Abstract:
:Pain consists of sensory and negative affective components. Using a conditioned place aversion (CPA) paradigm, we investigated whether the medial thalamus (MT) played a role in the affective component of visceral pain induced by intraperitoneal injection of acetic acid into male Long-Evan rats. Acetic acid produced writhing response as well as CPA. The bilateral MT-lesions resulted in slight reduction of writhing response, but CPA was not affected. The results suggest that while MT may play a role in visceral nociception, it does not participate in the negative affective component of visceral pain.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Wang HC,Chai SC,Wu YS,Wang CCdoi
10.1016/j.neulet.2007.04.064subject
Has Abstractpub_date
2007-06-08 00:00:00pages
80-4issue
1eissn
0304-3940issn
1872-7972pii
S0304-3940(07)00530-7journal_volume
420pub_type
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