In vitro inhibition of vasopressin release in brain by behaviorally relevant ethanol concentrations.

abstract：:By using the whole-cell recording technique the Na+ current in cultured melanotrophs of the adult rat pituitary was studied. The Na+ current was eliminated by 1 microM TTX and its equilibrium potential confirmed that it was carried predominantly by Na+. The activation threshold was near -40 mV and half-maximal activat...

journal_title：Neuroscience letters

authors： Kehl SJ

更新日期：1994-01-03 00:00:00

abstract：:Glycinergic inhibitory neurotransmission plays a pivotal role in the development of neuropathic pain. The glycine concentration in the synaptic cleft is controlled by the glycine transporters GlyT1 and GlyT2. GlyT1 is expressed throughout the central nervous system, while GlyT2 is exclusively located in glycinergic ne...

journal_title：Neuroscience letters

authors： Schlösser L,Barthel F,Brandenburger T,Neumann E,Bauer I,Eulenburg V,Werdehausen R,Hermanns H

更新日期：2015-07-23 00:00:00

abstract：:Previous work from our laboratory has shown that naïve Wistar Audiogenic Rats (WARs), a genetic model of reflex epilepsy in which seizures are induced by high-intensity sound stimulation (120 dB SPL), are seizure-prone to a variety of pro-convulsive stimuli (e.g., transauricular electroshock, pentylenetetrazole and pi...

journal_title：Neuroscience letters

authors： Magalhães LH,Garcia-Cairasco N,Massensini AR,Doretto MC,Moraes MF

更新日期：2004-10-07 00:00:00

abstract：:Patients with unilateral (n = 14) and bilateral (n = 4) herniorrhaphy participated in this study. With bilateral herniorrhaphy, at the end of the surgery, the wound was infiltrated with a solution of bupivacaine 0.5% and ketamine 0.3% on one side and a solution of bupivacaine 0.5% only, on the other. With unilateral h...

journal_title：Neuroscience letters

authors： Tverskoy M,Oren M,Vaskovich M,Dashkovsky I,Kissin I

更新日期：1996-08-30 00:00:00

abstract：:NCB-20 cells expressed m1- and m4-muscarinic acetylcholine receptor (mAChR) mRNAs, while NG108-15 cells expressed only m4-mAChR mRNA. Butyrate induced a time-dependent increase in the level of m1-mAChR mRNA with no change in the m4-mAChR mRNA level in NCB-20 cells. Similarly, butyrate did not affect the m4-mAChR mRNA ...

journal_title：Neuroscience letters

authors： Fukamauchi F,Mataga N,Wang YJ,Chuang DM

更新日期：1996-07-05 00:00:00

abstract：:We examined astroglial cells in the brain of the pygmy shrew Sorex minutus (Insectivora). For that purpose we labeled glial fibrillary acidic protein (GFAP) immunohistochemically in brain sections with a polyclonal antibody. Antigen retrieval experiments were performed to counteract formaldehyde fixation masking of GF...

journal_title：Neuroscience letters

authors： Olkowicz S,Bartkowska K,Rychlik L,Turlejski K

更新日期：2004-09-23 00:00:00

abstract：:Spirulina maxima is a blue-green micro alga that contains abundant amounts of proteins (60-70%), vitamins, chlorophyll a, and C-phycocyanin (C-PC). It has been shown to reduce oxidative stress, and prevent diabetes and non-alcoholic fatty liver disease. However, it is unclear whether Spirulina maxima 70% ethanol extra...

journal_title：Neuroscience letters

authors： Koh EJ,Kim KJ,Choi J,Kang DH,Lee BY

更新日期：2018-04-23 00:00:00

abstract：:The influence of the medial prefrontal cortex (PFC) on mesolimbic dopamine activity was studied with electrophysiological techniques and in vivo voltammetry in the chloral hydrate-anesthetized male rat. Glutamate injected into the PFC selectively increased burst firing of single dopamine cells in the ventral tegmental...

journal_title：Neuroscience letters

authors： Murase S,Grenhoff J,Chouvet G,Gonon FG,Svensson TH

更新日期：1993-07-09 00:00:00

abstract：:In brainstem slices of guinea pigs perfused with artificial cerebro-spinal fluid (ACSF), the discharge of all the spontaneously active neurons of the medial vestibular nucleus (MVN) is regular. It has been reported that prolonged exposure to a low Ca(2+) medium could induce these neurons to fire bursts of spikes. In t...

journal_title：Neuroscience letters

authors： Ris L,Godaux E

更新日期：2001-01-12 00:00:00

abstract：:The distribution of substance P (SP)-like immunoreactivity in the rat retina was investigated by immunohistochemistry. SP-positive cells were found throughout the retina. The majority of them were located in the proximal portion of the inner nuclear layer and the processes from these cells directed to the inner plexif...

journal_title：Neuroscience letters

authors： Fukuda M,Kuwayama Y,Shiosaka S,Ishimoto I,Shimizu Y,Takagi H,Inagaki S,Sakanaka M,Semba E,Takatsuki K,Tohyama M

更新日期：1981-05-29 00:00:00

abstract：:Repetitive ischemia causes more severe damage than a single insult of comparable duration. Gerbils were followed for 1 month postrepetitive ischemia and 100% mortality was demonstrated in the unprotected ischemia group by 12 days postischemia. Significant protection against mortality due to repetitive ischemia was off...

journal_title：Neuroscience letters

authors： McCrea S,Shuaib A,Wishart T,Ijaz S

更新日期：1994-03-28 00:00:00

abstract：:The effect of prenatal ethanol exposure on the number of parvalbumin-immunoreactive (PA+) GABAergic neurons in the adult rat anterior cingulate cortex was determined. Pregnant Long-Evans rats were maintained on one of three diets throughout gestation: an ethanol-containing liquid diet, a similar, control liquid diet w...

journal_title：Neuroscience letters

authors： Moore DB,Quintero MA,Ruygrok AC,Walker DW,Heaton MB

更新日期：1998-06-12 00:00:00

abstract：:By means of light microscopic autoradiography, binding sites for the gamma-aminobutyric acid (GABA) analogues, 4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridin-3-ol ([7-3H]THIP), [3H]isoguvacine and [3H]baclofen were found on many cultured cerebellar and spinal neurons of fetal and newborn rats. The number of neurons labelle...

journal_title：Neuroscience letters

authors： Hösli E,Krogsgaard-Larsen P,Hösli L

更新日期：1985-10-24 00:00:00

abstract：:The effects of glutamate, glutamate receptor agonists and substances that affect glutamate responses were studied, using the whole-cell patch-clamp technique, on neurons isolated from adult rat dorsal root ganglia. In current-clamp, glutamate (100 microM) or the excitatory amino acid receptor agonist N-methyl-D-aspart...

journal_title：Neuroscience letters

authors： Lovinger DM,Weight FF

更新日期：1988-12-05 00:00:00

abstract：:Traumatic spinal cord injury (SCI) is a devastating condition of CNS which leads to loss of sensory as well as motor functions. Secondary damage after SCI initiates cascade of events that creates an inhibitory milieu for axonal growth and repair. Combinatorial therapies are the hope to attenuate secondary injury progr...

journal_title：Neuroscience letters

authors： Bhattacharyya S,Dinda A,Vishnubhatla S,Anwar MF,Jain S

更新日期：2021-01-10 00:00:00

abstract：:Neuroimmune mechanisms play critical roles in brain development and can be impacted by early life adversity. Microglia are the resident immune cells in the brain, with both sex-specific and region-specific developmental profiles. Since early life adversity is associated with several neuropsychiatric disorders with dev...

journal_title：Neuroscience letters

authors： Gildawie KR,Orso R,Peterzell S,Thompson V,Brenhouse HC

更新日期：2020-11-01 00:00:00

abstract：:Afferent fibers ending in nerve-end neuromas generate spontaneous impulse discharge which has been implicated as a cause of paraesthesias and pain following peripheral nerve injury in man. We now show in rats that the anticonvulsant drug phenytoin (PT), applied systemically or topically onto desheathed neuromas, suppr...

journal_title：Neuroscience letters

authors： Yaari Y,Devor M

更新日期：1985-07-04 00:00:00

abstract：:In the caudal postcentral finger region near or in the anterior bank of the intraparietal sulcus of alert monkeys, we found neurons that were activated selectively by the contact of the hand to certain common objects such as bottle brushes, acrylic plates, parts of the stabilized monkey's chair, etc. All of these neur...

journal_title：Neuroscience letters

authors： Iwamura Y,Tanaka M,Hikosaka O,Sakamoto M

更新日期：1995-02-17 00:00:00

abstract：:The pharmacology of the metabotropic glutamate receptor (mGluR)-mediated potentiation of N-methyl-D-aspartate (NMDA)-evoked depolarisations in the CA1 region of rat hippocampal slices was investigated using an extracellular grease-gap method. The group I and II mGluR agonist (1S,3R)-1-aminocyclopentane-1,3-dicarboxyli...

journal_title：Neuroscience letters

authors： Fitzjohn SM,Irving AJ,Palmer MJ,Harvey J,Lodge D,Collingridge GL

更新日期：1996-01-26 00:00:00

abstract：:Ifenprodil is an atypical N-methyl-D-aspartate (NMDA) receptor antagonist that selectively blocks receptors containing the NR2B subunit. It has been proposed that ifenprodil may act at a stimulatory polyamine site on NMDA receptors, although interactions between ifenprodil and polyamines are non-competitive. NMDA rece...

journal_title：Neuroscience letters

authors： Pahk AJ,Williams K

更新日期：1997-03-28 00:00:00

abstract：:Dibutyrylcytidine 3',5'-cyclic monophosphate (Bt2cCMP) stimulated neurite outgrowth in rat pheochromocytoma PC12 cells in a dose-dependent manner at the dose range from 0.5 mM to 6 mM. About 25% of the cells had neurites in response to 6 mM Bt2cCMP. In contrast with the effect of nerve growth factor (NGF) which increa...

journal_title：Neuroscience letters

authors： Yanagida M,Gohda E,Yamamoto I

更新日期：1990-07-13 00:00:00

abstract：:Although neural stem cell (NSC) transplantation has been investigated as a promising tool for reconstituting damaged brains, recent evidences suggest that NSCs may rescue the brain via paracrine effects rather than by direct cell replacements. In this study, we attempted to determine the neuroprotective effect of NSC-...

journal_title：Neuroscience letters

authors： Lim HC,Lee ST,Chu K,Joo KM,Kang L,Im WS,Park JE,Kim SU,Kim M,Cha CI

更新日期：2008-04-25 00:00:00

abstract：:Considering the multiplicity of symptoms associated with multiple sclerosis (MS), there is possibility that hypocretin system function might be involved in the pathogenesis of the disease. The current study aimed to investigate the hypocretin-1 levels in cerebrospinal fluid (CSF) of MS patients in relation to differen...

journal_title：Neuroscience letters

authors： Papuć E,Stelmasiak Z,Grieb P,Paweł G,Rejdak K

更新日期：2010-04-19 00:00:00

abstract：:Pain threshold and pain tolerance of heat noxious stimuli were assessed to determine whether they are equivalent when measured at three equidistant sites of both volar forearms. Heat pain threshold and tolerance were measured in 18 healthy volunteers using a standard stimulation device consisting of a thermode. Pain t...

journal_title：Neuroscience letters

authors： Schaffner N,Wittwer A,Kut E,Folkers G,Benninger DH,Candia V

更新日期：2008-08-08 00:00:00

abstract：:Mental simulation of movements has been widely used to infer about representational aspects of action. On a daily basis, motor planning and execution depends crucially both upon vision and kinesthesia. What if the former is lost? In this study we investigate the physiological changes induced during a mental simulation...

journal_title：Neuroscience letters

authors： Imbiriba LA,Rodrigues EC,Magalhães J,Vargas CD

更新日期：2006-05-29 00:00:00

abstract：:The membrane mechanisms associated with Cl- conductance activated by GABA in spinal and hippocampal neurons cultured from the embryonic mouse and rat have been studied with voltage- and patch-clamp techniques. The elementary mechanism underlying the conductance response is predominantly all-or-none with both similar a...

journal_title：Neuroscience letters

authors： Barker JL,Owen DG,Segal M

更新日期：1984-06-29 00:00:00

abstract：:In experiments using a synaptosomal preparation from the striatum and nucleus accumbens, somatostatin caused a dose-dependent increase in dopamine synthesis. This increase was additive with that produced by 8-BrcAMP but not with that produced by the phorbol ester 12-O-tetradecanoyl-phorbol-13-acetate (TPA), and was bl...

journal_title：Neuroscience letters

authors： Chowdhury M,Steardo L,Fillenz M

更新日期：1987-11-23 00:00:00

abstract：:The sulphur-containing acidic amino acids (SAAs) display neuroexcitatory actions similar to those of L-glutamate and are widely regarded as bona fide transmitter candidates. In this study, L-cysteine sulphinic acid, L-cysteic acid, DL-homocysteic acid and L-homocysteine sulphinic acid were investigated for their abili...

journal_title：Neuroscience letters

authors： Porter RH,Roberts PJ

更新日期：1993-05-14 00:00:00

abstract：:Normal aging is associated with chronic oxidative stress. In the basal ganglia, oxidative stress may contribute to the increased risk of Parkinson's disease in the elderly. Neurons are thought to actively utilize compensatory defense mechanisms, such as heat shock proteins (HSPs), to protect from persisting stress. De...

journal_title：Neuroscience letters

authors： Gupte AA,Morris JK,Zhang H,Bomhoff GL,Geiger PC,Stanford JA

更新日期：2010-03-19 00:00:00

abstract：:Harmonically rich sounds have been shown to be processed more efficiently by the human brain compared to single sinusoidal tones. To control for stimulus complexity as a potentially confounding factor, tones and equally complex spectrally rotated sounds, have been used in the present study to investigate the role of t...

journal_title：Neuroscience letters

authors： Christmann CA,Lachmann T,Berti S

更新日期：2014-10-03 00:00:00