Transient patterns of calbindin-D28k expression in the developing striatum of man.

Abstract:

:In fetal and adult human brains, calbindin immunoreactivity (CB-ir) of neostriatal neuropil showed inhomogeneous pattern. A mosaic of CB-ir neuropil patches matching the acetylcholinesterase (AChE)-reactive patches and most of the encapsulated cell-dense islands was distributed in a lighter stained background matrix. During infancy, the pattern of CB expression changed from one of CB-rich patches to one of CB-poor striosomes and rich matrix. Furthermore, we observed a steady development of population of medium-sized neurons in the striatal matrix; in addition, a transient CB-expression was found in cells of the ganglionic eminence and presumably in a subset of striatal interneurons.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Letinić K,Kostović I

doi

10.1016/s0304-3940(96)13270-5

subject

Has Abstract

pub_date

1996-12-20 00:00:00

pages

211-4

issue

3

eissn

0304-3940

issn

1872-7972

pii

S0304394096132705

journal_volume

220

pub_type

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