Abstract:
:Intracellular recording techniques were used to monitor the evoked responses in hippocampal CA1 pyramidal cells following focal stimulation of the proximally and distally located apical dendritic synapses. The local anaesthetic, QX-314, when injected into individual cells, caused a complete time-dependent blockade of the proximal and then the distal action potentials at both threshold and suprathreshold levels of stimulation. This progressive blockade of proximal and distal voltage-dependent sodium channels suggests that sodium action potentials can be generated in the distal apical dendrites of CA1 pyramidal cells.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Colling SB,Wheal HVdoi
10.1016/0304-3940(94)90665-3subject
Has Abstractpub_date
1994-05-19 00:00:00pages
73-96issue
1-2eissn
0304-3940issn
1872-7972pii
0304-3940(94)90665-3journal_volume
172pub_type
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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更新日期:2020-11-01 00:00:00
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:2007-05-17 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:2020-01-10 00:00:00
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:2011-06-01 00:00:00
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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更新日期:2001-06-15 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2007.09.043
更新日期:2007-11-27 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:2020-02-16 00:00:00