The possible role of opiates in habituation of responses recorded in the reticular formation of the frog, to peripheral stimulation.

Abstract:

:Repeated stimulation can lead to a decrement in the amplitude of a response, or its disappearance. This is known as habituation. Responses recorded in the reticular formation of the brain to peripherally applied stimuli tend to habituate. Decerebration considerably reduces the occurrence of this habituation and naloxone reverses the effect. In decerebrate animals in which such responses rarely habituate, habituation can be induced by administration of D-Ala2,Met5-enkephalinamide and then reversed by a subsequent administration of naloxone. This would suggest that opiates are involved in habituation of responses recorded in the reticular formation of the frog.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Boxer MI

doi

10.1016/0304-3940(83)90093-9

subject

Has Abstract

pub_date

1983-09-19 00:00:00

pages

61-5

issue

1

eissn

0304-3940

issn

1872-7972

pii

0304-3940(83)90093-9

journal_volume

40

pub_type

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