H

更新日期：1996-09-13 00:00:00

abstract：:Chronic exposure of cultured canine cerebral vascular smooth muscle cells to ethanol (10-400 mM) for 1-5 days resulted in significant concentration-dependent elevation in resting intracellular free calcium ([Ca2+]i) levels. Preincubation of these cultured vascular cells with inhibitors of protein kinase C (PKC), staur...

journal_title：Neuroscience letters

authors： Zheng T,Li W,Zhang A,Altura BT,Altura BM

更新日期：1998-01-30 00:00:00

abstract：:Incorporation of ubiquitin and ubiquitin-related proteins including p62 into neuronal intranuclear inclusions (NIIs) has been reported in a variety of neurodegenerative diseases. However, involvement of autophagy-specific proteins (NBR1 and LC3) in NIIs has not been mentioned. We immunohistochemically examined the bra...

journal_title：Neuroscience letters

authors： Mori F,Tanji K,Odagiri S,Toyoshima Y,Yoshida M,Kakita A,Takahashi H,Wakabayashi K

更新日期：2012-08-01 00:00:00

abstract：:The relation between phantom limb pain (PLP) and the movement representation of a phantom limb remains controversial in several areas of neurorehabilitation, although there are a few studies in which the representation of phantom limb movement was precisely evaluated. We evaluated the structured movement representatio...

journal_title：Neuroscience letters

authors： Osumi M,Sumitani M,Wake N,Sano Y,Ichinose A,Kumagaya S,Kuniyoshi Y,Morioka S

更新日期：2015-09-25 00:00:00

abstract：:The present study investigated the changes in the expression of regulators of G-protein-coupled signaling proteins RGS2, 7 and 8 in gerbil hippocampus to better understand alterations of G-protein-coupled receptors signaling after cerebral ischemia. In situ hybridization revealed a transient, robust early increase in ...

journal_title：Neuroscience letters

authors： Shelat PB,Coulibaly AP,Wang Q,Sun AY,Sun GY,Simonyi A

更新日期：2006-07-31 00:00:00

abstract：:A dimeric form of acetylcholinesterase from the electric organ of Torpedo californica was solubilized by phosphatidylinositol-specific phospholipase C from Staphylococcus aureus. The solubilized enzyme had a sedimentation coefficient of 7.3S which was not modified by detergents. The high salt-soluble asymmetric forms ...

journal_title：Neuroscience letters

authors： Futerman AH,Low MG,Silman I

更新日期：1983-09-19 00:00:00

abstract：:'Clipsin' and other peptide bond hydrolase activities that appear to be integral membrane proteins, including two implicated in the formation of the histological hallmarks of Alzheimer's disease, were assayed in the frontal and parietal cortex from a large (n = 45) series of postmortem human brains. Tissues were extra...

journal_title：Neuroscience letters

authors： Stratmann GC,Webster MT,Francis PT,Procter AW,Bowen DM

更新日期：1992-08-31 00:00:00

abstract：:Corticokinematic coherence (CKC), i.e., coherence calculated between MEG and an accelerometer signal, recording movement kinematics, can be used for functional mapping of the sensorimotor cortex. Cortical sources of CKC, induced by both voluntary and passive movements, localize at the proximity of sensorimotor cortex....

journal_title：Neuroscience letters

authors： Airaksinen K,Lehti T,Nurminen J,Luoma J,Helle L,Taulu S,Pekkonen E,Mäkelä JP

更新日期：2015-08-18 00:00:00

abstract：:The hippocampal formation plays a critical role in episodic memory formation and spatial navigation. Within the hippocampus, the subiculum is considered to be a hub connecting the hippocampal formation to the remainder of the brain. There are functional differences between the dorsal and ventral part of subiculum, whi...

journal_title：Neuroscience letters

authors： Tang H,Wu GS,Xie J,He X,Deng K,Wang H,Xu F,Luo HR

更新日期：2016-08-26 00:00:00

abstract：:Vertical arm pointing movements in two directions (upwards and downwards), imposing two different loads (unload and 0.5 kg) and speeds (normal and fast) have been studied in six subjects. Movements were recorded using an optoelectronic system. Data analysis concentrated upon finger-tip kinematics. Significant effects ...

journal_title：Neuroscience letters

authors： Papaxanthis C,Pozzo T,Stapley P

更新日期：1998-09-04 00:00:00

abstract：:To assess the neurotoxic properties of the glutamate agonist quisqualic acid (QA) in immature brain, we injected this compound (100 nmol QA/1 microliter) directly into the striatum of 7-day-old rats. QA produced neuronal necrosis and glial infiltration in 14 pups and reduced the size of the striatum and hippocampus on...

journal_title：Neuroscience letters

authors： Silverstein FS,Chen R,Johnston MV

更新日期：1986-10-30 00:00:00

abstract：:The alternation of sounds in the left and right ears induces motion perception of a static visual stimulus (SIVM: Sound-Induced Visual Motion). In this case, binaural cues were of considerable benefit in perceiving locations and movements of the sounds. The present study investigated how a spectral cue - another impor...

journal_title：Neuroscience letters

authors： Teramoto W,Manaka Y,Hidaka S,Sugita Y,Miyauchi R,Sakamoto S,Gyoba J,Iwaya Y,Suzuki Y

更新日期：2010-08-02 00:00:00

abstract：:As noted in the aging literature, processing delays often occur in the central nervous system with increasing age, which is often attributable in part to demyelination. In addition, differential slowing between sensory systems has been shown to be most discrepant between visual (up to 20ms) and auditory systems (<5ms)...

journal_title：Neuroscience letters

authors： Stephen JM,Knoefel JE,Adair J,Hart B,Aine CJ

更新日期：2010-10-22 00:00:00

abstract：:Amyloid beta (Aβ) is the main component of the amyloid plaques that accumulate in the brains of Alzheimer patients. Here, we reported the protective role of Formononetin (Form) against Aβ25-35-induced neurotoxicity in HT22 cells. We found that Form significantly increased the viability of HT22 cells but decreased the ...

journal_title：Neuroscience letters

authors： Chen L,Ou S,Zhou L,Tang H,Xu J,Guo K

更新日期：2017-02-03 00:00:00

abstract：:This study reports the solubilization of the rat synaptic vesicle protein SV2A, the brain binding site for the antiepileptic drug levetiracetam (LEV), and its characterization. N-dodecyl-beta-D-maltoside (DDM) was the best detergent at achieving a high percentage of SV2A solubilization and at maintaining the binding c...

journal_title：Neuroscience letters

authors： Lambeng N,Grossmann M,Chatelain P,Fuks B

更新日期：2006-05-01 00:00:00

abstract：:The circadian modulation of occurrence of non-rapid-eye-movement sleep (NREM) was investigated in 37 volunteers under dim-light conditions after 24-h total sleep deprivation using a 26-h 10/20-min ultra-short sleep-wake schedule. The propensity of NREM showed rapid increase followed by gradual decrease during the subj...

journal_title：Neuroscience letters

authors： Tagaya H,Uchiyama M,Shibui K,Kim K,Suzuki H,Kamei Y,Okawa M

更新日期：2002-04-19 00:00:00

abstract：:Copulation was induced in pairs of Aplysia fasciata by adding to the environment a homogenate of the distal portion of the large hermaphroditic duct. Similar effects were not observed in response to an abdominal ganglion homogenate. The data suggest that the duct may secrete a pheromone initiating copulation in Aplysi...

journal_title：Neuroscience letters

authors： Susswein AJ,Benny M

更新日期：1985-09-06 00:00:00

abstract：:Focal brain lesions such as cortical dysplasia and glioneural tumors generate epileptic activity and thus may be synaptically connected with normal cortex. To test this hypothesis, we compared event-related potentials recorded directly from the medial temporal lobe (MTL) and a dysplastic lesion in eight patients with ...

journal_title：Neuroscience letters

authors： Kirschstein T,Fernández G,Grunwald T,Pezer N,Urbach H,Blümcke I,Van Roost D,Lehnertz K,Elger CE

更新日期：2003-03-06 00:00:00

abstract：:The effect of the neuropeptide, substance P, on the transport of D-[(3)H]aspartate into rat striatal synaptosomes was studied. Almost 90% of the total transport of D-[(3)H]aspartate was sodium-dependent and the maximum rate (V(max)) of this transport was increased by 34% of control by 2.5 nM substance P (EC(50)=0.52 n...

journal_title：Neuroscience letters

authors： Healy J,Downes A,McBean GJ

更新日期：2000-08-25 00:00:00

abstract：:The death of neurons after brain ischaemia may be associated with activation of cyclin-dependent kinases (CDKs) and upregulation of cyclins, reflecting aberrant entry of neurons into the cell cycle. Little has been published on the expression of cell cycle proteins after brain ischaemia in man. Well-characterized anti...

journal_title：Neuroscience letters

authors： Love S

更新日期：2003-12-15 00:00:00

abstract：:A possible role of the human cerebellum in the generation of verbs corresponding to presented nouns has been suggested. Previous functional brain imaging studies have compared generation of verbs with the reading of nouns as a measure of verb generation. In the present fMRI study involving healthy human subjects, the ...

journal_title：Neuroscience letters

authors： Frings M,Dimitrova A,Schorn CF,Elles HG,Hein-Kropp C,Gizewski ER,Diener HC,Timmann D

更新日期：2006-11-27 00:00:00

abstract：:Carrier-mediated transport of small peptides and peptidomimetics offers the opportunity for a targeted drug delivery across cell membranes in the central nervous system (CNS). This process is mediated by the proton-coupled transporter PEPT2 which is expressed in glial and choroid plexus cells. In the present studies, ...

journal_title：Neuroscience letters

authors： Groneberg DA,Rubio-Aliaga I,Nickolaus M,Döring F,Fischer A,Daniel H

更新日期：2004-06-24 00:00:00

abstract：:The effect of the R(-) and S(+) isomers of 3,4-methylenedioxyamphetamine (MDA) and its N-methyl analog 3,4-methylenedioxymethamphetamine (MDMA) on [3H]inositol monophosphate accumulation was studied in cells expressing either 5-HT2A or 5-HT2C receptors. The isomers of MDA produced a concentration dependent increase in...

journal_title：Neuroscience letters

authors： Nash JF,Roth BL,Brodkin JD,Nichols DE,Gudelsky GA

更新日期：1994-08-15 00:00:00