Calcium as a Trojan horse in mental diseases-The role of PMCA and PMCA-interacting proteins in bipolar disorder and schizophrenia.

abstract：:In order to determine if an event-related brain potential (ERP) effect described for syntactic violations (P600/SPS) varies with the amount of reprocessing entailed by a violation, number incongruencies were presented either within simple declarative or within subordinate clauses. ERPs were recorded while 12 German su...

journal_title：Neuroscience letters

authors： Münte TF,Szentkuti A,Wieringa BM,Matzke M,Johannes S

更新日期：1997-10-17 00:00:00

abstract：:The aim of the present study was to examine the patterns of activation of the P600 waveform of the event-related potentials (ERP), applying principal component analysis (PCA) and repeated measures ANOVA, and whether these patterns are RF and gender dependent. The ERPs of thirty-nine healthy subjects (20 male and 19 fe...

journal_title：Neuroscience letters

authors： Maganioti AE,Hountala CD,Papageorgiou CC,Kyprianou MA,Rabavilas AD,Capsalis CN

更新日期：2010-06-30 00:00:00

abstract：:Protein profiling of cerebrospinal fluid in Guillain-Barrè syndrome (GBS), an acute and immune-mediated disease affecting the peripheral nervous system, was performed by two-dimensional electrophoresis. Significant modulated spots in GBS patients vs. control groups (a group of multiple sclerosis patients and one of he...

journal_title：Neuroscience letters

authors： D'Aguanno S,Franciotta D,Lupisella S,Barassi A,Pieragostino D,Lugaresi A,Centonze D,D'Eril GM,Bernardini S,Federici G,Urbani A

更新日期：2010-11-12 00:00:00

abstract：:The effects of methamphetamine (MAP) administration on neurotensin-like immunoreactivity (NTLI) were investigated in the rat brain. A single administration of MAP induced dose-dependent and reversible increases in NTLI in the caudate-putamen, limbic forebrain and midbrain. NTLI in the caudate-putamen, limbic forebrain...

journal_title：Neuroscience letters

authors： Wachi M,Okuda M,Togashi S,Miyashita O,Wakahoi T

更新日期：1987-07-22 00:00:00

abstract：:In striatal neurons in primary culture quisqualate potently stimulated the formation of inositol phosphates via a metabotropic receptor we recently termed Qp in order to distinguish it from the classical ionotropic quisqualate receptor termed Qi. Here we show that 10 microM of quisqualate activated in a rapid and tran...

journal_title：Neuroscience letters

authors： Manzoni OJ,Finiels-Marlier F,Sassetti I,Blockaert J,le Peuch C,Sladeczek FA

更新日期：1990-02-05 00:00:00

abstract：:Antibodies to fibronectin (Fn) bind not only the basal lamina in Alzheimer's disease brain, but also crystal-like formations in the grey matter, senile plaques, a subset of neuronal perikarya, and large highly processed stellate formations which were both neurofilament and glial fibrillary acidic protein (GFAP) negati...

journal_title：Neuroscience letters

authors： Howard J,Pilkington GJ

更新日期：1990-10-02 00:00:00

abstract：:Bilateral complete transection of the fimbria-fornix causes a significant increase in nerve growth factor (NGF) content both in the septum and hippocampus of the adult rat as measured by a sensitive immunoassay 7 days after lesioning. The finding, that elevation of NGF in septum (250%) was much more pronounced than th...

journal_title：Neuroscience letters

authors： Weskamp G,Gasser UE,Dravid AR,Otten U

更新日期：1986-09-25 00:00:00

abstract：:The existence of neurons expressing preprogalanin mRNA in the monkey hippocampal formation was demonstrated using in situ hybridization of a radio-labelled cRNA probe transcribed from human preprogalanin cDNA. Specific hybridization occurred in neurons of the hilus of the dentate gyrus, fields CA1-3 in Ammon's horn, s...

journal_title：Neuroscience letters

authors： Evans HF,Huntley GW,Morrison JH,Shine J,Paxinos G

更新日期：1992-11-09 00:00:00

abstract：:Push-pull cannulae were acutely positioned through previously implanted guides in the globus pallidus of unanesthetized freely moving cats and rats. During slow-flow perfusions, enkephalin release was detected in resting conditions and increased more than 3-fold when both 50 mM K+ and 1.8 mM Ca2+ were present in the p...

journal_title：Neuroscience letters

authors： Bayon A,Shoemaker WJ,Lugo L,Azad R,Ling N,Drucker-Colin RR,Bloom FE

更新日期：1981-06-12 00:00:00

abstract：:Cholecystokinin octapeptide (CCK-8) is the most potent endogenous anti-opioid peptide and regulates a variety of physiological processes. In our previous study, we found that exogenous CCK-8 attenuated naloxone-induced withdrawal symptoms, but the possible regulative effects of CCK-8 on the rewarding effects of morphi...

journal_title：Neuroscience letters

authors： Wen D,Cong B,Ma C,Yang S,Yu H,Ni Z,Li S

更新日期：2012-02-21 00:00:00

abstract：:The medial septal area (MSA) contains cholinergic and GABAergic neurons that send projections to the hippocampus. These neurons have both cholinergic and GABAergic receptors. This study was designed to determine the effects of intraseptal infusions of cholinergic and GABAergic drugs, which alter mnemonic processes, on...

journal_title：Neuroscience letters

authors： Gorman LK,Pang K,Frick KM,Givens B,Olton DS

更新日期：1994-01-31 00:00:00

abstract：:Cytoplasmic acidification in taste receptor cells is thought to be involved, at least in part, in acid taste transduction. Since in taste buds about 20% of the receptor cells are electrically coupled, we have tested whether reduction in intracellular pH affects these lateral synaptic interactions. By applying the patc...

journal_title：Neuroscience letters

authors： Bigiani A,Roper SD

更新日期：1994-08-01 00:00:00

abstract：:The relationship between pain severity and the extent of injury to a peripheral nerve remains elusive. In this study, we compared the pain behavior resulting from partial (1/3-1/2 thickness) and full L5 spinal nerve ligation (SNL) in rats. The decrease in paw withdrawal threshold (PWT) to mechanical stimuli in the hin...

journal_title：Neuroscience letters

authors： Guan Y,Yuan F,Carteret AF,Raja SN

更新日期：2010-02-26 00:00:00

abstract：:Alpha-tocopherol and its derivatives have been shown to be effective in reducing cerebral ischemia-induced brain damage. However, the effects of other vitamin E isoforms have not been characterized. In the present study, we investigated the effects of six different isoforms of vitamin E on the ischemic brain damage in...

journal_title：Neuroscience letters

authors： Mishima K,Tanaka T,Pu F,Egashira N,Iwasaki K,Hidaka R,Matsunaga K,Takata J,Karube Y,Fujiwara M

更新日期：2003-01-30 00:00:00

abstract：:The effect of dexmedetomidine, a selective alpha2-adrenoreceptor agonist and neuroprotective agent on the expression of immediate early genes and heat shock protein hsp70, was studied using quantitative in situ hybridization in a global ischemia model. At the dose previously shown to be neuroprotective dexmedetomidine...

journal_title：Neuroscience letters

authors： Wittner M,Sivenius J,Koistinaho J

更新日期：1997-08-29 00:00:00

abstract：:Experiments were performed to test several predictions of the hypothesis that activity pattern-dependent changes in intracellular free calcium concentration ([Ca2+]i) might play a role in the translation of altered patterns of neuronal activity into changes in neurotransmitter gene expression. It was shown that (1) th...

journal_title：Neuroscience letters

authors： Hodaie M,Jeevaratnam P,Salter MW,Roach A

更新日期：1995-02-13 00:00:00

abstract：:The use of the cobalt technique is limited by the fact that cobaltous ions travel within axons for a shorter distance than do other intracellular markers. In the present experiments different organic cobaltous complexes were tested in the rat's sciatic nerve. Cobaltous complexes containing ornithine, threonine, lysine...

journal_title：Neuroscience letters

authors： Gallyas F,Lénárd L,Lázár G

更新日期：1978-09-01 00:00:00

abstract：:MicroRNAs (miRNAs) are small noncoding RNAs that function as tumor suppressors or oncogenes. MicroRNA-107 (miR-107), a transcriptional target of p53, is deregulated in many cancer cell lines. Here, we showed that miR-107 is down-regulated in glioma tissues and cell lines, in particular, p53-mutated U251 and A172. Tran...

journal_title：Neuroscience letters

authors： Chen L,Zhang R,Li P,Liu Y,Qin K,Fa ZQ,Liu YJ,Ke YQ,Jiang XD

更新日期：2013-02-08 00:00:00

abstract：:Sex differences in basal extracellular striatal dopamine concentrations in gonadectomized male and female rats have been reported previously. In the current experiment, estrous cycle-dependent variation, sex differences and the effect of gonadectomy on extracellular striatal dopamine concentrations were determined usi...

journal_title：Neuroscience letters

authors： Xiao L,Becker JB

更新日期：1994-10-24 00:00:00

abstract：:NMDA receptors play important roles in brain formation by taking part in synaptogenesis and apoptosis. In the present study, the expression of NMDA receptors was analyzed in a neural stem cell line, MSP-1, which lacks p53. p53 is a transcription factor involved in excitotoxic neuronal apoptosis. It is quite likely tha...

journal_title：Neuroscience letters

authors： Yamada K,Hisatsune T,Uchino S,Nakamura T,Kudo Y,Kaminogawa S

更新日期：1999-04-02 00:00:00

abstract：:In untreated patients with Parkinson's disease (PD), the total (free and conjugated) serotonin (5-HT) and dopamine (DA) concentrations in the cerebrospinal fluid decreased significantly. While the 5-HT concentration displayed a non-significant trend of negative correlation with the DA concentration in controls, it had...

journal_title：Neuroscience letters

authors： Tohgi H,Abe T,Takahashi S,Takahashi J,Hamato H

更新日期：1993-09-03 00:00:00

abstract：:Antioxidants may delay or prevent neural diseases. Depletion of the non-enzymatic antioxidant, glutathione, in a mouse model was produced by inhibiting its rate-limiting enzyme, gamma-glutamylcysteine synthetase, for 7 weeks. Ileum and colon were obtained from treated and control (saline) mice. Glutathione levels and ...

journal_title：Neuroscience letters

authors： Koch TR,Fink JG,Ruan E,Petro A,Opara EC

更新日期：1997-10-10 00:00:00

abstract：:An investigation was made of the effect of presynaptic inhibition on paired-pulse facilitation (PPF) of group Ia afferent excitatory postsynaptic potentials (EPSPs). The main finding from this study was that PPF was enhanced during presynaptic inhibition of compound Ia EPSPs. This increase in PPF is identical to that ...

journal_title：Neuroscience letters

authors： Stuart GJ,Redman SJ

更新日期：1991-05-27 00:00:00

abstract：:We have examined the morphology and distribution of nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-diaphorase) cells in the retina of the guinea pig. Two morphologically distinct classes of labelled cells were detected, one with larger, darkly labelled somata commonly located in the inner nuclear layer ...

journal_title：Neuroscience letters

authors： Cobcroft M,Vaccaro T,Mitrofanis J

更新日期：1989-08-14 00:00:00

abstract：:Neuronal density, neuron size, and the number of neurons under 1 mm2 of cerebral cortical surface area were measured in the right pre-frontal cortex of Albert Einstein and five elderly control subjects. Measurement of neuronal density used the optical dissector technique on celloidin-embedded cresyl violet-stained sec...

journal_title：Neuroscience letters

authors： Anderson B,Harvey T

更新日期：1996-06-07 00:00:00

abstract：:We investigated microvascular damage in areas with magnetic resonance imaging (MRI)-defined apparent diffusion coefficient reduction (ADC-R) in a rat model of thromboembolic occlusion of the middle cerebral artery. Rats received either intracarotid recombinant tissue plasminogen activator (rt-PA) or saline. Microvascu...

journal_title：Neuroscience letters

authors： Vosko MR,Busch E,Burggraf D,Bültemeier G,Hamann GF

更新日期：2003-12-26 00:00:00

abstract：:In vitro quantitative autoradiography was used to visualize nicotinic receptors in large cryosections of human brain hemispheres. Sections 80 microns thick of human brain hemispheres were incubated with (-)-[3H]nicotine and the distribution of nicotinic receptors in human brain was studied. Increasing numbers of nicot...

journal_title：Neuroscience letters

authors： Adem A,Nordberg A,Jossan SS,Sara V,Gillberg PG

更新日期：1989-07-03 00:00:00

abstract：:Using immunohistochemistry with specific antisera against dopamine-beta-hydroxylase and phenylethanolamine N-methyltransferase, we present the first description of the adrenergic structures of the sheep medulla oblongata. Dopamine-beta-hydroxylase-immunoreactive perikarya in the sheep brain are localized as described ...

journal_title：Neuroscience letters

authors： Tillet Y

更新日期：1988-12-19 00:00:00

abstract：:The mechanisms responsible for the termination of paroxysmal depolarization shifts (PDS) were studied with intracellular recordings on CA1 neurons of rat hippocampal slices. Epileptiform activity was induced by application of penicillin, bicuculline or Mg-free artificial cerebrospinal fluid (ACSF). PDS in penicillin-c...

journal_title：Neuroscience letters

authors： Domann R,Westerhoff CH,Witte OW

更新日期：1994-07-18 00:00:00

abstract：:Basic fibroblast growth factor (bFGF) has strong neurotrophic effects both in vivo and in vitro on various brain neurons. bFGF enhanced the branching of laser beam-damaged axons of primary cultured hippocampal neurons with a suppression of the neurite's re-elongation. Conditioned medium prepared from astrocytes, on th...

journal_title：Neuroscience letters

authors： Miyagawa T,Saito H,Nishiyama N

更新日期：1993-04-16 00:00:00