Granulocyte-colony stimulating factor ameliorates irradiation-induced suppression of hippocampal neurogenesis in adult mice.

abstract：:In the neuritic plaques of Alzheimer's disease, abnormal neuritic processes cluster around a core of beta-amyloid protein. Previous data have shown that beta 1-28, a peptide homologous to the first 28 amino acid residues of beta-amyloid protein, enhanced survival without affecting neuritic extension or branching in cu...

journal_title：Neuroscience letters

authors： Whitson JS,Glabe CG,Shintani E,Abcar A,Cotman CW

更新日期：1990-03-14 00:00:00

abstract：:Kynurenic acid (KYNA), a neuroactive metabolite of tryptophan that acts on different receptors (e.g. those of N-methyl-D-aspartate (NMDA) and presynaptic α7 nicotinic acetylcholine (nACh)), exerts fundamentally antiglutamatergic effects. In view of its antiglutamatergic properties, an elevation of the KYNA level withi...

journal_title：Neuroscience letters

authors： Demeter I,Nagy K,Farkas T,Kis Z,Kocsis K,Knapp L,Gellert L,Fülöp F,Vecsei L,Toldi J

更新日期：2013-10-11 00:00:00

abstract：:Familial Alzheimer's disease (AD) due to PSEN1 mutations provides an opportunity to examine AD biomarkers in persons in whom the diagnosis is certain. We describe a 55 year-old woman with clinically probable AD and a novel PSEN1 mutation who underwent genetic, clinical, biochemical and magnetic resonance and nuclear i...

journal_title：Neuroscience letters

authors： Ringman JM,Gylys KH,Medina LD,Fox M,Kepe V,Flores DL,Apostolova LG,Barrio JR,Small G,Silverman DH,Siu E,Cederbaum S,Hecimovic S,Malnar M,Chakraverty S,Goate AM,Bird TD,Leverenz JB

更新日期：2011-01-10 00:00:00

abstract：:Dehydroepiandrosterone sulfate (DHEAS) dose-dependently inhibited [3H]norepinephrine (NE) secretion and the corresponding [Ca2+]i rise induced by the nicotinic receptor agonist 1,1-dimethyl-4-phenylpoperazimium (DMPP) in bovine chromaffin cells. DHEAS at 10 microM, the physiological concentration in human serum, signi...

journal_title：Neuroscience letters

authors： Liu PS,Lin MK,Hsieh HL

更新日期：1996-02-09 00:00:00

abstract：:Several studies demonstrated that the overexpression of miR-124 in neural stem cells (NSCs) could lead the NSCs to differentiate into neurons and astrocytes, which may be important for functional recovery in spinal cord injury. The present study attempted to explore the potential repairing effect of the NSCs transfect...

journal_title：Neuroscience letters

authors： Xu W,Li P,Qin K,Wang X,Jiang X

更新日期：2012-10-31 00:00:00

abstract：:Vesicular monoamine transporter 2 (VMAT2) is responsible for packing dopamine into vesicles, and reduces the effects of neurotoxins by sequestering them into vesicles. In this report, we tested the hypothesis that VMAT2 is associated with Lewy body (LB) formation by immunohistochemical staining of midbrain and cortica...

journal_title：Neuroscience letters

authors： Yamamoto S,Fukae J,Mori H,Mizuno Y,Hattori N

更新日期：2006-04-03 00:00:00

abstract：:Involvement of the ipsilateral hemisphere during planning of reaching movements is still matter of debate. While it has been demonstrated that the contralateral hemisphere is dominant in visuo-motor integration, involvement of the ipsilateral hemisphere has also been proposed. Furthermore, a dominant role for left pos...

journal_title：Neuroscience letters

authors： Busan P,Jarmolowska J,Semenic M,Monti F,Pelamatti G,Pizzolato G,Battaglini PP

更新日期：2009-08-28 00:00:00

abstract：:We have investigated the effect of ethanol upon vasopressin (AVP) content in brain and upon in-vitro release of AVP from the rat median eminence. In-vitro ethanol concentrations (5-25 mM), comparable to behaviorally relevant blood ethanol levels, induce a substantial inhibition of AVP release from the median eminence,...

journal_title：Neuroscience letters

authors： Brinton RE,Gruener R,Deshmukh P,Yamamura HI

更新日期：1986-06-18 00:00:00

abstract：:Previous in vivo studies have indicated that both arginine vasopressin (AVP) and angiotensin II (ANG II) can modulate the baroreflex by acting on the area postrema (AP). In the present study, effects of AVP and ANG II on AP neuronal activity were investigated by recording extracellular activity in a rabbit brainstem s...

journal_title：Neuroscience letters

authors： Cai Y,Bishop VS

更新日期：1995-05-05 00:00:00

abstract：:The purpose of this study was to measure the average anterior commissure (AC) volume of normal subjects in their 20s or 40s and to determine the effects of gender and age on AC volume. Magnetic resonance brain images were obtained for 93 people in their 20s (46 men, 47 women) and 87 in their 40s (36 men, 51 women). To...

journal_title：Neuroscience letters

authors： Choi MH,Kim JH,Yeon HW,Choi JS,Park JY,Jun JH,Lee BY,Kim HJ,Tack GR,Chung SC

更新日期：2011-08-15 00:00:00

abstract：:By a double-labeling method combining the retrograde tracing of horseradish peroxidase and the immunocytochemical technique, serotonin-, substance P- or leucine-enkephalin-like immunoreactive neurons in the midbrain periaqueductal gray (PAG) and the nucleus raphe dorsalis (DR) of the rat were found to send projection ...

journal_title：Neuroscience letters

authors： Li YQ,Jia HG,Rao ZR,Shi JW

更新日期：1990-11-27 00:00:00

abstract：:From the effects of selective lesions it is concluded that opiate receptors are located on dopamine (DA) cell-bodies and/or dendrites as well as on GABA nerve-terminals in substantia nigra. ...

journal_title：Neuroscience letters

authors： Llorens-Cortes C,Pollard H,Schwartz JC

更新日期：1979-05-01 00:00:00

abstract：:The blood-brain barrier (BBB) plays an important role in controlling the passage of molecules from the blood to the extracellular fluid environment of the brain. An immortalised rat brain endothelial cell line (GPNT) was used to investigate the mechanisms underlying dexamethasone-induced decrease in paracellular perme...

journal_title：Neuroscience letters

authors： Romero IA,Radewicz K,Jubin E,Michel CC,Greenwood J,Couraud PO,Adamson P

更新日期：2003-06-26 00:00:00

abstract：:Employing double anterograde axonal tracing in combination with intracortical microstimulation, we examined the distribution patterns of corticosubthalamic inputs from forelimb representations of the dorsal (PMd) and ventral (PMv) divisions of the premotor cortex in the macaque monkey. The inputs from the PMd and PMv ...

journal_title：Neuroscience letters

authors： Nambu A,Tokuno H,Inase M,Takada M

更新日期：1997-12-12 00:00:00

abstract：:Reflex micturition was evoked in both non-immobilized (n = 5) and immobilized (n = 5) decerebrate cats by filling the bladder with physiological saline. Intracellular recordings were made from pudendal motoneurons (PU-MNs; n = 14) throughout the periods of before, during and after reflex micturition. The changes in th...

journal_title：Neuroscience letters

authors： Shimoda N,Takakusaki K,Nishizawa O,Tsuchida S,Mori S

更新日期：1992-02-03 00:00:00

abstract：:Following peripheral nerve section, the cell body and proximal axon undergo various physiological and morphological changes which may be associated with regrowth. We found that axotomy reduced the amplitude and duration of the afterhyperpolarization (AHP) of the action potential (AP) of bullfrog sympathetic neurones. ...

journal_title：Neuroscience letters

authors： Kelly ME,Gordon T,Shapiro J,Smith PA

更新日期：1986-06-18 00:00:00

abstract：:Converging evidence demonstrates an important role for gangliosides in brain function and neurodegenerative diseases. Exogenous GM1 is broadly neuroprotective, including in rodent, feline, and primate models of Parkinson's disease, and has shown positive effects in clinical trials. We and others have shown that inhibi...

journal_title：Neuroscience letters

authors： Dhanushkodi A,Xue Y,Roguski EE,Ding Y,Matta SG,Heck D,Fan GH,McDonald MP

更新日期：2019-01-23 00:00:00

abstract：:The present study was designed to test the hypothesis that alpha-tocopherol (Vit. E) and pyrrolidine dithiocarbamate (PDTC) might exert direct effects on alcohol-induced contractions of canine basilar cerebral arteries. After precontraction of arterial ring segments with ethanol, PDTC (10(-8)-10(-6) M) and Vit. E (10(...

journal_title：Neuroscience letters

authors： Li W,Zheng T,Altura BT,Altura BM

更新日期：2001-03-30 00:00:00

abstract：:Serotonin (5-HT) has been implicated in the regulation of circadian rhythms through its actions on the suprachiasmatic nucleus (SCN). Recent data suggests that, along with excitatory amino acids, serotonin may be important in the neural pathway that mediates the transmission of photic information to the circadian syst...

journal_title：Neuroscience letters

authors： Moyer RW,Kennaway DJ

更新日期：1999-08-27 00:00:00

abstract：:Inhibition of return (IOR) refers to the slowing of responses to a target that appears in the same location as a previous event. Many researchers have speculated that IOR arises from inhibitory neural processes that have developed through evolution to facilitate efficient search patterns by biasing the action and/or a...

journal_title：Neuroscience letters

authors： Welsh TN,Elliott D,Anson JG,Dhillon V,Weeks DJ,Lyons JL,Chua R

更新日期：2005-09-09 00:00:00

abstract：:The dopamine modulation of microiontophoretic application of antagonists of glutamate metabotropic synaptic transmission was studied in the sensory motor cortex of awake cats during instrumental conditioned reflex. The substances depressed the background and intensity of evoked impulse activity of pyramidal neurons of...

journal_title：Neuroscience letters

authors： Storozhuk VM,Khorevin VI,Rozumna NM,Villa AE,Tetko IV

更新日期：2004-02-12 00:00:00

abstract：:Previous studies have reported that intrahemispheric connections between area 17 (V1, striate cortex) and other cortical visual areas are not point-to-point, but instead have some degree of convergence and divergence. Many pathological conditions can interfere with the normal development of patterns of cortico-cortica...

journal_title：Neuroscience letters

authors： Bock AS,Olavarria JF

更新日期：2011-09-01 00:00:00

abstract：INTRODUCTION:The saccadic paradigm has been used to investigate specific cortical networks involving attention. The behavioral and electrophysiological investigations of the SEM contribute significantly to the understanding of attentive patterns presented of neurological and psychiatric disorders and sports performance...

journal_title：Neuroscience letters

authors： Bittencourt J,Machado S,Teixeira S,Schlee G,Salles JI,Budde H,Basile LF,Nardi AE,Cagy M,Piedade R,Sack AT,Velasques B,Ribeiro P

更新日期：2012-08-15 00:00:00

abstract：:Implicit detection of statistical regularities is thought to be a ubiquitous facet of cognition; yet, we know little about statistical learning (SL) over time. A recent study showed that visual SL can be observed at 24 h post stimulus (Kim et al., 2009 [14]). Here we sought to obtain a finer-grained picture of visual ...

journal_title：Neuroscience letters

authors： Arciuli J,Simpson IC

更新日期：2012-05-31 00:00:00

abstract：:Single-unit recordings were made from the zona incerta of the subthalamic region of conscious sheep during ingestion. Some cells responded to ingestion and not to associated chewing, arousal or odour stimuli. Most cells changed their activity shortly after food entered the mouth and throughout ingestion, but a few res...

journal_title：Neuroscience letters

authors： Kendrick KM,Baldwin BA

更新日期：1986-01-30 00:00:00

abstract：:Capsaicin, a neurotoxin which impairs some primary afferent nerve fibers, was locally applied to the mesenteric nerve trunks of adult guinea pigs. The effect of capsaicin was studied on contractile responses of the ileum to mesenteric nerve stimulation (20 Hz). Exposure of the mesenteric nerve to capsaicin (1 microM) ...

journal_title：Neuroscience letters

authors： Jin JG,Takaki M,Nakayama S

更新日期：1989-11-20 00:00:00

abstract：:The presence of neuromelanic pigment in neurons of the rat substantia nigra (SN) is a matter of controversy. The presence of neuromelanin in the SN of 15--24-month-old rats was investigated by electron microscopy (EM) and the findings compared to the morphology and distribution of neuromelanin in SN of dogs. In the ra...

journal_title：Neuroscience letters

authors： DeMattei M,Levi AC,Fariello RG

更新日期：1986-12-03 00:00:00

abstract：:To explore the possible cellular source and mechanism of apolipoprotein E (apoE) expression in mechanical injured neuronal cultures. Primary cultured mouse cortical neurons were subjected into mechanical injury by needle scratching. The conditioned medium of wild type (WT) primary mouse astrocytes was collected and ad...

journal_title：Neuroscience letters

authors： Yin C,Zhou S,Jiang L,Sun X

更新日期：2012-04-25 00:00:00

abstract：:Telmisartan is known to block angiotensin (Ang) II type-1 receptors (AT(1)R), and also activate peroxisome proliferator-activated receptor gamma (PPARgamma) signaling. Recently, PPARgamma has been implicated as a regulator of cellular proliferation and inflammatory responses. In the present study, we investigated the ...

journal_title：Neuroscience letters

authors： Haraguchi T,Takasaki K,Naito T,Hayakawa K,Katsurabayashi S,Mishima K,Iwasaki K,Fujiwara M

更新日期：2009-10-30 00:00:00

abstract：:Among the techniques used to reduce spatial neglect's symptoms, left neck muscle vibration (NMV) is alluring because it does not require the patient's attentional co-operation. The aim of this study was to determine the type of NMV-associated feedback that induced the most intense and longest-lasting egocentric post-e...

journal_title：Neuroscience letters

authors： Ceyte H,Beis JM,Ceyte G,Caudron S

更新日期：2021-01-19 00:00:00