In vivo BDNF modulation of adult functional and morphological synaptic plasticity at hippocampal mossy fibers.

abstract：:We looked for an interaction between etifoxine and the neurosteroid allopregnanolone at central gamma-aminobutyric acid (GABA(A)) receptors. Etifoxine (2 microM) did not affect the affinity of allopregnanolone (IC(50)=108 nM) for its site in preparations of Sprague-Dawley rat cerebral cortex membranes, as determined b...

journal_title：Neuroscience letters

authors： Verleye M,Schlichter R,Neliat G,Pansart Y,Gillardin JM

更新日期：2001-04-06 00:00:00

abstract：:Galanin- and bethanechol-activated whole cell currents were studied in dissociated mudpuppy parasympathetic neurons kept in 12.5 mM KCl. The bethanechol-induced current was reduced when generated during a galanin-induced current. The galanin and bethanechol currents reversed at -45 mV and exhibited inward rectificatio...

journal_title：Neuroscience letters

authors： Parsons RL,Merriam LA

更新日期：1992-06-08 00:00:00

abstract：:The retrofacial nucleus project bilaterally to the ventrolateral nucleus of the tractus solitarius (vlNTS) as revealed by means of retrograde transport of the fluorescent markers, Fast blue (FB) and Diamidino yellow (DY), in the cat. Some of the neurons of the retrofacial nucleus send axonal ramifications to both vlNT...

journal_title：Neuroscience letters

authors： Portillo F,Pásaro R

更新日期：1987-05-19 00:00:00

abstract：:Aquaporin-1 (AQP1) is a water channel expressed in the choroid plexus and participates in forming cerebrospinal fluid. Interestingly, reactive astrocytes also express AQP1 in the central nervous system under some pathological conditions. On the other hand, 3-nitropropionic acid (3NP) is a mitochondrial toxin that caus...

journal_title：Neuroscience letters

authors： Hoshi A,Tsunoda A,Yamamoto T,Tada M,Kakita A,Ugawa Y

更新日期：2016-07-28 00:00:00

abstract：:Studies have demonstrated the changes of the physiological characteristics of nucleus accumbens (NAc) neurons with the postnatal development of rats. In the present study, spontaneous excitatory postsynaptic currents (sEPSCs) were recorded in the slices of NAc shell (NAcS) of adult and juvenile rats. Our results demon...

journal_title：Neuroscience letters

authors： Liu XD,Liu Z,Kong QY,Zhang JJ,Wang Y,Yu LC

更新日期：2011-06-01 00:00:00

abstract：:Electrophysiological and biochemical studies have indicated that GABAergic modulation is involved in the opioid-induced altering of response properties of visual cortical cells and impairing of short-term synaptic plasticity in the geniculo-cortical visual pathway. The aim of the current study was to examine whether t...

journal_title：Neuroscience letters

authors： Li Y,He L,Chen Q,Zhou Y

更新日期：2007-11-20 00:00:00

abstract：:Patients with schizophrenia are especially impaired in the detection of spatial location if the briefly presented target stimulus is followed by a mask in a close temporal proximity (target location backward masking (BM) paradigm). It has been suggested that this phenomenon is related to the impairment of low spatial ...

journal_title：Neuroscience letters

authors： Kéri S,Antal A,Szekeres G,Benedek G,Janka Z

更新日期：2000-10-20 00:00:00

abstract：:Intracerebral hemorrhage is associated with stroke and head trauma. The purpose of this study was to study brain inflammation and cell death in adult rats 1 h to 4 weeks after injection of blood into the striatum. Terminal dUTP nick-end-labeling positive dying cells were evident 4 h to 4 weeks post-hemorrhage. Neutrop...

journal_title：Neuroscience letters

authors： Xue M,Del Bigio MR

更新日期：2000-04-14 00:00:00

abstract：:Genetic factors have been reported to contribute to the liability of suicide. We aimed to investigate functional polymorphisms in eight genes (serotonin transporter, SLC6A4; receptors, 5HTR1A, 1B, 5HTR2A; Tryptophan Hydroxylase, TPH1, TPH2; Monoamine Oxidase, MAOA and G Protein Subunit Beta 3, GNB3) to investigate the...

journal_title：Neuroscience letters

authors： Pompili M,Gentile G,Scassellati C,Bonvicini C,Innamorati M,Erbuto D,Montebovi F,Ducci G,Forte A,De Pisa E,Ferracuti S,Serafini G,De Luca V,Amore M,Simmaco M,Girardi P

更新日期：2017-08-24 00:00:00

abstract：:Exposure to a single session of intense inescapable stressors results in elevations of plasma corticosterone levels selective to the trough of the circadian rhythm that last for several days after stressor cessation. In the present study, we examined whether this stress-induced alteration in the regulation of the circ...

journal_title：Neuroscience letters

authors： Moldow RL,Beck KD,Weaver S,Servatius RJ

更新日期：2005-02-01 00:00:00

abstract：:In the present study we investigated the effect of electrolytic lesion of the medial septal area (MSA) on the dipsogenic, natriuretic, kaliuretic and pressor responses elicited by intracerebroventricular (i.c.v.) injection of the cholinergic agonist carbachol. Freely moving rats with sham or MSA lesion (1-7 days and 1...

journal_title：Neuroscience letters

authors： Luiz AC,Saad WA,Camargo LA,Renzi A,De Luca Junior LA,Menani JV

更新日期：1991-11-11 00:00:00

abstract：:Tumor related contralateral motor deficits complicate preoperative functional magnetic resonance imaging (fMRI). In plegic patients the localization of the sensorimotor cortex is often impossible. In this context we developed a clinical fMRI protocol dedicated to patients with motor deficits using the unaffected ipsil...

journal_title：Neuroscience letters

authors： Stippich C,Kapfer D,Hempel E,Borgulya G,Bongers A,Heiland S,Sartor K

更新日期：2000-05-12 00:00:00

abstract：:Telmisartan is known to block angiotensin (Ang) II type-1 receptors (AT(1)R), and also activate peroxisome proliferator-activated receptor gamma (PPARgamma) signaling. Recently, PPARgamma has been implicated as a regulator of cellular proliferation and inflammatory responses. In the present study, we investigated the ...

journal_title：Neuroscience letters

authors： Haraguchi T,Takasaki K,Naito T,Hayakawa K,Katsurabayashi S,Mishima K,Iwasaki K,Fujiwara M

更新日期：2009-10-30 00:00:00

abstract：:Nogo-A has been identified as an inhibitory molecule to neurite outgrowth after injury in adult mammalian central nervous system (CNS). The C-terminal fragment of Nogo-A, Nogo-66, inhibits axonal regrowth through NgR1 signaling. Residues 1-32 of Nogo-66 cover two regions that contribute most affinity of Nogo-66 to NgR...

journal_title：Neuroscience letters

authors： Deng Q,Cai W,Li S,Su B

更新日期：2013-03-01 00:00:00

abstract：:Chlorogenic acid (CGA) is one of the most abundant polyphenol compounds in the human diet. Recently, it is demonstrated to have potent antinociceptive effect. However, little is understood about the mechanism underlying CGA analgesia. Here, we have found that CGA can exert an inhibitory effect on the functional activi...

journal_title：Neuroscience letters

authors： Qu ZW,Liu TT,Qiu CY,Li JD,Hu WP

更新日期：2014-05-01 00:00:00

abstract：:Paramethoxyphenylethylamine (PMPEA) is a sympathomimetic amine, like its parent compound, phenylethylamine. The intraperitoneal administration of PMPEA to mice produces a dose-dependent depletion of brain and heart norepinephrine, with significant reduction being observed one hour postinjection. At lower dosages, PMPE...

journal_title：Neuroscience letters

authors： Ashkenazi R,Haber B

更新日期：1975-09-01 00:00:00

abstract：:Face processing is unique to human beings and is likely to have special neuronal properties. We studied one of these properties, categorical representation of the face in perception processing (perception) and in memory recall processing (imagery), using the face and building stimuli. The same building-selective areas...

journal_title：Neuroscience letters

authors： Sung YW,Ogawa S

更新日期：2008-12-19 00:00:00

abstract：:The contribution of angiotensin II (Ang II) to the pathophysiology of hypertension is established based on facts that high levels of circulating Ang II increase vasoconstriction of peripheral arteries causing a rise in blood pressure (BP). In addition, circulating Ang II has various effects on the central nervous syst...

journal_title：Neuroscience letters

authors： Issa AT,Miyata K,Heng V,Mitchell KD,Derbenev AV

更新日期：2012-06-21 00:00:00

abstract：:Using collision tests of orthodromically and antidromically generated spikes, we studied the axonal pathways, axonal projection levels, and soma location of anterior semicircular canal (AC) nerve-activated vestibulospinal neurons in decerebrate cats. AC nerve-activated vestibulospinal neurons (n=74) were mainly locate...

journal_title：Neuroscience letters

authors： Kitajima N,Sugita-Kitajima A,Bai R,Sasaki M,Sato H,Imagawa M,Kawamoto E,Suzuki M,Uchino Y

更新日期：2006-10-02 00:00:00

abstract：:We determined the concentrations of the putative transmitter amino acids in the cerebrospinal fluid of patients with Alzheimer type dementia (ATD) and vascular dementia of the Binswanger type (VDBT). In ATD, aspartate and glutamate concentrations were significantly and selectively reduced, while in VDBT, concentration...

journal_title：Neuroscience letters

authors： Tohgi H,Abe T,Takahashi S,Kimura M

更新日期：1992-07-06 00:00:00

abstract：:Transcranial direct current stimulation (tDCS) is a non-invasive technique that moderates cognitive and motor function. The effects of tDCS on cognitive and motor tasks vary among individuals. However, the source of the inter-individual variability remains unknown. The purpose of the present study was to examine wheth...

journal_title：Neuroscience letters

authors： Kasahara K,Tanaka S,Hanakawa T,Senoo A,Honda M

更新日期：2013-06-17 00:00:00

abstract：BACKGROUND:Diverse physiological and pathological functions of 27-hydroxycholesterol (27-OHC) were proved. However, cytotoxicity and potential influence of 27-OHC on cholesterol metabolism in neurons are unclear. DESIGN AND METHODS:In the vitro co-culture system, SH-SY5Y cells and C6 cells were applied to explore the ...

journal_title：Neuroscience letters

authors： Wang H,Yuan L,Ma W,Han J,Lu Y,Feng L,Xiao R

更新日期：2016-10-06 00:00:00

abstract：:These experiments show that a synaptic response, namely the late inhibitory postsynaptic potential (IPSP) of hippocampal CA3 neurons of rats, is blocked by pertussis toxin, an inactivator of several GTP-binding proteins (G-proteins) excluding the G-protein that stimulates adenylyl cyclase. This blockage occurred witho...

journal_title：Neuroscience letters

authors： Thalmann RH

更新日期：1987-11-10 00:00:00

abstract：:The processing of sound information is mediated by the cochlea and the central auditory system. Among the central auditory system, the inferior colliculus (IC) has leading roles in the acoustic processing. In a previous study, we demonstrated psychiatric disorder-related behavioral abnormalities in a genetically modif...

journal_title：Neuroscience letters

authors： Nakajima M,Nishikawa C,Miyasaka Y,Kikkawa Y,Mori H,Tsuruta M,Okuyama S,Furukawa Y

更新日期：2014-04-30 00:00:00

abstract：:Using specific radioimmunoassays, melatonin was quantified in the aqueous humor and serum of male pigmented rabbits adapted to 12L:12D with lights on at 06.00 h. Melatonin concentrations in the aqueous humor at 08.00 and 16.00 h were similar (mean: 5.23 pg/ml) and significantly lower than those at 22.00 and 01.00 h (m...

journal_title：Neuroscience letters

authors： Yu HS,Yee RW,Howes KA,Reiter RJ

更新日期：1990-08-24 00:00:00

abstract：:Several studies have reported the presence of methylphenidate (MPH) in effluents; however, its impacts on aquatic life are not yet well understood. Here, we investigated the effects of acute exposure on endocrine and behavioral stress responses to environmentally relevant concentrations of MPH in zebrafish. We show th...

journal_title：Neuroscience letters

authors： Endres HC,da Rosa JG,Kabasele Kalala C,Barcellos HH,Bertol CD,Gil Barcellos LJ,Rossato-Grando LG

更新日期：2017-05-22 00:00:00

abstract：:We have looked at the effect of synthetic mu-conotoxin GIIIA, a selective blocker of muscle Na channels, on various parameters of synaptic transmission at the frog sartorius nerve-muscle preparation. We found that 5 microM mu-conotoxin consistently blocked muscle action potentials, but had no effect on nerve action po...

journal_title：Neuroscience letters

authors： Sosa MA,Zengel JE

更新日期：1993-07-23 00:00:00

abstract：:The effect of electrical stimulation of the dorsal hippocampus on accumbens dopamine release was examined. Stimulation of the kindled hippocampus that produced stage 3 seizures evoked a brief increase in extracellular DA and DOPAC levels in the contralateral nucleus accumbens. In contrast, similar stimulation early in...

journal_title：Neuroscience letters

authors： Strecker RE,Moneta ME

更新日期：1994-08-01 00:00:00

abstract：:N-omega-[18F]fluoroethylketanserin ([18F]FEK), an 18F-labeled analogue of the serotonin S2 antagonist ketanserin, was evaluated for use with positron emission tomography (PET). PET imaging of a baboon brain following injection of [18F]FEK indicated that the fluorinated ligand rapidly localized in vivo within S2 recept...

journal_title：Neuroscience letters

authors： Moerlein SM,Perlmutter JS

更新日期：1991-02-11 00:00:00

abstract：:Interaction of beta-adrenergic and somatostatinergic systems in the hippocampus has not been investigated fully. We studied the influence of DL-isoproterenol (ISO), a beta-adrenergic agonist and DL-propranolol (PRO), a beta-adrenergic blocking agent, on the somatostatinergic system in the rat hippocampus. The short-(5...

journal_title：Neuroscience letters

authors： López-Sañudo S,Arilla E

更新日期：1994-01-03 00:00:00