The changes in the expressions of gamma-aminobutyric acid transporters in the gerbil hippocampal complex following spontaneous seizure.

abstract：:Chronic social defeat stress in mice significantly decreases subsequent social interactions and induces other depression-like behaviors. Here we measured and manipulated levels of acetylated histone H3 (acH3), a chromatin mark of transcriptional activation, in the hippocampus and amygdala after ten continuous days of ...

journal_title：Neuroscience letters

authors： Covington HE 3rd,Vialou VF,LaPlant Q,Ohnishi YN,Nestler EJ

更新日期：2011-04-15 00:00:00

abstract：:Previous research has revealed the existence of perceptual mechanisms that compensate for slight temporal asynchronies between auditory and visual signals. We investigated whether temporal recalibration would also occur between auditory and tactile stimuli. Participants were exposed to streams of brief auditory and ta...

journal_title：Neuroscience letters

authors： Navarra J,Soto-Faraco S,Spence C

更新日期：2007-02-08 00:00:00

abstract：:Parkin is a ubiquitin ligase involved in the ubiquitin-proteasome system. Elevating parkin expression in cells reduces markers of oxidative stress while blocking parkin expression increases oxidative stress. In parkin gene knock down mouse and fly models, mitochondria function is deficient. Parkin is neuroprotective a...

journal_title：Neuroscience letters

authors： Klein RL,Dayton RD,Henderson KM,Petrucelli L

更新日期：2006-06-19 00:00:00

abstract：:Patients with Parkinson's disease develop motor disturbances often accompanied by peripheral autonomic dysfunctions, including gastrointestinal disorders, such as dysphagia, gastric stasis and constipation. While the mechanisms subserving enteric autonomic dysfunctions are not clearly understood, they may involve the ...

journal_title：Neuroscience letters

authors： Blandini F,Balestra B,Levandis G,Cervio M,Greco R,Tassorelli C,Colucci M,Faniglione M,Bazzini E,Nappi G,Clavenzani P,Vigneri S,De Giorgio R,Tonini M

更新日期：2009-12-31 00:00:00

abstract：:The association between the dopamine D4 receptor (DRD4) exon III polymorphism and personality trait of novelty seeking (NS) has been studied intensively. In the Japanese population, the results of the previous studies did not always coincide. In the present study, we investigated the association between the polymorphi...

journal_title：Neuroscience letters

authors： Tochigi M,Hibino H,Otowa T,Kato C,Marui T,Ohtani T,Umekage T,Kato N,Sasaki T

更新日期：2006-05-08 00:00:00

abstract：:In this study we examined the presence of dopamine D1 receptors in monkey amniotic epithelial cells (MAEC) using RT-PCR and radioligand binding experiments. We found that MAEC express D1 receptor mRNA that is having 99% homology with human dopamine D1 receptors. Saturation binding studies using [3H]SCH-23390 showed a ...

journal_title：Neuroscience letters

authors： Elwan MA,Ishii T,Ono F,Sakuragawa N

更新日期：1999-02-26 00:00:00

abstract：:Schizophrenia has been observed to be associated with various abnormalities in cytokines and cytokine receptors. Three very recent reports showed the evidence that the IL3 gene, colony stimulating factor 2 receptor alpha (CSF2RA), beta (CSF2RB) and IL-3 receptor alpha (IL3RA), the IL-specific receptor subunits for CSF...

journal_title：Neuroscience letters

authors： Sun S,Wang F,Wei J,Cao LY,Wu GY,Lu L,Kosten TA,Kosten TR,Zhang XY

更新日期：2008-07-25 00:00:00

abstract：:Controversy exists regarding the site where anesthetics act in the brain to produce sedation and unconsciousness. Actions in the cerebral cortex and thalamus are likely, although the relative importance of each site is unclear. We used in computo modeling to investigate the sensitivity of cortical and thalamic neurons...

journal_title：Neuroscience letters

authors： Judge O,Hill S,Antognini JF

更新日期：2009-10-23 00:00:00

abstract：:APPsw transgenic mice showing substantial features of brain Abeta amyloidosis such as senile plaques and behavioral abnormalities were examined by immunostaining to determine whether Abeta deposits could induce the subsequent disturbance of neurotransmitter systems including somatostatin, substance P and choline acety...

journal_title：Neuroscience letters

authors： Tomidokoro Y,Harigaya Y,Matsubara E,Ikeda M,Kawarabayashi T,Okamoto K,Shoji M

更新日期：2000-10-13 00:00:00

abstract：:Recently, we reported that a centrally acting non-narcotic antitussive (cough suppressant drug), tipepidine produces an antidepressant-like effect in the forced swimming test in rats. Because pharmacological properties of tipepidine apparently differ from those of typical antidepressants developed to date, we speculat...

journal_title：Neuroscience letters

authors： Kawaura K,Miki R,Shima E,Honda S,Soeda F,Shirasaki T,Takahama K

更新日期：2010-09-13 00:00:00

abstract：:The critical period for observing a developmentally regulated form of synaptic plasticity in the visual cortex of young rats normally ends at about postnatal day 30. This developmentally regulated form of in vitro long-term potentiation (LTP) can be reliably induced in layers II-III by aiming high frequency, theta bur...

journal_title：Neuroscience letters

authors： Shaffery JP,Lopez J,Bissette G,Roffwarg HP

更新日期：2006-01-02 00:00:00

abstract：:We studied the extracellular concentration of glutamate and taurine in the frontal cortex of freely-moving pentylenetetrazole (PTZ) kindled rats using an in vivo microdialysis. A significant and sustained increase in the glutamate level was observed in the kindled rats, in contrast, a slight and delayed increase was o...

journal_title：Neuroscience letters

authors： Li Z,Yamamoto Y,Morimoto T,Ono J,Okada S,Yamatodani A

更新日期：2000-03-17 00:00:00

abstract：:We assess in mice, the electrophysiological criteria developed in humans and rats in vivo for unmyelinated (C) fibre differentiation into sub-classes, derived from the activity-induced latency increase ("slowing") in response to electrical stimulation during 6 min at 0.25 Hz followed by 3 min at 2 Hz. Fibres are consi...

journal_title：Neuroscience letters

authors： Hoffmann T,De Col R,Messlinger K,Reeh PW,Weidner C

更新日期：2015-04-10 00:00:00

abstract：:The mouse model of transcranial permanent occlusion of the middle cerebral artery (tpMCAO) is widely used in stroke research. Here we quantified infarct size using a conventional histological method at several post-ischaemic times, going beyond the commonly analysed period of up to 2 days, following artery occlusion. ...

journal_title：Neuroscience letters

authors： Henrich-Noack P,Baldauf K,Reiser G,Reymann KG

更新日期：2008-02-20 00:00:00

abstract：:Amino acid release in the dorsal horn of awake rats was examined by microdialysis during the development of arthritis induced by injection of 3% kaolin and 3% carrageenan into the knee joint. The following amino acids were measured by HPLC at baseline and for the first 8 h of arthritis: Asp, Glu, Asn, Gln, Ser, Gly an...

journal_title：Neuroscience letters

authors： Sluka KA,Westlund KN

更新日期：1992-10-12 00:00:00

abstract：:We have attempted to determine the effects of electroconvulsive shock (ECS) on protein phosphatase 2A (PP2A) in the frontal cortices of rats. PP2A exhibited a 30% increase in activity immediately after ECS treatment. Immunoblot analysis revealed that phosphorylation signals, including protein kinase B (Akt/PKB), glyco...

journal_title：Neuroscience letters

authors： Kang UG,Jeon WJ,Kim Y,Chung CK,Park JB,Juhnn YS,Kim YS

更新日期：2005-12-30 00:00:00

abstract：:The present study is designed to screen the effect of syringin, an active principle purified from the rhizome and root parts of Eleutherococcus senticosus (Araliaceae), on the plasma glucose and investigate the possible mechanisms. Plasma glucose decreased in a dose-dependent manner 60 min after intravenous injection ...

journal_title：Neuroscience letters

authors： Liu KY,Wu YC,Liu IM,Yu WC,Cheng JT

更新日期：2008-03-28 00:00:00

abstract：:Previous neuroimaging studies raised the hypothesis that enhanced activity in the ipsilateral motor cortex (M1) plays a contributing role in the compensation for the motor deficits resulting from a spinal cord injury (SCI). However, it is still unknown whether the activity in the ipsilateral M1 directly contributes to...

journal_title：Neuroscience letters

authors： Nardone R,Höller Y,Höller P,Thon N,Thomschewski A,Brigo F,Trinka E

更新日期：2013-09-27 00:00:00

abstract：:The electron microscopic findings in cats after complete interruption of all afferents to caudate nucleus as well as of its efferent fibers, suggest that the type IX synapses, the presynaptic component of which contains large empty round vesicles, are formed by the axon terminals of intrinsic neurons. They make synapt...

journal_title：Neuroscience letters

authors： Hassler R,Chung JW,Wagner A,Rinne U

更新日期：1977-07-01 00:00:00

abstract：:The polymerase chain reaction was utilized to determine which of six cloned phospholipase A2 (PLA2) messenger RNAs (mRNAs), encoding four distinct low molecular weight forms of secretory PLA2 (PLA2-IB, PLA2-IIA, PLA2-IIC and PLA2-V), a calcium-dependent high molecular weight PLA2 (PLA2-IV, cPLA2) and a calcium-indepen...

journal_title：Neuroscience letters

authors： Molloy GY,Rattray M,Williams RJ

更新日期：1998-12-24 00:00:00

abstract：:The present study evaluated the relationship between asymmetry of the prefrontal cortex activity and the automatic nervous system (ANS) response during a mental arithmetic (MA) task. Employing near infrared spectroscopy, we compared cerebral blood oxygenation changes in the right and left prefrontal cortices during a ...

journal_title：Neuroscience letters

authors： Tanida M,Sakatani K,Takano R,Tagai K

更新日期：2004-10-07 00:00:00

abstract：:Immunohistochemical fluorescent double labeling revealed the coexistence of galanin and substance P in nerve fibers in the mouse nasal mucosa. At the base of and in the epithelium, all galanin fibers also contained substance P, but around the blood vessels and glands, most of them did not. Since substance P fibers in ...

journal_title：Neuroscience letters

authors： Matsuda H,Tsukuda M,Kadota T,Kusunoki T,Kishida R

更新日期：1994-05-23 00:00:00

abstract：:Neurons containing the peptide corticotropin-releasing factor (CRF) are thought to play a pivotal role in orchestrating autonomic and behavioral responses to stress. CRF afferents to the thalamus are almost entirely concentrated in the midline nuclei, especially in the paraventricular thalamic nucleus. In chloral hydr...

journal_title：Neuroscience letters

authors： Otake K,Nakamura Y

更新日期：1995-12-01 00:00:00

abstract：:Methylphenidate (MPH) is a dopamine and norepinephrine reuptake inhibitor that is widely used for the treatment of attention-deficit/hyperactivity disorder in children and adults. Its similarity to other psychostimulants suggests that, at certain doses, the drug may generate lasting neuroadaptations that can be detrim...

journal_title：Neuroscience letters

authors： Taukulis HK,Bigney EE,Fry MD,Hooper C

更新日期：2014-04-30 00:00:00

abstract：:Interleukin-1 beta (IL-1 beta), interleukin-2 (IL-2), and interleukin-6 (IL-6) were measured in the cerebrospinal fluid (CSF) and plasma of 12 control subjects, 11 sporadic Alzheimer's disease (AD) and 22 de novo Parkinson's disease (PD) patients using high sensitivity enzyme-linked immunosorbent assays (ELISA). IL-1 ...

journal_title：Neuroscience letters

authors： Blum-Degen D,Müller T,Kuhn W,Gerlach M,Przuntek H,Riederer P

更新日期：1995-12-29 00:00:00

abstract：:Although rats often show an upright standing behavior the cardiovascular response during the behavior has not yet been fully clarified. In this study we quantified the activity of upright standing behavior in rats using infrared beam detectors and measured cardiovascular variables during the behavior. Rats demonstrate...

journal_title：Neuroscience letters

authors： Waki H,Katahira K,Yamasaki M,Katsuda S,Shimizu T,Maeda M

更新日期：2009-01-02 00:00:00

abstract：:As the pre-dementia phase of Alzheimer disease, mild cognitive impairment (MCI) involves the onset and development of cognitive impairments. Opioid receptors play pivotal roles in the regulation of learning and cognition. Our study focused on the association of OPRK1 and OPRM1 methylation with MCI in Xinjiang Uygur an...

journal_title：Neuroscience letters

authors： Liu G,Ji H,Liu J,Xu C,Chang L,Cui W,Ye C,Hu H,Chen Y,Zhou X,Duan S,Wang Q

更新日期：2017-01-01 00:00:00

abstract：:Cultured embryonic mouse olfactory bulb cells formed asymmetric, symmetric, axodendritic, and dendrodendritic synapses. These neurons contained electron lucent, dense core, and coated vesicles. Dense core and coated vesicles had an average diameter of 71 and 80 nm, respectively. Two statistically different populations...

journal_title：Neuroscience letters

authors： Fracek SP Jr,Guo L,Schafer R

更新日期：1994-04-11 00:00:00

abstract：:Dopamine D1 and D2 receptors were studied in putamen of post-mortem brains from controls and patients with Alzheimer-type dementia (ATD). A significant reduction in dopamine D2 receptors was observed in ATD, whereas dopamine D1 receptors were unchanged. Neurochemical markers of striatal acetylcholine and GABA-containi...

journal_title：Neuroscience letters

authors： Cross AJ,Crow TJ,Ferrier IN,Johnson JA,Markakis D

更新日期：1984-11-23 00:00:00

abstract：:The present study shows that cultured fibroblasts from sporadic Alzheimer's disease patients are deficient in protein kinase C-regulated secretion of amyloid precursor protein. In particular, Alzheimer fibroblasts show a reduced basal secretion and a reduced response at low concentrations of phorbol-12,13-dibutyrate, ...

journal_title：Neuroscience letters

authors： Bergamaschi S,Binetti G,Govoni S,Wetsel WC,Battaini F,Trabucchi M,Bianchetti A,Racchi M

更新日期：1995-12-01 00:00:00