Solubilization and immunopurification of rat brain synaptic vesicle protein 2A with maintained binding properties.

abstract：:Striatal neurons containing acetylcholine and somatostatin were examined using a pharmacohistochemical procedure for acetylcholinesterase and NADPH-diaphorase histochemistry respectively. The use of these two histochemical procedures allowed both cholinergic and somatostatin cells to be visualized simultaneously in si...

journal_title：Neuroscience letters

authors： Vincent SR,Staines WA,Fibiger HC

更新日期：1983-02-21 00:00:00

abstract：:Freshly isolated or culture-expanded human umbilical cord blood mononuclear cells (CBMNCs) have been known to express neural phenotypes in vitro and to differentiate into neural cells and improve neurological function recovery after being administrated into rodent models of neurological diseases. However, the mechanis...

journal_title：Neuroscience letters

authors： Fan CG,Zhang QJ,Tang FW,Han ZB,Wang GS,Han ZC

更新日期：2005-06-03 00:00:00

abstract：:Hrk, a regulator of cell death, belongs to the family of pro-apoptotic BH3-only proteins and is known to induce apoptosis in nerve tissue. We examined Hrk gene expression to clarify the role of BH3-only proteins in apoptosis of retinal ganglion cells (RGCs) after optic nerve transection in the adult rat. Reverse trans...

journal_title：Neuroscience letters

authors： Wakabayashi T,Kosaka J,Hommura S

更新日期：2002-01-25 00:00:00

abstract：:Opiate withdrawal syndrome is temporally associated with the hyperactivity of locus coeruleus neurons. Previous studies have shown that this hyperactivity, at least in part, results from the activity of excitatory afferents which mainly include the orexinergic neurons of hypothalamus and glutamatergic neurons of parag...

journal_title：Neuroscience letters

authors： Hooshmand B,Azizi H,Javan M,Semnanian S

更新日期：2017-01-01 00:00:00

abstract：:Mammals navigate a complex environment using a variety of strategies, which can operate in parallel and even compete with one another. We have recently described a variant water maze task in which two of these strategies, hippocampus-dependent spatial learning and striatum-dependent cued learning, can be dissociated. ...

journal_title：Neuroscience letters

authors： Baldan Ramsey LC,Pittenger C

更新日期：2010-10-11 00:00:00

abstract：BACKGROUND:Down syndrome (DS) is caused by either complete or partial triplication of chromosome 21, affecting approximately 1/1000 live births, and it is widely accepted that individuals with DS are more likely to develop dementia of Alzheimer's disease (DAD) compared with the general population. Many studies have inv...

journal_title：Neuroscience letters

authors： Patel A,Rees SD,Kelly MA,Bain SC,Barnett AH,Thalitaya D,Prasher VP

更新日期：2011-01-07 00:00:00

abstract：:Neuromuscular electrical stimulation (NMES) increases the excitability of corticospinal (CS) pathways by altering circuits in motor cortex (M1). How NMES affects circuits interposed between the ascending afferent volley and descending CS pathways is not known. Presently, we hypothesized that short-latency afferent inh...

journal_title：Neuroscience letters

authors： Mang CS,Bergquist AJ,Roshko SM,Collins DF

更新日期：2012-10-31 00:00:00

abstract：:Diffusion MRI studies characterizing the changes in white matter (WM) due to vascular cognitive impairment, which includes all forms of small vessel disease are reviewed. We reviewed the usefulness of diffusion methods in discriminating the affected WM regions and its relation to cognitive impairment. These studies we...

journal_title：Neuroscience letters

authors： Raja R,Rosenberg G,Caprihan A

更新日期：2019-02-16 00:00:00

abstract：:Learning is important for humans and can be disrupted by disease. However, the essence of how learning may be represented within a neuronal network is still elusive. Spike trains generated by neurons have been demonstrated to carry information which is relevant for learning. The present study uses well-established mut...

journal_title：Neuroscience letters

authors： Jog MS,Aur D,Connolly CI

更新日期：2007-01-22 00:00:00

abstract：:The neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on striatal total biopterin were examined both in rats and mice at different time courses. Results indicate that MPTP caused a significant decrease of total biopterin content in the striatum of mice. This effect occurred as soon as 6 h after...

journal_title：Neuroscience letters

authors： Lee EH

更新日期：1988-06-07 00:00:00

abstract：:A differential localization of binding sites in the rat brain for [3H]D-Ala2,Leu5-enkephalin ([3H]DADL) and [3H]etorphine ([3H]Eto) was been demonstrated by an in vitro autoradiography technique. Labeling with [3H]DADL was found predominantly in septum and paraventricular nuclei of hypothalamus, whereas [3H]Eto labeli...

journal_title：Neuroscience letters

authors： Duka T,Schubert P,Wüster M,Stoiber R,Herz A

更新日期：1981-01-20 00:00:00

abstract：:The cognitive deficits observed in schizophrenia are considered a core feature of the disease. Neuregulin-1 is a risk gene for schizophrenia that is involved in many neurodevelopmental and synaptic plasticity-related processes relevant to schizophrenia. Here, we have utilized a rat model (Nrg1(Tn)), which is hypomorph...

journal_title：Neuroscience letters

authors： Taylor AR,Taylor SB,Koenig JI

更新日期：2012-12-07 00:00:00

abstract：:Low doses of colchicine (greater than 0.5 microgram) injected into the eyes of young chickens irreversibly inhibit axonal transport of material labelled with [3H]fucose. This is due to almost total destruction of the retinal ganglion cells, while other retinal cell types, including the displaced amacrine cells found i...

journal_title：Neuroscience letters

authors： Morgan IG

更新日期：1981-07-17 00:00:00

abstract：:Using immunohistochemistry we studied the presence of calbindin in myenteric neurones of the guinea-pig stomach. A rabbit anti recombinant rat calbindin-D28k (CALB) stained 12, 12 and 25% of all myenteric neurones in the fundus, corpus and antrum, respectively. A rabbit anti recombinant human CALB stained 4, 4 and 16%...

journal_title：Neuroscience letters

authors： Reiche D,Pfannkuche H,Michel K,Hoppe S,Schemann M

更新日期：1999-07-30 00:00:00

abstract：:The effects of acute and subacute supramaximal and submaximal electroshock-induced convulsions on rat brain tribulin activity were investigated. Both supramaximal and submaximal shocks induced a marked increase, as measured 30 min after the onset of convulsions, with a significantly greater effect from the former. The...

journal_title：Neuroscience letters

authors： Bhattacharya SK,Banerjee PK,Glover V,Sandler M

更新日期：1991-04-15 00:00:00

abstract：:Quantitative neurophysiological studies have identified the presence of at least two spinal neuron populations (ABRUPT and SUSTAINED) which are excited by the noxious visceral stimulus colorectal distension (CRD). The present study examined the effects of acute colorectal inflammation on the activity of dorsal horn ne...

journal_title：Neuroscience letters

authors： Ness TJ,Gebhart GF

更新日期：2000-03-10 00:00:00

abstract：:The effect of capsaicin was studied on non-cholinergic inhibitory postsynaptic currents (IPSC). The experiments were performed on an identified snail neurone using the single electrode voltage-clamp technique. The IPSC decayed with a bi-exponential time course. Capsaicin (200 microM) reversibly blocked both components...

journal_title：Neuroscience letters

authors： Erdélyi L,Such G

更新日期：1984-03-09 00:00:00

abstract：:Chewing and walking are two oscillatory behaviors performed on an everyday basis. The current study examined the impact chewing at different speeds (i.e. fast, slow, preferred) had on walking performance for fifteen young healthy adults (23.2 + 4.2 years) and fifteen healthy older participants (66.5 + 3.2 years). Chew...

journal_title：Neuroscience letters

authors： Samulski B,Prebor J,Armitano C,Morrison S

更新日期：2019-04-17 00:00:00

abstract：:Retrograde axonal transport and fluorescent retrograde labelling of neurons were investigated in a crustacean motor system. A fluorescent tracer (Granular blue) was injected into an antennal muscle of rock lobster in order to identify the motor neurons innervating it. After an appropriate post-injection survival time,...

journal_title：Neuroscience letters

authors： Rossi-Durand C,Sorensen KE

更新日期：1985-04-09 00:00:00

abstract：:The present study compared performance and event-related brain potentials between dyslexic subjects and control subjects while they performed a spatial selective attention-shifting task. The subjects received a prestimulus cue on each trial, which indicated whether the subjects should attend to a position to the left ...

journal_title：Neuroscience letters

authors： Wijers AA,Been PH,Romkes KS

更新日期：2005-02-10 00:00:00

abstract：:The purpose of the study was to investigate the accuracy of location of equivalent current dipoles estimated by the dipole tracing method (DT) utilizing a realistic 3-shell (scalp-skull-brain) head model (SSB-DT). Three patients with intractable complex partial seizures, diagnosed as having typical temporal seizures w...

journal_title：Neuroscience letters

authors： Homma I,Masaoka Y,Hirasawa K,Yamane F,Hori T,Okamoto Y

更新日期：2001-05-18 00:00:00

abstract：:During the early postnatal development of the rat, gamma-aminobutyric acid (GABA)-like immunoreactive axons were contained within the subcortical white matter. Some of the immunoreactive axons crossed the midline, while others followed a vertical or longitudinal trajectory within the lateral part of the corpus callosu...

journal_title：Neuroscience letters

authors： Cobas A,Alvarez-Bolado G,Fairén A

更新日期：1988-10-31 00:00:00

abstract：:The phenotypic manifestation of McArdle disease varies considerably from one individual to the next. The purpose of this study was to assess the possible association between the clinical severity of the disease, and each of the genotypes PYGM (R50X), ACE (I/D), AMPD1 (Q12X), PPARGC1A (G482S) and ACTN3 (R577X). We also...

journal_title：Neuroscience letters

authors： Rubio JC,Gómez-Gallego F,Santiago C,García-Consuegra I,Pérez M,Barriopedro MI,Andreu AL,Martín MA,Arenas J,Lucia A

更新日期：2007-07-18 00:00:00

abstract：:To determine how position sense depends on the functional state of the receptors involved, we assessed the accuracy of knee position sense before and after a moderate exercise on a cycle ergometer. Measurements were done on 32 healthy subjects with four protocols combining two tasks (intramodal: using the contralatera...

journal_title：Neuroscience letters

authors： Bouët V,Gahéry Y

更新日期：2000-08-04 00:00:00

abstract：:Studies of amino acid release were carried out using frozen sections from brains of schizophrenics and controls. Synaptosomes were prepared via differential centrifugation in Ficoll allowing the veratridine-induced release of aspartate, glutamate, glycine, and GABA to be measured. The release of glutamate and gamma-am...

journal_title：Neuroscience letters

authors： Sherman AD,Davidson AT,Baruah S,Hegwood TS,Waziri R

更新日期：1991-01-02 00:00:00

abstract：:Long-term potentiation (LTP) in the dentate gyrus was previously shown to be enhanced by nicotine, an effect dependent on both homomeric α7 and heteromeric α2β2 nicotinic acetylcholine receptors (nAChR). In our experiments, bath-applied nicotine produced no significant enhancement of LTP. The α7 nAChR silent agonist N...

journal_title：Neuroscience letters

authors： Papke RL,Peng C,Kumar A,Stokes C

更新日期：2018-06-11 00:00:00

abstract：:Prolonged exposure of hippocampal slices to L-glutamate was found to produce a biphasic effect on excitatory synaptic transmission from Schaffer collateral-commissural fibers to CA1 pyramidal neurons: an early blockade of postsynaptic responses was followed by a progressive recovery. Antagonists of N-methyl-D-aspartat...

journal_title：Neuroscience letters

authors： Krishtal OA,Smirnov SV,Osipchuk YuV

更新日期：1988-02-15 00:00:00

abstract：:Transmeatal cochlear laser (TCL) treatment has recently been proposed as a therapeutic procedure for cochlear dysfunction such as chronic cochlear tinnitus or sensorineural hearing loss. The aim of this study was to investigate whether TLC has any influence on the central nervous system using functional MRI with healt...

journal_title：Neuroscience letters

authors： Siedentopf CM,Ischebeck A,Haala IA,Mottaghy FM,Schikora D,Verius M,Koppelstaetter F,Buchberger W,Schlager A,Felber SR,Golaszewski SM

更新日期：2007-01-16 00:00:00

abstract：:The transcriptional co-activator p300 plays an important role in regulating gene expression in a number of different cell types. We have shown that wild type (WT) Presenilin 1 (PS1) stimulates the transcriptional activity ability of CREB Binding Protein (CBP), a close homolog of p300, whereas the Alzheimer's disease (...

journal_title：Neuroscience letters

authors： Francis YI,Diss JK,Kariti M,Stephanou A,Latchman DS

更新日期：2007-02-14 00:00:00

abstract：:Present study was conducted to identify the efferents mediating the vasosensory reflexes evoked by intra-arterial (i.a.) injection of Mesobuthus tamulus (BT; 1mg/kg) venom in the distal segment of femoral artery. Blood pressure (BP), electrocardiogram (ECG) and respiratory movements were recorded for 60 min after the ...

journal_title：Neuroscience letters

authors： Singh SK,Deshpande SB

更新日期：2009-10-30 00:00:00