Immune cell modulation of oligodendrocyte lineage cells.

abstract：:Magnetic resonance imaging was used to investigate the relation between the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism and volumetric measurements for the medial temporal lobe structures (amygdala, hippocampus, and parahippocampal gyrus) and prefrontal sub-regions (the superior frontal gyrus, middl...

journal_title：Neuroscience letters

authors： Takahashi T,Suzuki M,Tsunoda M,Kawamura Y,Takahashi N,Tsuneki H,Kawasaki Y,Zhou SY,Kobayashi S,Sasaoka T,Seto H,Kurachi M,Ozaki N

更新日期：2008-04-11 00:00:00

abstract：:Rapid removal of synaptically released glutamate from the extracellular space ensures a high signal-to-noise ratio in excitatory neurotransmission. In the cerebellum, glial glutamate transporters, GLAST and GLT-1, are co-localized in the processes of Bergmann glia wrapping excitatory synapses on Purkinje cells (PCs). ...

journal_title：Neuroscience letters

authors： Takatsuru Y,Iino M,Tanaka K,Ozawa S

更新日期：2007-06-08 00:00:00

abstract：:'Clipsin' and other peptide bond hydrolase activities that appear to be integral membrane proteins, including two implicated in the formation of the histological hallmarks of Alzheimer's disease, were assayed in the frontal and parietal cortex from a large (n = 45) series of postmortem human brains. Tissues were extra...

journal_title：Neuroscience letters

authors： Stratmann GC,Webster MT,Francis PT,Procter AW,Bowen DM

更新日期：1992-08-31 00:00:00

abstract：:The cerebellar Purkinje cell is a major site for neurosteroid formation. We have demonstrated recently that the Purkinje cell actively produces sex steroids, such as estradiol and progesterone, de novo from cholesterol only during rat neonatal life, when cerebellar cortical formation occurs. We have further demonstrat...

journal_title：Neuroscience letters

authors： Shikimi H,Sakamoto H,Mezaki Y,Ukena K,Tsutsui K

更新日期：2004-07-01 00:00:00

abstract：:Recent reports have suggested that variants in the sortilin-related receptor gene (SORL1) increase the risk of late onset Alzheimer's disease (AD) in Northern European, Hispanic, African-American and Isreali-Arab populations. SORL1 directs trafficking of amyloid precursor protein (APP) and under-expression of SORL1 ma...

journal_title：Neuroscience letters

authors： Lee JH,Chulikavit M,Pang D,Zigman WB,Silverman W,Schupf N

更新日期：2007-09-25 00:00:00

abstract：:We observed ontogenetic changes of neuropeptide Y (NPY)-like-immunoreactivity in the terminal nerve (TN) of the chum salmon, a teleost, and the cloudy dogfish, an elasmobranch. In the chum salmon, NPY-like-immunoreactive (NPY-IR) cells first appeared in the olfactory placode of embryos at 16 days after fertilization, ...

journal_title：Neuroscience letters

authors： Chiba A,Oka S,Honma Y

更新日期：1996-07-26 00:00:00

abstract：:To establish a model for functional hyperemia in the rat visual cortex, cortical blood flow responses to flash stimulation were measured with the laser Doppler flow (LDF) technique at various levels of halothane anesthesia. The concentration-dependent effect of halothane on arterial pressure and its consequent effect ...

journal_title：Neuroscience letters

authors： Schulte ML,Hudetz AG

更新日期：2006-02-06 00:00:00

abstract：:Nerve ligation injury in rats may represent a useful model of some clinical neuropathic pains. Activation of N-methyl-D-aspartate (NMDA) receptors may maintain central sensitivity and contribute to neuropathic pain. Here, nerve injury was produced by unilateral ligation of the L5 and L6 spinal roots of the sciatic ner...

journal_title：Neuroscience letters

authors： Ossipov MH,Lopez Y,Nichols ML,Bian D,Porreca F

更新日期：1995-10-20 00:00:00

abstract：:The cellular localization of Thy-1 in the chick retina was investigated by selectively destroying certain populations of neurons with toxins. In control retinae four weeks after intravitreal injection of vehicle, there was strong immunoreactivity for Thy-1 in the nerve fibre layer, ganglion cell layer and inner plexif...

journal_title：Neuroscience letters

authors： Sheppard AM,Konopka M,Robinson SR,Morgan IG,Jeffrey PL

更新日期：1991-02-11 00:00:00

abstract：:IL-1beta is a proinflammatory cytokine that contributes to psychological stress responses and has been implicated in various psychiatric disorders most notably depression. Preclinical studies also demonstrate that IL-1beta modulates anxiety- and fear-related behaviors, although these findings are difficult to assess b...

journal_title：Neuroscience letters

authors： Koo JW,Duman RS

更新日期：2009-05-29 00:00:00

abstract：:Synaptotagmin I (Syt I), a possible Ca(2+) sensor for neurotransmitter release, was suggested to be involved in neurite outgrowth of chick dorsal root ganglion (DRG) neurons, based on introduction of the antibody against the C2A domain into cells via mechanical lesions. Recently, however, the functional block antibody...

journal_title：Neuroscience letters

authors： Fukuda M,Mikoshiba K

更新日期：2000-12-01 00:00:00

abstract：:Polypeptides phosphorylated in vivo in Drosophila mutants defective in learning and memory, were characterized by polyacrylamide gel electrophoresis of subcellular fractions obtained by phase partitioning in Triton X-114 [3]. In the mutants turnip, dunce and Shaker, one or more bands at a molecular weight range of 50-...

journal_title：Neuroscience letters

authors： Buxbaum JD,Dudai Y

更新日期：1989-10-09 00:00:00

abstract：:We used whole-head magnetoencephalography to investigate cortical activity during two oromotor activities foundational to speech production. 13 adults performed mouth opening and phoneme (/pa/) production tasks to a visual cue. Jaw movements were tracked with an ultrasound-emitting device. Trials were time-locked to b...

journal_title：Neuroscience letters

authors： Memarian N,Ferrari P,Macdonald MJ,Cheyne D,De Nil LF,Pang EW

更新日期：2012-10-03 00:00:00

abstract：:Hearing impairment affects 1 in 500 newborns worldwide and nearly one out of three people over the age of 65 (WHO, 2019). Hereditary hearing loss is the most common type of congenital deafness; genetic factors also affect deafness susceptibility. Gene therapies may preserve or restore natural sound perception, and hav...

journal_title：Neuroscience letters

authors： Kang W,Sun Z,Zhao X,Wang X,Tao Y,Wu H

更新日期：2019-09-14 00:00:00

abstract：BACKGROUND:Studies have demonstrated that the failure of oligodendrocyte precursor cells (OPCs) differentiation as a major cause of remyelination failure in demyelinating disease. The reasons for this failure are not completely understood. We hypothesized that the present of myelin debris in CNS play an important role ...

journal_title：Neuroscience letters

authors： Liu Q,Lv HW,Yang S,He YQ,Ma QR,Liu J

更新日期：2020-04-23 00:00:00

abstract：:Both the onset of and recovery from desensitization of three types of responses to acetylcholine in Aplysia californica occurred by biphasic kinetics. The fast component of onset recovered at a slower rate than the slow component of onset. The rates of onset and recovery were widely different when the three response t...

journal_title：Neuroscience letters

authors： Chesnut TJ,Carpenter DO

更新日期：1983-09-09 00:00:00

abstract：:This study aims to investigate the relationship between DNA methylation and expression of human dopamine transporter (hDAT). We examined methylation status of hDAT in cells with various hDAT expression levels, including two dopaminergic neural cell lines (SK-N-AS and SH-SY-5Y) and one non-dopaminergic cell line (HEK29...

journal_title：Neuroscience letters

authors： Zhai D,Li S,Dong G,Zhou D,Yang Y,Wang X,Zhao Y,Yang Y,Lin Z

更新日期：2018-01-01 00:00:00

abstract：:We report a sporadic case of tauopathy with unusual clinical and neuropathological features. The patient presented with progressive symmetric rigid-akinetic parkinsonism and dementia of the subcortical type. Magnetic resonance imaging of the brain revealed atrophy resembling multiple system atrophy. The level of cereb...

journal_title：Neuroscience letters

authors： Ohara S,Tsuyuzaki J,Oide T,Arai H,Higuchi S,Hasegawa M,Iwatsubo T

更新日期：2002-09-13 00:00:00

abstract：:Peripheral neuropathic pain is a common complication in the diabetic patients, and the underlying central mechanism remains unclear. Forebrain anterior cingulate cortex (ACC) is critically involved in the supraspinal perception of physical and affective components of noxious stimulus and pain modulation. Excitatory gl...

journal_title：Neuroscience letters

authors： Li W,Wang P,Li H

更新日期：2014-05-07 00:00:00

abstract：:Dopamine (DA) neurons in the ventral tegmental area and substantia nigra pars compacta were induced to fire in bursts with application of N-methyl-D-aspartate (NMDA, 20 microM) and apamin (100 nM) while recording intracellularly in the rat brain slice. L-Arginine (300 microM), a substrate for nitric oxide (NO) product...

journal_title：Neuroscience letters

authors： Cox BA,Johnson SW

更新日期：1998-10-23 00:00:00

abstract：:The release of endogenous calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) from slices of dorsal and ventral thoraco-lumbar spinal cord was examined using a fixed volume incubation technique and radioimmunoassay. Incubation with potassium (25-100 mM) produced a dose-related increase in basal CGRP-LI in ...

journal_title：Neuroscience letters

authors： Scott MA,Fone KC

更新日期：1994-07-04 00:00:00

abstract：:Tryptophan hydroxylase 2 (TPH2) is a rate-limiting enzyme of neuronal serotonin biosynthesis. Recently, two single nucleotide polymorphisms (SNPs) at the exon 11 coding region that resulted in amino acid substitutions in the C-terminal domain have been reported to affect enzyme activity in humans and mice. We determin...

journal_title：Neuroscience letters

authors： Hong KW,Sugawara Y,Hasegawa H,Hayasaka I,Hashimoto R,Ito S,Inoue-Murayama M

更新日期：2007-02-02 00:00:00

abstract：:Effects of substance P and extracellular [K(+)](o) on respiratory motor activity in the ventrolateral medulla in neonatal rat (0-4 days old) brainstem-spinal cord preparation were studied. In addition to fictive eupneic rhythm (8-13 bursts/minute), the respiratory motor output was composed of biphasic bursts which mig...

journal_title：Neuroscience letters

authors： Shvarev YN,Lagercrantz H,Yamamoto Y

更新日期：2003-08-14 00:00:00

abstract：:Previous studies indicate that the locus coeruleus (LC) can be divided into sub-areas depending upon dominant efferent projection zones. Ascending projections to the forebrain originate within the dorsal half and projections to the spinal cord and the cerebellum course from the ventral half of the LC. Using Sprague-Da...

journal_title：Neuroscience letters

authors： Babstock D,Malsbury CW,Harley CW

更新日期：1997-03-21 00:00:00

abstract：:Parkinson's disease (PD) is one of the common neurodegenerative diseases that result in the progressive damage of dopaminergic neurons. Environmental exposure, including paraquat, is considered risky for PD. Epigenetics refer to the study of heritable changes in gene expression that occur without a change in DNA seque...

journal_title：Neuroscience letters

authors： Kong M,Ba M,Liang H,Ma L,Yu Q,Yu T,Wang Y

更新日期：2012-08-22 00:00:00

abstract：:The somatosensory system is capable of functional reorganization following peripheral denervation or training. Studies on human amputees with phantom limb pain provided evidence that these reorganizational changes are modulated through nociceptive input. In the present study we used magnetoencephalographic recordings ...

journal_title：Neuroscience letters

authors： Sörös P,Knecht S,Bantel C,Imai T,Wüsten R,Pantev C,Lütkenhöner B,Bürkle H,Henningsen H

更新日期：2001-02-09 00:00:00

abstract：:Nucleus rostrolateralis is a distinctive diencephalic nucleus in some ray-finned fishes. In the osteoglossomorph Pantodon, it is a large ovoid nucleus with visual system connections. A topologically and cytoarchitectonically similar nucleus has been found in six species of non-osteoglossomorph fishes, two species of g...

journal_title：Neuroscience letters

authors： Saidel WM,Butler AB

更新日期：1997-06-20 00:00:00

abstract：:Involvement of 5-hydroxytryptaminergic (5-HT) system for aglycemia- and ischemia-induced depression of the spinal reflexes was evaluated. The monosynaptic (MSR) and polysynaptic (PSR) reflex potentials were elicited in the ventral root by stimulating the corresponding dorsal root in an isolated spinal cord from neonat...

journal_title：Neuroscience letters

authors： Deshpande SB,Jha A

更新日期：2004-11-30 00:00:00

abstract：:In previous studies, chronic low-dose methylphenidate (MPH) administration during early development has been shown to increase emotional responding in adulthood. However, most studies employed male subjects, which generally show enhanced fear relative to females in laboratory tests of anxious behaviors. The present st...

journal_title：Neuroscience letters

authors： Bethancourt JA,Vásquez CE,Britton GB

更新日期：2011-05-27 00:00:00

abstract：:Acute and chronic damage to the central nervous system (CNS) releases large quantities of ATP. Whereas the ATP concentration in the extracellular space is normally in the micromolar range, under these conditions it increases to millimolar levels. A number of ligand-gated cationic channels termed P2X receptors (7 mamma...

journal_title：Neuroscience letters

authors： Franke H,Illes P

更新日期：2014-04-17 00:00:00