Effect of retinoic acid and ethanol on retinoic acid receptor beta and glial fibrillary acidic protein mRNA expression in human astrocytoma cells.

abstract：:Both chronic pain and depression are debilitating diseases, which often coexist in clinic. However, current analgesics and antidepressants exhibit limited efficacy for this comorbidity. The present study aimed to investigate the effect of ketamine on the comorbidity of inflammatory pain and consequent depression-like ...

journal_title：Neuroscience letters

authors： Zhang GF,Wang J,Han JF,Guo J,Xie ZM,Pan W,Yang JJ,Sun KJ

更新日期：2016-09-19 00:00:00

abstract：:Human nerve growth factor (NGF) serum concentrations were measured in a healthy sample of 126 participants by a modified highly sensitive and specific two-site enzyme immunoassay. The measured NGF concentrations differ considerably from a normal distribution. The median NGF concentration was 19.68 pg/ml with an interq...

journal_title：Neuroscience letters

authors： Lang UE,Gallinat J,Danker-Hopfe H,Bajbouj M,Hellweg R

更新日期：2003-06-19 00:00:00

abstract：:Neurofibromatosis 1 (NF1) is a common autosomal dominant disorder in which affected individuals develop benign and malignant tumors as well as non-tumor-related abnormalities, such as seizures and learning disabilities. Here, we report an NF1 isoform arising from the alternative splicing of exon 9a with predominant ce...

journal_title：Neuroscience letters

authors： Geist RT,Gutmann DH

更新日期：1996-06-21 00:00:00

abstract：:The effects of geomagnetic disturbances on urinary excretion of the melatonin metabolite, 6-hydroxymelatonin sulfate (6-OHMS), were studied in conjunction with 60 Hz magnetic field (MF) and ambient light exposure in 132 electric utility workers. Geomagnetic activity was assessed using a local (equivalent amplitude or ...

journal_title：Neuroscience letters

authors： Burch JB,Reif JS,Yost MG

更新日期：1999-05-14 00:00:00

abstract：:Methamphetamine (METH) has been a worldwide health threat for years. Recent studies have reported that circular RNA (circRNA) are highly abundant and dynamically expressed in brain. However, connections between circRNA and METH-induced neurotoxicity remains indefinite. In the present study, primary cortical neurons we...

journal_title：Neuroscience letters

authors： Li J,Shi Q,Wang Q,Tan X,Pang K,Liu X,Zhu S,Xi K,Zhang J,Gao Q,Hu Y,Sun J

更新日期：2019-05-14 00:00:00

abstract：:Several studies have indicated that higher levels of childhood aerobic fitness is associated with superior cognitive function, and this association is disproportionately observed in tasks requiring greater top-down control. We designed the current study to clarify the relationship between childhood fitness and top-dow...

journal_title：Neuroscience letters

authors： Kamijo K,Takeda Y,Takai Y,Haramura M

更新日期：2016-10-06 00:00:00

abstract：:Neuropathic pain (NP) is highly disabling, responds poorly to pharmacological treatment, and represents a significant cause of decreased quality of life in patients suffering from spinal cord injury (SCI). In recent years, cell therapy with autologous mesenchymal stromal cells (MSCs) has been considered as a potential...

journal_title：Neuroscience letters

authors： Vaquero J,Zurita M,Rico MA,Aguayo C,Fernández C,Gutiérrez R,Rodríguez-Boto G,Saab A,Hassan R,Ortega C

更新日期：2018-03-23 00:00:00

abstract：:A previous study of brain activation in normal subjects during a phonological (Phonemes) task and a lexical semantic (Words) task using positron-emission tomography [3] is complemented by new data after a method for image realignment was applied [17]. The pattern of cerebral blood flow increases associated with Words ...

journal_title：Neuroscience letters

authors： Démonet JF,Price C,Wise R,Frackowiak RS

更新日期：1994-11-21 00:00:00

abstract：:A remarkable candidate gene for late-onset Alzheimer's disease (AD) is 24-dehydrocholesterol reductase (DHCR24) gene that encodes seladin-1 (selective AD indicator), an enzyme that is involved in the cholesterol biosynthetic pathway, exerts neuroprotective and anti-apoptotic effects, and found to be down regulated in ...

journal_title：Neuroscience letters

authors： Fehér A,Juhász A,Pákáski M,Kálmán J,Janka Z

更新日期：2012-09-20 00:00:00

abstract：:A statistical approach to reveal the quantal behaviour of postsynaptic potentials (PSPs) is described. This includes: (1) obtaining the Fourier line spectrum (decomposition into harmonics) of the PSP histogram; and (2) testing the null hypothesis, 'the spectrum is that of white noise', using an ANOVA. The harmonic tha...

journal_title：Neuroscience letters

authors： Rusakov DA

更新日期：1993-12-12 00:00:00

abstract：:Superoxide dismutase 1 (SOD1) aggregates are a histological and biochemical correlate of disease progression in neural tissues from mutant SOD1-linked forms of familial amyotrophic lateral sclerosis (FALS). In the present study, we assayed the monomeric and high molecular weight mutant SOD1 content of nervous, muscle ...

journal_title：Neuroscience letters

authors： Turner BJ,Lopes EC,Cheema SS

更新日期：2003-10-23 00:00:00

abstract：:Fluorescent tracers (Nuclear Yellow, True Blue, Fast Blue) were injected, in various combinations, into the globus pallidus and substantia nigra in three marmosets. Examination of perikarya in the ipsilateral neostriatum, well removed from pallidal injection sites, revealed that the predominant pattern was of single-l...

journal_title：Neuroscience letters

authors： Féger J,Crossman AR

更新日期：1984-08-24 00:00:00

abstract：:Oxidative stress is considered important for the pathogenesis of Alzheimer disease (AD), which is characterized by the formation of senile plaques rich in amyloid beta-protein (Abeta). Abeta cytotoxicity has been found dependent on lysosomes, which are abundant in AD neurons and are shown to partially co-localize with...

journal_title：Neuroscience letters

authors： Zheng L,Roberg K,Jerhammar F,Marcusson J,Terman A

更新日期：2006-02-20 00:00:00

abstract：:The mammalian Period1 gene is rhythmically expressed and its proteins are found within the nucleus of the cells of the suprachiasmatic nuclei (SCN), the central circadian pacemaker in mammals; however, whether the target of the PER1 proteins is also the nucleus in the retinal peripheral clock cells is yet to be determ...

journal_title：Neuroscience letters

authors： García-Fernández JM,Alvarez-López C,Cernuda-Cernuda R

更新日期：2007-05-23 00:00:00

abstract：:The insular cortex has emerged as a novel target for nicotine addiction research. One unresolved question about the insular cortex is whether its neurons exhibit nicotine-induced dendritic remodeling similar to other brain regions implicated in nicotine addiction. To test this question, Long-Evans rats were administer...

journal_title：Neuroscience letters

authors： Ehlinger DG,Bergstrom HC,McDonald CG,Smith RF

更新日期：2012-05-10 00:00:00

abstract：:The possible voltage-dependence of the dopamine transporter (DAT) was investigated using electrophysiological and electrochemical recordings in rat brain slices containing the substantia nigra (SN). Whole-cell patch clamp recordings of DA neurons, revealed that addition of 15 mM KCl rapidly depolarized the membrane po...

journal_title：Neuroscience letters

authors： Hoffman AF,Zahniser NR,Lupica CR,Gerhardt GA

更新日期：1999-01-29 00:00:00

abstract：:Protein kinase G (PKG) has been implicated in a variety of physiological functions including synaptic plasticity in the brain. This study investigated the involvement of dopamine D3 (D3) receptors in PKG-regulated dopamine release, long-term changes in gene expression and behavioral sensitization after repeated cocain...

journal_title：Neuroscience letters

authors： Lee DK,Oh JH,Yang JH,Youn B,Shim YB,Shim I,Wang JQ,Choe ES

更新日期：2013-04-29 00:00:00

abstract：:Diazoxide is a putative mitochondrial, ATP-sensitive potassium channel opener that has been implicated in neuroprotection in cerebral ischemia. Administered as pretreatment, diazoxide can attenuate ischemia-related neuronal injury, but little is known about the potential neuroprotective properties of the drug when it ...

journal_title：Neuroscience letters

authors： Farkas E,Timmer NM,Domoki F,Mihály A,Luiten PG,Bari F

更新日期：2005-10-28 00:00:00

abstract：:The MgATP-dependent priming step of exocytosis has been suggested to be regulated negatively by GTP-binding protein G0 in permeabilized adrenal chromaffin cells. We have reported that synaptosomal-associated protein of 25 kDa (SNAP-25) and vesicle-associated membrane protein 2 (VAMP-2) form a complex in chromaffin cel...

journal_title：Neuroscience letters

authors： Misonou H,Ohara-Imaizumi M,Kumakura K

更新日期：1997-09-05 00:00:00

abstract：:Extracellular field-potential recordings and measurements of the extracellular concentration of potassium ([K+]o) were made in layers II and III of the adult rat entorhinal cortex in a slice preparation. Two types of spontaneous, synchronous potentials were induced by the convulsant drug 4-aminopyridine (4AP, 50 micro...

journal_title：Neuroscience letters

authors： Lücke A,Nagao T,Köhling R,Avoli M

更新日期：1995-02-13 00:00:00

abstract：:The acute reactions of vasoactive intestinal polypeptide (VIP)-containing neurons in the myenteric plexus of the rat jejunum in response to circumferential clamping or transection/reanastomosis were evaluated in a detailed time course of up to ten days. Whereas in sham-operated controls VIP immunostaining was confined...

journal_title：Neuroscience letters

authors： Trudrung P,Waldner H,Sklarek J,Nitsch C

更新日期：1990-02-16 00:00:00

abstract：:The relation between phantom limb pain (PLP) and the movement representation of a phantom limb remains controversial in several areas of neurorehabilitation, although there are a few studies in which the representation of phantom limb movement was precisely evaluated. We evaluated the structured movement representatio...

journal_title：Neuroscience letters

authors： Osumi M,Sumitani M,Wake N,Sano Y,Ichinose A,Kumagaya S,Kuniyoshi Y,Morioka S

更新日期：2015-09-25 00:00:00

abstract：:Inattention and impulsivity are the two most important indices for evaluations of ADHD. Currently, inattention and impulsivity were evaluated by clinical scales. The intelligent evaluation of the two indices using machine learning remains largely unexplored. This paper aimed to build regression modes for inattention a...

journal_title：Neuroscience letters

authors： Wang XH,Xu J,Li L

更新日期：2020-04-17 00:00:00

abstract：:Abnormal neural activity generated at a site of nerve injury is thought to contribute to the development of dysaesthesia. Vanilloid receptor 1 (TRPV1), a transducer of noxious stimuli, may be involved in the initiation of this abnormal activity and could provide a useful therapeutic target. We investigated the effect ...

journal_title：Neuroscience letters

authors： Biggs JE,Yates JM,Loescher AR,Clayton NM,Robinson PP,Boissonade FM

更新日期：2008-09-26 00:00:00

abstract：:The objective of the present study was to characterize the trkB receptor immunoreactive (-ir) cells in the intermediolateral cell column (IML) of the upper thoracic spinal cord. Small trkB-ir cells (area=56.1+/-4.4 microm(2)) observed in the IML showed characteristics of oligodendrocytes and were frequently observed i...

journal_title：Neuroscience letters

authors： McCartney AM,Abejuela VL,Isaacson LG

更新日期：2008-08-01 00:00:00

abstract：:The role of nitric oxide in cerebral insults remains controversial. While numerous studies have used models of ischaemia and hypoxia, few have examined nitric oxide in the kainate model of excitotoxicity. Kainate (10 mg/kg) was administered to rats via the intraperitoneal (i.p.) route to induce submaximal damage to th...

journal_title：Neuroscience letters

authors： Jones PA,Smith RA,Stone TW

更新日期：1998-06-19 00:00:00

abstract：:The present study evaluated the performance of a tracking task during which no, a small (subliminal: 20°) or a large (conscious: 60°) rotational perturbation was implemented. The instantaneous as well as carry-over effects of the perturbations were assessed. The subjective reports revealed that the subjects did not di...

journal_title：Neuroscience letters

authors： Serrien DJ,Spapé MM

更新日期：2011-04-25 00:00:00

abstract：:Neural circuitry comprising the ventral tegmental area, nucleus accumbens (NAc), prefrontal cortex (PFC) and hippocampus (HIP) has a main role in reward phenomena. Previous behavioral studies indicated that intracerebroventricular administration of AP5 (NMDA glutamate receptor antagonist) and CNQX (AMPA/kainate glutam...

journal_title：Neuroscience letters

authors： Siahposht-Khachaki A,Ezzatpanah S,Razavi Y,Haghparast A

更新日期：2018-01-01 00:00:00

abstract：:The role of nitric oxide (NO) in N-methyl-D-aspartate (NMDA)-regulated release of 5-hydroxytryptamine (5-HT) in the frontal cortex and raphe nuclei of freely moving rats has been studied using microdialysis with dual probes, one in each region of the same animal. In order to do this the selective neuronal nitric oxide...

journal_title：Neuroscience letters

authors： Smith JC,Whitton PS

更新日期：2000-09-08 00:00:00

abstract：:Neuronal nAChRs are pentameric transmembrane proteins which function as ligand-gated ion channels and are composed of multiple alpha and beta subunits. Nine neuronal nAChR alpha subunit genes (alpha2-alpha10) and three nAChR beta subunit genes (beta2-beta4) have been identified. nAChR subtypes are heteromers, composed...

journal_title：Neuroscience letters

authors： Danthi S,Boyd RT

更新日期：2006-05-29 00:00:00