Investigations of the discriminative properties of the frog's olfactory mucosa using a photoactivable odorant.

Abstract:

:The photoactivable compound phenylazide interacts reversibly with the frog's olfactory epithelium when delivered as an olfactory stimulus. Its application together with UV irradiation resulted in a differential reduction of the responses (electro-olfactogram) to several odorants. It was found that this chemical modification of the sensory membrane affected the responses in relative ratios which could be predicted from a classification of the odorants based upon independent studies of receptor cell odor sensitivity. The responses to chemicals representative of the 'aromatic group' were clearly more reduced than those to compounds of the 'camphoraceous group'. It is suggested that the olfactory discrimination mechanisms can be approached by the use of this method.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Delaleu JC,Holley A

doi

10.1016/0304-3940(83)90439-1

subject

Has Abstract

pub_date

1983-06-30 00:00:00

pages

251-6

issue

3

eissn

0304-3940

issn

1872-7972

pii

0304-3940(83)90439-1

journal_volume

37

pub_type

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