Involvement of extracellular matrix in acetylcholine receptor epsilon-subunit gene expression at the rat neuromuscular junction.

abstract：:Incorporation of the N-methyl-d-aspartate receptor (NMDAR) subunit NR3A into functional NMDARs results in reduced channel conductance and Ca(2+) permeability. To further investigate the function of NR3A, we have set out to characterize its intracellular binding partners. Here, we report a novel protein interaction bet...

journal_title：Neuroscience letters

authors： Eriksson M,Samuelsson H,Björklund S,Tortosa E,Avila J,Samuelsson EB,Benedikz E,Sundström E

更新日期：2010-05-07 00:00:00

abstract：:The lysate of an immortalized monoclonal cell line derived from the striatum (X61) contains a dopaminergic stimulatory activity that is capable of increasing the dopamine content of an immortalized mouse mesencephalic cell line (MN9D) which expresses a dopaminergic phenotype. Purification of an isoamyl alcohol extract...

journal_title：Neuroscience letters

authors： Heller A,Won L,Bubula N,Hessefort S,Kurutz JW,Reddy GA,Gross M

更新日期：2005-03-07 00:00:00

abstract：:The microiontophoretic application of morphine to single globus pallidus neurons in morphine naive rats resulted in a depression of both spontaneous and glutamate-evoked firing of these neurons. Seventy percent of all pallidal neurons on which morphine was tested exhibited some degree of depression of neuronal dischar...

journal_title：Neuroscience letters

authors： Huffman RD,Felpel LP

更新日期：1981-03-10 00:00:00

abstract：:Systemic administration of nitroglycerin (NTG) consistently provokes spontaneous-like migraine attacks in migraine sufferers, and in rat it induces hyperalgesia and allodynia. In the present study we modeled migraine headache by intraperitoneal (i.p.) injection of a single dose of NTG, which produced widespread therma...

journal_title：Neuroscience letters

authors： Farajdokht F,Babri S,Karimi P,Mohaddes G

更新日期：2016-09-06 00:00:00

abstract：:A characteristic of Parkinson's disease (PD) is the development of tremor within the 4-6Hz range. One method used to better understand pathological tremor is to compare the responses to tremor-type actions generated intentionally in healthy adults. This study was designed to investigate the similarities and difference...

journal_title：Neuroscience letters

authors： Morrison S,Cortes N,Newell KM,Silburn PA,Kerr G

更新日期：2013-02-08 00:00:00

abstract：:Intracellular recording techniques were used to monitor the evoked responses in hippocampal CA1 pyramidal cells following focal stimulation of the proximally and distally located apical dendritic synapses. The local anaesthetic, QX-314, when injected into individual cells, caused a complete time-dependent blockade of ...

journal_title：Neuroscience letters

authors： Colling SB,Wheal HV

更新日期：1994-05-19 00:00:00

abstract：:We have recently observed that the free radical-generating mixture of xanthine and xanthine oxidase (X/XO) can suppress the inhibitory effects of adenosine on synaptic transmission in the hippocampus, but that this action can be mimicked by xanthine alone. We have now clarified the mechanism of these interactions by u...

journal_title：Neuroscience letters

authors： Shahraki A,Fukunari A,Stone TW

更新日期：2004-07-29 00:00:00

abstract：:Astrocytes are effectively involved in the pathophysiological processes in the central nervous system (CNS) and may contribute to or protect against development of inflammatory and degenerative diseases. Sildenafil is a potent and selective phosphodiesterase-5 (PDE-5) inhibitor, which induces cyclic GMP accumulation. ...

journal_title：Neuroscience letters

authors： de Santana Nunes AK,Rapôso C,Björklund U,da Cruz-Höfling MA,Peixoto CA,Hansson E

更新日期：2016-09-06 00:00:00

abstract：:Vertical arm pointing movements in two directions (upwards and downwards), imposing two different loads (unload and 0.5 kg) and speeds (normal and fast) have been studied in six subjects. Movements were recorded using an optoelectronic system. Data analysis concentrated upon finger-tip kinematics. Significant effects ...

journal_title：Neuroscience letters

authors： Papaxanthis C,Pozzo T,Stapley P

更新日期：1998-09-04 00:00:00

abstract：:The distributions of central amygdaloid nucleus (Ce) neurons projecting to different medullary regions were investigated using the retrograde transport of iontophoretically applied Fast Blue or bisbenzimide. Neurons projecting to the nucleus of the solitary tract were located throughout the medial, lateral and ventral...

journal_title：Neuroscience letters

authors： Thompson RL,Cassell MD

更新日期：1989-02-27 00:00:00

abstract：:Compared to other M(1) muscarinic acetylcholine receptor (M(1) mAChR) agonists, xanomeline demonstrates both reversible and persistent modes of binding to the receptor. In our study, we investigated the long-term consequences of brief incubation of Chinese hamster ovary cells expressing M(1) mAChR (M(1)-CHO) with low ...

journal_title：Neuroscience letters

authors： De Lorme KC,Sikorski KL,Grant MK,El-Fakahany EE

更新日期：2006-12-13 00:00:00

abstract：:Tau is a neuronal microtubule-associated protein whose function is regulated by site-specific phosphorylation. One protein kinase that is likely to play an important role in regulating the phosphorylation state of tau in vivo is glycogen synthase kinase (GSK) 3beta. The activity of GSK3beta is regulated by specific pr...

journal_title：Neuroscience letters

authors： Matthews TA,Johnson GV

更新日期：2005-08-26 00:00:00

abstract：:Pituitary adenylate cyclase activating polypeptide (PACAP) and its receptors occur throughout the nervous system, including the retina. PACAP exerts diverse actions in the eye: it influences ocular blood flow, contraction of the ciliary muscle, and has retinoprotective effects. This effect has been proven in different...

journal_title：Neuroscience letters

authors： Kiss P,Atlasz T,Szabadfi K,Horvath G,Griecs M,Farkas J,Matkovits A,Toth G,Lubics A,Tamas A,Gabriel R,Reglodi D

更新日期：2011-01-10 00:00:00

abstract：:Radiofrequency lesions of the ventral mesencephalic tegmentum (VMT), a region located above the nucleus interpeduncularis, provoked a disappearance of the spontaneous alternation behavior. The lesioned rats scores (44%) are not different from the chance level, while the alternation rate amounts to 77% in the control g...

journal_title：Neuroscience letters

authors： Galey D,Jaffard R,Le Moal M

更新日期：1976-09-01 00:00:00

abstract：:We evaluated the effect of cabergoline on superoxide anion production by rat microglial cells using a 2-methyl-6-(p-methoxyphenyl)-3,7-dihydroimidazo[1, 2-a]pyrazin-3-one-dependent chemiluminescence assay. Cabergoline dose-dependently inhibited superoxide anion production by microglial cells stimulated with phorbol my...

journal_title：Neuroscience letters

authors： Yoshida T,Tanaka M,Suzuki Y,Sohmiya M,Okamoto K

更新日期：2002-09-13 00:00:00

abstract：:Human monocytes and a variety of tissue macrophages, including microglia, were studied immunohistochemically to determine the expression of a novel microglial marker, human glucose transporter 5 (hGLUT5), in these cells. The hGLUT5 was not expressed in most peripheral macrophages in the normal state, but weakly expres...

journal_title：Neuroscience letters

authors： Sasaki A,Horikoshi Y,Yokoo H,Nakazato Y,Yamaguchi H

更新日期：2003-02-20 00:00:00

abstract：:Circadian rhythms of pineal melatonin release were measured in freely moving pigeons (Columba livia) by in vivo microdialysis. The birds were placed in light-dark cycles with 12 h of light and 12 h of darkness (LD 12:12) or continuous dim light (LLdim) after LD 12:12. Although the level of melatonin was various, daily...

journal_title：Neuroscience letters

authors： Hasegawa M,Ebihara S

更新日期：1992-12-14 00:00:00

abstract：:IL-1beta is a proinflammatory cytokine that contributes to psychological stress responses and has been implicated in various psychiatric disorders most notably depression. Preclinical studies also demonstrate that IL-1beta modulates anxiety- and fear-related behaviors, although these findings are difficult to assess b...

journal_title：Neuroscience letters

authors： Koo JW,Duman RS

更新日期：2009-05-29 00:00:00

abstract：:A major action of adenosine is the induction of profound behavioral inactivity. 6-(4-Nitrobenzyl)-thioinosine (NBI) and 6-(2-hydroxy-5-nitrobenzyl)-thioguanosine (NBG) have been shown to inhibit adenosine uptake. To investigate the possible synergism between exogenous ligand and reuptake inhibition, mice were treated ...

journal_title：Neuroscience letters

authors： Crawley JN,Patel J,Marangos PJ

更新日期：1983-04-11 00:00:00

abstract：:Schisandra chinensis is commonly used for food and as a traditional remedy for the treatment of neuronal disorders. However, it is unclear which component of S. chinensis is responsible for its neuropharmacological effects. To answer this question, we isolated α-iso-cubebene, a dibenzocyclooctadiene lignin, from S. ch...

journal_title：Neuroscience letters

authors： Park SY,Park SJ,Park NJ,Joo WH,Lee SJ,Choi YW

更新日期：2013-10-25 00:00:00

abstract：:There is a growing interest for using quantitative EEG and LORETA current source density in clinical and research settings. Importantly, if these indices are to be employed in clinical settings then the reliability of these measures is of great concern. Neuroguide (Applied Neurosciences) is sophisticated software deve...

journal_title：Neuroscience letters

authors： Cannon RL,Baldwin DR,Shaw TL,Diloreto DJ,Phillips SM,Scruggs AM,Riehl TC

更新日期：2012-06-14 00:00:00

abstract：:Parkinson's disease (PD) is characterized by bradykinesia, resting tremor, rigidity and postural instability as well as early symptoms. Previous studies that evaluated the association between H1/H2 MAPT haplotype and PD were mostly conducted in European populations in which the H1 haplotype was a reported risk factor ...

journal_title：Neuroscience letters

authors： Miranda-Morales EG,Sandoval-Carrillo A,Castellanos-Juárez FX,Méndez-Hernández EM,La Llave-León O,Quiñones-Canales G,Ruano-Calderón LA,Arias-Carrión O,Salas-Pacheco JM

更新日期：2019-01-18 00:00:00

abstract：:Motor nerve supplies to 15 poles of rat lumbrical spindle were reconstructed from serial, 1-micron transverse sections of muscle embedded in resin. Neural and muscular elements associated with the modulation of static sensitivity of afferents were deficient in these spindles relative to cat tenuissimus and rat soleus ...

journal_title：Neuroscience letters

authors： Walro JM,Kucera J

更新日期：1985-09-06 00:00:00

abstract：:Heme oxygenase (HO-1) gene expression was studied in the brains of rats subjected to 30 min global cerebral ischemia followed by recirculation of up to 24 h. Total RNA was isolated from the cerebral cortex, striatum and hippocampus and reverse-transcribed into cDNA. cDNA was taken as template for PCR using HO-1-specif...

journal_title：Neuroscience letters

authors： Paschen W,Uto A,Djuricic B,Schmitt J

更新日期：1994-10-10 00:00:00

abstract：:The effect of diffuse luminance flicker stimulation of a large area (approximately 30 degrees diameter) on red blood cell flux (F) in the optic nerve head was measured in the anesthetized cat. F increased markedly during sustained flicker. The F-response to the initiation and cessation of the stimulation was found to ...

journal_title：Neuroscience letters

authors： Riva CE,Harino S,Shonat RD,Petrig BL

更新日期：1991-07-22 00:00:00

abstract：:The functional interaction in the spinal cord between substance P and excitatory amino acid agonists was investigated. Behavioural responses were scored in mice after intrathecal administration of excitatory amino acid agonists and substance P, given separately or in combination. A strong potentiation of the effect wa...

journal_title：Neuroscience letters

authors： Mjellem-Joly N,Lund A,Berge OG,Hole K

更新日期：1991-11-25 00:00:00

abstract：:Recently, a series of both non-coding (intronic) and coding (exonic) mutations in the tau gene have been linked to a family of autosomal dominant dementias referred to as frontotemporal dementia-17. While linkage analysis has demonstrated that these mutations segregate with disease in affected families, it is unclear ...

journal_title：Neuroscience letters

authors： Jicha GA,Rockwood JM,Berenfeld B,Hutton M,Davies P

更新日期：1999-02-05 00:00:00

abstract：:Several evidences indicate that PPARgamma stimulation promotes neuronal differentiation. However, to date, no data describe the effects of PPARgamma agonists on neurite outgrowth. Here we have evaluated the effects of pioglitazone, a synthetic PPARgamma agonist, on differentiation and neurite outgrowth in SH-SY5Y huma...

journal_title：Neuroscience letters

authors： Miglio G,Rattazzi L,Rosa AC,Fantozzi R

更新日期：2009-04-24 00:00:00

abstract：:Studies involving receptor protection have been used to define the functional involvement of specific receptor subtypes in tissues expressing multiple receptor subtypes. Previous functional studies from our laboratory demonstrate the feasibility of this approach when applied to neuronal tissues expressing multiple nic...

journal_title：Neuroscience letters

authors： Free RB,Kaser DJ,Boyd RT,McKay DB

更新日期：2006-01-09 00:00:00

abstract：:Previous studies have suggested that motor cortex may be involved in complex control of respiration in man. In this study, we estimated the influence of a simple visuomotor reaction time task (VMT) on the inspiratory airflow curve (IFC) by comparing measurements of standard deviation (SD), C(0) complexity and approxim...

journal_title：Neuroscience letters

authors： Zhang T,Turner D

更新日期：2001-01-05 00:00:00