A possible spino (trigemino)-ponto-amygdaloid pathway for pain.

Abstract:

:Small iontophoretic applications of wheat germ agglutinin-conjugated to horseradish peroxidase have been used to simultaneously observe, in the rat, the afferent and efferent connections of small parabrachial subregions in the same animal. The results demonstrate that a restricted region centered on the external portion of the lateral parabrachial area receives numerous afferents from the superficial laminae of the dorsal horn of the spinal cord and of the trigeminal subnucleus caudalis and sends a major projection to the nucleus centralis of the amygdala. This study suggests that the external portion of the lateral parabrachial area is a relay for messages evoked by noxious stimuli in a spino (trigemino)-ponto-amygdaloid pathway.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Bernard JF,Peschanski M,Besson JM

doi

10.1016/0304-3940(89)90664-2

subject

Has Abstract

pub_date

1989-05-22 00:00:00

pages

83-8

issue

1-3

eissn

0304-3940

issn

1872-7972

pii

0304-3940(89)90664-2

journal_volume

100

pub_type

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