The many functions of nerve growth factor: multiple actions on nociceptors.

abstract：:Neurones immunoreactive to an antibody against a pigment-dispersing hormone (PDH-ir) are considered to be pacemaker cells in the neuronal circadian system of flies. We investigated the ultrastructure of PDH-ir varicosities, possible releasing sites of the PDH-like peptide, in the distal medulla of the optic lobe and i...

journal_title：Neuroscience letters

authors： Miskiewicz K,Pyza E,Schürmann FW

更新日期：2004-06-03 00:00:00

abstract：:Individual activation of nicotinic acetylcholine receptor (nAChR) or nitric oxide (NO) synthase in the dorsal facial area (DFA) increases blood flow of common carotid artery (CCA) supplying intra- and extra-cranial tissues. We investigated whether the activation of nAChR initiated the activation of NO synthase and gua...

journal_title：Neuroscience letters

authors： Gong CL,Leung YM,Huang YP,Lin NN,Hung YW,Lee TJ,Kuo JS

更新日期：2010-12-17 00:00:00

abstract：:Peptide histidine-isoleucine (PHI) immunoreactivity was located in amacrine-like cells in adult rat retina by use of immunohistochemical techniques. Immunoreactive somata were found in the proximal part of the inner nuclear layer. From these somata, processes could be followed into the inner plexiform layer. The termi...

journal_title：Neuroscience letters

authors： Mikkelsen JD,Larsen JN,Fahrenkrug J,Møller M

更新日期：1987-08-31 00:00:00

abstract：:Epigallocatechin-3-gallate (EGCG) is a powerful antioxidant with suggested neuroprotective action. This study investigated the protective effects of EGCG against retinal ganglion cells (RGCs) degeneration in an animal model of glaucoma. C57BL/6J mice (n=54) were divided randomly into four groups: normal control group ...

journal_title：Neuroscience letters

authors： Shen C,Chen L,Jiang L,Lai TY

更新日期：2015-07-23 00:00:00

abstract：:The pigment of human substantia nigra, neuromelanin, has been thought to be derived from dopamine. To examine the genesis of neuromelanin, we advanced a new hypothesis that neuromelanin is formed by oxidation of dopamine and cysteinyldopamine. On the basis of this hypothesis, synthetic neuromelanins were obtained by t...

journal_title：Neuroscience letters

authors： Wakamatsu K,Ito S,Nagatsu T

更新日期：1991-09-30 00:00:00

abstract：:Ample evidence has been reported to show a probable contribution of orexin in the central cardiovascular regulation. Although cardiovascular and respiratory centers in the brain are located close to each other and are interconnected, the possible participation of orexin in respiratory regulation has not been fully doc...

journal_title：Neuroscience letters

authors： Zhang W,Fukuda Y,Kuwaki T

更新日期：2005-09-09 00:00:00

abstract：:This study investigated the protective effects and mechanisms of crocin, an extract of saffron, on brain damage after traumatic brain injury (TBI) in mice. C57BL/6 mice were subjected to controlled cortical impact (CCI)-induced TBI. Pretreatment with crocin (20mg/kg) had protective effects against TBI, demonstrated by...

journal_title：Neuroscience letters

authors： Wang K,Zhang L,Rao W,Su N,Hui H,Wang L,Peng C,Tu Y,Zhang S,Fei Z

更新日期：2015-03-30 00:00:00

abstract：:In the adult, the dickkopf family member Dickkopf-like1 (Dkkl1) has been described as a testicular protein involved in the regulation of spermatocyte apoptosis. However, microarray studies additionally suggested that Dkkl1 regulation is involved in various tumors including high grade gliomas. Since investigations of D...

journal_title：Neuroscience letters

authors： Sibbe M,Jarowyj J

更新日期：2013-02-22 00:00:00

abstract：:A prevailing hypothesis is that neurogenesis is reduced in depression and that the common mechanism for antidepressant treatments is to increase it in adult hippocampus. Reduced neurogenesis has been shown in healthy rats exposed to stress, but it has not yet been demonstrated in depressed patients. Emerging studies n...

journal_title：Neuroscience letters

authors： Petersén A,Wörtwein G,Gruber SH,El-Khoury A,Mathé AA

更新日期：2009-02-20 00:00:00

abstract：:Traumatic injury to the central nervous system (CNS) results in the breakdown of the blood-brain barrier and recruitment of hematogenous cells at the site of injury. The role of chemokines in this process has been well recognized and they have been regarded as promising targets for development of anti-inflammatory the...

journal_title：Neuroscience letters

authors： Ghirnikar RS,Lee YL,Li JD,Eng LF

更新日期：1998-05-08 00:00:00

abstract：:Stress is a major risk factor in drug addiction development and relapse. Virtually all drugs of abuse act by increasing extracellular dopamine levels in the striatum. To gain an understanding of the interaction between stress and drug exposure, we studied the effects of concomitant chronic nicotine and chronic stress ...

journal_title：Neuroscience letters

authors： Salas R,De Biasi M

更新日期：2008-07-25 00:00:00

abstract：:We have examined the morphology and distribution of nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-diaphorase) cells in the retina of the guinea pig. Two morphologically distinct classes of labelled cells were detected, one with larger, darkly labelled somata commonly located in the inner nuclear layer ...

journal_title：Neuroscience letters

authors： Cobcroft M,Vaccaro T,Mitrofanis J

更新日期：1989-08-14 00:00:00

abstract：:Activities of motor units of human tibialis anterior muscle were studied when the subject maintained the force of the muscle at a constant level voluntarily. Motor units were classified into two main groups according to their discharge frequencies and their tensions. Those units which were recruited from the beginning...

journal_title：Neuroscience letters

authors： Kato M,Murakami S,Takahashi K,Hirayama H

更新日期：1981-09-01 00:00:00

abstract：:Adjacent serial sections of the organum vasculosum laminal terminalis (OVLT) of the rat were incubated with antisera of luteinizing-hormone--releasing-hormone (LH-RH) and somatostatin and stained by the peroxidase-antiperoxidase technique. The distribution patterns of the two oligopeptides show distinct differences, a...

journal_title：Neuroscience letters

authors： Krause R

更新日期：1979-02-01 00:00:00

abstract：:Neovascularization of the dissociated central nervous tissue transplanted into the lateral ventricle of the rat was studied using laminin immunohistochemistry. A very high immunoreactive response to laminin was demonstrated in the presumably newly formed vessels within the transplants and the graft-host borders. The g...

journal_title：Neuroscience letters

authors： Shigematsu K,Kamo H,Akiguchi I,Kameyama M,Kimura H

更新日期：1989-04-24 00:00:00

abstract：:The slow Wallerian degeneration protein (WldS), a fusion protein containing amino-terminal E4B and full-length nicotinamide mononucleotide adenylyltransferase 1 (Nmnat1), delays axon degeneration caused by physical damages, toxins and genetic mutations which result in patients being diagnosed with neurodegenerative di...

journal_title：Neuroscience letters

authors： Watanabe M,Tsukiyama T,Hatakeyama S

更新日期：2007-01-16 00:00:00

abstract：:In chick brain microvessels, monoamine oxidase activity using catecholamines (dopamine and noradrenaline) and indoleamines (serotonin and tryptamine) as substrates was higher than that measured in synaptosomes and free mitochondria. In contrast, phenylalkyamines such as tyramine and 2-phenylethylamine were more deamin...

journal_title：Neuroscience letters

authors： Durand M

更新日期：1986-12-12 00:00:00

abstract：:The distribution and origin of axon terminals containing nitric oxide synthase (NOS) were examined in the nucleus of the solitary tract (NST) of the rat by NADPH diaphorase histochemistry combined with nodose ganglionectomy. Axon terminals with NADPH diaphorase activity were densely distributed in the middle and cauda...

journal_title：Neuroscience letters

authors： Lü Y,Ding YQ,Qin BZ,Li JS

更新日期：1994-04-25 00:00:00

abstract：:Previous in vivo studies have indicated that both arginine vasopressin (AVP) and angiotensin II (ANG II) can modulate the baroreflex by acting on the area postrema (AP). In the present study, effects of AVP and ANG II on AP neuronal activity were investigated by recording extracellular activity in a rabbit brainstem s...

journal_title：Neuroscience letters

authors： Cai Y,Bishop VS

更新日期：1995-05-05 00:00:00

abstract：:gamma-Aminobutyric acidA (GABA(A)) gated chloride ion channels were expressed from human recombinant cDNA using the baculovirus/Sf-9 insect cell expression system. The electrophysiological effects in whole-cell currents of 5-(4-piperidyl) isoxazol-3-ol (4-PIOL), a GABA(A) receptor partial agonist, were investigated on...

journal_title：Neuroscience letters

authors： Westh-Hansen SE,Noguchi K,Witt MR,Murai Y,Nielsen M,Akaike N

更新日期：1997-07-11 00:00:00

abstract：:beta-N-Oxalylamino-L-alanine (BOAA) and beta-N-methylamino-L-alanine (BMAA) were tested for their ability to produce acute excitotoxicity in in embryonic chick retina. gamma-Aminobutyric acid (GABA) release and histology were monitored in retina treated with various concentrations of BOAA, BMAA, kainate (KA), N-methyl...

journal_title：Neuroscience letters

authors： Zeevalk GD,Nicklas WJ

更新日期：1989-07-31 00:00:00

abstract：:AMPA receptor (AMPAR) trafficking has emerged as a fundamental concept for understanding mechanisms of learning and memory as well as many neurological disorders. Classical conditioning is a simple and highly conserved form of associative learning. Our studies use an ex vivo brainstem preparation in which to study cel...

journal_title：Neuroscience letters

authors： Keifer J,Tiwari NK,Buse L,Zheng Z

更新日期：2017-04-03 00:00:00

abstract：:It is known that maternal deprivation induces hippocampal damage in the developing brains. In the present study, we examined the effects of melatonin on maternal deprivation-induced hippocampal damage both during and after stress-hyporesponsive period (SHRP). Hippocampal damage was examined by cresyl violet staining a...

journal_title：Neuroscience letters

authors： Tugyan K,Uysal N,Ozdemir D,Sonmez U,Pekcetin C,Erbil G,Sonmez A

更新日期：2006-05-01 00:00:00

abstract：:The death of neurons after brain ischaemia may be associated with activation of cyclin-dependent kinases (CDKs) and upregulation of cyclins, reflecting aberrant entry of neurons into the cell cycle. Little has been published on the expression of cell cycle proteins after brain ischaemia in man. Well-characterized anti...

journal_title：Neuroscience letters

authors： Love S

更新日期：2003-12-15 00:00:00

abstract：:Although a linear correlation between oscillatory activities in the right and left motor cortices during movements has been shown in monkeys, there has been a debate whether scalp-recorded EEG coherence in human reflects a similar association. By applying partial coherence analysis, we demonstrated that interhemispher...

journal_title：Neuroscience letters

authors： Mima T,Matsuoka T,Hallett M

更新日期：2000-06-23 00:00:00

abstract：:A characteristic of Parkinson's disease (PD) is the development of tremor within the 4-6Hz range. One method used to better understand pathological tremor is to compare the responses to tremor-type actions generated intentionally in healthy adults. This study was designed to investigate the similarities and difference...

journal_title：Neuroscience letters

authors： Morrison S,Cortes N,Newell KM,Silburn PA,Kerr G

更新日期：2013-02-08 00:00:00

abstract：:The present study was designed to test the hypothesis that alpha-tocopherol (Vit. E) and pyrrolidine dithiocarbamate (PDTC) might exert direct effects on alcohol-induced contractions of canine basilar cerebral arteries. After precontraction of arterial ring segments with ethanol, PDTC (10(-8)-10(-6) M) and Vit. E (10(...

journal_title：Neuroscience letters

authors： Li W,Zheng T,Altura BT,Altura BM

更新日期：2001-03-30 00:00:00

abstract：OBJECTIVE:Quantitative assessments of extracellular EEG to identify specific features of three main phases of seizure acquisition based on kindling model in Rat. METHODS:Male rats were divided into 2 groups including kindled (n=10) and sham (n=7) and respectively underwent an amygdala rapid kindling and placebo kindli...

journal_title：Neuroscience letters

authors： Jalilifar M,Yadollahpour A,Moazedi AA,Ghotbeddin Z

更新日期：2017-08-24 00:00:00

abstract：:The goal of the present study was to explore the relation between speed-accuracy trade-off phenomena and action kinematics in the case of pointing under isometric conditions. Increasing task difficulty resulted in a linear increase in movement time (as predicted by Fitts' law) and in systematic changes in the spatio-t...

journal_title：Neuroscience letters

authors： Billon M,Bootsma RJ,Mottet D

更新日期：2000-05-26 00:00:00

abstract：:The study examined whether the generation of the forward propulsive force (PF) during gait initiation resulted mainly from the electromyogram activity of stance ankle plantar flexor muscles (APF) which 'push' on the ground as is generally claimed in the literature. Six unilateral above-knee amputees performed a specif...

journal_title：Neuroscience letters

authors： Michel V,Do MC

更新日期：2002-06-07 00:00:00