Body image distortion reveals amygdala activation in patients with anorexia nervosa -- a functional magnetic resonance imaging study.

Abstract:

:In anorexia nervosa patients, body image distortion is a core and often persistent symptom, which continues to pose a risk for relapse even after weight recovery. Using functional magnetic resonance imaging (fMRI) in combination with a computer-based life image distortion technique, we stimulated female anorectic patients and healthy controls with digital pictures of their own body image, individually distorted by themselves. In anorectic patients, stimulation with their own body image was associated with activation in the right amygdala, the right gyrus fusiformis and the brainstem region. Our preliminary findings indicate an activation of the brain's 'fear network' and underscore the need for examination of body image distortions in anorectic patients with a fMRI design to further evaluate the course of this disturbance in a longitudinal approach.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Seeger G,Braus DF,Ruf M,Goldberger U,Schmidt MH

doi

10.1016/s0304-3940(02)00312-9

keywords:

subject

Has Abstract

pub_date

2002-06-21 00:00:00

pages

25-8

issue

1

eissn

0304-3940

issn

1872-7972

pii

S0304394002003129

journal_volume

326

pub_type

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