Presynaptic opioid kappa-receptor and regulation of the release of Met-enkephalin in the rat brainstem.

abstract：:The present study was performed to explore the role of galanin in nociceptive modulation in anterior cingulate cortex (ACC) of rats with acute inflammation, and the changes in galanin and galanin receptor 2 (Gal R2) expressions in rats with acute inflammation. Intra-ACC injection of galanin induced antinociception in ...

journal_title：Neuroscience letters

authors： Zhang ML,Fu FH,Yu LC

更新日期：2017-01-18 00:00:00

abstract：:Bradykinin, an inflammatory mediator produced from plasma kallikreins, has potent effects on vascular functions, including increasing plasma extravasation and vasodilation. Attenuation in the response (desensitization to maintained exposure or tachyphylaxis to repeated administration) to bradykinin actions on synovial...

journal_title：Neuroscience letters

authors： Miao FJ,Khasar SG,Green PG,Levine JD

更新日期：1996-04-19 00:00:00

abstract：OBJECT:Much evidence has demonstrated that stress and tumor interact, but the mechanisms are poorly understood. The purpose of this study is to discuss the effect of unpredictable chronic mild stress (CMS) upon the behavior of Walker 256 tumor-bearing rats and its mechanism. METHODS:Observe the effects of CMS on the s...

journal_title：Neuroscience letters

authors： Xiu LJ,Lin HM,Wei PK

更新日期：2010-03-31 00:00:00

abstract：:Recombinant retroviruses containing the cDNA for human tyrosine hydroxylase-1 and Escherichia coli lacZ gene were used to infect primary foetal ventral mesencephalon and cortical cultures from rat brain. Severe neuronal toxicity resulted 3-4 days after infection, glial cells seemed to be much more resistant. The toxic...

journal_title：Neuroscience letters

authors： Hurley MJ,Bradford HF,O'Hare K,Stern GM,Uchida K

更新日期：1996-12-06 00:00:00

abstract：:An in vitro assay was used to determine the effects of conditioning nerve lesions on the regeneration of adult rat retinal ganglion cell (RGC) axons from retinal explants. Following the conditioning lesion (CL) of unilateral optic nerve transection, maximal regrowth was seen from RGC explanted from ipsilateral retinae...

journal_title：Neuroscience letters

authors： Johnson AR,Gregson NA,Wigley CB,Berry M

更新日期：1989-02-13 00:00:00

abstract：:Limited work has been done to investigate the molecular mechanisms behind the process of demyelination and remyelination that occurs in response to chronic nerve compression (CNC) injury. In the present study, we investigated the expression of the transcription factors krox-20 and c-jun, positive and negative regulato...

journal_title：Neuroscience letters

authors： Pham K,Nassiri N,Gupta R

更新日期：2009-11-13 00:00:00

abstract：:In this study, we investigated the eye movement and postural control performance in dyslexic children while reading text and performing Landolt reading when sitting and standing. Fifteen dyslexic and 15 non-dyslexic children were asked to sit in a chair while the eye movements were recorded, and were then asked to sta...

journal_title：Neuroscience letters

authors： Razuk M,Barela JA,Peyre H,Gerard CL,Bucci MP

更新日期：2018-11-01 00:00:00

abstract：:Highly purified and metabolically viable gamma-aminobutyric acid (GABA)ergic and cholinergic synaptosomes were prepared from mammalian brain using antisera raised against glutamate decarboxylase and choline acetyltransferase respectively. These antisera appear to recognise specific outwardly facing components of GABAe...

journal_title：Neuroscience letters

authors： Docherty M,Bradford HF,Wu JY

更新日期：1987-10-16 00:00:00

abstract：:Both the onset of and recovery from desensitization of three types of responses to acetylcholine in Aplysia californica occurred by biphasic kinetics. The fast component of onset recovered at a slower rate than the slow component of onset. The rates of onset and recovery were widely different when the three response t...

journal_title：Neuroscience letters

authors： Chesnut TJ,Carpenter DO

更新日期：1983-09-09 00:00:00

abstract：:In vitro quantitative autoradiography was used to visualize nicotinic receptors in large cryosections of human brain hemispheres. Sections 80 microns thick of human brain hemispheres were incubated with (-)-[3H]nicotine and the distribution of nicotinic receptors in human brain was studied. Increasing numbers of nicot...

journal_title：Neuroscience letters

authors： Adem A,Nordberg A,Jossan SS,Sara V,Gillberg PG

更新日期：1989-07-03 00:00:00

abstract：:Vitamin B12 is implicated in methylation processes. Myelin basic protein is methylated on one arginine group. A defect in methylation could produce an unstable protein, leading to neurological disorders. In order to study myelin basic protein, we have developed the cultures of newborn rat oligodendrocytes in vitamin B...

journal_title：Neuroscience letters

authors： Sponne IE,Gaire D,Stabler SP,Droesch S,Barbé FM,Allen RH,Lambert DA,Nicolas JP

更新日期：2000-07-21 00:00:00

abstract：:Thyrotropin releasing hormone (TRH) was applied iontophoretically to single neruones in the rat bulbar reticular formation. TRH excited 41 to 56 cells tested; none were inhibited. Excitation developed slowly and was prolonged, and desensitization often occurred. TRH effects were not correlated with effects of acetylch...

journal_title：Neuroscience letters

authors： Briggs I

更新日期：1979-11-01 00:00:00

abstract：:Acetylcholinesterase (AChE) is an essential enzymatic component of the neuromuscular junction where it is responsible for terminating neurotransmission by the cholinergic motor neurons. The enzyme at the neuromuscular junction (NMJ) is contributed primarily by the skeletal muscle where it is produced at higher levels ...

journal_title：Neuroscience letters

authors： Rotundo RL

更新日期：2020-09-14 00:00:00

abstract：:A mini-symposium (chaired by L. Chal, Australia, P. Lembeck, Austria, J. Szolcsányi, Hungary and M. Zimmermann, F.R.G.) was held in Bad Nauheim, F.R.G. on June 29, 1990, under the sponsorship of the European Neuropeptide Club, which focussed on recent advances of research on sensory peptides and mechanism of action of...

journal_title：Neuroscience letters

authors： Maggi CA,Pierau FK

更新日期：1991-01-28 00:00:00

abstract：:The effects of maternal deprivation (MD) during early postnatal life on the brain-derived neurotrophic factor (BDNF) level were investigated in the present study. Wistar rats were assigned to either maternal deprivation or mother-reared control (MRC) groups. MD manipulation was achieved by separating rat pups from the...

journal_title：Neuroscience letters

authors： Kuma H,Miki T,Matsumoto Y,Gu H,Li HP,Kusaka T,Satriotomo I,Okamoto H,Yokoyama T,Bedi KS,Onishi S,Suwaki H,Takeuchi Y

更新日期：2004-11-30 00:00:00

abstract：:Spontaneous Frequency Bursts (SFBs) are a newly discovered form of long-distance neural coordination. They have several distinctive properties, including near-simultaneity of occurrence (+/-25-50 ms) across distant brain regions and high within- and across-site coherence in multiple low and high frequency bands, presu...

journal_title：Neuroscience letters

authors： Robson J,Mehta N,Polcz JE,Hermer L

更新日期：2010-03-03 00:00:00

abstract：:The calcitonin-gene receptor peptide (alphaCGRP) receptor is present in high levels in the caudal striatum of the rat. Previous behavioural experiments have highlighted a possible correlation between alphaCGRP-mediated effects and the dopaminergic system. In this study, we examined the effect of alphaCGRP on K(+)-evok...

journal_title：Neuroscience letters

authors： Maneuf YP,McKnight AT

更新日期：2001-09-14 00:00:00

abstract：:Small iontophoretic applications of wheat germ agglutinin-conjugated to horseradish peroxidase have been used to simultaneously observe, in the rat, the afferent and efferent connections of small parabrachial subregions in the same animal. The results demonstrate that a restricted region centered on the external porti...

journal_title：Neuroscience letters

authors： Bernard JF,Peschanski M,Besson JM

更新日期：1989-05-22 00:00:00

abstract：:The opioid peptide dynorphin decreased somatic calcium-dependent action potential duration in a portion of mouse dorsal root ganglion (DRG) neurons without altering resting membrane potential or conductance. Dynorphin action was antagonized by naloxone. Responses of DRG neurons to dynorphin differed from responses to ...

journal_title：Neuroscience letters

authors： Werz MA,Macdonald RL

更新日期：1984-05-04 00:00:00

abstract：:Astrocytes in the CNS produce inflammatory mediators in response to several stimuli and cytokines. Here we investigated the in vitro effect of leptin on inducible nitric oxide synthase (iNOS) expression in a glioma cell line (C6). After hormone stimulation, culture media were analysed for accumulated stable oxidation ...

journal_title：Neuroscience letters

authors： Mattace Raso G,Esposito E,Iacono A,Pacilio M,Coppola A,Bianco G,Diano S,Di Carlo R,Meli R

更新日期：2006-03-27 00:00:00

abstract：:The periaqueductal gray (PAG) is involved in motor activities, such as movements of the neck, back and hind limbs, cardiovascular regulation, micturition, vocalization, and mating behavior, as well as in nociception control. To accomplish these functions the PAG uses information from other parts of the limbic system, ...

journal_title：Neuroscience letters

authors： Mouton LJ,VanderHorst VG,Holstege G

更新日期：1997-11-28 00:00:00

abstract：:The modification of tuning properties in the cochlea has been studied by means of tuning curves from auditory nerve fibers in kittens of various ages. Comparison of tuning curves of three characteristic frequencies (CF) shows that the tuning of high CF units tends to approach adult values by the end of the second post...

journal_title：Neuroscience letters

authors： Romand R

更新日期：1983-03-14 00:00:00

abstract：:The subventricular germinal zone (SVZ) retains an active population of stem cells and neural precursor cells throughout adulthood. EphrinB signaling mediates angiogenesis and vasculogenesis in the developing and adult brain. Recent studies indicate that molecules involved in angiogenesis often influence neurogenesis a...

journal_title：Neuroscience letters

authors： Katakowski M,Zhang Z,deCarvalho AC,Chopp M

更新日期：2005-09-16 00:00:00

abstract：:Recently we have demonstrated the presence of a gap in the avian retinotectal projection, that corresponds with the locus of retinotopic representation of the elongated optic nerve head. The present report describes an equivalent gap in the optic neuropiles of the avian ventral geniculate nucleus and griseum tectalis ...

journal_title：Neuroscience letters

authors： Puelles L,Martinez S,Martinez-de-la-Torre M

更新日期：1988-02-15 00:00:00

abstract：:Recently, researchers have developed protocols for human cerebral organoids using human pluripotent stem cells, which mimic the structure of the developing human brain. Existing research demonstrated that human cerebral organoids which undergo short cultivation periods, contain astrocytes, neurons, and neural stem cel...

journal_title：Neuroscience letters

authors： Matsui TK,Matsubayashi M,Sakaguchi YM,Hayashi RK,Zheng C,Sugie K,Hasegawa M,Nakagawa T,Mori E

更新日期：2018-03-23 00:00:00

abstract：:Intracortical facilitatory and inhibitory processes in the primary motor cortex (M1) play an important role in both the preparation and execution of motor tasks. Here we aimed to (1) confirm the existence of, and further characterise, intracortical facilitation at long conditioning-test stimulus intervals at subthresh...

journal_title：Neuroscience letters

authors： Vallence AM,Schneider LA,Pitcher JB,Ridding MC

更新日期：2014-06-06 00:00:00

abstract：:The effects of noradrenaline (NA) on synaptic responses in layer II of the entorhinal cortex (EC) were studied in normal and spontaneously epileptic mutant mice tottering using intracellular recording in a slice preparation. Neither the membrane properties of neurones nor the responses to NA differed between normal an...

journal_title：Neuroscience letters

authors： Pralong E,Magistretti PJ

更新日期：1994-09-26 00:00:00

abstract：:Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels which mediate fast cholinergic synaptic transmission in insect and vertebrate nervous systems. A point mutation Y151S had been identified in Nilaparvata lugens (brown planthopper) that is associated with target-site resistance to neonicotinoid in...

journal_title：Neuroscience letters

authors： Zhang Y,Liu S,Gu J,Song F,Yao X,Liu Z

更新日期：2008-12-03 00:00:00

abstract：:The present study was designed to address the role of macrophages in Mn-induced neurotoxicity and to test the hypothesis that minocycline, a tetracycline derivative, attenuates the biochemical and morphological sequelae of Mn. Mn was unilaterally microinjected into rat nigra followed by systemic minocycline or saline ...

journal_title：Neuroscience letters

authors： Ponzoni S

更新日期：2012-01-06 00:00:00

abstract：:Repeated or sustained exposure to opioids can not only induce analgesia but also long lasting enhancements in pain sensitivity, a phenomenon reported clinically and in animals. In rats, opioid-induced abnormal pain can be readily measured following continued delivery of morphine and the recruitment of descending facil...

journal_title：Neuroscience letters

authors： Suzuki R,Porreca F,Dickenson AH

更新日期：2006-10-23 00:00:00