Neural toxicity of retroviruses.

abstract：:Unilateral transtympanic administration of the sodium channel blocker tetrodotoxin (75 microl of 3 mM TTX in 0.1 M citrate buffer, pH 5.0) produced behavioral symptoms indicative of unilateral vestibular disruption. Following survival times of 2 and 24 h immunocytochemistry for Fos revealed asymmetric labeling in the ...

journal_title：Neuroscience letters

authors： Saxon DW

更新日期：2003-03-13 00:00:00

abstract：:We studied axonal branching of 14 parabrachial nucleus neurons, activated antidromically from 2 of the 3 stimulation sites, i.e. the ipsi- and contralateral thalamic taste area (TTAs) and the ipsilateral central nucleus of the amygdala (CA). Making use of antidromic latencies, collision times and refractory periods at...

journal_title：Neuroscience letters

authors： Hayama T,Ogawa H

更新日期：1987-12-16 00:00:00

abstract：:Aluminum and zinc are two important trace elements in an organism. Although several studies have demonstrated their impacts on the intelligence, very little was known about their effects on the integrity of blood-brain barrier (BBB). To study the effects of aluminum and zinc on the permeability of BBB, different doses...

journal_title：Neuroscience letters

authors： Song Y,Xue Y,Liu X,Wang P,Liu L

更新日期：2008-11-07 00:00:00

abstract：:This study used ERPs to determine whether older adults use prosody in resolving early and late closure ambiguities comparably to young adults. Participants made off-line acceptability judgments on well-formed sentences or those containing prosody-syntax mismatches. Behaviorally, both groups identified mismatches, but ...

journal_title：Neuroscience letters

authors： Steinhauer K,Abada SH,Pauker E,Itzhak I,Baum SR

更新日期：2010-03-19 00:00:00

abstract：:The dopaminergic system has been proposed to be one of the innervations in controlling the mammalian pineal gland function. The dopamine receptors have been characterized in the pineal and the biphasic effects of dopamine on melatonin production have been demonstrated. Recently, the site of dopamine transporter (DAT),...

journal_title：Neuroscience letters

authors： Phansuwan-Pujito P,Boontem P,Chetsawang B,Ebadi M,Govitrapong P

更新日期：2006-07-31 00:00:00

abstract：:Remembering contextual aspects of an event (recollection) is an important function subserved by episodic memory. It has recently been shown that the electrophysiological correlates of recollection differ depending upon the type of information subjects retrieve from episodic memory. In the current study, we investigate...

journal_title：Neuroscience letters

authors： Peters J,Daum I

更新日期：2009-05-01 00:00:00

abstract：:The effect of the adenosine (ADO) analogue 2-chloroadenosine (CADO) on frequency-induced long-term potentiation (LTP) of the responses evoked by stimulation of the Schaffer fibres and recorded in CA1 area was studied in hippocampal slices of the rat. CADP significantly decreased LTP of the population spikes (PS) (EC50...

journal_title：Neuroscience letters

authors： de Mendonça A,Ribeiro JA

更新日期：1990-10-02 00:00:00

abstract：:Expression levels of amyloid beta (Abeta)-degrading enzymes, insulin degrading enzyme (IDE) and neprilysin (NEP), were examined in transgenic mice with Alzheimer's disease-like neuropathology. After the development of first Abeta plaques in transgenic mice brain, cortical mRNA and protein levels of IDE were significan...

journal_title：Neuroscience letters

authors： Vepsäläinen S,Hiltunen M,Helisalmi S,Wang J,van Groen T,Tanila H,Soininen H

更新日期：2008-06-20 00:00:00

abstract：:The survival of identified retinal ganglion cells (RGGs) in vitro increased when they were plated over subcultured monolayers of astrocytes. Immunofluorescence labelling of these monolayers showed that over 85% of the cells were glial fibrillary acidic protein (GFAP) positive and consisted of large, flat immature astr...

journal_title：Neuroscience letters

authors： McCaffery CA,Raju TR,Bennett MR

更新日期：1985-06-24 00:00:00

abstract：BACKROUND:8-hydroxy-2 deoxyguanosine (8-OHdG) and the 8-hydroxyguanosine (8-OHG) are the most widely used biomarkers of nucleoside oxidation affecting DNA and RNA and are considered reliable markers of oxidative stress. Increased levels of these markers are found in the various biological fluids of patients with neurod...

journal_title：Neuroscience letters

authors： Gmitterová K,Gawinecka J,Heinemann U,Valkovič P,Zerr I

更新日期：2018-01-01 00:00:00

abstract：:By a double-labeling method combining the retrograde tracing of horseradish peroxidase and the immunocytochemical technique, serotonin-, substance P- or leucine-enkephalin-like immunoreactive neurons in the midbrain periaqueductal gray (PAG) and the nucleus raphe dorsalis (DR) of the rat were found to send projection ...

journal_title：Neuroscience letters

authors： Li YQ,Jia HG,Rao ZR,Shi JW

更新日期：1990-11-27 00:00:00

abstract：:Neurodegenerative disorders such as Parkinson's disease (PD) and dementia with Lewy bodies (DLB) are characterized by impairment of autophagy. Cellular survival is dependent on efficient clearance of phosphorylated α-synuclein, which accumulates as fibrils in the neuronal cytoplasm as Lewy bodies (LBs). The forkhead b...

journal_title：Neuroscience letters

authors： Miki Y,Tanji K,Mori F,Utsumi J,Sasaki H,Kakita A,Takahashi H,Wakabayashi K

更新日期：2018-09-25 00:00:00

abstract：:Although Streptococcus pneumoniae is the major cause of meningitis, how it causes disease is poorly understood. The C-type lectin SIGN-R1 mediates the recently described SIGN-R1 complement activation pathway, which operates against capsular polysaccharides (CPSs) of S. pneumoniae in splenic marginal macrophages. Here,...

journal_title：Neuroscience letters

authors： Park JY,Choi HJ,Prabagar MG,Choi WS,Kim SJ,Cheong C,Park CG,Chin CY,Kang YS

更新日期：2009-02-06 00:00:00

abstract：:In anorexia nervosa patients, body image distortion is a core and often persistent symptom, which continues to pose a risk for relapse even after weight recovery. Using functional magnetic resonance imaging (fMRI) in combination with a computer-based life image distortion technique, we stimulated female anorectic pati...

journal_title：Neuroscience letters

authors： Seeger G,Braus DF,Ruf M,Goldberger U,Schmidt MH

更新日期：2002-06-21 00:00:00

abstract：:The localization of serotonin and non-serotonin-containing cell bodies in the interpeduncular nucleus of the rat that project to the hippocampal formation was studied using the technique of retrograde tracing of Granular Blue and immunohistochemistry on the same sections. The results indicate that the caudal magnocell...

journal_title：Neuroscience letters

authors： Groenewegen HJ,Steinbusch HW

更新日期：1984-09-28 00:00:00

abstract：:Histamine H3 receptors (H3Rs) co-localize with dopamine (DA) D1 receptors (D1Rs) on striatal medium spiny neurons and functionally antagonize D1R-mediated responses. The intra-striatal administration of D1R agonists reduces DA release whereas D1R antagonists have the opposite effect. In this work, a microdialysis meth...

journal_title：Neuroscience letters

authors： Alfaro-Rodriguez A,Alonso-Spilsbury M,Arch-Tirado E,Gonzalez-Pina R,Arias-Montaño JA,Bueno-Nava A

更新日期：2013-09-27 00:00:00

abstract：:Almost all mechanoreceptive neurons in the cortical taste area (CTA) of the rat had receptive fields (RFs) in the oral cavity, except for a few neurons at the border with the primary somatosensory area that had RFs on the contralateral rhinarium or upper lip. About one-third of the mechanoreceptive neurons with RFs in...

journal_title：Neuroscience letters

authors： Ogawa H,Wang XD

更新日期：2002-04-05 00:00:00

abstract：:The neuromuscular junction (NMJ) is the vehicle for fast, reliable and robust communication between motor neuron and muscle. The unparalleled accessibility of this synapse to morphological, electrophysiological and genetic analysis has yielded an in depth understanding of many molecular components mediating its format...

journal_title：Neuroscience letters

authors： Fish LA,Fallon JR

更新日期：2020-07-13 00:00:00

abstract：:Tyrosine phosphorylation is an important means for regulating post-ischemic signal transduction. In this article, brain ischemia was induced by four-vessel occlusion, and the effect of ischemia/reperfusion on proline-rich tyrosine kinase 2 (Pyk2) was studied. Tyrosine phosphorylation of Pyk2 in Sprague-Dawley rat hipp...

journal_title：Neuroscience letters

authors： Liu Y,Zhang GY,Hou XY,Xu TL

更新日期：2003-09-18 00:00:00

abstract：:Self-initiated leg movement in standing humans is preceded by a medio-lateral preparatory balance adjustment (PBA); however, such preparatory balance control is often absent in reflex-like stepping responses evoked by whole-body instability. The presence or absence of the PBA may reflect a task-dependent modulation of...

journal_title：Neuroscience letters

authors： McIlroy WE,Bent LR,Potvin JR,Brooke JD,Maki BE

更新日期：1999-06-04 00:00:00

abstract：:We have previously shown that 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine (H7), an inhibitor of protein kinase C, inhibits proliferation of neuroblastoma cells in culture. We have now tested whether the effect of H7 is mediated by MAP kinase and Raf. It is shown that, in Neuro 2a cells, activation of protein kinase...

journal_title：Neuroscience letters

authors： Cabedo H,Felipo V,Miñana MD,Grisolía S

更新日期：1996-08-16 00:00:00

abstract：:Brain content of leucine-enkephalin and methionine-enkephalin changes independently during kindling of the amygdala. Both peptides were measured after 4, 8, 15 and 21 days of stimulation. Leu-enkephalin showed a progressive increase during the kindling: the results on the 4th day did not differ significantly from the ...

journal_title：Neuroscience letters

authors： Vindrola O,Briones R,Asai M,Fernández-Guardiola A

更新日期：1981-10-23 00:00:00

abstract：:The phenotypic manifestation of McArdle disease varies considerably from one individual to the next. The purpose of this study was to assess the possible association between the clinical severity of the disease, and each of the genotypes PYGM (R50X), ACE (I/D), AMPD1 (Q12X), PPARGC1A (G482S) and ACTN3 (R577X). We also...

journal_title：Neuroscience letters

authors： Rubio JC,Gómez-Gallego F,Santiago C,García-Consuegra I,Pérez M,Barriopedro MI,Andreu AL,Martín MA,Arenas J,Lucia A

更新日期：2007-07-18 00:00:00

abstract：:Alterations of Ca2+ homeostasis have been reported for both fibroblasts and T-lymphocytes of patients with Alzheimer's disease (AD). Considering the importance of K+ conductances for the cellular Ca2+ regulation and the recently reported absence of a K+ channel in Alzheimer fibroblasts, we investigated K+ currents in ...

journal_title：Neuroscience letters

authors： Cohen CD,Vollmayr B,Aldenhoff JB

更新日期：1996-01-05 00:00:00

abstract：:The present investigation describes for the first time leg lateral abduction performance during long-term microgravity exposure. Two astronauts took part in the experiments, starting 2 weeks into the mission and lasting for 5 months. Results on joint angles kinematics confirm previous investigations on parabolic fligh...

journal_title：Neuroscience letters

authors： Pedrocchi A,Baroni G,Mouchnino L,Ferrigno G,Pedotti A,Massion J

更新日期：2002-02-22 00:00:00

abstract：:Songbirds and humans use auditory feedback to acquire and maintain their vocalizations. The Bengalese finch (Lonchura striata domestica) is a songbird species that rapidly modifies its vocal output to adhere to an internal song memory. In this species, the left side of the bipartite vocal organ is specialized for prod...

journal_title：Neuroscience letters

authors： Urbano CM,Peterson JR,Cooper BG

更新日期：2013-02-08 00:00:00

abstract：:Presenilin1 (PSEN1) 1143T and G384A mutations give rise to severe early-onset Alzheimer's disease in two extensively studied Belgian families. In the present study, we examined the effect of PSEN1 1143T and G384A mutations on tau phosphorylation in human SH-SY5Y and mouse Neuro-2a neuroblastoma cell lines that were tr...

journal_title：Neuroscience letters

authors： Julliams A,Vanderhoeven I,Kuhn S,Van Broeckhoven C,De Jonghe C

更新日期：1999-07-09 00:00:00

abstract：:People with Down syndrome develop Alzheimer's disease with an early age of onset. Plasma amyloid beta (Abeta) levels were measured in individuals with Down syndrome who were over the age of 40. No associations between age and Abeta1-40 and Abeta1-42 concentrations were found and nor were Abeta1-40 and Abeta1-42 levels...

journal_title：Neuroscience letters

authors： Jones EL,Hanney M,Francis PT,Ballard CG

更新日期：2009-02-20 00:00:00

abstract：:Human subjects maintained isometric plantar or dorsal flexions of the ankle in a matching task. H-reflexes of different sizes were superimposed on the steady activity. The peak-to-peak amplitude of the reflexes was measured on the electromyogram (EMG) of the soleus muscle. The size of the corresponding muscle contract...

journal_title：Neuroscience letters

authors： Ruegg DG,Fluri M

更新日期：1989-08-28 00:00:00

abstract：:Effects of sleep deprivation (SD) on one-trial recognition memory were investigated in rats using either a spontaneous novel-object or object-place recognition test. Rats were allowed to explore a field in which two identical objects were presented. After a delay period, they were placed again in the same field in whi...

journal_title：Neuroscience letters

authors： Ishikawa H,Yamada K,Pavlides C,Ichitani Y

更新日期：2014-09-19 00:00:00