Reconsideration of the concept of enhanced static fusimotor drive in rigidity in patients with Parkinson's disease.

abstract：:The Amphibalanus amphitrite barnacle is a sessile marine crustacean and a major constituent of benthic as well as intertidal communities. A. amphitrite is also an important component of biofouling on artificial substrates. The role of nitric oxide (NO) was recently observed in the settlement of this species. In this w...

journal_title：Neuroscience letters

authors： Gallus L,Ferrando S,Gambardella C,Faimali M,Piazza V,Masini MA

更新日期：2013-10-25 00:00:00

abstract：:We immunohistochemically examined the expression of glycogen synthase kinase-3beta (GSK-3beta) in the brains of Parkinson's disease (PD) patients. GSK-3beta was localized in punctate structures in the cytosol of subsets of neurons in the midbrain and upper pons. GSK-3beta was also localized in Lewy bodies (LBs) as was...

journal_title：Neuroscience letters

authors： Nagao M,Hayashi H

更新日期：2009-01-09 00:00:00

abstract：:In human caudate and cortex membranes, [3H]serotonin ([3H]5-HT) labels 5-HT1A and 5-HT1C recognition sites which show nanomolar affinity for 8-OH-DPAT (8-hydroxy-2-(di-n-propylamino)-tetralin) and mesulergine respectively, whereas no 5-HT1B binding could be identified. However, the majority of the sites labelled by [3...

journal_title：Neuroscience letters

authors： Hoyer D,Waeber C,Pazos A,Probst A,Palacios JM

更新日期：1988-03-10 00:00:00

abstract：:One of the clinical characteristics of psychogenic tremors (PT) is the disruption or transient cessation of tremor with distractive manoeuvres, including those involving the performance of voluntary movements with the contralateral hand. Seven patients with PT, 11 patients with Parkinson's disease (PD), 10 patients wi...

journal_title：Neuroscience letters

authors： Kumru H,Valls-Solé J,Valldeoriola F,Marti MJ,Sanegre MT,Tolosa E

更新日期：2004-11-11 00:00:00

abstract：:Recent studies have described the role of various regions of the neural cell adhesion molecule (NCAM) in cell-cell interactions. Monoclonal antibodies (L2/HNK-1) directed against a sulfated, glucuronic acid-containing, N-linked carbohydrate epitope have also been shown to inhibit NCAM-mediated neural cell adhesion. In...

journal_title：Neuroscience letters

authors： Cole GJ,Schachner M,Fliesler SJ

更新日期：1988-11-11 00:00:00

abstract：:HS-142-1 is a novel non-peptide antagonist for atrial natriuretic peptide (ANP) receptor. The effect of HS-142-1 on the cyclic GMP production elicited by natriuretic peptides in neuronal cell lines, PC12 and NG108-15 was examined. Natriuretic peptides such as ANP, brain natriuretic peptide (BNP), and C-type natriureti...

journal_title：Neuroscience letters

authors： Toki S,Morishita Y,Sano T,Matsuda Y

更新日期：1992-01-20 00:00:00

abstract：:Dysbindin gene (DTNBP1) has been associated with schizophrenia, but literature findings are inconsistent, and further analyses are required. This study is aimed to investigate if a set of DTNBP1 variations might influence clinic psychotic phenotype or treatment response in a sample of 240 Korean schizophrenic in-patie...

journal_title：Neuroscience letters

authors： Pae CU,Drago A,Kim JJ,Patkar AA,Jun TY,Lee C,Mandelli L,De Ronchi D,Paik IH,Serretti A

更新日期：2008-08-01 00:00:00

abstract：:The aim of the present study was to investigate the intrathecal (i.t.) action of a selective A1-adenosine receptor agonist, R-phenylisopropyl adenosine (R-PIA), on tactile withdrawal thresholds in a rat model of mononeuropathy produced by sciatic chronic constriction injury (CCI). An additional aim was to examine whet...

journal_title：Neuroscience letters

authors： Cui JG,Sollevi A,Linderoth B,Meyerson BA

更新日期：1997-02-28 00:00:00

abstract：:Both muscarinic and nicotinic acetylcholine (ACh) receptors are known to be present on the surface of lymphocytes. We have shown that variable amounts of ACh are detectable in the blood of various mammals including humans, and a major portion of blood ACh is localized in circulating mononuclear leukocytes in humans. I...

journal_title：Neuroscience letters

authors： Fujii T,Tajima S,Yamada S,Watanabe Y,Sato KZ,Matsui M,Misawa H,Kasahara T,Kawashima K

更新日期：1999-01-08 00:00:00

abstract：:Somatosensory integration is a critical cognitive function for human social interaction. Though somatosensory integration has been highly explored in cognitive studies; only a few studies have explored focal modulation of cortical excitability using a speech perception paradigm. In the current study, we aimed to inves...

journal_title：Neuroscience letters

authors： Lapenta OM,Fregni F,Oberman LM,Boggio PS

更新日期：2012-10-11 00:00:00

abstract：:Designer Receptors Exclusively Activated by Designer Drugs (DREADDs) are chemogenetic tools commonly-used to manipulate brain activity. The most widely-used synthetic DREADD ligand, clozapine-N-oxide (CNO), is back-metabolized to clozapine which can itself activate endogenous receptors. Studies in non-DREADD-expressin...

journal_title：Neuroscience letters

authors： Tran FH,Spears SL,Ahn KJ,Eisch AJ,Yun S

更新日期：2020-11-20 00:00:00

abstract：:Nogo-A has been identified as an inhibitory molecule to neurite outgrowth after injury in adult mammalian central nervous system (CNS). The C-terminal fragment of Nogo-A, Nogo-66, inhibits axonal regrowth through NgR1 signaling. Residues 1-32 of Nogo-66 cover two regions that contribute most affinity of Nogo-66 to NgR...

journal_title：Neuroscience letters

authors： Deng Q,Cai W,Li S,Su B

更新日期：2013-03-01 00:00:00

abstract：:Cholinergic projections originating in the basal forebrain (BF) play important roles in the heterosynaptic facilitation of synaptic strength in various sensory cortices, including the primary visual cortex (V1). Here, using urethane-anesthetized rats, we find that pairing burst stimulation of the BF with single pulse ...

journal_title：Neuroscience letters

authors： Gagolewicz PJ,Dringenberg HC

更新日期：2009-10-02 00:00:00

abstract：:Ultrasonic vocalization at 55kHz (55kHz-USVs) by rodents has been proposed to be a behavioral manifestation of affectively positive incentive motivation. To examine the extent to which 55kHz-USV emissions correlate with cocaine-induced locomotor activity, we measured cocaine-induced 55kHz-USVs and their relationship t...

journal_title：Neuroscience letters

authors： Mu P,Fuchs T,Saal DB,Sorg BA,Dong Y,Panksepp J

更新日期：2009-03-27 00:00:00

abstract：:Visual P300 responses were recorded by using checkerboard-type stimuli. (1) High amplitude P300-delta responses were visible even in single trial event-related potentials (ERPs). (2) The algorithm based on the 'delta response metric' provides an efficient selection criterion for evaluation of P300 single trials in ERP...

journal_title：Neuroscience letters

authors： Schürmann M,Başar-Eroglu C,Kolev V,Başar E

更新日期：1995-09-15 00:00:00

abstract：:The axonal efferents of neurons of the supraoptic nucleus area were studied by radioautography in the rat after discrete stereotaxic injections of [3H]leucine into this nucleus. Beside a densely labeled pathway running from the nucleus to the posterior pituitary through the internal median eminence, several of the vis...

journal_title：Neuroscience letters

authors： Alonso G,Szafarczyk A,Assenmacher I

更新日期：1986-05-23 00:00:00

abstract：:Using organotypic hippocampal slice cultures we have investigated the actions of Interleukin-1 (IL-1) in a number of injury paradigms. Low concentrations of IL-1 potentiated hypoxia-induced neurodegeneration whilst high concentrations had no effect. In contrast, higher concentrations of IL-1 were strongly neuroprotect...

journal_title：Neuroscience letters

authors： Pringle AK,Niyadurupola N,Johns P,Anthony DC,Iannotti F

更新日期：2001-06-01 00:00:00

abstract：:There is evidence indicating that the brain's dopaminergic system is involved in age-associated memory impairment. However, specific roles in this process for the different dopamine receptor subtypes have not been elucidated. The cAMP-response element binding protein (CREB) is one of the cellular molecules that have b...

journal_title：Neuroscience letters

authors： Xing B,Meng X,Wei S,Li S

更新日期：2010-09-13 00:00:00

abstract：:In order to study the rapidity of interaction between tetraethylammonium (TEA) and the delayed K+ channel of the mammalian brain neuron, TEA was applied to isolated rat hippocampal pyramidal neurons in a time-controlled sequence with a voltage step using a concentration clamp technique. TEA at a concentration of 30 mM...

journal_title：Neuroscience letters

authors： Oyama Y,Harata N,Akaike N

更新日期：1991-10-14 00:00:00

abstract：:The opioid peptide dynorphin A(1-8) (1 micron) increased acetylcholine release from the Torpedo electric organ by approximately twofold. This effect was reversed by the opiate antagonist naloxone. The effect of Dyn A(1-8) on acetylcholine release was found to vary in magnitude with the seasons of the year, with maxima...

journal_title：Neuroscience letters

authors： Oron L,Sarne Y,Michaelson DM

更新日期：1991-04-29 00:00:00

abstract：:The voltage dependency of the ON and the OFF components of transient amacrine cell responses was studied using two-electrode voltage-clamp and current-clamp techniques in the isolated retina of the carp. The two independent approaches gave similar data. When cells were voltage clamped near their resting potentials, bo...

journal_title：Neuroscience letters

authors： Djamgoz MB,Low JC,Saito T,Toyoda JI,Yamada M

更新日期：1996-08-23 00:00:00

abstract：:Our previous study demonstrated that successive electroacupuncture (EA) at ST36 acupoint reduces IgE production in BALB/c mice immunized with 2,4-dinitrophenylated keyhole limpet protein (DNP-KLH) by suppression of the Th2 cell lineage development. Here, we report that pretreatment of phentolamine (alpha-adrenoceptor ...

journal_title：Neuroscience letters

authors： Lee Y,Kim SK,Kim Y,Lee H,Shin MK,Hong MC,Min BI,Bae H

更新日期：2007-08-16 00:00:00

abstract：:In vivo L-band electron spin resonance (ESR) system was used to measure the decay of nitroxide radicals in the living rat cerebrum containing a cortical area with an iron-induced epileptogenic region. Carbamoyl-PROXYL (3-carbamoyl-2,2,5,5-tetramethyl-1-pyrrolinyloxy) was injected intraperitoneally. The decay of nitrox...

journal_title：Neuroscience letters

authors： Komatsu M,Hiramatsu M,Yokoyama H,Willmore LJ

更新日期：1996-03-01 00:00:00

abstract：:Previous studies using various excitatory amino acid antagonists have shown that synaptic transmission between the auditory nerve and the cochlear nucleus of chickens (nuc. magnocellularis; NM) is mediated by non-N-methyl-D-aspartate (non-NMDA) receptors. In the present study we have attempted to define the subclass o...

journal_title：Neuroscience letters

authors： Nemeth EF,Jackson H,Parks TN

更新日期：1985-09-06 00:00:00

abstract：:Monotherapy with antibodies to tumor necrosis factor-alpha (TNF) or interleukin-1 receptor 1 (IL-1R1) reduces hyperalgesia in an animal model of painful neuropathy. Here we investigated whether combined therapy with epineurial anti-TNF and anti-IL-1R1 antibodies produces a further advantage. C57BL/6 mice with a chroni...

journal_title：Neuroscience letters

authors： Schäfers M,Brinkhoff J,Neukirchen S,Marziniak M,Sommer C

更新日期：2001-09-14 00:00:00

abstract：:Imaging and lesion studies suggest that the cerebellum is involved in the self-generation of timed motor responses. Using repetitive transcranial magnetic stimulation (rTMS), we studied the effects of transient disruption of the lateral or medial cerebellum on a paced-finger-tapping task (PFT). Results show greater va...

journal_title：Neuroscience letters

authors： Théoret H,Haque J,Pascual-Leone A

更新日期：2001-06-22 00:00:00

abstract：:The excitability of the motoneuron (MN) pool in the resting state was compared between normal control subjects and patients with spasticity resulting from HTLV-I-associated myelopathy, using a new parameter, Hslp/Mslp, and the conventional parameters Hmax/Mmax and Hth/Mth. Differences in the excitability of the MN poo...

journal_title：Neuroscience letters

authors： Funase K,Higashi T,Yoshimura T,Imanaka K,Nishihira Y

更新日期：1996-01-19 00:00:00

abstract：:Neuraxial analgesia is often provided using a mixture of local anesthetics and opioids. This combination of agents provides better pain relief and is generally associated with fewer side effects than when either drug is given alone. Local anesthetics have been shown to alter signaling of other G protein-coupled recept...

journal_title：Neuroscience letters

authors： Komai H,McDowell TS

更新日期：2007-05-18 00:00:00

abstract：:Excitotoxin lesion of nucleus basalis with kainate or ibotenate results in degeneration of cholinergic neurones and a subsequent cholinergic deficit in cerebral cortex ipsilateral to the lesion. This lesion is accompanied by a massive increase in ornithine decarboxylase (ODC) activity in ipsilateral cortex, which was ...

journal_title：Neuroscience letters

authors： Wood H,de Belleroche J

更新日期：1990-03-26 00:00:00

abstract：:Recent evidence indicates that alterations in brain polyamine metabolism may be critical for nerve cell survival after a free radical initiated neurodegenerative process. It has been shown previously that A beta(1-42) and A beta(25-35) are toxic to neurons through a free radical dependent oxidative mechanism. Treatmen...

journal_title：Neuroscience letters

authors： Yatin SM,Yatin M,Aulick T,Ain KB,Butterfield DA

更新日期：1999-03-19 00:00:00