Expression and localization of the Parkin co-regulated gene in mouse CNS suggests a role in ependymal cilia function.

abstract：:Pain threshold and pain tolerance of heat noxious stimuli were assessed to determine whether they are equivalent when measured at three equidistant sites of both volar forearms. Heat pain threshold and tolerance were measured in 18 healthy volunteers using a standard stimulation device consisting of a thermode. Pain t...

journal_title：Neuroscience letters

authors： Schaffner N,Wittwer A,Kut E,Folkers G,Benninger DH,Candia V

更新日期：2008-08-08 00:00:00

abstract：:The present study was undertaken to determine whether the postsynaptic inhibition of motoneurons that occurs following the pontine microinjection of carbachol in the decerebrate cat is due to the activity of Renshaw cells. Thirty-two out of 37 Renshaw cells (86%) were spontaneously active prior to the administration o...

journal_title：Neuroscience letters

authors： Morales FR,Engelhardt JK,Pereda AE,Yamuy J,Chase MH

更新日期：1988-04-12 00:00:00

abstract：:Psychotic symptoms are common in individuals with Alzheimer's disease (AD), and define a phenotype associated with more rapid cognitive and functional decline. Evidence suggests that psychotic symptoms may be influenced by genetic factors, and recent studies in schizophrenia, bipolar affective disorder (BPAD) and Alzh...

journal_title：Neuroscience letters

authors： Sims R,Hollingworth P,Moskvina V,Dowzell K,O'Donovan MC,Powell J,Lovestone S,Brayne C,Rubinsztein D,Owen MJ,Williams J,Abraham R

更新日期：2009-09-11 00:00:00

abstract：:Tourette syndrome/chronic tic phenotype (TS-CTD) is a neurological disorder manifested particularly by motor and vocal tics and associated with a variety of behavioral abnormalities. Recently, the mitochondrial ribosomal protein L3 gene (MRPL3) S75N, the DnaJ (Hsp40) homolog subfamily C member 13 gene (DNAJC13) A2057S...

journal_title：Neuroscience letters

authors： Guo Y,Deng X,Zhang J,Su L,Xu H,Luo Z,Deng H

更新日期：2012-05-23 00:00:00

abstract：:By studying the binding of [3H]glycine and [3H]glutamate to rat synaptic membranes in the presence of 2-amino-5-phosphonovalerate (APV) and kynurenate (KYN) we have demonstrated that KYN is more potent than APV in displacing [3H]glycine, while an opposite order of potency was seen in displacing [3H]glutamate. Moreover...

journal_title：Neuroscience letters

authors： Danysz W,Fadda E,Wroblewski JT,Costa E

更新日期：1989-01-30 00:00:00

abstract：:Behavioural sensitization to a single morphine exposure has been considered to be a long-term form of behavioural plasticity associated with opioid addiction. Accumulated evidence has shown that histone modification plays a key role in behavioural plasticity. Therefore, this study was designed to investigate whether t...

journal_title：Neuroscience letters

authors： Jing L,Luo J,Zhang M,Qin WJ,Li YL,Liu Q,Wang YT,Lawrence AJ,Liang JH

更新日期：2011-04-25 00:00:00

abstract：:Although corticotropin-releasing factor (CRF) is thought to act as a neurotransmitter to activate the locus coeruleus (LC) during hypotensive stress, the consequences of LC activation by CRF are unknown. In the present study a hypotensive challenge that activated rat LC neurons also produced cortical electroencephalog...

journal_title：Neuroscience letters

authors： Page ME,Berridge CW,Foote SL,Valentino RJ

更新日期：1993-12-24 00:00:00

abstract：:The present study investigates the effect of cognitive reappraisal on emotion regulation in socially anxious individuals. Twenty-eight female subjects were divided into high-socially anxious (HSA) and low-socially anxious (LSA) groups. All subjects viewed threatening faces under cognitive reappraisal and passive viewi...

journal_title：Neuroscience letters

authors： Yuan L,Zhou R,Hu S

更新日期：2014-08-08 00:00:00

abstract：:This work explores the hypothesis that perturbations caused by ethanol on the regulatory role of retinoids in brain development may be a mechanism involved in the neuropathology of fetal alcohol syndrome. The interaction of ethanol and retinoic acid (RA) on RA receptor (RAR) beta and glial fibrillary acidic protein (G...

journal_title：Neuroscience letters

authors： Grummer MA,Salih ZN,Zachman RD

更新日期：2000-11-17 00:00:00

abstract：:In the real world, some of the auditory and visual information received by the human brain are temporally asynchronous. How is such information integrated in cognitive processing in the brain? In this paper, we aimed to study the semantic integration of differently asynchronous audio-visual information in cognitive pr...

journal_title：Neuroscience letters

authors： Liu B,Wu G,Wang Z,Ji X

更新日期：2011-07-01 00:00:00

abstract：:Although Streptococcus pneumoniae is the major cause of meningitis, how it causes disease is poorly understood. The C-type lectin SIGN-R1 mediates the recently described SIGN-R1 complement activation pathway, which operates against capsular polysaccharides (CPSs) of S. pneumoniae in splenic marginal macrophages. Here,...

journal_title：Neuroscience letters

authors： Park JY,Choi HJ,Prabagar MG,Choi WS,Kim SJ,Cheong C,Park CG,Chin CY,Kang YS

更新日期：2009-02-06 00:00:00

abstract：:The ability of three nitric oxide (NO) donor compounds to modify ligand binding to kainate receptors was studied in tissue from human adult autopsy brains. Binding of [3H]kainic acid (5 nM) was measured in frontal cortex membranes made from Brodmann area 8 (BA 8) and autoradiographically using sections of frontal cort...

journal_title：Neuroscience letters

authors： Lees RD,Slater P,D'Souza SW

更新日期：1997-09-19 00:00:00

abstract：:Studies have demonstrated the changes of the physiological characteristics of nucleus accumbens (NAc) neurons with the postnatal development of rats. In the present study, spontaneous excitatory postsynaptic currents (sEPSCs) were recorded in the slices of NAc shell (NAcS) of adult and juvenile rats. Our results demon...

journal_title：Neuroscience letters

authors： Liu XD,Liu Z,Kong QY,Zhang JJ,Wang Y,Yu LC

更新日期：2011-06-01 00:00:00

abstract：:The conversion of cellular prion protein (PrP(C)) to its protease-resistant isoform is involved in the pathogenesis of prion disease. Although PrP(C) is a ubiquitous glycoprotein that is present in various cell types, the physiological role of PrP(C) remains obscure. The present study aimed to determine whether PrP(C)...

journal_title：Neuroscience letters

authors： Watanabe T,Yasutaka Y,Nishioku T,Kusakabe S,Futagami K,Yamauchi A,Kataoka Y

更新日期：2011-06-01 00:00:00

abstract：:A dimeric form of acetylcholinesterase from the electric organ of Torpedo californica was solubilized by phosphatidylinositol-specific phospholipase C from Staphylococcus aureus. The solubilized enzyme had a sedimentation coefficient of 7.3S which was not modified by detergents. The high salt-soluble asymmetric forms ...

journal_title：Neuroscience letters

authors： Futerman AH,Low MG,Silman I

更新日期：1983-09-19 00:00:00

abstract：:The ubiquitin carboxy-terminal hydrolase L1gene (UCH-L1) has been implicated in the aetiology of Parkinson's disease (PD). A rare Ile93Met mutation in UCH-L1 in a German PD sib-pair has been reported. Recently, a S18Y (C54A) polymorphism in exon 3 of UCH-L1 was found to be under-represented in PD patients compared to ...

journal_title：Neuroscience letters

authors： Mellick GD,Silburn PA

更新日期：2000-10-27 00:00:00

abstract：:We combined fluorescent tracing with immunohistochemistry to examine nitric oxide synthase (NOS) containing neurons in the rat ventral lateral geniculate nucleus (vLGN). NOS immunopositive neurons in vLGN had a similar appearance to previously described NADPH-d positive neurons. The majority (96%) of the NOS immunopos...

journal_title：Neuroscience letters

authors： Meng XW,Ohara PT,Ralston HJ 3rd

更新日期：1998-11-06 00:00:00

abstract：:Peripheral motor nerves have revealed variability in excitability by hyperpolarizing current at specific target response levels, likely reflecting differences in the hyperpolarization-activated current (Ih). Whether such variability in Ih exists in sensory axons is yet to be established. We performed nerve excitabilit...

journal_title：Neuroscience letters

authors： Nodera H,Rutkove SB

更新日期：2012-06-19 00:00:00

abstract：:Antioxidants may delay or prevent neural diseases. Depletion of the non-enzymatic antioxidant, glutathione, in a mouse model was produced by inhibiting its rate-limiting enzyme, gamma-glutamylcysteine synthetase, for 7 weeks. Ileum and colon were obtained from treated and control (saline) mice. Glutathione levels and ...

journal_title：Neuroscience letters

authors： Koch TR,Fink JG,Ruan E,Petro A,Opara EC

更新日期：1997-10-10 00:00:00

abstract：:Secondary optic projections were studied in the toad, Bufo marinus using the method of transneuronal transport of triated proline and fucose. Following a survival of 14 days after eye injection autoradiographic label was transported transneuronally to the contralateral nucleus isthmi, the deeper layers of the contrala...

journal_title：Neuroscience letters

authors： Mayner L

更新日期：1980-03-01 00:00:00

abstract：:To examine postural stability of the head, slow, undetectable rotations of small amplitude were imposed about a vertical axis while human subjects maintained a stationary body. Six normal subjects were used. The rotations were imposed through an elastic linkage, and lasted 4 s. The amplitude of head rotation was small...

journal_title：Neuroscience letters

authors： Chan R,Rogers DK,McCloskey DI

更新日期：1996-08-23 00:00:00

abstract：:To test the hypothesis that the expression of specific proteins on peripheral terminals of primary afferents can be attenuated by intrathecal administration of antisense oligodeoxynucleotides (ODNs), we administered ODNs antisense to the mu-opioid receptor to male Sprague-Dawley rats via chronically implanted intrathe...

journal_title：Neuroscience letters

authors： Khasar SG,Gold MS,Dastmalchi S,Levine JD

更新日期：1996-10-25 00:00:00

abstract：:Bath-applied N-methyl-D,L-aspartate (NMA) was found to elicit locomotor electromyogram (EMG) activity in ankle flexor and extensor muscles in an in vitro lumbar cord-hindlimb preparation of the newborn rat. The frequency and burst duration of the NMA-induced rhythmic EMG activity varied in a dose-dependent manner. The...

journal_title：Neuroscience letters

authors： Kudo N,Yamada T

更新日期：1987-03-20 00:00:00

abstract：:We have examined the morphology and distribution of nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-diaphorase) cells in the retina of the guinea pig. Two morphologically distinct classes of labelled cells were detected, one with larger, darkly labelled somata commonly located in the inner nuclear layer ...

journal_title：Neuroscience letters

authors： Cobcroft M,Vaccaro T,Mitrofanis J

更新日期：1989-08-14 00:00:00

abstract：:We compared, for a number of ligands to the two receptors, the displacement of [3H]strychnine binding to the glycine-gated chloride channel of spinal cord and brainstem synaptic membranes to the displacement of [3H]glycine binding to the NMDA receptor complex of hippocampal and cortex synaptic membranes. Glycine and b...

journal_title：Neuroscience letters

authors： Pullan LM,Powel RJ

更新日期：1992-12-14 00:00:00

abstract：:The effect of different frequencies of music on brain function was investigated through measurement of blood pressure in spontaneously hypertensive rats (SHR). Previous studies indicated that exposure to Mozart's music (K. 205) leads to increased calcium/calmodulin-dependent dopamine synthesis in the brain, and that t...

journal_title：Neuroscience letters

authors： Akiyama K,Sutoo D

更新日期：2011-01-03 00:00:00

abstract：:Crayfish muscle fibres were voltage-clamped at E = -80 mV membrane potential and superfused for about 10 min with Li+ saline (Na+ replaced by Li+) which contained picrotoxin to block inhibitory post-synaptic currents. Addition of veratridine (100 mumol/l) caused intense fluctuations in the voltage clamp current within...

journal_title：Neuroscience letters

authors： Finger W,Martin C

更新日期：1987-12-16 00:00:00

abstract：:The CHRNA7 gene encoding the α7 nicotinic acetylcholine receptor (nAChR) has repeatedly been linked with schizophrenia and the P50 sensory gating deficit. The α7 nAChR is considered a promising drug target for treatment of cognitive dysfunction in schizophrenia and improves memory and executive functions in patients a...

journal_title：Neuroscience letters

authors： Dyrvig M,Mikkelsen JD,Lichota J

更新日期：2019-06-21 00:00:00

abstract：:Repeated stimulation can lead to a decrement in the amplitude of a response, or its disappearance. This is known as habituation. Responses recorded in the reticular formation of the brain to peripherally applied stimuli tend to habituate. Decerebration considerably reduces the occurrence of this habituation and naloxo...

journal_title：Neuroscience letters

authors： Boxer MI

更新日期：1983-09-19 00:00:00

abstract：:Alterations of 'peripheral-type' benzodiazepine receptors (PTBRs) in brain are a feature of hepatic encephalopathy (HE). Although ammonia toxicity has been implicated in the disorder, recent findings suggest an accumulation of manganese in the brains of cirrhotic patients dying in hepatic coma. In this study, we exami...

journal_title：Neuroscience letters

authors： Hazell AS,Desjardins P,Butterworth RF

更新日期：1999-08-13 00:00:00