Parvalbumin-immunoreactive dystrophic neurites and aberrant sprouts in the cerebral cortex of patients with Alzheimer's disease.

abstract：:Gangliosides are sialic acid-containing sphingolipids that have promoting effects on the survival, growth, and functions of neurons in the central nervous system. Glial cells including astrocytes assist neurons with regard to their proliferation, maintenance, and function. In the present study, we found that astrocyte...

journal_title：Neuroscience letters

authors： Akasako Y,Nara K,Nagai Y,Hashimoto Y

更新日期：2011-01-20 00:00:00

abstract：:Several studies have indicated that higher levels of childhood aerobic fitness is associated with superior cognitive function, and this association is disproportionately observed in tasks requiring greater top-down control. We designed the current study to clarify the relationship between childhood fitness and top-dow...

journal_title：Neuroscience letters

authors： Kamijo K,Takeda Y,Takai Y,Haramura M

更新日期：2016-10-06 00:00:00

abstract：:The neural mechanisms of low back pain (LBP) are still enigmatic. Presently, low back muscles are being discussed as an important source of LBP. Here, the neuroanatomical pathway of the nociceptive information from the caudal multifidus muscle (MF) was studied. True blue was injected into the MF at the level L5 to vis...

journal_title：Neuroscience letters

authors： Taguchi T,John V,Hoheisel U,Mense S

更新日期：2007-10-29 00:00:00

abstract：:In order to clarify the participation of substance P in the expression of opiate withdrawal, we have investigated the effects induced by the new selective neurokinin-1 antagonist RP 67580 on naloxone-induced morphine withdrawal syndrome in rats. Intracerebroventricular administration of RP 67580 elicited a decrease in...

journal_title：Neuroscience letters

authors： Maldonado R,Girdlestone D,Roques BP

更新日期：1993-06-25 00:00:00

abstract：:Brain pericytes are involved in neurovascular dysfunction, neurodegeneration and/or neuroinflammation. In the present study, we focused on the proinflammatory properties of brain pericytes to understand their participation in the induction of inflammation at the neurovascular unit (NVU). The NVU comprises different ce...

journal_title：Neuroscience letters

authors： Matsumoto J,Takata F,Machida T,Takahashi H,Soejima Y,Funakoshi M,Futagami K,Yamauchi A,Dohgu S,Kataoka Y

更新日期：2014-08-22 00:00:00

abstract：:Protein profiling of cerebrospinal fluid in Guillain-Barrè syndrome (GBS), an acute and immune-mediated disease affecting the peripheral nervous system, was performed by two-dimensional electrophoresis. Significant modulated spots in GBS patients vs. control groups (a group of multiple sclerosis patients and one of he...

journal_title：Neuroscience letters

authors： D'Aguanno S,Franciotta D,Lupisella S,Barassi A,Pieragostino D,Lugaresi A,Centonze D,D'Eril GM,Bernardini S,Federici G,Urbani A

更新日期：2010-11-12 00:00:00

abstract：:Neuropeptide Y (NPY)-immunoreactivity has been localized to a rich network of fibres in the uvea of guinea pig and rat. In the iris, NPY-immunoreactive nerves were present in iridial smooth muscle and around blood vessels; similarly throughout the choroid a dense network of NPY-immunoreactive fibres was found surround...

journal_title：Neuroscience letters

authors： Terenghi G,Polak JM,Allen JM,Zhang SQ,Unger WG,Bloom SR

更新日期：1983-11-21 00:00:00

abstract：:The horizontal vestibulo-ocular reflex (VOR) of two groups of rats was measured. One group was bred and kept under hypergravity (HG; 2.5 g) conditions, the other group lived under normal gravity (NG; 1 g). Eye position was recorded in response to horizontal rotatory stimuli. Measurements were made under NG (1 g), and ...

journal_title：Neuroscience letters

authors： Wubbels RJ,de Jong HA

更新日期：2001-04-27 00:00:00

abstract：:Many biochemically diverse proteins can give rise to amyloid fibrils; however, they are all accompanied by P component and glucosaminoglycans. With antibodies specific to apolipoprotein E (apo E) we used immunohistochemical techniques to test for the presence of this protein in both cerebral and systemic amyloid. We f...

journal_title：Neuroscience letters

authors： Wisniewski T,Frangione B

更新日期：1992-02-03 00:00:00

abstract：:The effect of bifemelane hydrochloride (BFH) on the induction of heat shock protein (HSP) 70 and heat shock cognate protein (HSC) 70 mRNAs after transient global ischemia in gerbil brain was investigated by in situ hybridization using cloned cDNA probes selective for each mRNA species. Following 3.5 min of ischemia, H...

journal_title：Neuroscience letters

authors： Aoki M,Abe K,Liu XH,Lee TH,Kato H,Kogure K

更新日期：1993-05-14 00:00:00

abstract：:To evaluate the roles of complement in kainic acid (KA)-induced neuronal damages, the immunohistochemical localization of the complement protein C3 was examined in rat hippocampus after systemic KA injection. The immunoreactivity for C3 was found in glial cells in control rats, and such glial cells were increased in n...

journal_title：Neuroscience letters

authors： Morita H,Suzuki K,Mori N,Yasuhara O

更新日期：2006-11-27 00:00:00

abstract：:English /l/ and /r/ sounds are not distinctive for Japanese speakers and they are loosely associated with corresponding graphemes. The purpose of this study was to investigate the brain activities in the memory process for the graphemes containing 'l' and 'r' in Japanese speakers. Two functional magnetic resonance ima...

journal_title：Neuroscience letters

authors： Sumiyoshi C,Matsuo K,Kato C,Ozawa F,Takehara Y,Isoda H,Isogai S,Sakahara H,Nakai T

更新日期：2003-01-09 00:00:00

abstract：:Approximately 30% of all epilepsy cases are acquired. At present there is no effective strategy to stop epilepsy development after the precipitating insult. Recent data from experimental models pointed to the mTOR pathway, which can be potently inhibited by rapamycin. However, data on the antiepileptic and antiepilept...

journal_title：Neuroscience letters

authors： Sliwa A,Plucinska G,Bednarczyk J,Lukasiuk K

更新日期：2012-02-16 00:00:00

abstract：:The organisation of corticofugal fibres within the basis pedunculi of rats was studied using wheat germ agglutinin-horseradish peroxidase as an orthograde tracer. Following cortical injections, labelled fibres were distributed within the cerebral peduncle in an orderly way. Fibres which originate from cells in the fro...

journal_title：Neuroscience letters

authors： Glickstein M,Kralj-Hans I,Legg C,Mercier B,Ramna-Rayan M,Vaudano E

更新日期：1992-01-20 00:00:00

abstract：:In vivo formation of 1-methyl-4-phenylpyridinium ion (MPP(+)) in the striatum, and dopaminergic neurotoxicity following systemic administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in the presence and absence of calcium channel agonist (+/-)-Bay K8644 were analyzed in Balb/c mice. We used HPLC-photod...

journal_title：Neuroscience letters

authors： Samantaray S,Mohanakumar KP

更新日期：2003-07-31 00:00:00

abstract：:The aim of the study was to investigate the characteristics of the oscillatory dynamics of brain activity during the perception of negative, positive, and neutral sentences in healthy individuals with differing severity of depressive symptoms at the preclinical stage. The study involved 34 healthy people (22 women). T...

journal_title：Neuroscience letters

authors： Bocharov AV,Savostyanov AN,Tamozhnikov SS,Merkulova EA,Saprigyn AE,Proshina EA,Knyazev GG

更新日期：2020-05-29 00:00:00

abstract：:Activation of central neuropeptide Y (NPY) receptors is known to produce several behavioral effects, including feeding, modulation of memory and antagonism of behavioral effects of stress. In addition, experiments in knock-out and transgenic mice have suggested a possible role of NPY regulation of voluntary ethanol in...

journal_title：Neuroscience letters

authors： Thorsell A,Rimondini R,Heilig M

更新日期：2002-10-25 00:00:00

abstract：:Serotonin type-3 (5-HT3) receptors are cation permeable membrane receptors which are involved in modulation of calcium entry in neuronal cells. Along with other ion-channels such as the N-methyl-D-aspartate receptor, it appears to be a target for the actions of ethanol and has been the focus of considerable work in th...

journal_title：Neuroscience letters

authors： Li X,DePetrillo PB

更新日期：2002-10-11 00:00:00

abstract：:Methamphetamine (METH) is one of the most commonly abused substances in today's society. Many studies have shown that the process of cell death induced by METH involves with the reception of death signals, an increase in pro-apoptotic proteins (Bax) and an activation of cysteine protease death pathway. The objective o...

journal_title：Neuroscience letters

authors： Chetsawang J,Suwanjang W,Pirompul N,Govitrapong P,Chetsawang B

更新日期：2012-01-06 00:00:00

abstract：:N-Methyl-D-aspartate (NMDA), quisqualate, kainate and potassium increased, in a dose-dependent manner, the efflux of radioactivity from rat cerebral cortex minislices preincubated with [3H]choline. Ketamine (1-5 microM) and magnesium (0.1-1 mM) reduced only the release evoked by NMDA. The non-parallel shift of the NMD...

journal_title：Neuroscience letters

authors： Lodge D,Johnston GA

更新日期：1985-05-23 00:00:00

abstract：:The present investigation describes for the first time leg lateral abduction performance during long-term microgravity exposure. Two astronauts took part in the experiments, starting 2 weeks into the mission and lasting for 5 months. Results on joint angles kinematics confirm previous investigations on parabolic fligh...

journal_title：Neuroscience letters

authors： Pedrocchi A,Baroni G,Mouchnino L,Ferrigno G,Pedotti A,Massion J

更新日期：2002-02-22 00:00:00

abstract：:In the present study, we describe the distribution of GABAC ρ3 receptor immunoreactivity in the cortex, striatum and hippocampus of wild type (wt) and 11 weeks old HD transgenic (tg) R6/2 mouse brain. In the brain of wt mice, GABAC ρ3 immunoreactivity is well expressed in neuronal cells, nerve fibers and axonal proces...

journal_title：Neuroscience letters

authors： Kumar U,Heer M,Somvanshi RK

更新日期：2017-02-15 00:00:00

abstract：:Recent studies have demonstrated that genetic factors modify susceptibility to sporadic Parkinson's disease (PD). So far the results of candidate gene studies have been conflicting. It has been suggested that polymorphisms in apolipoprotein E (APOE), PARKIN and catechol-O-methyltransferase (COMT) genes might increase ...

journal_title：Neuroscience letters

authors： Eerola J,Launes J,Hellström O,Tienari PJ

更新日期：2002-09-27 00:00:00

abstract：:To determine whether mutations in the coding region of the alpha-synuclein gene are relevant in cases of multiple system atrophy (MSA), detailed nucleotide sequence analysis of the alpha-synuclein gene was performed using total RNA obtained from autopsied brain specimens of 11 pathologically confirmed cases of MSA. Th...

journal_title：Neuroscience letters

authors： Ozawa T,Takano H,Onodera O,Kobayashi H,Ikeuchi T,Koide R,Okuizumi K,Shimohata T,Wakabayashi K,Takahashi H,Tsuji S

更新日期：1999-07-30 00:00:00

abstract：:P2Y(1) is probably an important subtype of purinergic receptors (P2Rs) in modulation of the astrocyte activation in spinal cord. The aim of this study was to observe the effect of P2Y(1) receptor on the abnormal energy metabolism of the cultured rat spinal astrocyte induced by extracellular adenosine diphosphate (ADP)...

journal_title：Neuroscience letters

authors： Cui J,Ou S,He WJ,Du L,Zhao YD,Ruan HZ

更新日期：2011-10-10 00:00:00

abstract：:The individual biological activities of many neurotrophic factors and their variants, which are produced by alternative splicing and proteolytic processing, often remain to be characterized. Bacterial protein production combined with protein refolding and purification is a conventional procedure to obtain active neuro...

journal_title：Neuroscience letters

authors： Wang R,Iwakura Y,Araki K,Sotoyama H,Takei N,Nawa H

更新日期：2011-06-22 00:00:00

abstract：:In mammals, methyl-CpG binding proteins play a significant role in the control of gene expression through their association with chromatin-remodeling complexes. Mutations in the gene coding for methyl-CpG-binding protein 2 (MECP2) cause Rett syndrome and have also been reported in a number of X-linked mental retardati...

journal_title：Neuroscience letters

authors： dos Santos JM,Abdalla CB,Campos M Jr,Santos-Rebouças CB,Pimentel MM

更新日期：2005-04-29 00:00:00

abstract：:The aim of the present study is to show that the sensorimotor system makes a differential use of visual and internal (proprioception and efferent copy) signals when evaluating either the spatial or the dynamical components of our own motor response carried out under a remote visual feedback. Subjects were required to ...

journal_title：Neuroscience letters

authors： Boy F,Palluel-Germain R,Orliaguet JP,Coello Y

更新日期：2005-09-23 00:00:00

abstract：:We recently showed that the RNA regulator, HuR, is translocated to the cytoplasm in astrocytes in the acute phase of spinal cord injury (SCI), consistent with its activation. HuR positively modulates expression of many pro-inflammatory factors, including IL-1β, TNF-α, and MMP-12, which are present at high levels in th...

journal_title：Neuroscience letters

authors： Kwan T,Floyd CL,Patel J,Mohaimany-Aponte A,King PH

更新日期：2017-06-09 00:00:00

abstract：:Electrical stimulation of the A1 noradrenergic region of the ventrolateral medulla produced synatic excitation (n = 19, 9%), inhibition (n = 5, 2%) or no effect (n = 184, 89%) in the activity of a total of 208 neurons in the subfornical organ (SFO) in male rats under urethane anesthesia. Almost all (n = 18) of the exc...

journal_title：Neuroscience letters

authors： Tanaka J,Mashiko N,Kawakami A,Hatakenaka S,Fujisawa S,Nomura M

更新日期：2002-10-25 00:00:00