Visualisation of catecholamine-fluorescent nerve cell bodies in the rat brain after colchicine treatment.

abstract：:This study was designed toinvestigate the efficacy of adenovirus vector-mediated brain-derived neurotrophic factor (BDNF) ex vivo gene transfer to human umbilical cord blood-derived mesenchymal stem cells (UCB-MSCs) in a rat sciatic nerve crush injury model. BDNF protein and mRNA expression after infection was checked...

journal_title：Neuroscience letters

authors： Hei WH,Almansoori AA,Sung MA,Ju KW,Seo N,Lee SH,Kim BJ,Kim SM,Jahng JW,He H,Lee JH

更新日期：2017-03-16 00:00:00

abstract：:The present experiment investigated cortical responses of native Italian subjects during reading of short sentences including semantic or morphosyntactic violations. Given the specificity of the Italian language in which the sequencing of words is relatively more free than in English or other languages, we investigate...

journal_title：Neuroscience letters

authors： Angrilli A,Penolazzi B,Vespignani F,De Vincenzi M,Job R,Ciccarelli L,Palomba D,Stegagno L

更新日期：2002-03-29 00:00:00

abstract：:Cytochrome c oxidase (COX) is a key mitochondrial enzyme that catalyzes electron transfer at the terminal stage of respiratory chain and is composed of multisubunits. We hypothesize that ethanol withdrawal (EW) impairs the activity of COX and estrogen deprivation exacerbates this problem. Five-month-old ovariectomized...

journal_title：Neuroscience letters

authors： Jung ME,Agarwal R,Simpkins JW

更新日期：2007-04-12 00:00:00

abstract：:The ganglion cell density of the quail's retina was studied in sections and whole mounts. Two regions of high ganglion cell density were found, corresponding to an afoveate area centralis and an area dorsalis. Oil droplets were found to be isotropically distributed throughout the retina. It is proposed that the signif...

journal_title：Neuroscience letters

authors： Budnik V,Mpodozis J,Varela FJ,Maturana HR

更新日期：1984-09-28 00:00:00

abstract：:Large-conductance calcium-activated potassium channels (BK channels) have been suggested to play a substantial role in synaptic transmission in the spinal cord dorsal horn. In the present experiments, we attempted to clarify the physiological significance of BK channels in the modulation of synaptic transmission in th...

journal_title：Neuroscience letters

authors： Furukawa N,Takasusuki T,Fukushima T,Hori Y

更新日期：2008-10-17 00:00:00

abstract：:The content of the neurosteroids, dehydroepiandrosterone (DHEA) in the brain decreases with aging. Also the oxidative energy metabolism is known to decrease with aging. Hence we examined the effects of treatment with DHEA (0.2 or 1.0 mg/kg body weight for 7 days) on oxidative energy metabolism in brain mitochondria fr...

journal_title：Neuroscience letters

authors： Patel MA,Katyare SS

更新日期：2006-07-10 00:00:00

abstract：:Although minocycline has been generally thought to have neuroprotective properties, the neuroprotective role of minocycline has not been investigated in the animal model of epilepsy. In this study, we investigated whether minocycline is neuroprotective against kainic acid (KA)-induced cell death through the caspase-de...

journal_title：Neuroscience letters

authors： Heo K,Cho YJ,Cho KJ,Kim HW,Kim HJ,Shin HY,Lee BI,Kim GW

更新日期：2006-05-08 00:00:00

abstract：:The purpose of this study was to measure the average anterior commissure (AC) volume of normal subjects in their 20s or 40s and to determine the effects of gender and age on AC volume. Magnetic resonance brain images were obtained for 93 people in their 20s (46 men, 47 women) and 87 in their 40s (36 men, 51 women). To...

journal_title：Neuroscience letters

authors： Choi MH,Kim JH,Yeon HW,Choi JS,Park JY,Jun JH,Lee BY,Kim HJ,Tack GR,Chung SC

更新日期：2011-08-15 00:00:00

abstract：:Four substance P (SP) antagonists were tested on anaesthetized rats, by injecting 8 microgram amounts into the spinal cord (T8-T9), and by observing their effects on the hypothalamo-neurohypophysial responses to a presumably painful stimulus, the superfusion of the hepatic portal vein with 1 microM bradykinin. Only tw...

journal_title：Neuroscience letters

authors： Stoppini L,Baertschi AJ,Mathison R,Barja F

更新日期：1983-06-30 00:00:00

abstract：:Postmitotic neurons were generated from the human NT2 teratocarcinoma cell line in a novel cell aggregate differentiation procedure. The NT2 model neurons express punctate immunoreactivity for synapsin and for cell markers related to GABAergic and glutamatergic neurotransmission. Using the outside-out patch-clamp conf...

journal_title：Neuroscience letters

authors： Podrygajlo G,Song Y,Schlesinger F,Krampfl K,Bicker G

更新日期：2010-01-14 00:00:00

abstract：:The aim of this study was to investigate trigeminal nerve involvement in patients with peripheral facial palsy. In total, 25 patients with facial nerve palsy and 19 controls were tested by electrophysiological methods regarding their facial and trigeminal nerve functions within 1 month after disease onset. The presenc...

journal_title：Neuroscience letters

authors： Uluduz D,Kiziltan ME,Akalin MA

更新日期：2010-07-26 00:00:00

abstract：:It has been shown that orexin neuropeptides contribute to morphine-induced physical dependence. The locus coeruleus (LC), which receives a dense extra-hypothalamic orexinergic projection, is a key brain region implicated in the expression of somatic signs of morphine withdrawal syndrome. The aim of the present study i...

journal_title：Neuroscience letters

authors： Azizi H,Mirnajafi-Zadeh J,Rohampour K,Semnanian S

更新日期：2010-10-04 00:00:00

abstract：:The three tracers horseradish peroxidase (HRP), 4',6-diamidino-2-phenylindol-2HCl (DAPI) and Fast Blue (FB) differ in retrograde labeling of striato-nigral neurons. After a 24 h survival, injection of DAPI into the ventral tegmentum labeled numerous cells throughout the neostriatum, whereas an identical amount of HRP ...

journal_title：Neuroscience letters

authors： Frotscher M,Wagner A,Misgeld U

更新日期：1983-07-29 00:00:00

abstract：:Conduction velocities of antidromically evoked impulses along the goldfish Mauthner axon were found to be inversely correlated with body length. To test the hypothesis that such a relation is accompanied by a reduction in axonal diameter with increasing fish size, Mauthner axon diameters were measured. A parabolic rel...

journal_title：Neuroscience letters

authors： Funch PG,Kinsman SL,Faber DS,Koenig E,Zottoli SJ

更新日期：1981-12-11 00:00:00

abstract：:Studies were performed to bring out a serotoninergic involvement in physostigmine tremor, hitherto known to be working via the cholinergic system. 5-Hydroxytryptamine (5-HT) was estimated fluorimetrically after isolation on Sephadex G-10 and acetylcholinesterase (AChE) was assayed spectrophotometrically. The dose-depe...

journal_title：Neuroscience letters

authors： Mohanakumar KP,Mitra N,Ganguly DK

更新日期：1990-11-27 00:00:00

abstract：:The function of acetylcholine (ACh) in the mammalian pineal gland is unknown. To test the hypothesis that ACh exerts a modulatory role in this organ, in the present study electrophysiogical multiunit recordings were carried out in ex-vivo rat pineal glands superfused with different drugs. It was found that ACh (10(-7)...

journal_title：Neuroscience letters

authors： Schenda J,Vollrath L

更新日期：1998-09-18 00:00:00

abstract：:Pharmacological blocking agents were used to assess the contributions of different K(+)-currents to spike-repolarization and early spike-afterhyperpolarization recorded in dissociated, tissue-cultured rat superior cervical sympathetic neurones using both patch-clamp and impalement microelectrode techniques. Effects of...

journal_title：Neuroscience letters

authors： Marsh SJ,Brown DA

更新日期：1991-12-09 00:00:00

abstract：:Galanin- and bethanechol-activated whole cell currents were studied in dissociated mudpuppy parasympathetic neurons kept in 12.5 mM KCl. The bethanechol-induced current was reduced when generated during a galanin-induced current. The galanin and bethanechol currents reversed at -45 mV and exhibited inward rectificatio...

journal_title：Neuroscience letters

authors： Parsons RL,Merriam LA

更新日期：1992-06-08 00:00:00

abstract：:The effect of the neuropeptide, substance P, on the transport of D-[(3)H]aspartate into rat striatal synaptosomes was studied. Almost 90% of the total transport of D-[(3)H]aspartate was sodium-dependent and the maximum rate (V(max)) of this transport was increased by 34% of control by 2.5 nM substance P (EC(50)=0.52 n...

journal_title：Neuroscience letters

authors： Healy J,Downes A,McBean GJ

更新日期：2000-08-25 00:00:00

abstract：:Cerebral ischemia induces rapid efflux of glutamate into the extracellular space contributing to excessive activation of glutamate receptors in postsynaptic cells, particularly N-methyl-D-aspartate (NMDA) receptors, which triggers the neuron lesion through calcium overload. Our studies indicated that cerebral ischemia...

journal_title：Neuroscience letters

authors： Guo J,Meng F,Fu X,Song B,Yan X,Zhang G

更新日期：2004-01-30 00:00:00

abstract：:Following peripheral nerve section, the cell body and proximal axon undergo various physiological and morphological changes which may be associated with regrowth. We found that axotomy reduced the amplitude and duration of the afterhyperpolarization (AHP) of the action potential (AP) of bullfrog sympathetic neurones. ...

journal_title：Neuroscience letters

authors： Kelly ME,Gordon T,Shapiro J,Smith PA

更新日期：1986-06-18 00:00:00

abstract：:Long-term potentiation (LTP) of perforant-path dentate granule cell synapses, in awake rats, was followed by a time-dependent expression of brain-derived neurotrophic factor (BDNF) mRNA in dentate granule cells. This BDNF expression was blocked by the N-methyl-D-aspartate (NMDA) antagonist dizocilpine maleate (MK-801)...

journal_title：Neuroscience letters

authors： Dragunow M,Beilharz E,Mason B,Lawlor P,Abraham W,Gluckman P

更新日期：1993-10-01 00:00:00

abstract：:Effects of anxiety on perceptual-motor organisation of rhythmical forearm movements were examined using an interrupted time series design with staggered baselines. Participants were exposed to repeated baseline sessions interrupted with two anxiety-inducing sessions. Results showed that under moderate levels of anxiet...

journal_title：Neuroscience letters

authors： Court ML,Bennett SJ,Williams AM,Davids K

更新日期：2005-08-12 00:00:00

abstract：:We investigated whether the presence of unimodal or bimodal (synchronous) distractors would affect temporal order judgments (TOJs) for pairs of asynchronous audiovisual target stimuli. Participants made unspeeded TOJs regarding which of a pair of auditory and visual stimuli, presented at different stimulus onset async...

journal_title：Neuroscience letters

authors： Vatakis A,Spence C

更新日期：2006-11-06 00:00:00

abstract：:To determine whether mutations in the coding region of the alpha-synuclein gene are relevant in cases of multiple system atrophy (MSA), detailed nucleotide sequence analysis of the alpha-synuclein gene was performed using total RNA obtained from autopsied brain specimens of 11 pathologically confirmed cases of MSA. Th...

journal_title：Neuroscience letters

authors： Ozawa T,Takano H,Onodera O,Kobayashi H,Ikeuchi T,Koide R,Okuizumi K,Shimohata T,Wakabayashi K,Takahashi H,Tsuji S

更新日期：1999-07-30 00:00:00

abstract：:Astrocytes have been implicated in axon guidance and synaptic regeneration in the retina and these processes involve activation of the high affinity nerve growth factor receptor, known as the tyrosine kinase A (TrkA) receptor. The purpose of the present study was to characterize the expression of TrkA in astrocytes of...

journal_title：Neuroscience letters

authors： Ruiz-Ederra J,Hitchcock PF,Vecino E

更新日期：2003-02-13 00:00:00

abstract：:The primary component of amyloid deposits found in the brains of patients with Alzheimer's disease is the beta-amyloid protein, a derivative of a much larger precursor protein (beta PP). We have previously reported that overexpression of carboxyl (COOH)-terminal fragments of beta PP from an integrated DNA construct le...

journal_title：Neuroscience letters

authors： Fukuchi K,Sopher B,Furlong CE,Smith AC,Dang N,Martin GM

更新日期：1993-05-14 00:00:00

abstract：:Vascular cognitive impairment (VCI) is the second most common cause of dementia after Alzheimer's disease, and the cognitive impairment is one of the common effects of VCI. Unfortunately, it lacks effective therapeutic treatments at present. In our previous study, environmental enrichment (EE), as an early interventio...

journal_title：Neuroscience letters

authors： Xu L,Qu C,Qu C,Shen J,Song H,Li Y,Li T,Zheng J,Zhang J

更新日期：2020-11-20 00:00:00

abstract：:Previous neuroimaging studies raised the hypothesis that enhanced activity in the ipsilateral motor cortex (M1) plays a contributing role in the compensation for the motor deficits resulting from a spinal cord injury (SCI). However, it is still unknown whether the activity in the ipsilateral M1 directly contributes to...

journal_title：Neuroscience letters

authors： Nardone R,Höller Y,Höller P,Thon N,Thomschewski A,Brigo F,Trinka E

更新日期：2013-09-27 00:00:00

abstract：:To clarify the details of the involvement of Ca(2+)-calmodulin in gating of C1-channels, effects of a novel calmodulin-dependent protein kinase II (CaMK II) inhibitor, KN-62, on C1-current and C1-efflux induced by serotonin (5-HT) were investigated in Xenopus oocyte injected with rat brain mRNA. 5-HT evoked inward cur...

journal_title：Neuroscience letters

authors： Tohda M,Nakamura J,Hidaka H,Nomura Y

更新日期：1991-08-05 00:00:00