Coexistence of galanin and substance P in the mouse nasal mucosa, including the vomeronasal organ.

abstract：OBJECT:Much evidence has demonstrated that stress and tumor interact, but the mechanisms are poorly understood. The purpose of this study is to discuss the effect of unpredictable chronic mild stress (CMS) upon the behavior of Walker 256 tumor-bearing rats and its mechanism. METHODS:Observe the effects of CMS on the s...

journal_title：Neuroscience letters

authors： Xiu LJ,Lin HM,Wei PK

更新日期：2010-03-31 00:00:00

abstract：:We have investigated the effect of ethanol upon vasopressin (AVP) content in brain and upon in-vitro release of AVP from the rat median eminence. In-vitro ethanol concentrations (5-25 mM), comparable to behaviorally relevant blood ethanol levels, induce a substantial inhibition of AVP release from the median eminence,...

journal_title：Neuroscience letters

authors： Brinton RE,Gruener R,Deshmukh P,Yamamura HI

更新日期：1986-06-18 00:00:00

abstract：:Recent studies have suggested the involvement of some metabolic hormones in memory formation and synaptic plasticity. Insulin dysfunction is known as an essential process in the pathogenesis of sporadic Alzheimer's disease (AD). In this study we examined whether adiponectin (ADN), as an insulin-sensitizing adipokine, ...

journal_title：Neuroscience letters

authors： Pousti F,Ahmadi R,Mirahmadi F,Hosseinmardi N,Rohampour K

更新日期：2018-01-01 00:00:00

abstract：:Parkinson's disease (PD) is a common neurodegenerative disease characterized pathologically by the selective loss of dopaminergic neurons in the substantia nigra and the intracellular accumulation of α-synuclein in the Lewy bodies. While the pathogenic mechanisms of PD are poorly understood, many lines of evidence poi...

journal_title：Neuroscience letters

authors： Sheehan P,Yue Z

更新日期：2019-04-01 00:00:00

abstract：:Electrical stimulation delivered to the rostral pons induced well coordinated activity of the intralaryngeal muscles and the ventilatory muscles for vocalization in unanesthetized, decerebrate cats. The stimulation reset the normal respiratory rhythm and induced vocalization with a newly developed rhythm. Continuous o...

journal_title：Neuroscience letters

authors： Sakamoto T,Yamanaka Y,Wada K,Nakajima Y

更新日期：1993-08-06 00:00:00

abstract：:Pineal gland N-acetyltransferase (NAT) activity and pineal and serum levels of melatonin declined linearly in albino rats exposed to different irradiances (low, 170 microW/cm2; moderate, 420 microW/cm2; high, 1040 microW/cm2) red light during the middle of the night. High intensity red light (1040 microW/cm2) was as e...

journal_title：Neuroscience letters

authors： Sun JH,Yaga K,Reiter RJ,Garza M,Manchester LC,Tan DX,Poeggeler B

更新日期：1993-01-04 00:00:00

abstract：:Isolated Helix neurons were internally perfused under voltage-clamp, with drugs applied by the 'concentration clamp' which allowed an extremely rapid switching of the external solution. 4-Aminopyridine (4-AP) at more than 3 X 10(-4) M induced a chloride current (ICl) which could be blocked by D-tubocurarine. Acetylcho...

journal_title：Neuroscience letters

authors： Ikemoto Y,Akaike N,Ono K

更新日期：1987-04-23 00:00:00

abstract：:The antigenic components of Lewy bodies in the cerebral cortex and substantia nigra in 5 cases of diffuse Lewy body disease were examined by immunocytochemistry, using antibodies to neurofilaments (in the phosphorylated or non-phosphorylated forms); to ubiquitin; to the microtubule-associated proteins MAP1, MAP2 and t...

journal_title：Neuroscience letters

authors： Galloway PG,Bergeron C,Perry G

更新日期：1989-05-22 00:00:00

abstract：:Activin A levels are elevated in the cerebrospinal fluid (CSF) of patients with meningitis and in the sera of patients with sepsis. The source(s) of the elevated concentrations of activin A in CSF and serum have not yet been discovered. Here we demonstrate that primary mouse microglial cells and peritoneal macrophages...

journal_title：Neuroscience letters

authors： Ebert S,Zeretzke M,Nau R,Michel U

更新日期：2007-02-21 00:00:00

abstract：:The objective of this study was to determine if yohimbine, a central norepinephrine enhancing drug, increases cortico-motoneuronal excitability in intact humans. Transcranial magnetic stimulation was used to assess excitability of the motor system reflected in the parameters motor threshold, recruitment curve, intraco...

journal_title：Neuroscience letters

authors： Plewnia C,Bartels M,Cohen L,Gerloff C

更新日期：2001-07-06 00:00:00

abstract：:Alzheimer's disease (AD) is characterized by the deposition of amyloid beta-peptide (Abeta), derived from amyloid precursor protein (APP). Membrane states, such as lipid components or membrane fluidity, are important for enzymes related to APP processing in meeting their substrates efficiently. We analyzed the effects...

journal_title：Neuroscience letters

authors： Tanabe C,Ebina M,Asai M,Futai E,Sasagawa N,Katano K,Fukami H,Ishiura S

更新日期：2009-02-06 00:00:00

abstract：:Five min bilateral carotid artery occlusion (BCO) in gerbils results in selective degeneration of neurons in the hippocampus, striatum and cortex, and an increase in spontaneous locomotor activity. These phenomena were examined to determine if an association could be made between the site or degree of neuronal degener...

journal_title：Neuroscience letters

authors： Mileson BE,Schwartz RD

更新日期：1991-07-08 00:00:00

abstract：:Several studies have suggested an important role for brain-derived neurotrophic factor (BDNF) in the pathophysiology and therapeutics of bipolar disorder (BPD). The mechanisms underlying the therapeutic effects of lithium in BPD seem to involve a direct regulation of neurotrophic cascades. However, no clinical study e...

journal_title：Neuroscience letters

authors： de Sousa RT,van de Bilt MT,Diniz BS,Ladeira RB,Portela LV,Souza DO,Forlenza OV,Gattaz WF,Machado-Vieira R

更新日期：2011-04-20 00:00:00

abstract：:The myelin oligodendrocyte glycoprotein (MOG) is a minor CNS myelin-specific protein that is an important candidate autoantigen in multiple sclerosis. We now report that MOG mRNA transcripts are present in the peripheral nervous system of rodents and primates at levels approximately ten-fold lower than in brain as dem...

journal_title：Neuroscience letters

authors： Pagany M,Jagodic M,Schubart A,Pham-Dinh D,Bachelin C,Baron van Evercooren A,Lachapelle F,Olsson T,Linington C

更新日期：2003-10-30 00:00:00

abstract：:Histone modifications, such as lysine methylation, acetylation and ubiquitination, are epigenetic tags that shape the chromatin landscape and regulate transcription required for synaptic plasticity and memory. Here, we show that transcription-promoting histone H3 trimethylated at lysine 4 (H3K4me3), histone H3 acetyla...

journal_title：Neuroscience letters

authors： Bach SV,Tacon PR,Morgan JW,Hegde AN

更新日期：2015-03-30 00:00:00

abstract：:Chronic demyelination and the concomitant loss of trophic support and increased energy demands in axons are thought to contribute to neurodegeneration in a number of neurological diseases such as multiple sclerosis (MS). Adult oligodendrocyte precursor cells (OPCs) play an important role in these demyelinating disease...

journal_title：Neuroscience letters

authors： Harrington EP,Bergles DE,Calabresi PA

更新日期：2020-01-10 00:00:00

abstract：:In rats, immunoreactivity was demonstrated in the brush border of the choroid plexus, in the wall of blood vessels in the brain, and in the brush border of the proximal tubules of the kidney, using the peroxidase-antiperoxidase technique (PAP) and an anti-pulmonary converting-enzyme antibody. These findings correlate ...

journal_title：Neuroscience letters

authors： Rix E,Ganten D,Schüll B,Unger T,Taugner R

更新日期：1981-03-10 00:00:00

abstract：:Gastrin-releasing peptide (GRP) was demonstrated by immunohistochemistry and high-performance liquid chromatography to be present in the great majority of neurons in the geniculate ganglion of rat and man. This was in contrast to findings in the sphenopalatine ganglion of rat, where only little GRP was found, and in t...

journal_title：Neuroscience letters

authors： Hardebo JE,Suzuki N,Ekman R

更新日期：1992-05-25 00:00:00

abstract：:Amyloid beta-peptide (Abeta) deposition in brain is important in the development of Alzheimer's disease (AD). Neprilysin (NEP) appears to be the major Abeta degrading enzyme in vivo and reduced mRNA levels of NEP correlates with increased plaque density. We hypothesized that alterations in the NEP promoter region may ...

journal_title：Neuroscience letters

authors： Lilius L,Forsell C,Axelman K,Winblad B,Graff C,Tjernberg L

更新日期：2003-02-06 00:00:00

abstract：:Infarct volume and immunoreactivities for trkB and trkC in rat brain were compared at 24 h after 90 min of transient middle cerebral artery occlusion (MCAO) between animal groups with or without neurotrophin-3 (NT-3, 10 microg/250 g animal). Treatment of rat brain with topical application of NT-3 significantly reduced...

journal_title：Neuroscience letters

authors： Zhang WR,Hayashi T,Wang JM,Sasaki C,Sakai K,Warita H,Shiro Y,Suenaga H,Ohmae H,Tsuji S,Itoh T,Nishimura O,Nagasaki H,Abe K

更新日期：1999-12-10 00:00:00

abstract：:Dependency of taste buds and taste papillae on innervation has been debated for a long time. Previous research showed neurotrophins, brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3), play an important role for the establishment of the lingual gustatory and somatosensory innervation. BDNF null mutant ...

journal_title：Neuroscience letters

authors： Ito A,Nosrat IV,Nosrat CA

更新日期：2010-03-08 00:00:00

abstract：:Diazoxide is a putative mitochondrial, ATP-sensitive potassium channel opener that has been implicated in neuroprotection in cerebral ischemia. Administered as pretreatment, diazoxide can attenuate ischemia-related neuronal injury, but little is known about the potential neuroprotective properties of the drug when it ...

journal_title：Neuroscience letters

authors： Farkas E,Timmer NM,Domoki F,Mihály A,Luiten PG,Bari F

更新日期：2005-10-28 00:00:00

abstract：:Repeated exposure to dizocilpine (MK-801) can be used as a model of schizophrenia that incorporates disease progression. Proton magnetic resonance spectroscopy (1H MRS) has been widely used to investigate schizophrenia-related alterations in glutamate (Glu). The purpose of this study was to investigate metabolic alter...

journal_title：Neuroscience letters

authors： Yoo CH,Song KH,Lim SI,Lee DW,Woo DC,Choe BY

更新日期：2017-01-10 00:00:00

abstract：:We examined by immunohistochemistry the effect of salt loading on the expression of tyrosine hydroxylase (TH), aromatic L-amino acid decarboxylase (AADC), and GTP cyclohydrolase I (GCH) in Purkinje cells of the mouse cerebellum. In control mice, only a few Purkinje cells were positive for TH or AADC. No Purkinje cells...

journal_title：Neuroscience letters

authors： Sakai M,Fujii T,Karasawa N,Arai R,Nagatsu I

更新日期：1995-07-14 00:00:00

abstract：:The Rose Bengal model in rats is widely used to study brain plasticity, functional recovery and restorative therapies. The present study evaluated temporal profiles of hemorrhage and edema by magnetic resonance imaging (MRI) in rats in relation to sensorimotor impairment after photochemically induced cortical infarct....

journal_title：Neuroscience letters

authors： Jolkkonen J,Jokivarsi K,Laitinen T,Gröhn O

更新日期：2007-11-27 00:00:00

abstract：:Substance P caused a depolarization of cultured spinal neurones which was often accompanied by a decrease in membrane conductance. The peptide usually had no effect on the membrane potential and resistance of glial cells. In contrast to the depolarization by glutamate, which is associated with an influx of Na+ and an ...

journal_title：Neuroscience letters

authors： Hösli L,Hösli E,Zehntner C,Landolt H

更新日期：1981-07-02 00:00:00

abstract：:A series of experiments were designed to examine the potential induction of apoptosis by nitric oxide (NO) donors on cortical neuronal cell culture. A 24 h exposure of three different NO donors, 3-morpholinosydnonimine, S-nitroso-N-acetyl-penicillamine, and S-nitrosoglutathione, induced apoptosis as indicated by follo...

journal_title：Neuroscience letters

authors： Palluy O,Rigaud M

更新日期：1996-04-12 00:00:00

abstract：:Peroxidase-antiperoxidase (PAP) immunocytochemistry at the electron microscopic level was used to describe the fine structural characteristics of vascular connections between vasopressin (VP)-immunoreactive neuronal elements and cerebral microvessels in the rat. In the majority of connections, somata or neural process...

journal_title：Neuroscience letters

authors： Jójárt I,Joó F,Siklós L,László FA

更新日期：1984-10-12 00:00:00

abstract：:For several neurodegenerative disorders, including Parkinson's Disease (PD) and Alzheimer's Disease (AD), microRNAs (miRNAs) have been known to play a crucial role. So, in this study miR-132 and its role in PD cell models was investigated. We wanted to investigate the survival or death pathway involved in PD. We obser...

journal_title：Neuroscience letters

authors： Qazi TJ,Lu J,Duru L,Zhao J,Qing H

更新日期：2021-01-01 00:00:00

abstract：:Previous in vivo studies have indicated that both arginine vasopressin (AVP) and angiotensin II (ANG II) can modulate the baroreflex by acting on the area postrema (AP). In the present study, effects of AVP and ANG II on AP neuronal activity were investigated by recording extracellular activity in a rabbit brainstem s...

journal_title：Neuroscience letters

authors： Cai Y,Bishop VS

更新日期：1995-05-05 00:00:00