Nitric oxide synthase immunoreactivity and NADPH-diaphorase activity in a subpopulation of intrinsic neurones of the guinea-pig heart.

abstract：:Using double-staining techniques, the distribution of NADPH-diaphorase (ND)- and nitric oxide synthase (NOS)-positive cells was compared in the periglomerular region of typical and atypical rat olfactory glomeruli. Dorsomedial and ventrolateral atypical glomeruli contained similar number of ND/NOS-positive periglomeru...

journal_title：Neuroscience letters

authors： Crespo C,Porteros A,Arévalo R,Briñón JG,Aijón J,Alonso JR

更新日期：1996-03-01 00:00:00

abstract：:The role of the serotonergic system in regulating the expression of estrogen receptor (ER) α in the hypothalamus was investigated in ovariectomized rats by injecting a serotonin synthesis inhibitor, parachlorophenylalanine (PCPA), or by destroying the dorsal raphe nucleus (DR). The number of ERα-immunoreactive (ir) ce...

journal_title：Neuroscience letters

authors： Ito H,Shimogawa Y,Kohagura D,Moriizumi T,Yamanouchi K

更新日期：2014-11-07 00:00:00

abstract：:The existence of neurons expressing preprogalanin mRNA in the monkey hippocampal formation was demonstrated using in situ hybridization of a radio-labelled cRNA probe transcribed from human preprogalanin cDNA. Specific hybridization occurred in neurons of the hilus of the dentate gyrus, fields CA1-3 in Ammon's horn, s...

journal_title：Neuroscience letters

authors： Evans HF,Huntley GW,Morrison JH,Shine J,Paxinos G

更新日期：1992-11-09 00:00:00

abstract：:Using a new polyclonal antibody against prostacyclin (PGI2)-synthase this enzyme was shown to be present in neuronal cells of bovine, rat and human brain, most abundantly in Purkinje cells of the cerebellum and cortical neurons, but not in glial cells. Western blots confirmed the specificity of the antibody and applie...

journal_title：Neuroscience letters

authors： Mehl M,Bidmon HJ,Hilbig H,Zilles K,Dringen R,Ullrich V

更新日期：1999-08-27 00:00:00

abstract：:The endogenously synthesized nonapeptide arginine vasopressin (AVP) is thought to be involved in transduction of photic information to the pineal gland. The enhancement of circulating AVP leads to a suppression of the nocturnal melatonin surge the mechanisms of which are unknown so far. We therefore studied the effect...

journal_title：Neuroscience letters

authors： Stehle J,Reuss S,Riemann R,Seidel A,Vollrath L

更新日期：1991-02-11 00:00:00

abstract：:Granulocyte-colony stimulating factor (G-csf) is a member of the hematopoietic growth factor family and demonstrates neuroprotective functions in neurodegenerative diseases. This study evaluated the radioprotective effects of G-csf in the suppression of hippocampal neurogenesis in adult mice undergoing irradiation. Th...

journal_title：Neuroscience letters

authors： Kim JS,Yang M,Jang H,Oui H,Kim SH,Shin T,Jang WS,Lee SS,Moon C

更新日期：2010-12-03 00:00:00

abstract：:Depolarizing afterpotentials (DAPs) were studied in intracellular recordings from neocortical slices bathed in tetrodotoxin (TTX) (1 microM) and tetraethylammonium chloride (TEA) (24 mM), to block voltage-dependent Na+ currents and most K+ currents. The DAP was Ca(2+)-dependent, in that its magnitude varied as a funct...

journal_title：Neuroscience letters

authors： Friedman A,Arens J,Heinemann U,Gutnick MJ

更新日期：1992-01-20 00:00:00

abstract：:Three dopamine receptor mRNAs were detected by reverse polymerase chain reaction in the rat forebrain during ontogeny. The D1 receptor mRNA gave a faint signal from gestational day 11 (G11) on, while the D1b receptor was not detectable before G12. The D3 receptor mRNA was slightly expressed at G11 and clearly present ...

journal_title：Neuroscience letters

authors： Cadoret MA,Jaber M,Bloch B

更新日期：1993-05-28 00:00:00

abstract：:We have found an APOE epsilon 4 allelic frequency of 0.289 (95% CI 0.195-0.383) in Spanish AD patients (n = 88; average age = 71.2 +/- 9.37) and of 0.061 (95% CI 0.023-0.099) in age-matched controls (n = 147; average age = 71.5 +/- 10.29). Remarkably no ApoE 4/4 subjects were observed in any of the age-matched control...

journal_title：Neuroscience letters

authors： Adroer R,Santacruz P,Blesa R,López-Pousa S,Ascaso C,Oliva R

更新日期：1995-04-21 00:00:00

abstract：:The melanocortin receptor type 2 (MC2R or adrenocorticotropic hormone, ACTH receptor) gene (MC2R) encodes a protein involved in regulation of adrenal cortisol secretion, important in the physiological response to stressors. A variant of MC2R, -179A>G, results in reduction of promoter activity and less adrenal action. ...

journal_title：Neuroscience letters

authors： Proudnikov D,Hamon S,Ott J,Kreek MJ

更新日期：2008-04-25 00:00:00

abstract：:Using a push-pull device, the release of endogenous proteins in the extracellular space was investigated in the CA1 region of the hippocampus of anaesthetized rats. With low-frequency stimulation of the Schaffer collaterals, there was a relatively stable release of 5 proteins (64, 54, 48, 45 and 16 kDa). A train of hi...

journal_title：Neuroscience letters

authors： Charriaut-Marlangue C,Aniksztejn L,Roisin MP,Ben-Ari Y

更新日期：1988-09-12 00:00:00

abstract：:We have investigated the presence of mutations in the parkin gene in patients with early-onset parkinsonism. Direct sequencing of the polymerase chain reaction (PCR) products showed a homozygous G deletion in the exon 7 (c.871delG) in one patient. This was a 38-year-old Moroccan woman with a history of parkinsonism of...

journal_title：Neuroscience letters

authors： Muñoz E,Pastor P,Martí MJ,Oliva R,Tolosa E

更新日期：2000-07-28 00:00:00

abstract：:The conversion of cellular prion protein (PrP(C)) to its protease-resistant isoform is involved in the pathogenesis of prion disease. Although PrP(C) is a ubiquitous glycoprotein that is present in various cell types, the physiological role of PrP(C) remains obscure. The present study aimed to determine whether PrP(C)...

journal_title：Neuroscience letters

authors： Watanabe T,Yasutaka Y,Nishioku T,Kusakabe S,Futagami K,Yamauchi A,Kataoka Y

更新日期：2011-06-01 00:00:00

abstract：:The study examined whether the generation of the forward propulsive force (PF) during gait initiation resulted mainly from the electromyogram activity of stance ankle plantar flexor muscles (APF) which 'push' on the ground as is generally claimed in the literature. Six unilateral above-knee amputees performed a specif...

journal_title：Neuroscience letters

authors： Michel V,Do MC

更新日期：2002-06-07 00:00:00

abstract：:Normal-learning children (NL) and children with learning disabilities (LD) reported their perceptions of unisensory (auditory or visual), concordant audiovisual (e.g. visual /apa/ and auditory /apa/) and conflicting (e.g. visual /aka/ and auditory /apa/) speech stimuli in quiet and noise (0 dB and -12 dB signal-to-noi...

journal_title：Neuroscience letters

authors： Hayes EA,Tiippana K,Nicol TG,Sams M,Kraus N

更新日期：2003-11-06 00:00:00

abstract：:Mounting evidence suggests a chronic pro-inflammatory state in individuals with bipolar disorder (BD). Stress exposure is known to exacerbate several inflammatory conditions as well as psychiatric disorders. Here, we analyzed plasma levels of pro-inflammatory cytokines and their soluble receptors to realistic acute ps...

journal_title：Neuroscience letters

authors： Wieck A,Grassi-Oliveira R,do Prado CH,Rizzo LB,de Oliveira AS,Kommers-Molina J,Viola TW,Marciano Vieira EL,Teixeira AL,Bauer ME

更新日期：2014-09-19 00:00:00

abstract：:Most single fibers of the cochlear nerve (CN) in 22 cats exhibited effects of mechanical interaction in one cochlea between two sounds applied binaurally, similarly to results in two cats in which the contralateral CN was transected. In 11 of 189 fibers, the spontaneous and/or the sound-evoked activity was suppressed ...

journal_title：Neuroscience letters

authors： Murata K,Tanahashi T,Horikawa J,Funai H

更新日期：1980-07-01 00:00:00

abstract：:Fish glial cells were obtained from cultivated segments of the optic nerve and raised in vitro. Two types of cells were identified as astrocyte- and oligodendrocyte-like glia by the monoclonal antibody Mab O1 (specific for oligodendrocytes) and the rabbit serum anti-goldfish glial fibrillary acidic protein (anti-G-GFA...

journal_title：Neuroscience letters

authors： Bastmeyer M,Beckmann M,Nona SM,Cronly-Dillon JR,Stuermer CA

更新日期：1989-06-19 00:00:00

abstract：:Although minocycline has been generally thought to have neuroprotective properties, the neuroprotective role of minocycline has not been investigated in the animal model of epilepsy. In this study, we investigated whether minocycline is neuroprotective against kainic acid (KA)-induced cell death through the caspase-de...

journal_title：Neuroscience letters

authors： Heo K,Cho YJ,Cho KJ,Kim HW,Kim HJ,Shin HY,Lee BI,Kim GW

更新日期：2006-05-08 00:00:00

abstract：:The majority of previous studies which have explored the mechanisms underlying perception of the direction of gravity in static roll tilt have proposed that the tendency to estimate the subjective visual vertical (SVV) as tilted towards body tilt ('Aubert effect') arises from an underestimation of perceived body tilt....

journal_title：Neuroscience letters

authors： Ceyte H,Cian C,Trousselard M,Barraud PA

更新日期：2009-10-02 00:00:00

abstract：:Retrograde axonal transport and fluorescent retrograde labelling of neurons were investigated in a crustacean motor system. A fluorescent tracer (Granular blue) was injected into an antennal muscle of rock lobster in order to identify the motor neurons innervating it. After an appropriate post-injection survival time,...

journal_title：Neuroscience letters

authors： Rossi-Durand C,Sorensen KE

更新日期：1985-04-09 00:00:00

abstract：:Increasing evidence suggests a correlation between cytokine-induced nitric oxide synthase (iNOS) and demyelination in Multiple sclerosis (MS). Inhibition of iNOS may therefore be a novel therapeutic approach in MS. To test an antisense oligodeoxynucleotide (ODN) knockdown strategy for inhibiting iNOS, we used lipopoly...

journal_title：Neuroscience letters

authors： Ding M,Zhang M,Wong JL,Voskuhl RR,Ellison GW

更新日期：1996-12-13 00:00:00

abstract：:The brains of 7 dogs aged 6 to 18 years have been histochemically and immunohistochemically investigated at the light- and electron microscopy levels for preamyloid deposits and amyloid fibrils to verify the hypothesis that the accumulation of cleavage products of amyloid precursor protein is related not only to Alzhe...

journal_title：Neuroscience letters

authors： Giaccone G,Verga L,Finazzi M,Pollo B,Tagliavini F,Frangione B,Bugiani O

更新日期：1990-07-03 00:00:00

abstract：:Mitochondrial Ca(2+) controls numerous cell functions, such as energy metabolism, reactive oxygen species generation, spatiotemporal dynamics of Ca(2+) signaling, cell growth and death in various cell types including neurons. Mitochondrial Ca(2+) accumulation is mainly mediated by the mitochondrial Ca(2+) uniporter (M...

journal_title：Neuroscience letters

authors： Jakob R,Beutner G,Sharma VK,Duan Y,Gross RA,Hurst S,Jhun BS,O-Uchi J,Sheu SS

更新日期：2014-07-11 00:00:00

abstract：:Amyloid proteins are a group of proteins that can polymerize into cross beta-sheeted amyloid species. We have found that enhancing cellular 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) formazan exocytosis is a common property of bioactive amyloid species formed from all of the amyloid proteins te...

journal_title：Neuroscience letters

authors： Liu Y,Ritter C,Riek R,Schubert D

更新日期：2006-10-09 00:00:00

abstract：:This study aimed to investigate the effects of ghrelin, as a neuroprotective agent, on cognitive impairment and apoptosis pathway in methamphetamine-treated male rats. Sixty adult male Wistar rats were randomly divided into six groups (n = 10): Saline/Saline (SS), Saline/Ghrelin (SG), Methamphetamine/Simultaneous Sali...

journal_title：Neuroscience letters

authors： Fallahi S,Babri S,Farajdokht F,Ghiasi R,Soltani Zangbar H,Karimi P,Mohaddes G

更新日期：2019-08-10 00:00:00

abstract：:Central diabetes insipidus can occur after hypothalamic-hypophyseal tract injury. This injury is linked with a deficit in circulating vasopressin and oxytocin, which are produced in the supraoptic nuclei and the hypothalamic paraventricular nuclei. Previous studies indicate that an ectopic neural lobe forms after pitu...

journal_title：Neuroscience letters

authors： Feng Z,Ou Y,Zhou M,Wu G,Ma L,Zhang Y,Liu Y,Qi S

更新日期：2018-04-23 00:00:00

abstract：:Peroxidase-antiperoxidase (PAP) immunocytochemistry at the electron microscopic level was used to describe the fine structural characteristics of vascular connections between vasopressin (VP)-immunoreactive neuronal elements and cerebral microvessels in the rat. In the majority of connections, somata or neural process...

journal_title：Neuroscience letters

authors： Jójárt I,Joó F,Siklós L,László FA

更新日期：1984-10-12 00:00:00

abstract：:In this study, we investigated the role of nitric oxide (NO) in neuronal cell death in the lipopolysaccharide (LPS)-treated rat hippocampal slice culture. Neuronal cell death was induced after a LPS treatment in a rat hippocampal slice. The region and time course of the cell death caused by LPS were different from tho...

journal_title：Neuroscience letters

authors： Lee P,Son D,Lee J,Kim YS,Kim H,Kim SY

更新日期：2003-09-25 00:00:00

abstract：:Twenty years ago, Wolfe, Xia, and Selkoe identified two aspartate residues in Alzheimer's presenilin protein that constitute the active site of the γ-secretase complex. Mutations in the genes encoding amyloid precursor protein (APP) or presenilin (PS) cause early onset familial Alzheimer's disease (AD), and sequential...

journal_title：Neuroscience letters

authors： Xia W

更新日期：2019-05-14 00:00:00