Nerve growth factor serum concentrations in healthy human volunteers: physiological variance and stability.

abstract：:The chronic administration of phencyclidine-HCl (PCP-HCl), 10 mg/kg, for 6-7 days resulted in a significant increase in the striatal methionine-enkephalin level, although acute administration induced no change of methionine-enkephalin level in this area. The methionine-enkephalin levels in other areas investigated, i....

journal_title：Neuroscience letters

authors： Nabeshima T,Hiramatsu M,Amano M,Furukawa H,Kameyama T

更新日期：1983-05-27 00:00:00

abstract：:The effects of acute and subacute supramaximal and submaximal electroshock-induced convulsions on rat brain tribulin activity were investigated. Both supramaximal and submaximal shocks induced a marked increase, as measured 30 min after the onset of convulsions, with a significantly greater effect from the former. The...

journal_title：Neuroscience letters

authors： Bhattacharya SK,Banerjee PK,Glover V,Sandler M

更新日期：1991-04-15 00:00:00

abstract：:Bilaterally symmetrical periventricular lesions at preoptic-anterior hypothalamic levels of anteroventral third ventricle (AV3V) produce adipsia without aphagia in the rat. Sweet palatable fluids, but not water, are drunk during the adipsic period and if hydration is thus maintained, voluntary ingestion of plain water...

journal_title：Neuroscience letters

authors： Buggy J,Johnson AK

更新日期：1977-07-01 00:00:00

abstract：:The subcommissural organ (SCO) is a glandular circumventricular organ secreting glycoproteins into the cerebrospinal fluid. The SCO of 15-week-old spontaneously hypertensive rats (SHR) and of matched normotensive Wistar-Kyoto rats (WKY) was studied immunocytochemically by using an antibody against the glycoproteins se...

journal_title：Neuroscience letters

authors： Castañeyra-Perdomo A,Carmona-Calero E,Meyer G,Pérez-González H,Pérez-Delgado MM,Marrero-Gordillo N,Rodríguez S,Rodríguez EM

更新日期：1998-05-01 00:00:00

abstract：:Na+, K+-ATPase is one of major membrane proteins that has two subunits, alpha and beta. The alpha subunit has the ATPase activity and the ouabain binding site. Among four isoforms of the alpha subunit, expression of alpha1, alpha2, and alpha3, but not alpha4, is observed in matured rat brain. Ouabain is one of cardiac...

journal_title：Neuroscience letters

authors： Taguchi K,Kumanogoh H,Nakamura S,Maekawa S

更新日期：2007-02-08 00:00:00

abstract：:Neuropeptides, synthesized in dorsal root ganglia (DRG), are implicated in nociception and neurogenic inflammation. Alterations in DRG neuropeptide levels have been described in polyarthritic rats, but these models are associated with widespread systemic disease. Using mild adjuvant-mediated monoarthritis of the left ...

journal_title：Neuroscience letters

authors： Smith GD,Harmar AJ,McQueen DS,Seckl JR

更新日期：1992-03-30 00:00:00

abstract：:In newborns, hypoxia elicits defensive behaviors including awakening from sleep, body movements and crying. An inability to produce this defense response is a risk factor for sudden infant death syndrome and other respiratory control disorders. In this study, we examined the possibility that the defense response to hy...

journal_title：Neuroscience letters

authors： Bollen B,Bouslama M,Matrot B,D'Hooge R,Van den Bergh O,Gallego J

更新日期：2007-06-15 00:00:00

abstract：:Occurrence of neurocalcin, a calcium-binding protein with three EF hand motifs, was examined immunohistochemically in the rat olfactory epithelium and vomeronasal organ epithelium. Immunoreactivity was detected in receptor cells in these epithelia. Immunoreactions were distributed in cytoplasm associated with outer mi...

journal_title：Neuroscience letters

authors： Iino S,Kobayashi S,Okazaki K,Hidaka H

更新日期：1995-05-19 00:00:00

abstract：:Recombinant gamma-aminobutyric acid (GABA(A)) receptor channels containing alpha1beta2gamma2-subunits were transiently expressed in HEK293 cells. Modulation by diazepam (DZ) was investigated using the patch-clamp technique with a device for ultra-fast solution exchange. GABA activated Cl(-)-currents were potentiated w...

journal_title：Neuroscience letters

authors： Krampfl K,Lepier A,Jahn K,Franke C,Bufler J

更新日期：1998-11-13 00:00:00

abstract：:Diffusion MRI studies characterizing the changes in white matter (WM) due to vascular cognitive impairment, which includes all forms of small vessel disease are reviewed. We reviewed the usefulness of diffusion methods in discriminating the affected WM regions and its relation to cognitive impairment. These studies we...

journal_title：Neuroscience letters

authors： Raja R,Rosenberg G,Caprihan A

更新日期：2019-02-16 00:00:00

abstract：:In the present experiments it was tested whether the organic calcium antagonist verapamil has an influence on N-methyl-D-aspartate (NMDA) induced cortical field potentials (CFP) in neocortical slices of guinea pigs. NMDA (1 mumol/l) was applied via a micropipette by pressure pulses. Verapamil (60 mumol/l) was administ...

journal_title：Neuroscience letters

authors： Lücke A,Speckmann EJ

更新日期：1993-10-29 00:00:00

abstract：:The subventricular germinal zone (SVZ) retains an active population of stem cells and neural precursor cells throughout adulthood. EphrinB signaling mediates angiogenesis and vasculogenesis in the developing and adult brain. Recent studies indicate that molecules involved in angiogenesis often influence neurogenesis a...

journal_title：Neuroscience letters

authors： Katakowski M,Zhang Z,deCarvalho AC,Chopp M

更新日期：2005-09-16 00:00:00

abstract：:The possibility that single electrical shock stimulation of somatic afferent nerves could evoke a reflex response in vagal efferent nerves innervating the stomach was examined using anesthetized, artificially-ventilated rats. A single shock to a hindlimb afferent nerve (tibial nerve) produced two distinct reflex compo...

journal_title：Neuroscience letters

authors： Kimura A,Sato A,Sato Y,Suzuki A

更新日期：1996-05-24 00:00:00

abstract：:Recently, we reported that voluntary resistance wheel running with a resistance of 30% of body weight (RWR), which produces shorter distances but higher work levels, enhances spatial memory associated with hippocampal brain-derived neurotrophic factor (BDNF) signaling compared to wheel running without a load (WR) [17]...

journal_title：Neuroscience letters

authors： Lee MC,Inoue K,Okamoto M,Liu YF,Matsui T,Yook JS,Soya H

更新日期：2013-03-14 00:00:00

abstract：:Oxytocin (OT) modulation of synaptic transmission between olfactory bulb neurones has been implicated in the induction of maternal behaviour, but the mechanism of action is unknown. We examined the action of OT on gamma-aminobutyric acid(A) (GABA(A)) receptor-mediated spontaneous inhibitory postsynaptic currents (sIPS...

journal_title：Neuroscience letters

authors： Osako Y,Otsuka T,Taniguchi M,Oka T,Kaba H

更新日期：2000-07-28 00:00:00

abstract：:Mild cognitive impairment (MCI) is characterized by cognitive deficits which do not yet reach the threshold of dementia but represent a putative preclinical state of Alzheimer's disease (AD). Little is known about the neural correlates of delayed episodic memory which is among the earliest signs of cognitive decline i...

journal_title：Neuroscience letters

authors： Schönknecht OD,Hunt A,Toro P,Henze M,Haberkorn U,Schröder J

更新日期：2009-12-25 00:00:00

abstract：:A previous study of brain activation in normal subjects during a phonological (Phonemes) task and a lexical semantic (Words) task using positron-emission tomography [3] is complemented by new data after a method for image realignment was applied [17]. The pattern of cerebral blood flow increases associated with Words ...

journal_title：Neuroscience letters

authors： Démonet JF,Price C,Wise R,Frackowiak RS

更新日期：1994-11-21 00:00:00

abstract：:The pineal gland is innervated by pinealopetal peptidergic fibers originating in the hypothalamic nuclei which release arginine vasopressin (AVP) and arginine vasotocin (AVT) from their endings. Since the mechanism of AVT action on the pineal signal transduction and melatonin synthesis has not been determined so far, ...

journal_title：Neuroscience letters

authors： Novotná R,Jác M,Hájek I,Novotný I

更新日期：1999-03-05 00:00:00

abstract：:The neurotransmitter acetylcholine (ACh) is synthesized by the enzyme choline acetyltransferase (ChAT) and then transported into synaptic vesicles by the vesicular acetylcholine transporter (VAChT). Since the VAChT gene is located within the first intron of the ChAT gene, it is likely that expression of the two genes ...

journal_title：Neuroscience letters

authors： Holler T,Berse B,Cermak JM,Diebler MF,Blusztajn JK

更新日期：1996-07-12 00:00:00

abstract：:Coenzyme Q(10) (CoQ(10)) exerts neuroprotective effects in several in vivo and in vitro models of neurodegenerative disorders. However, the mechanisms of action are not fully understood. The aim in this study was to investigate whether oral administration of CoQ(10) could inhibit cytochrome c (cyt c) release from mito...

journal_title：Neuroscience letters

authors： Mitsumoto Y,Kobayashi S,Matsushima H,Muroyama A,Yoshimura I

更新日期：2009-09-29 00:00:00

abstract：:In Parkinson's disease, the progressive loss of dopaminergic neurons in the pars compacta of the substantia nigra leads to debilitating motor dysfunction. In the present study, we investigated the effects of treadmill exercise on the dopaminergic neuronal cell death in the substantia nigra and on the dopaminergic fibe...

journal_title：Neuroscience letters

authors： Yoon MC,Shin MS,Kim TS,Kim BK,Ko IG,Sung YH,Kim SE,Lee HH,Kim YP,Kim CJ

更新日期：2007-08-09 00:00:00

abstract：:As an integrative discipline, neuroscience can serve as a vehicle for the development of integrative thinking skills and broad-based scientific proficiency in undergraduate students. Undergraduate neuroscience curricula incorporate fundamental concepts from multiple disciplines. Deepening the explicit exploration of t...

journal_title：Neuroscience letters

authors： Basu AC,Hill AS,Isaacs AK,Mondoux MA,Mruczek REB,Narita T

更新日期：2021-01-18 00:00:00

abstract：:Morphine analgesia measured by the tail withdrawal test was examined in rats that were either restrained or left free during testing. It was found that restraint potentiated morphine analgesia and decreased the latency of the peak analgesic effect. Methysergide, a serotonin antagonist, and valine, which prevents the i...

journal_title：Neuroscience letters

authors： Kelly SJ,Franklin KB

更新日期：1984-02-24 00:00:00

abstract：:Elevated introcular pressure (IOP)-induced retinal neuron ischemic death includes an early phase of necrosis and prolonged phase of apoptosis. We used this ischemic model to observe the changes of sortilin and p75(NTR) protein expressions in rat retina. The results of Western blot analysis showed the expression of p75...

journal_title：Neuroscience letters

authors： Wei Y,Wang N,Lu Q,Zhang N,Zheng D,Li J

更新日期：2007-12-18 00:00:00

abstract：:The effects of quinolinic acid (QUIN) on glutamate-induced excitotoxicity were examined in primary cultures of rat cerebellar granule neurons. Exposing these neurons to QUIN (< or =2.5 mM) in the presence of glucose and Mg2+ had no effect on their viability. Although pretreating neurons with QUIN (10 microM) for 6 h d...

journal_title：Neuroscience letters

authors： Sei Y,Fossom L,Goping G,Skolnick P,Basile AS

更新日期：1998-01-30 00:00:00

abstract：:The irreversible labeling by [3H]flunitrazepam of three proteins with apparent molecular weights of 51,000 (P51), 55,000 (P55) and 59,000 (P59) was investigated using hippocampal membranes isolated from rats at various timepoints after birth. The present results indicate that [3H]flunitrazepam predominantly labels P55...

journal_title：Neuroscience letters

authors： Sieghart W,Mayer A

更新日期：1982-07-20 00:00:00

abstract：:Chewing and walking are two oscillatory behaviors performed on an everyday basis. The current study examined the impact chewing at different speeds (i.e. fast, slow, preferred) had on walking performance for fifteen young healthy adults (23.2 + 4.2 years) and fifteen healthy older participants (66.5 + 3.2 years). Chew...

journal_title：Neuroscience letters

authors： Samulski B,Prebor J,Armitano C,Morrison S

更新日期：2019-04-17 00:00:00

abstract：:We describe the measurement of beta-nerve growth factor (NGF) content in cerebrospinal fluid (CSF) from multiple sclerosis (MS) patients compared with CSF from age-matched normal subjects using a specific sandwich immunoassay (ELISA). During acute attacks patients exhibit a significant increase of NGF content compared...

journal_title：Neuroscience letters

authors： Laudiero LB,Aloe L,Levi-Montalcini R,Buttinelli C,Schilter D,Gillessen S,Otten U

更新日期：1992-11-23 00:00:00

abstract：:Protein kinase G (PKG) has been implicated in a variety of physiological functions including synaptic plasticity in the brain. This study investigated the involvement of dopamine D3 (D3) receptors in PKG-regulated dopamine release, long-term changes in gene expression and behavioral sensitization after repeated cocain...

journal_title：Neuroscience letters

authors： Lee DK,Oh JH,Yang JH,Youn B,Shim YB,Shim I,Wang JQ,Choe ES

更新日期：2013-04-29 00:00:00

abstract：:Segments of the mouse sciatic nerve were preloaded with either d-2,3-(3)H-Aspartic acid [nonmetabolizable analog of glutamate] or l-(14)C-proline and the release of these exogenous molecules was evaluated in the fractions of the perfusate following electrical or magnetic stimulation. The electrical stimulation (10Hz, ...

journal_title：Neuroscience letters

authors： Wieraszko A,Ahmed Z

更新日期：2009-07-10 00:00:00