Abstract：
:Spontaneous Frequency Bursts (SFBs) are a newly discovered form of long-distance neural coordination. They have several distinctive properties, including near-simultaneity of occurrence (+/-25-50 ms) across distant brain regions and high within- and across-site coherence in multiple low and high frequency bands, presumably requiring high axonal, dendritic and vascular integrity. We examined whether SFBs occurred in young and young-adult C57BK6 mice with properties similar to those seen in rats. We found that across the entorhinal and piriform cortices, SFBs occur robustly in young and young-adult mice under light anesthesia, and that their rate of occurrence dropped sharply as anesthetic levels increased, as in rats. Moreover, murine SFBs showed high cross-site coherence in multiple frequency bands, including those that require exquisite action potential timing to be maintained across long distances. We discuss our findings in light of SFBs potential as a pre-clinical biomarker for diseases affecting action potential firing and local field potential coherence, especially in high frequency ranges (20-30 Hz and beyond).
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Robson J,Mehta N,Polcz JE,Hermer Ldoi
10.1016/j.neulet.2010.01.014subject
Has Abstractpub_date
2010-03-03 00:00:00pages
74-8issue
2eissn
0304-3940issn
1872-7972pii
S0304-3940(10)00030-3journal_volume
471pub_type
杂志文章abstract：:Stroke in rodents is associated with increased neurogenesis and the migration of newborn neurons to sites of brain ischemia, where they may participate in repair and recovery. To determine if neurogenesis following stroke yields functional new neurons, we labeled neuronal precursors in the mouse subventricular zone (S...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2008.07.032
更新日期：2008-09-19 00:00:00
abstract：:The present study was designed to address the role of macrophages in Mn-induced neurotoxicity and to test the hypothesis that minocycline, a tetracycline derivative, attenuates the biochemical and morphological sequelae of Mn. Mn was unilaterally microinjected into rat nigra followed by systemic minocycline or saline ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2011.10.066
更新日期：2012-01-06 00:00:00
abstract：:Parkinson's disease (PD) is characterized by the selective loss of dopaminergic (DAergic) neurons in the substantia nigra and the subsequent depletion of dopamine (DA). This study assessed the protective effects of costunolide on DA-induced apoptosis in human DAergic SH-SY5Y cells, and its regulation of DA metabolism-...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2011.10.037
更新日期：2012-01-24 00:00:00
abstract：:Regeneration of reduced nicotinamide adenine dinucleotide phosphate (NADPH) is essential for the activity of glutathione redox cycling during cellular peroxide detoxification. In order to test for a function of astroglial glycogen to serve as endogenous precursor for glucose-6-phosphate, the substrate for the regenera...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(00)01369-0
更新日期：2000-09-01 00:00:00
abstract：:Since the rubro-olivary projection has not been demonstrated in the rat, unlike the monkey and cat (refs. in text). HRP or highly-concentrated wheat germ agglutinin-horseradish peroxidase (WGA-HRP) was injected into the inferior olivary nucleus using a ventral approach. After processing with a modified technique, sect...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(87)90307-7
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(02)00412-3
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2005.09.078
更新日期：2006-01-30 00:00:00
abstract：:We examined Na+,K(+)-ATPase activity in four regions of the gerbil cochlear lateral wall by measuring intracellular Na+ concentration ([Na+]i). The application of 1 mM ouabain and removal of external K+ caused a most striking increase in [Na+]i of the suprastrial fibrocytes, followed by the stria vascularis and the ty...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(96)12862-7
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abstract：:Electroencephalogram (EEG) data is an effective indicator to evaluate driver fatigue. The 16 channels of EEG data are collected and transformed into three bands (θ, α, and β) in the current paper. First, 12 types of energy parameters are computed based on the EEG data. Then, Grey Relational Analysis (GRA) is introduce...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2011.11.014
更新日期：2012-01-11 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2008.11.039
更新日期：2009-02-06 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(91)90139-k
更新日期：1991-04-15 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2009.06.021
更新日期：2009-09-18 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2010.04.034
更新日期：2010-06-14 00:00:00
abstract：:Somatostatin (SRIF) release from fetal rat cortical cells was stimulated by exposure to 10(-5) M N-methyl-D-aspartate (NMDA) (250 +/- 20% of basal at 96 h). A similar but much less potent effect was seen with kainate (KA) but not with quisqualate (Q) which inhibited SRIF release (KA 150 +/- 13%, Q 65 +/- 18% of basal ...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(91)90476-a
更新日期：1991-08-19 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2015.01.075
更新日期：2015-03-17 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2013.07.045
更新日期：2013-09-27 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2013.09.041
更新日期：2013-10-25 00:00:00
abstract：:Multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE) are characterized by T cell-mediated autoimmune inflammation of the central nervous system (CNS) leading to oligodendrocyte loss and demyelination accompanied by neuronal cell death. Neuronal TWIK-related acid-sensitive potass...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2008.09.038
更新日期：2008-12-03 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2017.08.043
更新日期：2017-10-17 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(96)12641-0
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(88)90532-0
更新日期：1988-02-03 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2020.135437
更新日期：2020-11-20 00:00:00
abstract：:Growth/differentiation factor-5 (GDF-5), a member of the transforming growth factor-beta (TGF-β) superfamily, has been shown to protect rat dopaminergic neurons against insult both in embryonic neuronal culture and in Parkinson's disease models. However, whether GDF-5 exerts neuroprotective effects in hippocampal neur...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2017.04.055
更新日期：2017-06-09 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(97)00759-3
更新日期：1997-10-24 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(98)00892-1
更新日期：1999-01-04 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/j.neulet.2008.09.048
更新日期：2008-12-03 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(94)90364-6
更新日期：1994-03-14 00:00:00
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journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(98)00428-5
更新日期：1998-06-26 00:00:00
abstract：:We examined the rubrospinal projection to forelimb motoneurons (Mns) in cats, in comparison with the corticospinal projection. Under pentobarbital anesthesia, intracellular recordings were made from forelimb Mns following stimulation of the red nucleus (RN) and the cerebral peduncle (CP). Single pulse stimulation of t...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/0304-3940(91)90913-e
更新日期：1991-06-10 00:00:00
abstract：:The development of supersensitivity to dopamine by striatal neurons is widely considered to be a response to interruption of dopaminergic synaptic function. However, it is not clear whether pre-existing dopaminergic innervation is in fact necessary for supersensitivity to develop. In this study, rat foetal striatal ce...
journal_title：Neuroscience letters
pub_type： 杂志文章
doi：10.1016/s0304-3940(96)12445-9
更新日期：1996-03-15 00:00:00
