Stimulation of synaptosomal D-[(3)H]aspartate transport by substance P in rat brain.

abstract：:Attention deficit hyperactivity disorder (ADHD) is a developmental disorder characterized by inattentiveness, motor hyperactivity and impulsivity. According to neuroimaging data, the neural substrate underlying ADHD seems to involve fronto-striatal circuits and the cerebellum. However, there are important discrepancie...

journal_title：Neuroscience letters

authors： Carmona S,Vilarroya O,Bielsa A,Trèmols V,Soliva JC,Rovira M,Tomàs J,Raheb C,Gispert JD,Batlle S,Bulbena A

更新日期：2005-12-02 00:00:00

abstract：:Using the dipole-tracing method, the source generators of N18, P22 and P40 of the somatosensory evoked potential (SEP) were estimated as the equivalent dipole. After voluntary action of the thumb flexion, no changes were observed in N18 or P40, but the amplitude of P22 was suppressed. The after-effects of intention ac...

journal_title：Neuroscience letters

authors： Homma S,Nakajima Y,Musha T,He B,Okamoto Y

更新日期：1988-06-07 00:00:00

abstract：:Parkinson's disease (PD) etiology has been attributed both to genetic and environmental factors, although the exact mechanisms of its pathogenesis remains elusive. We investigated Brazilian early-onset PD (EOPD) patients with PINK1 polymorphisms (SNPs) in order to find possible correlations between SNPs, environmental...

journal_title：Neuroscience letters

authors： Godeiro C Jr,Aguiar PM,Felício AC,Barsottini OG,Silva SM,Borges V,Andrade LA,Ferraz HB

更新日期：2010-01-18 00:00:00

abstract：:This study investigated the neuroprotective effects of COG1410, an apoliporotein E (apoE)-derived mimic peptide, against early brain injury (EBI) after subarachnoid hemorrhage (SAH). SAH was induced in C57BL/6J mice (n=68) by endovascular perforation. Mice received intravenous injection of COG1410 (2mg/kg) or equal vo...

journal_title：Neuroscience letters

authors： Wu Y,Pang J,Peng J,Cao F,Vitek MP,Li F,Jiang Y,Sun X

更新日期：2016-08-03 00:00:00

abstract：:Fibroblasts from Alzheimer's disease (AD) patients displayed decreased cytochrome c oxidase (complex IV) activity (P < 0.05). The basal oxygen consumption rate (QO2) and the response to an uncoupler of oxidative phosphorylation did not differ between AD and control fibroblasts. The QO2 of AD fibroblasts was more susce...

journal_title：Neuroscience letters

authors： Curti D,Rognoni F,Gasparini L,Cattaneo A,Paolillo M,Racchi M,Zani L,Bianchetti A,Trabucchi M,Bergamaschi S,Govoni S

更新日期：1997-10-24 00:00:00

abstract：:Cerebrospinal fluid (CSF) was obtained from donor rats either during the dark or during the light period of their diurnal cycle, and infused into the lateral ventricle of recipient rats. Infusing recipient rats during their dark period with CSF from light-exposed donors reduced the motor activity, whereas, conversely,...

journal_title：Neuroscience letters

authors： Sachs J,Ungar J,Waser PG,Borbély AA

更新日期：1976-04-01 00:00:00

abstract：:Morphine and other opioids have direct analgesic actions in the spinal cord and chronic spinal administration of opioid agonists is used clinically in patients suffering from severe, chronic pain. Neuropathic pain resulting from peripheral nerve injury is often less sensitive to opioid therapy than other forms of chro...

journal_title：Neuroscience letters

authors： Stone LS,Vulchanova L,Riedl MS,Williams FG,Wilcox GL,Elde R

更新日期：2004-05-06 00:00:00

abstract：:Recent research in social neuroscience proposes a link between mirror neuron system (MNS) and social cognition. The MNS has been proposed to be the neural mechanism underlying action recognition and intention understanding and more broadly social cognition. Pre-motor MNS has been suggested to modulate the motor cortex...

journal_title：Neuroscience letters

authors： Puzzo I,Cooper NR,Vetter P,Russo R,Fitzgerald PB

更新日期：2009-12-25 00:00:00

abstract：:Rabbit retinal Müller cells were isolated by means of papaine and mechanical dissociation. These cells were shown to have a well preserved morphology and to preserve viability for many hours. Intense wheat germ agglutinin binding occurs on the photoreceptor side of Müller cells, especially in the microvillous region. ...

journal_title：Neuroscience letters

authors： Reichenbach A,Dettmer D,Brückner G,Neumann M,Birkenmeyer G

更新日期：1985-03-22 00:00:00

abstract：:Local warming or cooling of the preoptic and anterior hypothalamus (PO/AH) areas evokes various thermoregulatory responses in mammals. We have hypothesized that warm- and cold-sensitive neurons recorded in the PO/AH are multiple thermostats that regulate the core temperature against heat and cold, respectively. Howeve...

journal_title：Neuroscience letters

authors： Abe J,Okazawa M,Adachi R,Matsumura K,Kobayashi S

更新日期：2003-05-15 00:00:00

abstract：:The etiology of schizophrenia is unknown, but the pathogenetic process involves organic changes in brain tissue, which may alter the composition of cerebrospinal fluid (CSF). For the present study, CSF was obtained by lumbar puncture from 22 schizophrenic patients and 38 control patients. We have used scanning electro...

journal_title：Neuroscience letters

authors： Wetterberg L,Nybom R,Bratlid T,Fladby T,Olsson B,Wigzell H

更新日期：2002-08-23 00:00:00

abstract：:Precursor cells have been shown to be affected by oxidative stress, in vivo and vitro, but little is known about the expression of antioxidant mechanisms in neuronal/glial differentiation. We have characterized the expression of Cu/Zn superoxide dismutase (Cu/Zn SOD), one of the main antioxidant proteins involved in t...

journal_title：Neuroscience letters

authors： Faiz M,Acarin L,Peluffo H,Villapol S,Castellano B,González B

更新日期：2006-06-19 00:00:00

abstract：:Day-night variations of gastrin releasing peptide (GRP) in the neuronal somal area of the SCN and the nearby region on the anterior hypothalamic area (AHA) where GRP fibers project, were examined by semiquantitative immunocytochemistry, and compared with those of vasoactive intestinal peptide (VIP). Both in the SCN an...

journal_title：Neuroscience letters

authors： Okamura H,Ibata Y

更新日期：1994-11-07 00:00:00

abstract：:We investigated the cortico-muscular coherence in a patient with posturally induced cortically originating negative myoclonus. We recorded simultaneously 50 channels EEG and EMG from quadriceps and biceps femoris muscles of the left upper leg. Three experimental conditions were investigated with the patient in a seate...

journal_title：Neuroscience letters

authors： Kristeva R,Popa T,Chakarov V,Hummel S

更新日期：2004-08-19 00:00:00

abstract：:The effect of partial isomerization of dietary alpha-linolenic acid on the monoaminergic neurotransmitters in piglets was studied. After feeding the animals for 14 days with diets containing or not trans alpha-linolenic acid, neurotransmitters related to the monoaminergic function were quantified in the frontal cortex...

journal_title：Neuroscience letters

authors： Acar N,Chardigny JM,Berdeaux O,Almanza S,Sébédio JL

更新日期：2002-10-18 00:00:00

abstract：:People with Down syndrome develop Alzheimer's disease with an early age of onset. Plasma amyloid beta (Abeta) levels were measured in individuals with Down syndrome who were over the age of 40. No associations between age and Abeta1-40 and Abeta1-42 concentrations were found and nor were Abeta1-40 and Abeta1-42 levels...

journal_title：Neuroscience letters

authors： Jones EL,Hanney M,Francis PT,Ballard CG

更新日期：2009-02-20 00:00:00

abstract：:The effects of gonadal steroids on serotonin (5-HT) synthesis and metabolism in the early developing brain were investigated. Seven-day-old (7 days post-hatch) tilapia, Oreochromis mossambicus were continuously treated with 17beta-estradiol (E2), methyltestosterone (MT) and para-chlorophenylalanine (p-PCA) up to the a...

journal_title：Neuroscience letters

authors： Tsai CL,Wang LH

更新日期：1999-04-02 00:00:00

abstract：:Nicotine is known to stimulate energy expenditure, although the precise mechanism is unclear. To clarify the involvement of corticotropin-releasing factor (CRF) in the mechanism by which nicotine increases energy expenditure, the effect of intraperitoneal injection of nicotine (0.1 or 0.5mg/kg) on the release of norad...

journal_title：Neuroscience letters

authors： Mano-Otagiri A,Iwasaki-Sekino A,Ohata H,Arai K,Shibasaki T

更新日期：2009-05-08 00:00:00

abstract：:The expression of metabotropic glutamate receptor 8 (mGluR8) was studied in the rat hippocampus after pilocarpine-induced status epilepticus (APISE) by light immunohistochemistry and immunoelectron microscopy. At 1 day APISE, mGluR8 immunoreactivity was up-regulated in the entire molecular layer of the dentate gyrus. ...

journal_title：Neuroscience letters

authors： Tang FR,Lee WL,Yang J,Sim MK,Ling EA

更新日期：2001-03-16 00:00:00

abstract：:Differential performance over a wide range of possible postural coordination modes was investigated using 16 ankle-hip relative phase patterns from 0 degrees to 337.5 degrees. Participants were instructed to produce each coordination mode with and without real time visual feedback. Feedback consisted of a Lissajous fi...

journal_title：Neuroscience letters

authors： Faugloire E,Bardy BG,Merhi O,Stoffregen TA

更新日期：2005-02-10 00:00:00

abstract：:Beta,beta'-Iminodipropionitrile (IDPN) is known to produce a massive accumulation of neurofilaments in the proximal portion of axons of spinal anterior horn cells. The spinal cords of 20 Wistar rats treated with IDPN were examined immunohistochemically with a monoclonal antibody against heparan sulfate (HepSS-1). Virt...

journal_title：Neuroscience letters

authors： Wada M,Kato T,Kurita K,Shikama Y,Toyoshima I,Sasaki H

更新日期：1995-12-29 00:00:00

abstract：:During early postnatal phase, the environment deeply affects developmental trajectories through epigenetic mechanisms that control the levels of key molecules for brain function, such as neurotrophins. Indeed, it has been shown that adverse early experiences induce epigenetic modifications leading to decreased brain d...

journal_title：Neuroscience letters

authors： Branchi I,Karpova NN,D'Andrea I,Castrén E,Alleva E

更新日期：2011-05-20 00:00:00

abstract：:The olfactory system plays an important role in both animal and human anxiety reactions. However, results on olfactory performance during the course of clinical anxiety disorders remain scarce. Therefore, we conducted an exploratory pilot study in 17 patients currently diagnosed with an anxiety disorder. Patients part...

journal_title：Neuroscience letters

authors： Clepce M,Reich K,Gossler A,Kornhuber J,Thuerauf N

更新日期：2012-03-05 00:00:00

abstract：:The autoradiographic [14C]2-deoxyglucose (2-DG) method was used to map the descending effects of midbrain reticular stimulation on the rat cervical spinal cord. The stimulation evoked consistently a defensive 'freezing' reaction as well as a large and highly localized increase in 2-DG uptake in the substantia gelatino...

journal_title：Neuroscience letters

authors： Gonzalez-Lima F

更新日期：1986-04-24 00:00:00

abstract：:Although synaptically released, vesicular Zn(2+) has been proposed to play a neuromodulatory or neuronal signaling role at the mossy fiber-CA3 synapse, Zn(2+) release remains controversial, especially when detected using fluorescent imaging. In the present study, we investigated synaptically released Zn(2+) at the mos...

journal_title：Neuroscience letters

authors： Bastian C,Li YV

更新日期：2007-05-29 00:00:00

abstract：:The density of hippocampal adenosine A1 receptors was measured in autopsy samples of six patients with dementia with either Alzheimer (three) or sclerosis type pathology (three) in hippocampus and six control patients. Kinetic parameters (Bmax and KD) were determined by means of quantitative autoradiography using [3H]...

journal_title：Neuroscience letters

authors： Deckert J,Abel F,Künig G,Hartmann J,Senitz D,Maier H,Ransmayr G,Riederer P

更新日期：1998-03-06 00:00:00

abstract：:NMDA and non-NMDA receptor-mediated components of excitatory post-synaptic current (EPSC) were studied by in situ whole-cell voltage-clamp recordings in the CA1 field of rat hippocampus. We found that the amplitudes ratio of the NMDA to the non-NMDA components can be strongly increased by blocking A1 adenosine recepto...

journal_title：Neuroscience letters

authors： Klishin A,Lozovaya N,Krishtal O

更新日期：1994-09-26 00:00:00

abstract：:Suicide is a major contributor to the morbidity and mortality of schizophrenia, accounting for approximately 10% of deaths in these patients. Genetic factors have been reported to modulate the risk for suicide, although the precise mechanism and magnitude of the genetic contribution are unknown. Further, suicide attem...

journal_title：Neuroscience letters

authors： Souza RP,De Luca V,Manchia M,Kennedy JL

更新日期：2011-02-11 00:00:00

abstract：:Adolescence is characterized by a relative immaturity of the prefrontal cortex and associated cognitive control functions, which is hypothesized to be a major contributing factor to high-risk behaviors. However, little is known about the role of genetic and environmental factors in frontal brain development during ado...

journal_title：Neuroscience letters

authors： Anokhin AP,Golosheykin S,Grant JD,Heath AC

更新日期：2010-03-19 00:00:00

abstract：:Because reelin and prestin genes are located close together on mouse chromosome 5, reelin homozygous mutant mice were compared with littermate controls. Experiments were designed to determine if the deletion in the reeler mouse affects the coding and/or regulatory regions for the expression of prestin, the outer hair ...

journal_title：Neuroscience letters

authors： Zheng J,Richter CP,Cheatham MA

更新日期：2003-08-14 00:00:00