Abstract:
:The distribution of cholecystokinin binding sites was studied by receptor autoradiography in the human striatum at midgestation, birth and adulthood. In the adult, cholecystokinin receptors are inhomogeneously distributed with patches of reduced labeling. In the caudate nucleus but not in the putamen these patches match the striosomal organization as revealed by acetylcholinesterase staining. At midgestation, patches of high density of cholecystokinin receptors are in register with the dopamine D1 receptor-enriched striosomes. At birth, this striosomal organization has already evolved into the adult pattern of higher matrix level in contrast to the striosomal pattern of acetylcholinesterase staining.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Schiffmann SN,Goldman S,Heyman P,De Vuyst M,De Roy G,Vanderhaeghen JJdoi
10.1016/0304-3940(92)90329-6keywords:
subject
Has Abstractpub_date
1992-07-06 00:00:00pages
39-42issue
1eissn
0304-3940issn
1872-7972pii
0304-3940(92)90329-6journal_volume
141pub_type
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