Kainic acid binding in human caudate nucleus: effect of Huntington's disease.

abstract：:In the hypothalamus of androgen-insensitive testicular feminized (Tfm) mice the normal pattern of immunohistochemical staining for glial fibrillary acidic protein (GFAP) is markedly different from normal. Along the borders of the third ventricle and in the dorsomedial and arcuate nuclei, the numbers of stained astrocy...

journal_title：Neuroscience letters

authors： McQueen JK,Wright AK,Arbuthnott GW,Fink G

更新日期：1990-10-02 00:00:00

abstract：:Various tracer substances were injected into the spinal cord, the dorsal column nuclei, the trigeminal nuclear complex and the somatosensory cortex in Madagascan hedgehog tenrecs. With the exception of the cases injected exclusively into the spinal cord all injections gave rise to sparse, but distinct anterograde proj...

journal_title：Neuroscience letters

authors： Wolff A,Künzle H

更新日期：1997-01-17 00:00:00

abstract：:The interaction of NMDA receptor (NMDAR) activation and other mechanisms regulating neuronal excitability have not been thoroughly described. While excess activation of NMDARs results in excitotoxicity, partial activation of NMDARs by d-cycloserine (DCS) is nootropic, enhancing both acquisition and extinction of memor...

journal_title：Neuroscience letters

authors： Donzis EJ,Thompson LT

更新日期：2014-06-13 00:00:00

abstract：:The content of the neurosteroids, dehydroepiandrosterone (DHEA) in the brain decreases with aging. Also the oxidative energy metabolism is known to decrease with aging. Hence we examined the effects of treatment with DHEA (0.2 or 1.0 mg/kg body weight for 7 days) on oxidative energy metabolism in brain mitochondria fr...

journal_title：Neuroscience letters

authors： Patel MA,Katyare SS

更新日期：2006-07-10 00:00:00

abstract：:Exposure to manganese in an industrial or clinical setting can lead to manganism, a neurological disorder with similarities to Parkinson's disease. Although the pathogenetic basis of this disorder is unclear, studies indicate this metal is highly accumulated in astrocytes, suggesting an involvement of these glial cell...

journal_title：Neuroscience letters

authors： Hazell AS,Normandin L,Norenberg MD,Kennedy G,Yi JH

更新日期：2006-04-03 00:00:00

abstract：:Loss of ganglion cells is a common and irreversible complication of hair cell loss in the cochlea. Gene transfer could potentially be used to prevent this neuronal degeneration and other pathologies in the cochlea. Human adenoviruses should provide a feasible gene transfer vehicle for transducing the quiescent cochlea...

journal_title：Neuroscience letters

authors： Raphael Y,Frisancho JC,Roessler BJ

更新日期：1996-03-29 00:00:00

abstract：:The effects of i.v. administration of a nitric oxide (NO) synthase inhibitor, L-NG-nitroarginine (L-NOArg), on the increase in cerebral cortical blood flow (cortical BF), following either electrical stimulation of the nucleus basalis of Meynert (NBM), whose cholinergic fibers project to the cortex, or hypercapnia with...

journal_title：Neuroscience letters

authors： Adachi T,Inanami O,Sato A

更新日期：1992-05-25 00:00:00

abstract：:FOXP2, the first gene known to be involved in the development of speech and language, can be considered to be, a priori, a candidate gene in schizophrenia, given the mounting evidence that the underlying core deficit in this disease could be a failure of structures relevant to normal language processing. To investigat...

journal_title：Neuroscience letters

authors： Španiel F,Horáček J,Tintěra J,Ibrahim I,Novák T,Čermák J,Klírová M,Höschl C

更新日期：2011-04-15 00:00:00

abstract：:Sexual receptivity was suppressed in female rats immediately after the male had ejaculated. The inhibition was prevented by intravaginal injection of naloxone (100 micrograms) before testing and intravaginal injection of beta-endorphin (1.0 micrograms) inhibited sexual behavior in female rats in a manner comparable to...

journal_title：Neuroscience letters

authors： Forsberg G,Bednar I,Eneroth P,Södersten P

更新日期：1990-07-17 00:00:00

abstract：:Self-initiated leg movement in standing humans is preceded by a medio-lateral preparatory balance adjustment (PBA); however, such preparatory balance control is often absent in reflex-like stepping responses evoked by whole-body instability. The presence or absence of the PBA may reflect a task-dependent modulation of...

journal_title：Neuroscience letters

authors： McIlroy WE,Bent LR,Potvin JR,Brooke JD,Maki BE

更新日期：1999-06-04 00:00:00

abstract：:Traumatic spinal cord injury (SCI) is a devastating condition of CNS which leads to loss of sensory as well as motor functions. Secondary damage after SCI initiates cascade of events that creates an inhibitory milieu for axonal growth and repair. Combinatorial therapies are the hope to attenuate secondary injury progr...

journal_title：Neuroscience letters

authors： Bhattacharyya S,Dinda A,Vishnubhatla S,Anwar MF,Jain S

更新日期：2021-01-10 00:00:00

abstract：:The magnetic cell sorter (MACS) technique was applied to isolate retinal ganglion cells (RGCs) for culture. RGCs were labeled retrogradely with 1.1'-dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate (Dil). Subsequently retinal cell suspensions were incubated with biotinylated anti-rat Thy-1 antibody and MA...

journal_title：Neuroscience letters

authors： Shoge K,Mishima HK,Mukai S,Shinya M,Ishihara K,Kanno M,Sasa M

更新日期：1999-01-08 00:00:00

abstract：:In the presence of atropine electrical transmural stimulation (using repetitive volleys, e.g. 3 pulses at 50 Hz applied every 4 s) of full thickness longitudinal strips of guinea-pig ileum produced non-cholinergic excitatory junction potentials (EJPs) and inhibitory junction potentials (IJPs) in the circular muscle la...

journal_title：Neuroscience letters

authors： Taylor GS,Bywater RA

更新日期：1986-01-02 00:00:00

abstract：:The effect of partial isomerization of dietary alpha-linolenic acid on the monoaminergic neurotransmitters in piglets was studied. After feeding the animals for 14 days with diets containing or not trans alpha-linolenic acid, neurotransmitters related to the monoaminergic function were quantified in the frontal cortex...

journal_title：Neuroscience letters

authors： Acar N,Chardigny JM,Berdeaux O,Almanza S,Sébédio JL

更新日期：2002-10-18 00:00:00

abstract：:The influence of the medial prefrontal cortex (PFC) on mesolimbic dopamine activity was studied with electrophysiological techniques and in vivo voltammetry in the chloral hydrate-anesthetized male rat. Glutamate injected into the PFC selectively increased burst firing of single dopamine cells in the ventral tegmental...

journal_title：Neuroscience letters

authors： Murase S,Grenhoff J,Chouvet G,Gonon FG,Svensson TH

更新日期：1993-07-09 00:00:00

abstract：:We used the mismatch negativity event-related potential to examine how spatial location and feature variation affect the capacity of the auditory system to automatically respond to pairs of rapid (180 ms apart) acoustic changes within a single tone. When a tone first deviated from a standard tone in source location an...

journal_title：Neuroscience letters

authors： Deouell LY,Karns CM,Harrison TB,Knight RT

更新日期：2003-01-02 00:00:00

abstract：:We describe the incidence of gamma-aminobutyric acid (GABA)ergic neurons after post-embedding immunocytochemistry on semithin sections of the claustrum, putamen and lateral, dorsal and medial cortical areas. Twelve percent of the neurons counted in the claustrum of 11 rabbits were GABAergic. This incidence was signifi...

journal_title：Neuroscience letters

authors： Gómez-Urquijo SM,Gutiérrez-Ibarluzea I,Bueno-López JL,Reblet C

更新日期：2000-03-24 00:00:00

abstract：:The distribution of Purkinje cells projecting to the descending vestibular nucleus was studied in lobule IX (uvula) of the cat by the retrograde wheat germ agglutinin-horseradish peroxidase method. In the transverse plane labeled Purkinje cells were seen diffusely within 1.0 mm from the midline and densely for 250-500...

journal_title：Neuroscience letters

authors： Matsushita M,Wang CL

更新日期：1986-05-23 00:00:00

abstract：:Repeated stress triggers a wide range of adaptive changes in the central nervous system including the elevation of serotonin (5-HT) metabolism and an increased susceptibility to affective disorders. To begin to examine whether these changes are mediated by alterations in gene expression for tryptophan hydroxylase (TPH...

journal_title：Neuroscience letters

authors： Chamas F,Serova L,Sabban EL

更新日期：1999-06-04 00:00:00

abstract：:Although first mentions about calcium disturbances in psychiatric diseases appeared more than 30 years ago, the most recent genomic and proteomic findings confirmed a significant role of Ca2+ and Ca2+-regulated pathways in development of neuropathological processes, including bipolar disorder and schizophrenia. Moreov...

journal_title：Neuroscience letters

authors： Lisek M,Boczek T,Zylinska L

更新日期：2018-01-10 00:00:00

abstract：:Febrile seizures (FS) are generally defined as seizures taking place during fever. Long-term prognosis, including development of epilepsy and malformation of cognitive function, has been demonstrated after infantile FS. However, the mechanism that triggers seizures in hyperthermic environment is still unclear. We here...

journal_title：Neuroscience letters

authors： Feng B,Tang YS,Chen B,Dai YJ,Xu CL,Xu ZH,Zhang XN,Zhang SH,Hu WW,Chen Z

更新日期：2014-10-03 00:00:00

abstract：:Cerebral perfusion is important in older adults as it is linked to cognitive declines. Physical activity can improve blood flow in the body but little is known about the relationship between physical activity and cerebral perfusion in older adults. In particular, no study has investigated the relation between strength...

journal_title：Neuroscience letters

authors： Xu X,Jerskey BA,Cote DM,Walsh EG,Hassenstab JJ,Ladino ME,Clark US,Labbe DR,Gunstad JJ,Poppas A,Cohen RA,Hoge RD,Sweet LH

更新日期：2014-02-07 00:00:00

abstract：:Spinocerebellar ataxias (SCAs) are a group of clinically and genetically heterogeneous neurological diseases. The expansion of unstable microsatellite repeats has been identified as the underlying pathogenic cause of 10 subtypes of autosomal dominant SCAs. The aetiology of sporadic SCA is unknown. The aim of this stud...

journal_title：Neuroscience letters

authors： Majounie E,Wardle M,Muzaimi M,Cross WC,Robertson NP,Williams NM,Morris HR

更新日期：2007-12-11 00:00:00

abstract：:Thyroid hormone metabolism was investigated in the frontal cortex and amygdala in groups of rats either 'behaviorally dependent' on ethanol or chronically exposed to ethanol, but not 'dependent'. The activities of the 5'II deiodinase isoenzyme, which catalyzes the deiodination of thyroxine (T4) to the active metabolit...

journal_title：Neuroscience letters

authors： Baumgartner A,Eravci M,Pinna G,Hiedra L,Prengel H,Brödel O,Meinhold H

更新日期：1997-05-09 00:00:00

abstract：:Central administration of colchicine causes accumulation of catecholamines in nerve cell bodies and enhances their visualisation in the rat brain by the formaldehyde-glutaraldehyde (FAGLU) histofluorescence method. The detection of catecholamine-containing nerve cells by the FAGLU method was considerably improved in r...

journal_title：Neuroscience letters

authors： Howe PR,Rogers PF,Blessing WW

更新日期：1984-12-21 00:00:00

abstract：:The role of nitric oxide in cerebral insults remains controversial. While numerous studies have used models of ischaemia and hypoxia, few have examined nitric oxide in the kainate model of excitotoxicity. Kainate (10 mg/kg) was administered to rats via the intraperitoneal (i.p.) route to induce submaximal damage to th...

journal_title：Neuroscience letters

authors： Jones PA,Smith RA,Stone TW

更新日期：1998-06-19 00:00:00

abstract：:Reflex micturition was evoked in both non-immobilized (n = 5) and immobilized (n = 5) decerebrate cats by filling the bladder with physiological saline. Intracellular recordings were made from pudendal motoneurons (PU-MNs; n = 14) throughout the periods of before, during and after reflex micturition. The changes in th...

journal_title：Neuroscience letters

authors： Shimoda N,Takakusaki K,Nishizawa O,Tsuchida S,Mori S

更新日期：1992-02-03 00:00:00

abstract：:Horseradish peroxidase (HRP) was injected into the thalamic ventral tier of squirrel monkey and the brainstem was examined for the presence of HRP-reactive cells in the external cuneate nucleus (ECN), nuclei Z and X, and the mesencephalic nucleus of the trigeminal nerve (MNV). Results indicate that the ECN, Z and X ha...

journal_title：Neuroscience letters

authors： Pearson JC,Garfunkel DA

更新日期：1983-10-31 00:00:00

abstract：:Xenopus oocytes were injected with mRNA from adult or neonatal rat spinal cord, or from adult cerebral cortex, and examined electrophysiologically to measure currents elicited by various receptor agonists. The mRNAs induced the oocytes to acquire similar types of amino acid receptors, albeit with different potencies. ...

journal_title：Neuroscience letters

authors： Akagi H,Miledi R

更新日期：1988-12-19 00:00:00

abstract：:An increasing number of studies support the presence of stem-like cells in human malignancies. These cells are primarily responsible for tumor initiation and thus considered as a potential target to eradicate tumors. CD133 has been identified as an important cell surface marker to enrich the stem-like population in va...

journal_title：Neuroscience letters

authors： Dong L,Qi N,Ge RM,Cao CL,Lan F,Shen L

更新日期：2010-11-05 00:00:00