Modification of the monoaminergic neurotransmitters in frontal cortex and hippocampus by dietary trans alpha-linolenic acid in piglets.

abstract：:Mutations in the glucocerebrosidase gene (GBA) have recently been associated with an increased risk of Parkinson disease (PD). GBA mutations have been observed to be particularly prevalent in the Ashkenazi Jewish population. Interestingly, this population also has a high incidence of the Lrrk2 p.G2019S mutation which ...

journal_title：Neuroscience letters

authors： Nishioka K,Vilariño-Güell C,Cobb SA,Kachergus JM,Ross OA,Wider C,Gibson RA,Hentati F,Farrer MJ

更新日期：2010-06-21 00:00:00

abstract：:A brief hammer tap applied passively (by the experimenter) to the forearm elicits a short-latency reflex response in the forearm flexors and extensors. When the same tap is performed actively (by the subject) using the opposite forearm, the reflex response is preceded by a short-lasting anticipatory reduction in the m...

journal_title：Neuroscience letters

authors： Struppler A,Gerilovsky L,Jakob C

更新日期：1993-09-03 00:00:00

abstract：:The neuromuscular junction (NMJ) is the vehicle for fast, reliable and robust communication between motor neuron and muscle. The unparalleled accessibility of this synapse to morphological, electrophysiological and genetic analysis has yielded an in depth understanding of many molecular components mediating its format...

journal_title：Neuroscience letters

authors： Fish LA,Fallon JR

更新日期：2020-07-13 00:00:00

abstract：:Sapogenins from Anemarrhenae asphodeloides was reported to improve the learning and memory abilities. In this study, we investigated the effect of Timosaponin B-II(TB-II), a purified extract from A. asphodeloidesb on rat vascular dementia (VD) produced by transient (2h) middle cerebral artery occlusion. The learning a...

journal_title：Neuroscience letters

authors： Li TJ,Qiu Y,Yang PY,Rui YC,Chen WS

更新日期：2007-06-27 00:00:00

abstract：:Dopaminergic brain systems have been implicated to play a major role in drug reward, thus making genes involved in these circuits plausible candidates for susceptibility to substance use disorders. The cocaine- and amphetamine-regulated transcript peptide (CARTPT) is involved in reward and feeding behavior and has fun...

journal_title：Neuroscience letters

authors： Lohoff FW,Bloch PJ,Weller AE,Nall AH,Doyle GA,Buono RJ,Ferraro TN,Kampman KM,Pettinati HM,Dackis CA,Oslin DW,O'Brien CP,Berrettini WH

更新日期：2008-08-08 00:00:00

abstract：:Several constituents of chromaffin granules were quantitatively determined in noradrenaline and adrenaline cells purified from bovine adrenal medulla. As far as secretory peptides are concerned noradrenaline granules contained slightly more secretogranin II, but much less chromogranin A than adrenaline granules. This ...

journal_title：Neuroscience letters

authors： Weiss C,Cahill AL,Laslop A,Fischer-Colbrie R,Perlman RL,Winkler H

更新日期：1996-06-14 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) has been proposed as a key regulator and mediator of long-term synaptic modifications related to learning and memory maintenance. Our previous studies show that application of high-frequency stimulation (HFS) sufficient to elicit LTP at the dentate gyrus (DG)-CA3 pathway produc...

journal_title：Neuroscience letters

authors： Gómez-Palacio-Schjetnan A,Escobar ML

更新日期：2008-11-07 00:00:00

abstract：:We reported previously that administration of 1-oleoyl-2-docosahexaenoyl-sn-glycero-3-phosphorylcholine (ODHPC), a kind of phosphatidylcholine, enhanced discriminatory shock avoidance learning in rats. Since long-term potentiation (LTP) of the hippocampus has been suggested to be a physiological substrate of some form...

journal_title：Neuroscience letters

authors： Izaki Y,Hashimoto M,Arita J

更新日期：1999-01-29 00:00:00

abstract：:Anterior pharynx-defective 1 (Aph-1) is a multi-spanning membrane protein and an integral component of the high molecular weight gamma-secretase complex that also contains presenilin, nicastrin, and Pen-2. In order to clarify the existence of an endogenous fragment of Aph-1 and dissect the localization and processing ...

journal_title：Neuroscience letters

authors： Sanjo N,Katayama T,Hasegawa H,Jin H,Duthie M,Mount HT,Mizusawa H,St George-Hyslop P,Fraser PE

更新日期：2010-10-08 00:00:00

abstract：:Inflammation is an important contributor to the development of Alzheimer's disease (AD). Anti-inflammatory medication may offer promising treatment for AD. Hydroxy-safflor yellow A (HSYA), a chemical component of the safflower yellow pigments, has been reported to exert potent immunosuppressive effects. This study exa...

journal_title：Neuroscience letters

authors： Zhang Z,Wu Z,Zhu X,Hui X,Pan J,Xu Y

更新日期：2014-03-06 00:00:00

abstract：:Vascular endothelial growth factor (VEGF) regulates neurogenesis. The present study investigated the direct effect of VEGF on the enhancement of proliferation and differentiation of the adult mouse subventricular zone (SVZ) neural progenitors in vitro. A high dose (500 ng/ml) of VEGF significantly downregulated endoge...

journal_title：Neuroscience letters

authors： Meng H,Zhang Z,Zhang R,Liu X,Wang L,Robin AM,Chopp M

更新日期：2006-01-30 00:00:00

abstract：:Temporal patterns of inflammatory cytokine levels reflect the immune-inflammatory role in pathogenic mechanisms of SOD1 animal model of Amyotrophic Lateral Sclerosis (ALS) and these cytokines have important roles in both toxic and protective functions depending on the stage of disease progression in ALS patients. Eryt...

journal_title：Neuroscience letters

authors： Noh MY,Cho KA,Kim H,Kim SM,Kim SH

更新日期：2014-06-27 00:00:00

abstract：:The inferior alveolar nerves (IAN) of young male Wistar rats (b.wt. greater than or equal to 200 g) were transected unilaterally, slightly proximal to the mandibular foramen under anesthesia with chloral hydrate (0.4 g/kg, i.p.). After various postoperative periods of time, the animals received horseradish peroxidase ...

journal_title：Neuroscience letters

authors： Takemura M,Sugimoto T,Wakisaka S,Akai M

更新日期：1990-01-01 00:00:00

abstract：:The neuroprotective activity of riluzole has been studied on N-methyl-D-aspartate (NMDA)- or veratridine-induced toxicity in immature rat hippocampal slices. Neurodegeneration was assessed by the measurement of LDH release and histology. Veratridine-induced LDH release can be inhibited by 100 microM riluzole (-90% and...

journal_title：Neuroscience letters

authors： Malgouris C,Daniel M,Doble A

更新日期：1994-08-15 00:00:00

abstract：:In brainstem slices of guinea pigs perfused with artificial cerebro-spinal fluid (ACSF), the discharge of all the spontaneously active neurons of the medial vestibular nucleus (MVN) is regular. It has been reported that prolonged exposure to a low Ca(2+) medium could induce these neurons to fire bursts of spikes. In t...

journal_title：Neuroscience letters

authors： Ris L,Godaux E

更新日期：2001-01-12 00:00:00

abstract：:Previously published data have indicated that in the rat, unlike other species examined, the kidney is not supplied by sensory nerves containing substance P (SP). As part of a study of reflex control of renal function in the rat, we have now reassessed this situation. Many fine, varicose, SP-immunoreactive nerve fiber...

journal_title：Neuroscience letters

authors： Ferguson M,Bell C

更新日期：1985-09-30 00:00:00

abstract：:Two types of cone horizontal cells were identified morphologically in the retina of a trichromatic fish by fluorescent labelling with Lucifer Yellow and confocal laser scanning microscopy. H1 cells are located adjacent to the outer plexiform layer, have large somata, small dendritic fields, and contact all cone types....

journal_title：Neuroscience letters

authors： Braun SC,Kröger RH,Wagner HJ

更新日期：1997-10-17 00:00:00

abstract：:Regeneration of reduced nicotinamide adenine dinucleotide phosphate (NADPH) is essential for the activity of glutathione redox cycling during cellular peroxide detoxification. In order to test for a function of astroglial glycogen to serve as endogenous precursor for glucose-6-phosphate, the substrate for the regenera...

journal_title：Neuroscience letters

authors： Rahman B,Kussmaul L,Hamprecht B,Dringen R

更新日期：2000-09-01 00:00:00

abstract：:Evidence suggests that high peripheral beta-amyloid (Abeta)(1-40) levels and low ratios of Abeta(1-42)/Abeta(1-40) are associated with increased risk for Alzheimer's disease (AD). In this cross-sectional design, serum and plasma samples from 67 AD patients and 146 controls (similar in age and gender) were evaluated us...

journal_title：Neuroscience letters

authors： Abdullah L,Paris D,Luis C,Quadros A,Parrish J,Valdes L,Keegan AP,Mathura V,Crawford F,Mullan M

更新日期：2007-11-27 00:00:00

abstract：:Effects of the 1-methyl-4-phenylpyridinium ion (MPP+) on DOPA formation and phosphorylation of tyrosine hydroxylase (TH) of rat pheochromocytoma PC12h cells were examined after the cells were cultured with MPP+. DOPA formed from endogenous tyrosine in PC12h cells after a 3-day culture with 100 microM MPP+ was decrease...

journal_title：Neuroscience letters

authors： Kiuchi K,Hagiwara M,Hidaka H,Nagatsu T

更新日期：1988-06-29 00:00:00

abstract：:Effective treatments to improve survivability following exposure to the nerve agent soman have been established and are currently available. Unfortunately, electrographic brain seizures, neuroinflammation and brain cell death are still a potential problem even with treatment. In the present study we have characterized...

journal_title：Neuroscience letters

authors： Williams AJ,Berti R,Yao C,Price RA,Velarde LC,Koplovitz I,Schultz SM,Tortella FC,Dave JR

更新日期：2003-10-09 00:00:00

abstract：:The melanocortin receptor type 2 (MC2R or adrenocorticotropic hormone, ACTH receptor) gene (MC2R) encodes a protein involved in regulation of adrenal cortisol secretion, important in the physiological response to stressors. A variant of MC2R, -179A>G, results in reduction of promoter activity and less adrenal action. ...

journal_title：Neuroscience letters

authors： Proudnikov D,Hamon S,Ott J,Kreek MJ

更新日期：2008-04-25 00:00:00

abstract：:A three-dimensional (3D) clinostat is a device for generating multidirectional G force, resulting in an environment with an average of 10(-3)G. We cultured human malignant glioma cell lines in a 3D-clinostat (CL group) and examined the growth properties and chemosensitivity of the cells compared to cells cultured unde...

journal_title：Neuroscience letters

authors： Takeda M,Magaki T,Okazaki T,Kawahara Y,Manabe T,Yuge L,Kurisu K

更新日期：2009-09-29 00:00:00

abstract：:The present study aimed to validate a pictorial rating scale to evaluate the child's ability to produce grip forces. Thirty-seven children aged 3 to 6 years participated as subjects in this investigation. We used a tailor-made pictorial scale and a hand grip strength meter, as well as a Piaget's clinical interview aim...

journal_title：Neuroscience letters

authors： Defrasne Ait-Said E,Groslambert A,Courty D

更新日期：2007-06-13 00:00:00

abstract：:The effects of acute treatment with 1,2,3,4-tetrahydro-9-aminoacridine (THA), a 4-aminopyridine derivative clinically effective in Alzheimer's disease, on beta-adrenoceptor-linked cyclic AMP accumulation have been investigated in cortical and hippocampal structures of young and middle-aged rats. In a first series of e...

journal_title：Neuroscience letters

authors： Dierssen M,Màrmol F,Vivas NM,Clos MV,Gascón S,Badia A

更新日期：1991-10-28 00:00:00

abstract：:The effect of 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX), a specific non-N-methyl-D-aspartate (non-NMDA) receptor antagonist, on NMDA-independent epileptiform activity induced by Mg2(+)-free medium was studied in rat basolateral amygdala (BLA) neurons using intracellular recording techniques. Twenty to 30 min after s...

journal_title：Neuroscience letters

authors： Gean PW

更新日期：1990-10-30 00:00:00

abstract：:The present event-related potential (ERP) study was conducted to investigate the P3 component in response to love-related stimuli while controlling for task-related factors, and to dissociate the influences of both love-related and task-related attention on the P3 amplitude. In an oddball paradigm, photographs of belo...

journal_title：Neuroscience letters

authors： Langeslag SJ,Franken IH,Van Strien JW

更新日期：2008-02-06 00:00:00

abstract：:Our previous study demonstrated that successive electroacupuncture (EA) at ST36 acupoint reduces IgE production in BALB/c mice immunized with 2,4-dinitrophenylated keyhole limpet protein (DNP-KLH) by suppression of the Th2 cell lineage development. Here, we report that pretreatment of phentolamine (alpha-adrenoceptor ...

journal_title：Neuroscience letters

authors： Lee Y,Kim SK,Kim Y,Lee H,Shin MK,Hong MC,Min BI,Bae H

更新日期：2007-08-16 00:00:00

abstract：:Somatosensory amplification refers to the tendency to experience benign and ambiguous somatic sensation as intense, noxious, and disturbing. The construct is helpful in assessing the perceptual style of a variety of somatizing conditions, but there is no human study clarifying the effects of neurological function on s...

journal_title：Neuroscience letters

authors： Nakao M,Barsky AJ,Nishikitani M,Yano E,Murata K

更新日期：2007-03-26 00:00:00

abstract：:Although the coadministration of lidocaine with propranolol interferes with the metabolic profile (pharmacokinetics), its pharmacodynamics is still unclear. In this report, we investigate whether propranolol can potentiate the effect of lidocaine. Rats received spinal anesthesia with lidocaine co-injected with propran...

journal_title：Neuroscience letters

authors： Chen YW,Chu CC,Chen YC,Hung CH,Li YT,Wang JJ

更新日期：2011-09-26 00:00:00