Inhibition of vitamin B12 metabolism by OH-cobalamin c-lactam in rat oligodendrocytes in culture: a model for studying neuropathy due to vitamin B12 deficiency.

abstract：:Postural sway during upright stance was analyzed in 12 patients with phobic postural vertigo (PPV) and in 12 age-matched healthy volunteers. Recordings were made under different conditions (with the eyes open or closed): when standing on a foam rubber pad with the head upright, turned 30 degrees to the right or left, ...

journal_title：Neuroscience letters

authors： Krafczyk S,Schlamp V,Dieterich M,Haberhauer P,Brandt T

更新日期：1999-01-15 00:00:00

abstract：:The CA1 region of the rat hippocampal slice generates spontaneous electrographic seizures (field bursts) when exposed to ACSF containing < or = 0.2 mM calcium. It has been proposed that, particularly during the early part of a field burst, synchronised activity in small independent aggregates of neurons results in low...

journal_title：Neuroscience letters

authors： Fox JE,Bikson M,Jefferys JG

更新日期：2007-01-10 00:00:00

abstract：:To investigate the role of Cl(-)-stimulated Mg(2+)-ATPase (Cl(-)-ATPase) in neurons, we examined the effects of ethacrynic acid (0.3 mM), which completely inhibits Cl(-)-ATPase on the intracellular Cl- concentrations of cultured rat hippocampal neurons, using Cl(-)-sensitive fluorescent probes. Ethacrynic acid and ATP...

journal_title：Neuroscience letters

authors： Inoue M,Hara M,Zeng XT,Hirose T,Ohnishi S,Yasukura T,Uriu T,Omori K,Minato A,Inagaki C

更新日期：1991-12-16 00:00:00

abstract：:The 5-HT(1A) receptor agonist 8-OH-DPAT (0.5mg/kg) enhances behavioral recovery when administered 15min after experimental traumatic brain injury (TBI). To determine if benefits are still attainable at clinically relevant times, treatment was delayed 1 and 2h post-TBI and motor/cognitive performance was compared to ea...

journal_title：Neuroscience letters

authors： Cheng JP,Aslam HA,Hoffman AN,Zafonte RD,Kline AE

更新日期：2007-04-12 00:00:00

abstract：:Basal and interferon (IFN)-induced levels of (2'-5') oligoadenylate synthetase activity were measured in astrocyte cultures from the mouse cerebral cortex, in neurone-enriched and mixed cerebellar cultures, and in two continuous neural cell lines by a radioimmunoassay procedure. All untreated cultures contained measur...

journal_title：Neuroscience letters

authors： Hirsch MR,Cailla H,Wietzerbin J,Goridis C

更新日期：1986-04-11 00:00:00

abstract：:The DNA-binding activity of nuclear factor (NF-kB) was found to be induced in the spinal cord of rats with experimental allergic encephalomyelitis (EAE), an animal model of multiple sclerosis (MS), from the onset of the disease. This activation of NF-kB persisted throughout the disease period and decreased thereafter ...

journal_title：Neuroscience letters

authors： Pahan K,Schmid M

更新日期：2000-06-16 00:00:00

abstract：:Heme oxygenase (HO-1) gene expression was studied in the brains of rats subjected to 30 min global cerebral ischemia followed by recirculation of up to 24 h. Total RNA was isolated from the cerebral cortex, striatum and hippocampus and reverse-transcribed into cDNA. cDNA was taken as template for PCR using HO-1-specif...

journal_title：Neuroscience letters

authors： Paschen W,Uto A,Djuricic B,Schmitt J

更新日期：1994-10-10 00:00:00

abstract：:Plasminogen belongs to the plasminogen activator system of cell signaling proteins and has recently been identified to bind to pathological prion protein PrPSC, but not to its normal conformer, PrPC. Plasminogen binds specifically to the urokinase-type plasminogen activator receptor (uPAR) to promote pericellular prot...

journal_title：Neuroscience letters

authors： Deininger MH,Trautmann K,Magdolen V,Luther T,Schluesener HJ,Meyermann R

更新日期：2002-05-10 00:00:00

abstract：:A hybridoma cell line secreting a monoclonal antibody against catalytic subunits of acetylcholinesterase in the electric organ of Narke japonica has been obtained by using a mouse immunized with the nerve terminal membranes prepared from the electric organ of Narke japonica. This monoclonal antibody (Nj-501) reacted w...

journal_title：Neuroscience letters

authors： Abe T,Sakai M,Saisu H

更新日期：1983-07-15 00:00:00

abstract：AIMS:To test the hypothesis that uridine 5'-triphosphate (UTP) had a protective effect on cerebral ischemia reperfusion (IR) injury in rats. METHODS:Ischemia was induced by intraluminal suture of middle cerebral artery occlusion (MCAO). UTP solution was delivered through an indwelling tail venous catheter via microinf...

journal_title：Neuroscience letters

authors： Tian ML,Zou Z,Yuan HB,Wang CC,Zhu QF,Xu HT,Gao X,Shi XY

更新日期：2009-11-06 00:00:00

abstract：:The neurotoxicity of the glutamate receptor agonists N-methyl-D-aspartate (NMDA), (+/-)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA), and kainate was quantitatively assessed in murine spinal cord and cortical cultures prepared under identical conditions. Compared with cortical neurons, spinal neuron...

journal_title：Neuroscience letters

authors： Regan RF

更新日期：1996-07-26 00:00:00

abstract：:The level of endogenous nerve growth factor (NGF) in rat sciatic nerve was determined using a highly sensitive two-site enzyme immunoassay. After crushing this nerve NGF accumulated linearly distal to the crush during the first 12 h to reach levels 13-fold higher than in the uncrushed contralateral side. In contrast, ...

journal_title：Neuroscience letters

authors： Korsching S,Thoenen H

更新日期：1983-08-19 00:00:00

abstract：:LHRH administration is reported to facilitate male sexual behavior. The aim of the present study was to investigate whether male sexual behavior is associated with the number of LHRH neurons in the forebrain in middle-aged rats. Male Long-Evans rats (18-19 months) were assigned to three groups on the basis of sexual p...

journal_title：Neuroscience letters

authors： Tsai YF,Tsai HW,Tai MY,Huang RL,Peng MT

更新日期：1997-11-21 00:00:00

abstract：:The mouse model of transcranial permanent occlusion of the middle cerebral artery (tpMCAO) is widely used in stroke research. Here we quantified infarct size using a conventional histological method at several post-ischaemic times, going beyond the commonly analysed period of up to 2 days, following artery occlusion. ...

journal_title：Neuroscience letters

authors： Henrich-Noack P,Baldauf K,Reiser G,Reymann KG

更新日期：2008-02-20 00:00:00

abstract：:gamma-Aminobutyric acid (GABA)-mediated neurotransmission from the granule cells to CA3 is transiently expressed during the first 3 weeks of age in the rat. In the adult, seizures provoke this inhibitory signaling to reappear. To gain insight into the origin of GABA in these cells, we explored the expression of both i...

journal_title：Neuroscience letters

authors： Maqueda J,Ramírez M,Lamas M,Gutiérrez R

更新日期：2003-12-15 00:00:00

abstract：:Changes in extracellular Ca2+ concentration ([Ca2+]e) evoked by transmitters and transmitter agonists, respectively, and by elevation of bath K+ concentration were recorded in isolated segmental ganglia of the leech Hirudo medicinalis using Ca(2+)-selective microelectrodes. A 1-min bath application of kainate (10 micr...

journal_title：Neuroscience letters

authors： Lohr C,Rose CR,Deitmer JW

更新日期：1996-02-16 00:00:00

abstract：:Adenosine has been implicated in the regulation of rapid eye movement sleep (REMS). In an attempt to understand the mechanism of production of adenosine in relation to REMS it was hypothesized that should it be involved in REMS, the latter's deprivation is likely to affect its synthetic machinery. Hence, male albino r...

journal_title：Neuroscience letters

authors： Thakkar M,Mallick BN

更新日期：1996-03-15 00:00:00

abstract：:The frog horizontal monocular optokinetic nystagmus (OKN) is asymmetrical, the temporal-nasal (T-N) stimulation being the sole stimulation efficient to evoke the reflex, the nasal-temporal (N-T) component being almost absent. Coil recordings showed that, in adult animals, prolonged monocular visual deprivation by unil...

journal_title：Neuroscience letters

authors： Jardon B,Bonaventure N

更新日期：1992-03-30 00:00:00

abstract：:Online shopping festivals play a significant role in consumers' purchase decision and have been the focus of much research and many marketing practices. However, research has yet to explore which product categories can promote consumer purchase intention during online shopping festivals. This study carried out a neuro...

journal_title：Neuroscience letters

authors： Shang Q,Jin J,Qiu J

更新日期：2020-01-10 00:00:00

abstract：:Recent neuroimaging studies indicate that there may be common ground for esthetic and moral judgments. However, because previous studies focused on either esthetic or moral judgments and did not compare the two directly, the issue remains open whether a common ground actually exists. We employed functional magnetic re...

journal_title：Neuroscience letters

authors： Avram M,Gutyrchik E,Bao Y,Pöppel E,Reiser M,Blautzik J

更新日期：2013-02-08 00:00:00

abstract：:The contribution of retinal and extraretinal signals to the coding of eye position in the head was studied in human subjects (Ss). Horizontal saccades were produced in darkness. For some trials, before returning gaze direction to the starting position, a visual signal briefly stimulated the foveal retina. Results show...

journal_title：Neuroscience letters

authors： Blouin J,Gauthier GM,Vercher JL

更新日期：1995-01-09 00:00:00

abstract：:Spontaneous action potentials were recorded longitudinally for 4-7 weeks from dissociated rat occipital cortex cells cultured on planar multi-electrode plates, during their development from isolated neurons into synaptically connected neuronal networks. Activity typically consisted of generalized bursts lasting up to ...

journal_title：Neuroscience letters

authors： Van Pelt J,Corner MA,Wolters PS,Rutten WL,Ramakers GJ

更新日期：2004-05-06 00:00:00

abstract：:Using in vivo voltammetric detection of nitric oxide (NO) a previous study demonstrated an increased NO release at the lumbar dorsal horn level of the spinal cord by peripheral inflammatory processes in decerebrated-spinalized rats. This study concerns the effects of acute peripheral stimulations. Gentle non-noxious o...

journal_title：Neuroscience letters

authors： Rivot JP,Montagne-Clavel J,Besson JM

更新日期：2002-03-01 00:00:00

abstract：:The effects of geomagnetic disturbances on urinary excretion of the melatonin metabolite, 6-hydroxymelatonin sulfate (6-OHMS), were studied in conjunction with 60 Hz magnetic field (MF) and ambient light exposure in 132 electric utility workers. Geomagnetic activity was assessed using a local (equivalent amplitude or ...

journal_title：Neuroscience letters

authors： Burch JB,Reif JS,Yost MG

更新日期：1999-05-14 00:00:00

abstract：:The pituitary-adrenal responsiveness to a mild stressor was assessed in rats that were deprived of paradoxical sleep (PS) and in controls that were not deprived. Animals were either individually- or group-deprived for 96 h and hormone levels were assessed at 0, 5, 20 or 60 min after a saline injection+novelty and comp...

journal_title：Neuroscience letters

authors： Suchecki D,Tiba PA,Tufik S

更新日期：2002-03-01 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) and insulin promote the survival of 6-7 day old post-natal rat cerebellar granule cells. Previous studies using the PI3 kinase inhibitor, wortmannin and the over-expression of protein kinase B (PKB) have indicated that both PI3 kinase and PKB activation are central for insulin-...

journal_title：Neuroscience letters

authors： Foulstone EJ,Tavaré JM,Gunn-Moore FJ

更新日期：1999-04-02 00:00:00

abstract：:Methyl-CpG binding protein 2 (MECP2) is a chromosome-binding protein that regulates the development and maintenance of brain circuits. Altered function of the protein product of MECP2 plays an important role in the etiology of many neurodevelopmental disorders. Mutations involving a loss of function are implicated in ...

journal_title：Neuroscience letters

authors： Tropea D,Mortimer N,Bellini S,Molinos I,Sanfeliu A,Shovlin S,McAllister D,Gill M,Mitchell K,Corvin A

更新日期：2016-05-16 00:00:00

abstract：:Adult monkeys who have been under training over a long period of time show a loss of the M2 component in their biceps electromyographic response to brief, random perturbations of an alternating arm movement, the M1 component being apparently enhanced. These changes of the stretch-induced responses indicate a long-term...

journal_title：Neuroscience letters

authors： Christakos CN,Wolf H,Meyer-Lohmann J

更新日期：1983-11-11 00:00:00

abstract：:The effect of 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX), a specific non-N-methyl-D-aspartate (non-NMDA) receptor antagonist, on NMDA-independent epileptiform activity induced by Mg2(+)-free medium was studied in rat basolateral amygdala (BLA) neurons using intracellular recording techniques. Twenty to 30 min after s...

journal_title：Neuroscience letters

authors： Gean PW

更新日期：1990-10-30 00:00:00

abstract：:A peptide consisting of residues 25-35 of the amyloid beta protein was applied to single neurons while monitoring membrane current by whole cell voltage clamp recording. Within minutes of direct exposure of a neuron to the amyloid beta peptide, a paroxysmal increase in neuronal membrane conductance was observed. This ...

journal_title：Neuroscience letters

authors： Simmons MA,Schneider CR

更新日期：1993-02-19 00:00:00