Intraocular colchicine selectively destroys immature ganglion cells in chicken retina.

abstract：:Psychotic symptoms are common in individuals with Alzheimer's disease (AD), and define a phenotype associated with more rapid cognitive and functional decline. Evidence suggests that psychotic symptoms may be influenced by genetic factors, and recent studies in schizophrenia, bipolar affective disorder (BPAD) and Alzh...

journal_title：Neuroscience letters

authors： Sims R,Hollingworth P,Moskvina V,Dowzell K,O'Donovan MC,Powell J,Lovestone S,Brayne C,Rubinsztein D,Owen MJ,Williams J,Abraham R

更新日期：2009-09-11 00:00:00

abstract：:Dibutyrylcytidine 3',5'-cyclic monophosphate (Bt2cCMP) stimulated neurite outgrowth in rat pheochromocytoma PC12 cells in a dose-dependent manner at the dose range from 0.5 mM to 6 mM. About 25% of the cells had neurites in response to 6 mM Bt2cCMP. In contrast with the effect of nerve growth factor (NGF) which increa...

journal_title：Neuroscience letters

authors： Yanagida M,Gohda E,Yamamoto I

更新日期：1990-07-13 00:00:00

abstract：:Schisandra chinensis is commonly used for food and as a traditional remedy for the treatment of neuronal disorders. However, it is unclear which component of S. chinensis is responsible for its neuropharmacological effects. To answer this question, we isolated α-iso-cubebene, a dibenzocyclooctadiene lignin, from S. ch...

journal_title：Neuroscience letters

authors： Park SY,Park SJ,Park NJ,Joo WH,Lee SJ,Choi YW

更新日期：2013-10-25 00:00:00

abstract：:Opioid kappa-agonists had much more potent inhibitory effects on the high K+-evoked Met-enkephalin release from rat brain slices than did the mu- or delta-agonists. The opioid kappa- antagonist, MR2266 enhanced the evoked release of Met-enkephalin to a greater extent than did mu- or delta-antagonists in vitro and had ...

journal_title：Neuroscience letters

authors： Ueda H,Fukushima N,Ge M,Takagi H,Satoh M

更新日期：1987-10-29 00:00:00

abstract：:Essentially all animals with nervous systems utilize electrical synapses as a core element of communication. Electrical synapses, formed by gap junctions between neurons, provide rapid, bidirectional communication that accomplishes tasks distinct from and complementary to chemical synapses. These include coordination ...

journal_title：Neuroscience letters

authors： O'Brien J

更新日期：2019-03-16 00:00:00

abstract：:The majority of previous studies which have explored the mechanisms underlying perception of the direction of gravity in static roll tilt have proposed that the tendency to estimate the subjective visual vertical (SVV) as tilted towards body tilt ('Aubert effect') arises from an underestimation of perceived body tilt....

journal_title：Neuroscience letters

authors： Ceyte H,Cian C,Trousselard M,Barraud PA

更新日期：2009-10-02 00:00:00

abstract：:A broad spectrum caspase inhibitor reduces hypoxic ischemic brain injury. We hypothesized that a specific caspase-9 inhibitor would provide similar protection. Seven-day-old rat pups had the right carotid artery ligated, then were subjected to 2.5 h of 8% oxygen. Caspase-9 activity in the right cortex was measured enz...

journal_title：Neuroscience letters

authors： Feng Y,Fratkin JD,LeBlanc MH

更新日期：2003-07-03 00:00:00

abstract：:To identify the roles of gamma-aminobutyric acid (GABA) transporter in epileptogenesis and the recovery mechanisms in spontaneous seizure, a chronological and comparative analysis of GABA transporters (GAT) expression was conducted. GAT-1 immunoreactivity was more strongly detected in the pre-seizure group of seizure ...

journal_title：Neuroscience letters

authors： Kang TC,Kim HS,Seo MO,Park SK,Kwon HY,Kang JH,Won MH

更新日期：2001-09-07 00:00:00

abstract：:Genetic factors play an important role in Parkinson's disease (PD) and vary from different races. A previous genome-wide association study (GWAS) identified 17 novel risk loci that were associated with PD in Caucasians. Several subsequent studies investigated the association between these loci and PD in Chinese popula...

journal_title：Neuroscience letters

authors： Hu X,Mao C,Hu Z,Zhang Z,Zhang S,Yang Z,Fan Y,Fan L,Zheng H,Yang J,Liu Y,Yuan Y,Wang Y,Shi C,Xu Y

更新日期：2020-04-23 00:00:00

abstract：:Electrical stimulation of the A1 noradrenergic region of the ventrolateral medulla produced synatic excitation (n = 19, 9%), inhibition (n = 5, 2%) or no effect (n = 184, 89%) in the activity of a total of 208 neurons in the subfornical organ (SFO) in male rats under urethane anesthesia. Almost all (n = 18) of the exc...

journal_title：Neuroscience letters

authors： Tanaka J,Mashiko N,Kawakami A,Hatakenaka S,Fujisawa S,Nomura M

更新日期：2002-10-25 00:00:00

abstract：:Although the coadministration of lidocaine with propranolol interferes with the metabolic profile (pharmacokinetics), its pharmacodynamics is still unclear. In this report, we investigate whether propranolol can potentiate the effect of lidocaine. Rats received spinal anesthesia with lidocaine co-injected with propran...

journal_title：Neuroscience letters

authors： Chen YW,Chu CC,Chen YC,Hung CH,Li YT,Wang JJ

更新日期：2011-09-26 00:00:00

abstract：:l-Carnosine (β-alanyl-l-histidine), a dipeptide of the amino acids β-alanine and histidine, is found in mammalian tissues including those in the central nervous system and in skeletal muscles. In the present study, we examined the effects of intraduodenal (ID) injection of l-carnosine on splenic sympathetic nerve acti...

journal_title：Neuroscience letters

authors： Horii Y,Shen J,Fujisaki Y,Yoshida K,Nagai K

更新日期：2012-02-21 00:00:00

abstract：:The present study was designed to test the hypothesis that administration of low extracellular levels of magnesium ions ([Mg(2+)](o)) to primary cultured cerebral vascular smooth muscle cells will cause lipid peroxidation, degradation of IkappaB-alpha, and activation of nuclear transcription factor kappa B (NF-kappaB)...

journal_title：Neuroscience letters

authors： Altura BM,Gebrewold A,Zhang A,Altura BT

更新日期：2003-05-08 00:00:00

abstract：:The effects of acute and subacute supramaximal and submaximal electroshock-induced convulsions on rat brain tribulin activity were investigated. Both supramaximal and submaximal shocks induced a marked increase, as measured 30 min after the onset of convulsions, with a significantly greater effect from the former. The...

journal_title：Neuroscience letters

authors： Bhattacharya SK,Banerjee PK,Glover V,Sandler M

更新日期：1991-04-15 00:00:00

abstract：:The distribution of cholecystokinin binding sites was studied by receptor autoradiography in the human striatum at midgestation, birth and adulthood. In the adult, cholecystokinin receptors are inhomogeneously distributed with patches of reduced labeling. In the caudate nucleus but not in the putamen these patches mat...

journal_title：Neuroscience letters

authors： Schiffmann SN,Goldman S,Heyman P,De Vuyst M,De Roy G,Vanderhaeghen JJ

更新日期：1992-07-06 00:00:00

abstract：:Eukaryotic mRNA precursors are co-transcriptionally assembled into ribonucleoprotein complexes. Heterogeneous nuclear ribonucleoprotein (hnRNP) complexes are involved in mRNA translocation, stability, subcellular localization and regulation of mRNA translation. About 20 major classes of hnRNPs have been identified in ...

journal_title：Neuroscience letters

authors： Lopes GS,Lico DTP,Silva-Rocha R,de Oliveira RR,Sebollela A,Paçó-Larson ML,Larson RE

更新日期：2019-03-23 00:00:00

abstract：:The purpose of this study was to investigate how the recruitment gain, as derived from the Hoffmann (H)-reflex measurement, of antagonistic motoneurons is modulated during voluntary lengthening (LEN) and shortening (SHO) contractions in the human tibialis anterior (TA) muscle. To this end, the parameters of the ratios...

journal_title：Neuroscience letters

authors： Sekiguchi H,Nakazawa K,Akai M

更新日期：2003-05-15 00:00:00

abstract：:This study examines the ultrastructural relationships established by the nigrostriatal dopaminergic and the corticostriatal afferent fibers with neuropeptide Y (NPY)-containing neurons in the rat striatum. By means of dual immunolabeling procedures using peroxidase conjugated F(ab) fragments and 125I-labeled protein A...

journal_title：Neuroscience letters

authors： Vuillet J,Kerkerian L,Kachidian P,Bosler O,Nieoullon A

更新日期：1989-05-22 00:00:00

abstract：:Parkin Co-Regulated Gene (PACRG) is a gene that shares a bi-directional promoter with the Parkinson's disease associated gene parkin. The functional role of PACRG is not well understood, although the gene has been associated with parkinsonian syndromes and more recently with eukaryotic cilia and flagella. We investiga...

journal_title：Neuroscience letters

authors： Wilson GR,Tan JT,Brody KM,Taylor JM,Delatycki MB,Lockhart PJ

更新日期：2009-08-21 00:00:00

abstract：:We assess in mice, the electrophysiological criteria developed in humans and rats in vivo for unmyelinated (C) fibre differentiation into sub-classes, derived from the activity-induced latency increase ("slowing") in response to electrical stimulation during 6 min at 0.25 Hz followed by 3 min at 2 Hz. Fibres are consi...

journal_title：Neuroscience letters

authors： Hoffmann T,De Col R,Messlinger K,Reeh PW,Weidner C

更新日期：2015-04-10 00:00:00

abstract：:The enzyme horseradish peroxidase (HRP) has been applied to the proximal stumps of severed thoracic and lumbar dorsal roots in the turtles Pseudemys scripta elegans and Testudo hermanni. The results obtained confirm the distribution pattern observed with anterograde degeneration techniques. Primary afferent terminal s...

journal_title：Neuroscience letters

authors： Kusuma A,ten Donkelaar HJ

更新日期：1979-10-01 00:00:00

abstract：:Seizures are relatively common in the first weeks of life and can have lasting effects on brain development due to glutamate excitotoxicity. The excitatory amino acid transporter 2 (EAAT2) is responsible for the majority of glutamate uptake in the brain and mice with this gene deleted die from seizures. Therefore, we ...

journal_title：Neuroscience letters

authors： Lauriat TL,Schmeidler J,McInnes LA

更新日期：2007-01-22 00:00:00

abstract：:Nitric oxide synthase-immunoreactivity (NOS-IR) was detected in strands of nerve fibers entering the rat superior cervical ganglia (SCG) and in nerve fibers forming a plexus beneath the capsule of adrenal glands. Within the SCG, varicose NOS-IR fibers encircled virtually all postganglionic neurons and small diameter c...

journal_title：Neuroscience letters

authors： Dun NJ,Dun SL,Wu SY,Förstermann U

更新日期：1993-08-06 00:00:00

abstract：:beta-Amyloid protein immunoreactivity in neocortex and hippocampus of Alzheimer's disease and control brains has been measured using an automatic image analysis system. Successive fields from the pial surface to white matter in 4 neocortical sites, parahippocampal gyrus and along the pyramidal cell layer in the hippoc...

journal_title：Neuroscience letters

authors： Cairns NJ,Chadwick A,Luthert PJ,Lantos PL

更新日期：1991-08-05 00:00:00

abstract：:Calcium homeostasis in synaptosomes is altered during ageing. The cytosolic free calcium concentration, [Ca2+]i was determined in synaptosomes and crude synaptosomal fractions from 3- and 24-month-old rats with the fluorescent indicator quin-2. The [Ca2+]i were around two times higher in 24-month-old rats than in adul...

journal_title：Neuroscience letters

authors： Martinez A,Vitórica J,Satrústegui J

更新日期：1988-06-07 00:00:00

abstract：:We have investigated the effect of capsaicin pretreatment (50 mg kg(-1) s.c.) on substance P, preprotachykinin (PPT) mRNA, and nerve growth factor (NGF), plus its high-affinity receptor, trkA, in adult rats with adjuvant arthritis. Twenty one days after induction of adjuvant arthritis, sciatic nerve levels of substanc...

journal_title：Neuroscience letters

authors： Garrett NE,Cruwys SC,Kidd BL,Tomlinson DR

更新日期：1997-07-11 00:00:00

abstract：:Manual actions and speech are connected: for example, grip execution can influence simultaneous vocalizations and vice versa. Our previous studies show that the consonant [k] is associated with the power grip and the consonant [t] with the precision grip. Here we studied whether the interaction between speech sounds a...

journal_title：Neuroscience letters

authors： Tiainen M,Tiippana K,Paavilainen P,Vainio M,Vainio L

更新日期：2017-06-09 00:00:00

abstract：:The present study was designed to test the hypothesis that acute administration of alcohol (ethanol) to primary cultured cerebral vascular smooth muscle cells will cause lipid peroxidation, inhibition of IkappaB phosphorylation, and inhibition of nuclear transcription factor-kappa B (NF-kappaB). Ethanol (10, 25, 100 m...

journal_title：Neuroscience letters

authors： Altura BM,Gebrewold A,Zhang A,Altura BT

更新日期：2002-06-07 00:00:00

abstract：:Using a new polyclonal antibody against prostacyclin (PGI2)-synthase this enzyme was shown to be present in neuronal cells of bovine, rat and human brain, most abundantly in Purkinje cells of the cerebellum and cortical neurons, but not in glial cells. Western blots confirmed the specificity of the antibody and applie...

journal_title：Neuroscience letters

authors： Mehl M,Bidmon HJ,Hilbig H,Zilles K,Dringen R,Ullrich V

更新日期：1999-08-27 00:00:00

abstract：:Involvement of the ipsilateral hemisphere during planning of reaching movements is still matter of debate. While it has been demonstrated that the contralateral hemisphere is dominant in visuo-motor integration, involvement of the ipsilateral hemisphere has also been proposed. Furthermore, a dominant role for left pos...

journal_title：Neuroscience letters

authors： Busan P,Jarmolowska J,Semenic M,Monti F,Pelamatti G,Pizzolato G,Battaglini PP

更新日期：2009-08-28 00:00:00