Abstract:
:Receptor gated Ca2+ entry has been associated with transient receptor potential (TRP) proteins encoded by several different genes. Here, we compare expression of mRNA for TRP isoforms encoded by genes TRP1-6 in the rat substantia nigra and whole brain. The substantia nigra and the whole brain expressed mRNA predominantly for TRP3 and TRP6. The levels of TRP1, 2, 4 and 5 were very low in both. The TRP6 mRNA levels in substantia nigra and the whole brain were comparable while those for TRP3 were significantly lower in substantia nigra than in the whole brain. Thus substantia nigra differs from the whole brain in its TRP expression.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Sylvester JB,Mwanjewe J,Grover AKdoi
10.1016/s0304-3940(01)01533-6keywords:
subject
Has Abstractpub_date
2001-03-09 00:00:00pages
83-6issue
2eissn
0304-3940issn
1872-7972pii
S0304394001015336journal_volume
300pub_type
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