Central serotonergic S2 binding in Papio anubis measured in vivo with N-omega-[18F]fluoroethylketanserin and PET.

abstract：:Neural stem cells (NSCs) persist in the mammalian brain throughout life and protect against hypoxia-ischemia injury. NSCs are being increasingly recognized as a novel therapeutic target for various neurological disorders. Previous research indicates that miR-21 attenuates hypoxia-ischemia induced apoptotic death in va...

journal_title：Neuroscience letters

authors： Chen R,Tai Y,Zhang Y,Wang L,Yang Y,Yang N,Ma S,Xue F,Wang J

更新日期：2019-01-18 00:00:00

abstract：:Intracellular recordings were made from neurons in rabbit vesical pelvic ganglia (VPG), in vitro. Increasing the frequency of preganglionic-nerve stimulations from 0.1-1 Hz to 10-20 Hz facilitated fast excitatory postsynaptic potentials (EPSPs), resulting in a generation of action potentials. Acetylcholine-induced res...

journal_title：Neuroscience letters

authors： Nishimura T,Yoshida M,Nagatsu I,Akasu T

更新日期：1989-08-28 00:00:00

abstract：:In this study, we investigated the eye movement and postural control performance in dyslexic children while reading text and performing Landolt reading when sitting and standing. Fifteen dyslexic and 15 non-dyslexic children were asked to sit in a chair while the eye movements were recorded, and were then asked to sta...

journal_title：Neuroscience letters

authors： Razuk M,Barela JA,Peyre H,Gerard CL,Bucci MP

更新日期：2018-11-01 00:00:00

abstract：:Excessive activation of the N-methyl-D-aspartate (NMDA) receptor-channel complex has been implicated as one of the mechanisms by which ischemia-induced neuronal damage is mediated. Elevated glycine levels during ischemia may contribute to damage mediated by the NMDA receptor as glycine binding potentiates NMDA respons...

journal_title：Neuroscience letters

authors： Wood ER,Bussey TJ,Phillips AG

更新日期：1992-09-28 00:00:00

abstract：:Interaction of beta-adrenergic and somatostatinergic systems in the hippocampus has not been investigated fully. We studied the influence of DL-isoproterenol (ISO), a beta-adrenergic agonist and DL-propranolol (PRO), a beta-adrenergic blocking agent, on the somatostatinergic system in the rat hippocampus. The short-(5...

journal_title：Neuroscience letters

authors： López-Sañudo S,Arilla E

更新日期：1994-01-03 00:00:00

abstract：:The induction of heme oxygenase-1 (HO-1), the 32 kDa heat shock protein, was examined in the traumatized rat brain. At 24 h after either mild or severe brain injury or sham surgery, HO-1 was immunolocalized in fixed sections of brain. After mild brain injury, hemorrhage was apparent in the subarachnoid space, external...

journal_title：Neuroscience letters

authors： Fukuda K,Panter SS,Sharp FR,Noble LJ

更新日期：1995-10-20 00:00:00

abstract：:It has been proposed that the perception of a coherent image necessitates two processes, that is, an ensemble of neurons which synchronizes discharges of individual cells and stimulus-specific gamma-band (gamma) neuronal oscillations which may serve as carrier signals for a temporal code. We tested the hypothesis that...

journal_title：Neuroscience letters

authors： Shumikhina S,Molotchnikoff S

更新日期：1999-09-10 00:00:00

abstract：:Most fibres in adult muscles are derived from secondary myotubes which form around an earlier developing population of primary myotubes. We examined embryonic rat IVth lumbrical muscles at a stage when most secondary myotubes were less than 24 h old, in order to study their acquisition of synaptic terminals. Single ne...

journal_title：Neuroscience letters

authors： Duxson MJ,Ross JJ,Harris AJ

更新日期：1986-11-11 00:00:00

abstract：:The role of intracellular amyloid beta (iAbeta) in Alzheimer's disease (AD) initiation and progression attracts more and more attention in recent years. To address whether iAbeta induces early alterations of electrophysiological properties in cultured human primary neurons, we delivered iAbeta with adeno-virus and mea...

journal_title：Neuroscience letters

authors： Hou JF,Cui J,Yu LC,Zhang Y

更新日期：2009-10-25 00:00:00

abstract：:Based on its proposed ability to block the effect of selective serotonin reuptake inhibitors (SSRIs) on the firing rate of serotonergic neurons, the 5-HT1A partial agonist/beta-adrenergic antagonist pindolol has been examined in clinical trials for its ability to enhance the efficacy of SSRIs. However, varying results...

journal_title：Neuroscience letters

authors： Rasmussen K,McCreary AC,Shanks EA

更新日期：2004-01-23 00:00:00

abstract：:The interleukin-6 (IL-6) family of cytokines is thought to be involved in the development and regeneration of peripheral nerves; however, their roles in myelination remain unclear. In this study, we examined the effects of IL-6 on the expression of genes for compact myelin proteins using Schwann cell cultures prepared...

journal_title：Neuroscience letters

authors： Ito T,Ikeda K,Tomita K,Yokoyama S

更新日期：2010-03-19 00:00:00

abstract：:Dendritic degeneration is a common pathology in temporal lobe epilepsy and its animal models. However, little is known when and how the degeneration occurs. In the present study of the rat pilocarpine model, visualization of dendrites of the hippocampal dentate granule cells (DGCs) by biocytin revealed a generalized s...

journal_title：Neuroscience letters

authors： Isokawa M

更新日期：1998-12-18 00:00:00

abstract：:Technologies for wireless telecommunication systems using millimeter waves (MMW) will be widely deployed in the near future. Forthcoming applications in this band, especially around 60GHz, are mainly developed for high data-rate local and body-centric telecommunications. At those frequencies, electromagnetic radiation...

journal_title：Neuroscience letters

authors： Haas AJ,Le Page Y,Zhadobov M,Sauleau R,Le Dréan Y

更新日期：2016-04-08 00:00:00

abstract：:Cognitive impairment in Parkinson's disease is accompanied by a marked decrease of cerebrocortical nicotinic receptors. To study the putative site of impaired receptor synthesis, frontal cortices of Parkinson patients with cognitive dysfunction have been screened for the expression of the nicotinic receptor alpha 4 su...

journal_title：Neuroscience letters

authors： Schröder H,de Vos RA,Jansen EN,Birtsch C,Wevers A,Lobron C,Nowacki S,Schröder R,Maelicke A

更新日期：1995-03-10 00:00:00

abstract：:Drug addiction is a process that transits from recreative and regular drug use into compulsive drug use. The two patterns of drug use, controlled drug intake and escalated drug intake, represent different stages in the development of drug addiction; and escalation of drug use is a hallmark of addiction. Accumulating s...

journal_title：Neuroscience letters

authors： Du HY,Cao DN,Chen Y,Wang L,Wu N,Li J

更新日期：2016-01-12 00:00:00

abstract：:A two-stage model of sustained neural activity in the prefrontal cortex is proposed in order to simulate feature binding and capacity limits in visual working memory. In the first stage, object features are stored in parallel network layers without explicit conjunctions. A second stage binds features into integrated o...

journal_title：Neuroscience letters

authors： Domijan D

更新日期：2003-10-23 00:00:00

abstract：:The representation of time, space and numbers are strictly linked in the primate's cognitive system. Here we show that merely looking at number symbols biases a temporal judgment on their duration depending upon the number's magnitude. In a first experiment, a group of healthy subjects was submitted to a time estimati...

journal_title：Neuroscience letters

authors： Oliveri M,Vicario CM,Salerno S,Koch G,Turriziani P,Mangano R,Chillemi G,Caltagirone C

更新日期：2008-06-27 00:00:00

abstract：:Previous studies have shown that the midbrain periaqueductal gray (PAG) projects to the ventrolateral medulla (VLM). Here, we studied PAG projections to the area of A1/C1 neurons in the VLM in the rat using phaseolus vulgaris leucoagglutinin (PHA-L) anterograde tracing combined with immunocytochemistry for tyrosine hy...

journal_title：Neuroscience letters

authors： Chen S,Aston-Jones G

更新日期：1995-08-04 00:00:00

abstract：:Heat shock proteins (Hsps) have been regarded as cytoprotectants that protect brain cells from damage encountered following cerebral ischemia or during the progression of neurodegenerative diseases. In this study, we assessed the plasma Hsp70 and Hsp27 levels in not cognitively impaired (NCI) subjects and in patients ...

journal_title：Neuroscience letters

authors： Lee KS,Chung JH,Oh BH,Hong CH

更新日期：2008-05-09 00:00:00

abstract：:The role of the serotonergic system in regulating the expression of estrogen receptor (ER) α in the hypothalamus was investigated in ovariectomized rats by injecting a serotonin synthesis inhibitor, parachlorophenylalanine (PCPA), or by destroying the dorsal raphe nucleus (DR). The number of ERα-immunoreactive (ir) ce...

journal_title：Neuroscience letters

authors： Ito H,Shimogawa Y,Kohagura D,Moriizumi T,Yamanouchi K

更新日期：2014-11-07 00:00:00

abstract：:Small-fiber neuropathy was induced in young adult mice by intraperitoneal injection of resiniferatoxin (RTX), a TRPV1 agonist. At day 7, RTX induced significant thermal and mechanical hypoalgesia. At day 28, mechanical and thermal nociception were restored. No nerve degeneration in skin was observed and unmyelinated n...

journal_title：Neuroscience letters

authors： Danigo A,Magy L,Richard L,Sturtz F,Funalot B,Demiot C

更新日期：2014-06-13 00:00:00

abstract：:Excess cholesterol is removed from the brain via hydroxylation mediated by cholesterol 24S-hydroxylase (CYP46). Although serum and cerebrospinal fluid (CSF) concentrations of 24S-hydroxycholesterol are altered during the progress of Alzheimer's disease, studies carried out to date in different populations on the assoc...

journal_title：Neuroscience letters

authors： Golanska E,Hulas-Bigoszewska K,Wojcik I,Rieske P,Styczynska M,Peplonska B,Pfeffer A,Luczywek E,Wasiak B,Gabryelewicz T,Religa D,Chodakowska-Zebrowska M,Barcikowska M,Sobow T,Liberski PP

更新日期：2005-07-22 00:00:00

abstract：:The aims of the present work were to evaluate the exploratory activity in Sprague-Dawley rats, as well as to analyze the nigral and striatal mRNA expression of the plasticity-related genes bdnf and arc after L-buthionine sulfoximine (BSO) injection into substantia nigra compacta. Lesioned rats traveled less distance i...

journal_title：Neuroscience letters

authors： Díaz-Hung ML,Ruiz-Fuentes JL,Díaz-García A,León-Martínez R,Alberti-Amador E,Pavón-Fuentes N,Blanco-Lezcano L

更新日期：2018-11-20 00:00:00

abstract：:There is evidence suggesting that exposure to an abnormal magnetic environment may produce psychophysiological effects related to abnormalities in responses to stress. This may be of relevance for space medicine where astronauts are exposed to a magnetic field different from that exerted by the Earth. Aim of this stud...

journal_title：Neuroscience letters

authors： Del Seppia C,Mezzasalma L,Messerotti M,Cordelli A,Ghione S

更新日期：2006-06-12 00:00:00

abstract：:Bilateral injections of the GABA(A) agonist muscimol into the lateral parabrachial nucleus (LPBN) disrupt satiety and induce strong ingestion of water and 0.3M NaCl in fluid-replete rats by mechanisms not completely clear. In the present study, we investigated the effects of the blockade of central muscarinic choliner...

journal_title：Neuroscience letters

authors： Asnar DS,Roncari CF,De Luca LA Jr,de Paula PM,Colombari DS,Menani JV

更新日期：2013-02-08 00:00:00

abstract：:The content of two neuropeptides, somatostatin (SRIF) and neuropeptide Y (NPY) has been determined in two cerebral cortical areas of Alzheimer's disease brain and in age-matched control brains. The content of SRIF-like immunoreactivity (SRIF-LI) was found to be decreased in Alzheimer temporal cortex (Brodmann area 21)...

journal_title：Neuroscience letters

authors： Dawbarn D,Rossor MN,Mountjoy CQ,Roth M,Emson PC

更新日期：1986-09-25 00:00:00

abstract：:Parkinson's disease (PD) is a multifactorial disease caused by both genetic and environmental factors. Alpha-synuclein is of particular interest in PD since it is a major component of Lewy bodies and mutations in the alpha-synuclein gene were identified in familial PD. Oxidative stress and proteasomal dysfunction are ...

journal_title：Neuroscience letters

authors： Lev N,Melamed E,Offen D

更新日期：2006-05-15 00:00:00

abstract：:Proton-induced Na+ currents (INa(H] were measured in precursor cells from chick dorsal root ganglia with whole-cell patch-clamp recording. Precursor cells were isolated using the method of Rohrer et al. (EMBO. J., 4 (1985) 1709-1714) and fast pH changes were applied with a technique developed by Davies et al. (J. Phys...

journal_title：Neuroscience letters

authors： Gottmann K,Dietzel ID,Lux HD,Ruedel C

更新日期：1989-04-24 00:00:00

abstract：:Pain consists of sensory and negative affective components. Using a conditioned place aversion (CPA) paradigm, we investigated whether the medial thalamus (MT) played a role in the affective component of visceral pain induced by intraperitoneal injection of acetic acid into male Long-Evan rats. Acetic acid produced wr...

journal_title：Neuroscience letters

authors： Wang HC,Chai SC,Wu YS,Wang CC

更新日期：2007-06-08 00:00:00

abstract：:Neuronal voltage-dependent P/Q Ca2+ channels are genetically abnormal in many cases of familial hemiplegic migraine and possibly associated with the more common forms of migraine with and without aura. Besides the brain, these channels are found in motor nerve endings where they control stimulation-induced acetylcholi...

journal_title：Neuroscience letters

authors： Ambrosini A,de Noordhout AM,Alagona G,Dalpozzo F,Schoenen J

更新日期：1999-12-10 00:00:00