Proton-induced Na+ current develops prior to voltage-dependent Na+ and Ca2+ currents in neuronal precursor cells from chick dorsal root ganglion.

Abstract:

:Proton-induced Na+ currents (INa(H] were measured in precursor cells from chick dorsal root ganglia with whole-cell patch-clamp recording. Precursor cells were isolated using the method of Rohrer et al. (EMBO. J., 4 (1985) 1709-1714) and fast pH changes were applied with a technique developed by Davies et al. (J. Physiol. (Lond.), 400 (1988) 159-187). Proton-induced transient Na+ currents showing the same properties as in more mature neurons could be elicited already early in differentiation, before high-voltage activated Ca2+ currents and voltage-dependent Na+ currents develop.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Gottmann K,Dietzel ID,Lux HD,Ruedel C

doi

10.1016/0304-3940(89)90270-x

subject

Has Abstract

pub_date

1989-04-24 00:00:00

pages

90-4

issue

1-2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(89)90270-X

journal_volume

99

pub_type

杂志文章
  • Electroretinograms remain normal in mice lacking a synapse associated protein.

    abstract::Integrin-associated protein (IAP) is normally localized to the synapse rich plexiform layers of the mammalian retina. In other neuronal systems, IAP and its ligand, P84, have been implicated in synaptic function. Previously, an abnormal distribution of P84 was noted in the IAP-null retina. To examine the potential rol...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(00)01743-2

    authors: Ball SL,Lindberg FP,Lagenaur CF,Peachey NS

    更新日期:2001-02-02 00:00:00

  • Comparison through immunoblotting of glutamic acid decarboxylase (GAD) from newborn and adult rat brain.

    abstract::Immunochemical characterization of glutamic acid decarboxylase (GAD) from brain extracts of newborn and adult rats was investigated using a GAD antiserum that was previously raised against brain GAD from adult rats. According to the immunoprecipitation and saturation curves, no significant differences could be found a...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(89)90703-9

    authors: Henry S,Tappaz M

    更新日期:1989-05-22 00:00:00

  • The 'M2' electromyographic response to random perturbations of arm movements is missing in long-trained monkeys.

    abstract::Adult monkeys who have been under training over a long period of time show a loss of the M2 component in their biceps electromyographic response to brief, random perturbations of an alternating arm movement, the M1 component being apparently enhanced. These changes of the stretch-induced responses indicate a long-term...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(83)90466-4

    authors: Christakos CN,Wolf H,Meyer-Lohmann J

    更新日期:1983-11-11 00:00:00

  • Changes of regional cerebral blood flow during listening to an unfamiliar spoken language.

    abstract::The regional cerebral blood flow (rCBF) was measured with positron emission tomography in eight normal volunteers with the purpose of measuring rCBF changes related to the comprehension of an unfamiliar spoken languages. When attempting to comprehend the meaning of words, the left hemisphere showed dominant increases ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(93)90142-8

    authors: Kawashima R,Itoh M,Hatazawa J,Miyazawa H,Yamada K,Matsuzawa T,Fukuda H

    更新日期:1993-10-14 00:00:00

  • Changes in basal and stimulated release of endogenous serotonin from different nuclei of rats subjected to two models of depression.

    abstract::Basal serotonin (5-HT) release, measured in the presence of imipramine, was significantly reduced in slices of hippocampus, n. accumbens and frontal cortex from rats subjected to forced swim test and chronic isolation. Only in the hippocampus, in the two animal models of depression, K-stimulated release was increased....

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(93)90584-8

    authors: Jaffe EH,De Frias V,Ibarra C

    更新日期:1993-11-12 00:00:00

  • Structural specializations in cat of chronically demyelinated spinal cord axons as seen in freeze-fracture replicas.

    abstract::Axons in chronically demyelinated spinal cord lesions, induced by ethidium bromide injection, display patches of intramembranous particles and indentations resembling nodal and paranodal axolemmal specializations respectively. Both occur in the marginal region of the lesions where the demyelinated axons are intimately...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(84)90015-6

    authors: Rosenbluth J,Blakemore WF

    更新日期:1984-07-27 00:00:00

  • Lateralization of activity in the parietal cortex predicts the effectiveness of bilateral transcranial direct current stimulation on performance of a mental calculation task.

    abstract::Transcranial direct current stimulation (tDCS) is a non-invasive technique that moderates cognitive and motor function. The effects of tDCS on cognitive and motor tasks vary among individuals. However, the source of the inter-individual variability remains unknown. The purpose of the present study was to examine wheth...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2013.04.022

    authors: Kasahara K,Tanaka S,Hanakawa T,Senoo A,Honda M

    更新日期:2013-06-17 00:00:00

  • Neurite outgrowth is enhanced by conditioning factor(s) released from central ganglia of Aplysia californica.

    abstract::Single neurons of Aplysia californica were cultured on control and conditioned medium-treated cover slips (CM, derived from central ganglia of Aplysia) and fed with L-15 medium plus 20% hemolymph. After 5 h 36.9 +/- 3.3% of all neurons plated on CM-treated cover slips sprouted, whereas only 22.9 +/- 2.7% sprouted in t...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(95)12004-n

    authors: Fejtl M,Carpenter DO

    更新日期:1995-10-13 00:00:00

  • Changes in human diaphragmatic electromyogram with positive pressure breathing.

    abstract::An increase in diaphragmatic electromyogram (EMG) recorded via oesophageal electrodes during positive pressure breathing has been reported to indicate an increase in the neural outflow to the muscle. However, using similar techniques, the size of compound muscle action potentials produced by supramaximal phrenic nerve...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(86)90442-8

    authors: McKenzie DK,Gandevia SC

    更新日期:1986-09-25 00:00:00

  • Protective effects of S-nitrosoglutathione against neurotoxicity of 3-nitropropionic acid in rat.

    abstract::Mitochondrial dysfunction and oxidative stress are often linked to various neurodegenerative disorders including ischemic stroke and Huntington's disease (HD). S-Nitrosoglutathione (GSNO) is an endogenous nitric oxide carrier recently identified as a potent antioxidant capable of neutralizing oxidative stress. In the ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2004.03.028

    authors: Ju TC,Yang YT,Yang DI

    更新日期:2004-05-27 00:00:00

  • Compression-induced ATP release from rat skeletal muscle with and without lengthening contraction.

    abstract::Adenosine triphosphate (ATP) is well known to be released from injured or inflamed tissues, and to excite/sensitize nociceptors in response to heat and mechanical stimulation. To determine whether muscle releases ATP when it is compressed, we measured ATP release from the extensor digitorum longus muscle (EDL). In add...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2008.01.068

    authors: Taguchi T,Kozaki Y,Katanosaka K,Mizumura K

    更新日期:2008-04-04 00:00:00

  • Increase of spiny I activity in striatum after development of context-dependent sensitization of catalepsy in rats.

    abstract::In this study, it was investigated whether context-dependent sensitization of catalepsy changes the firing pattern in striatum. Rats were treated with either haloperidol (0.5 mg/kg i.p.) or saline, and tested on catalepsy with a concomitant single-unit measurement of the spiny I activity. Administration of haloperidol...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2003.09.020

    authors: Frank ST,Schmidt WJ

    更新日期:2004-01-02 00:00:00

  • Inhibition of ganglioside synthesis reduces the neuronal survival activity of astrocytes.

    abstract::Gangliosides are sialic acid-containing sphingolipids that have promoting effects on the survival, growth, and functions of neurons in the central nervous system. Glial cells including astrocytes assist neurons with regard to their proliferation, maintenance, and function. In the present study, we found that astrocyte...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2010.11.029

    authors: Akasako Y,Nara K,Nagai Y,Hashimoto Y

    更新日期:2011-01-20 00:00:00

  • Age-dependent and selective binding of beta-bungarotoxin to GABAergic neurons in the rat cerebellum.

    abstract::beta-Bungarotoxin (BuTx)-binding cells were immunocytochemically examined in the developing rat cerebellum. The tissue was incubated with BuTx and then immunostained with antiserum against its toxoid. On postnatal day 6, only Golgi cells were positive for immunoreaction. Immunoreactive Golgi cells were reduced in numb...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(87)90187-x

    authors: Katoh-Semba R,Semba R,Kashiwamata S

    更新日期:1987-04-23 00:00:00

  • Intelligence related differences in EEG-bandpower.

    abstract::Several studies on the relationship between event-related desynchronization/synchronization (ERD/ERS) and cognitive performance revealed contradictory results particularly for the alpha band. Studies from our laboratory have shown that good performers show a larger upper alpha ERD (interpreted in terms of larger corti...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2005.02.037

    authors: Doppelmayr M,Klimesch W,Sauseng P,Hödlmoser K,Stadler W,Hanslmayr S

    更新日期:2005-06-24 00:00:00

  • Tyrosine augments clozapine-induced dopamine release in the medial prefrontal cortex of the rat in vivo: effects of access to food.

    abstract::It has been reported that tyrosine administration augments clozapine-induced dopamine (DA) release in the medial prefrontal cortex (MPFC). To characterize this effect and exclude possible confounds, we conducted a series of studies in which microdialysate collection started 24 h after probe implantation, a time at whi...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2003.11.060

    authors: Jaskiw GE,Simpson C,Bongiovanni R,Yamamoto BK

    更新日期:2004-02-26 00:00:00

  • Aging of the cingulum in the human brain: Preliminary study of a diffusion tensor imaging study.

    abstract::The cingulum, a major structure of the limbic system, is closely associated with memory function. In the current study, we investigated aging of the cingulum according to the location of the cingulum in each part of the cingulum after dividing the cingulum into five parts in normal subjects, using DTT parameters (frac...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2015.11.018

    authors: Jang SH,Kwon YH,Lee MY,Kim JR,Seo JP

    更新日期:2016-01-01 00:00:00

  • L-AP4 inhibition of depolarization-evoked cGMP formation in rat cerebellum.

    abstract::The effects of the group III mGluR agonist, L-2-amino-4-phosphonobutyrate (L-AP4), on depolarization-stimulated cGMP levels in adult rat cerebellar slices were determined. L-AP4 elicited a concentration-dependent, complete inhibition of cGMP formation stimulated by 4-aminopyridine (4-AP; 1 mM), yielding an IC50 value ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(97)00402-3

    authors: Cartmell J,Kemp JA,Mutel V

    更新日期:1997-06-13 00:00:00

  • DNA versus RNA oxidation in Parkinson's disease: Which is more important?

    abstract:BACKROUND:8-hydroxy-2 deoxyguanosine (8-OHdG) and the 8-hydroxyguanosine (8-OHG) are the most widely used biomarkers of nucleoside oxidation affecting DNA and RNA and are considered reliable markers of oxidative stress. Increased levels of these markers are found in the various biological fluids of patients with neurod...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2017.09.048

    authors: Gmitterová K,Gawinecka J,Heinemann U,Valkovič P,Zerr I

    更新日期:2018-01-01 00:00:00

  • Bradykinin preconditioning induces protective effects on the spinal cord ischemic injury of rats.

    abstract::The study was performed to investigate the effects of bradykinin preconditioning on spinal cord ischemic injury using an in vivo transient spinal cord ischemia model in rats. Prior to ischemia, bradykinin was infused continuously via the left femoral artery starting 15min before ischemia. Neurological functions were e...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2008.01.010

    authors: Yan-Feng W,Gang L,Yan-Ting G

    更新日期:2008-03-12 00:00:00

  • Postischemic expression of P-selectin immunoreactivity in rat brain.

    abstract::Change of immunoreactive P-selectin was examined in rat brain after transient middle cerebral artery (MCA) occlusion (O) with anti-P-selectin monoclonal antibody using brain samples of sham control and after ischemia. Temporal, spatial, and cellular changes of immunohistochemical expressions of P-selectin were evaluat...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(97)00385-6

    authors: Suzuki H,Abe K,Tojo S,Morooka S,Kimura K,Mizugaki M,Itoyama Y

    更新日期:1997-06-13 00:00:00

  • Analysis of the MRPL3, DNAJC13 and OFCC1 variants in Chinese Han patients with TS-CTD.

    abstract::Tourette syndrome/chronic tic phenotype (TS-CTD) is a neurological disorder manifested particularly by motor and vocal tics and associated with a variety of behavioral abnormalities. Recently, the mitochondrial ribosomal protein L3 gene (MRPL3) S75N, the DnaJ (Hsp40) homolog subfamily C member 13 gene (DNAJC13) A2057S...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2012.03.097

    authors: Guo Y,Deng X,Zhang J,Su L,Xu H,Luo Z,Deng H

    更新日期:2012-05-23 00:00:00

  • Different physiological properties of spontaneous excitatory postsynaptic currents in nucleus accumbens shell neurons between adult and juvenile rats.

    abstract::Studies have demonstrated the changes of the physiological characteristics of nucleus accumbens (NAc) neurons with the postnatal development of rats. In the present study, spontaneous excitatory postsynaptic currents (sEPSCs) were recorded in the slices of NAc shell (NAcS) of adult and juvenile rats. Our results demon...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2011.03.086

    authors: Liu XD,Liu Z,Kong QY,Zhang JJ,Wang Y,Yu LC

    更新日期:2011-06-01 00:00:00

  • In vivo administration of valproate reduces the nerve terminal (synaptosomal) activity of GABA aminotransferase in discrete brain areas of rats.

    abstract::Previous in vitro experiments have indicated that neuronal GABA aminotransferase (GABA-T) differs from extraneuronal GABA-T in sensitivity to certain enzyme inhibitors, including the antiepileptic drug valproate (VPA). In the present experiments, it was studied if GABA-T activity in whole tissue and synaptosomes prepa...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(93)90407-c

    authors: Löscher W

    更新日期:1993-10-01 00:00:00

  • Thermoreceptive neurons in the dorsal portion of the trigeminal principal nucleus in rats.

    abstract::The dorsal margin of the trigeminal principal nucleus (PV) contains neurons responsive to innocuous thermal stimulation of the tongue and maybe a thermal relay (Hayama and Hashimoto, 2011). The present electrophysiological study examined whether PV thermoreceptive neurons project to the thalamus and investigated respo...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2014.01.060

    authors: Hayama T

    更新日期:2014-04-03 00:00:00

  • Heterogeneous dopamine receptor changes in early and late Huntington's disease.

    abstract::Quantitative receptor autoradiography was used to study dopamine (DA) receptors in dorsal striatum and its projection regions in brains from individuals dying with Huntington's disease (HD) and controls. Heterogeneous loss of both D1 and D2 receptors was present in the striatum of early and late stage HD brains. The d...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(91)90448-3

    authors: Richfield EK,O'Brien CF,Eskin T,Shoulson I

    更新日期:1991-10-28 00:00:00

  • C-type natriuretic peptide suppresses arginine-vasopressin secretion from dissociated magnocellular neurons in newborn rat supraoptic nucleus.

    abstract::Central administration of C-type natriuretic peptide (CNP) affects various neuroendocrine systems. In the present study, we examined whether CNP acts directly on arginine-vasopressin (AVP) secretion from rat supraoptic nucleus (SON) neurons, using acute dissociated cell preparations. CNP inhibited the basal secretion ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(97)00431-x

    authors: Yamamoto S,Morimoto I,Yanagihara N,Kangawa K,Inenaga K,Eto S,Yamashita H

    更新日期:1997-06-27 00:00:00

  • Nicotinamide inhibits inducible nitric oxide synthase mRNA in primary rat glial cells.

    abstract::Nitric oxide (NO) exerts cytotoxic effects on various cells including neuronal cells. Glial NO production, mediated via induction of inducible NO synthase (iNOS), enhances neurotoxicity associated with the N-methyl-D-aspartate (NMDA) receptor. The present study examined whether nicotinamide, an inhibitor of poly (ADP-...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(97)00373-x

    authors: Fujimura M,Tominaga T,Yoshimoto T

    更新日期:1997-06-06 00:00:00

  • Apolipoprotein E4 accelerates dementia and increases cerebrospinal fluid tau levels in Alzheimer's disease.

    abstract::To examine the effect of apolipoprotein E (ApoE) 4 on the progression of Alzheimer's disease (AD), the clinical course of 33 AD patients (17 cases with ApoE epsilon4 and 16 cases without ApoE epsilon4) was evaluated with the mini-mental state examination (MMSE) and cerebrospinal fluid (CSF) biological markers. The dec...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(99)00323-7

    authors: Kanai M,Shizuka M,Urakami K,Matsubara E,Harigaya Y,Okamoto K,Shoji M

    更新日期:1999-05-21 00:00:00

  • The cytotoxicity of 27-hydroxycholesterol in co-cultured SH-SY5Y cells and C6 cells.

    abstract:BACKGROUND:Diverse physiological and pathological functions of 27-hydroxycholesterol (27-OHC) were proved. However, cytotoxicity and potential influence of 27-OHC on cholesterol metabolism in neurons are unclear. DESIGN AND METHODS:In the vitro co-culture system, SH-SY5Y cells and C6 cells were applied to explore the ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2016.08.056

    authors: Wang H,Yuan L,Ma W,Han J,Lu Y,Feng L,Xiao R

    更新日期:2016-10-06 00:00:00