Alterations of fatty acid composition and metabolism in APP/PS1 transgenic mice.

abstract：:The distribution and origin of axon terminals containing nitric oxide synthase (NOS) were examined in the nucleus of the solitary tract (NST) of the rat by NADPH diaphorase histochemistry combined with nodose ganglionectomy. Axon terminals with NADPH diaphorase activity were densely distributed in the middle and cauda...

journal_title：Neuroscience letters

authors： Lü Y,Ding YQ,Qin BZ,Li JS

更新日期：1994-04-25 00:00:00

abstract：:Curcumin is capable of promoting peripheral nerve regeneration in normal condition. However, it is unclear whether its beneficial effect on nerve regeneration still exists under diabetic mellitus. The present study was designed to investigate such a possibility. Diabetes in rats was developed by a single dose of strep...

journal_title：Neuroscience letters

authors： Ma J,Yu H,Liu J,Chen Y,Wang Q,Xiang L

更新日期：2016-01-01 00:00:00

abstract：:Cortical cells in primary culture contain active proteolytic enzymes capable of cleaving nociceptin/orphanin FQ (N/OFQ) and dynorphins to shorter, bioactive fragments. Cells were divided into subpopulations (neurons, astrocytes and oligodendrocytes), and the metabolic pathways in particular populations of the cells we...

journal_title：Neuroscience letters

authors： Suder P,Bogusiewicz A,Rolka K,Laidler P,Kotlinska J,Silberring J

更新日期：2003-09-18 00:00:00

abstract：:Changes in adenosine 3',5'-cyclic monophosphate (cAMP) concentration were measured in cortical synaptosomes. Preincubation with adenosine deaminase reduced cAMP concentration by 45%. Oxotremorine, clonidine, gamma-aminobutyric acid (GABA) and baclofen produced no change in basal concentration. 2-Chloroadenosine and no...

journal_title：Neuroscience letters

authors： Fillenz M,Bloomfield MR

更新日期：1986-02-28 00:00:00

abstract：:The role of hippocampal noradrenergic inputs in the modulation of corticosteroid receptor expression has been investigated. Adult male rats were given central 6-hydroxydopamine (6-OHDA) and the expression of hippocampal mineralocorticoid (MR) and glucocorticoid (GR) receptor mRNA was examined after two weeks by in sit...

journal_title：Neuroscience letters

authors： Yau JL,Seckl JR

更新日期：1992-08-17 00:00:00

abstract：:Although Streptococcus pneumoniae is the major cause of meningitis, how it causes disease is poorly understood. The C-type lectin SIGN-R1 mediates the recently described SIGN-R1 complement activation pathway, which operates against capsular polysaccharides (CPSs) of S. pneumoniae in splenic marginal macrophages. Here,...

journal_title：Neuroscience letters

authors： Park JY,Choi HJ,Prabagar MG,Choi WS,Kim SJ,Cheong C,Park CG,Chin CY,Kang YS

更新日期：2009-02-06 00:00:00

abstract：:Extracellular concentration of nitrite (NO2-), an oxidized product of nitric oxide (NO), was measured consecutively in the dorsal region of the rat suprachiasmatic nucleus (SCN) by means of in vivo microdialysis. The NO2- concentrations in the dialysates showed robust circadian rhythm under a 12:12 h light/dark cycle ...

journal_title：Neuroscience letters

authors： Mitome M,Shirakawa T,Oshima S,Nakamura W,Oguchi H

更新日期：2001-05-11 00:00:00

abstract：:The Amphibalanus amphitrite barnacle is a sessile marine crustacean and a major constituent of benthic as well as intertidal communities. A. amphitrite is also an important component of biofouling on artificial substrates. The role of nitric oxide (NO) was recently observed in the settlement of this species. In this w...

journal_title：Neuroscience letters

authors： Gallus L,Ferrando S,Gambardella C,Faimali M,Piazza V,Masini MA

更新日期：2013-10-25 00:00:00

abstract：:In order to assess functional skills of older adults, both timed up and go (TUG) test and gait speed (GS) test are well validated concerning their predictive capacities. However, the question remains unclear which one of these tests represents better the whole physical performance of older adults. The aim of this stud...

journal_title：Neuroscience letters

authors： Kubicki A

更新日期：2014-08-08 00:00:00

abstract：:Alternate serial 1 micron Durcupan resin sections of tiger salamander retina were stained with antisera against GABA and glycine using postembed immunocytochemical techniques. Although the vast majority of neurons were labeled by either GABA or glycine antiserum, a small percentage of presumed amacrine cells in the in...

journal_title：Neuroscience letters

authors： Yazulla S,Yang CY

更新日期：1988-12-19 00:00:00

abstract：:The association between the dopamine D4 receptor (DRD4) exon III polymorphism and personality trait of novelty seeking (NS) has been studied intensively. In the Japanese population, the results of the previous studies did not always coincide. In the present study, we investigated the association between the polymorphi...

journal_title：Neuroscience letters

authors： Tochigi M,Hibino H,Otowa T,Kato C,Marui T,Ohtani T,Umekage T,Kato N,Sasaki T

更新日期：2006-05-08 00:00:00

abstract：:A late hyperpolarization (LH) which follows low level to moderate synaptic stimulation of neurons in the hippocampal formation neurons was previously shown to consist primarily of a potassium conductance. The present experiments showed that when extracellular cesium was present in order to reduce anamolous rectificati...

journal_title：Neuroscience letters

authors： Thalmann RH

更新日期：1984-04-20 00:00:00

abstract：:In guinea pig hippocampal slices, 4-aminopyridine (4-AP) in concentrations of 100-500 microM reduced the adaptation of CA3 pyramidal neurons to depolarizing stimuli, resulting in a prolongation of repetitive firing during injection of long-lasting depolarizing currents. Concurrently, there was a decrease in the 'sag' ...

journal_title：Neuroscience letters

authors： Matsuda Y,Yoshida S,Fujimura K,Nakamura M

更新日期：1986-04-24 00:00:00

abstract：:Rats with their intra-lingual taste nerves (the chorda tympani and the glossopharyngeal nerve) sectioned were trained to avoid drinking 0.5 M NaCl solution by associating NaCl drinking with subsequent LiCl poisoning. The acquired learned aversion in these rats was abolished after ablations of the neocortical area for ...

journal_title：Neuroscience letters

authors： Yamamoto T,Takahashi T,Kawamura Y

更新日期：1981-07-02 00:00:00

abstract：:We have recently reported fluctuations in the expression of the period repeat sequence (pp2.5) during light-dark cycles in the suprachiasmatic nucleus (SCN) of rat [Neurosci. Lett., 122 (1991) 113-116]. Presently, we performed in situ hybridization which shows that the fluctuation of pp2.5 expression continues during ...

journal_title：Neuroscience letters

authors： Matsui M,Mitsui Y,Ishida N

更新日期：1993-12-12 00:00:00

abstract：:We investigated the mRNA expression of the various complement components in cultured mouse microglia and astrocytes by the reverse transcription and polymerase chain reaction. C1q, C2, C3, and C4 mRNAs were detected in microglial cultures. C3 and C4 mRNAs were found in astrocyte cultures. Microglia showed enhanced exp...

journal_title：Neuroscience letters

authors： Haga S,Aizawa T,Ishii T,Ikeda K

更新日期：1996-10-04 00:00:00

abstract：:The cardiovascular effects of intracerebroventricularly administered thyrotropin-releasing hormone (TRH) were studied in anesthetized rats in the presence of serotonin (5-HT) depletion induced by pretreatments with p-chloroamphetamine (PCA) or p-chlorophenylalanine (PCPA). After PCA the reduction of the whole brain 5-...

journal_title：Neuroscience letters

authors： Nurminen ML,Paakkari I,Seppälä T

更新日期：1991-06-24 00:00:00

abstract：:Myenteric neurons which innervate the mucosa of the guinea-pig ileum were characterized by combining retrograde transport of DiI in vitro with immunohistochemistry. Of DiI-labelled myenteric neurons, 43% were immunoreactive for calbindin and substance P, 25% were immunoreactive for calbindin alone, and 18% were immuno...

journal_title：Neuroscience letters

authors： Song ZM,Brookes SJ,Costa M

更新日期：1991-08-19 00:00:00

abstract：:The retrofacial nucleus project bilaterally to the ventrolateral nucleus of the tractus solitarius (vlNTS) as revealed by means of retrograde transport of the fluorescent markers, Fast blue (FB) and Diamidino yellow (DY), in the cat. Some of the neurons of the retrofacial nucleus send axonal ramifications to both vlNT...

journal_title：Neuroscience letters

authors： Portillo F,Pásaro R

更新日期：1987-05-19 00:00:00

abstract：:Using functional near-infrared spectroscopy (fNIRS) we recorded prefrontal cortex (PFC) activation during positive, negative and neutral film clips, based on affective ratings according to their valence and arousal, to assess gender differences in cerebral activation in 15 male and 15 female volunteers. To record PFC ...

journal_title：Neuroscience letters

authors： Leon-Carrion J,Damas J,Izzetoglu K,Pourrezai K,Martín-Rodríguez JF,Barroso y Martin JM,Dominguez-Morales MR

更新日期：2006-07-31 00:00:00

abstract：:The longest central nervous system (CNS) specific isoform of the major myelin-associated inhibitor of neurite growth, Nogo-A, has previously been shown to be expressed largely in oligodendrocytes. Using an antibody raised against a recombinant fusion protein comprising amino acids 223-399 of Nogo-A, we show in this re...

journal_title：Neuroscience letters

authors： Liu H,Ng CE,Tang BL

更新日期：2002-08-16 00:00:00

abstract：:As a variant of peptide conantokin-T (con-T), con-T[M8Q] is derived from the venom of Conus tulipa. Our previous study has demonstrated that con-T[M8Q] selectively targets N-methyl-d-aspartate receptor (NMDAR) NR2B subunit. In the present study, we determined the effects of con-T[M8Q] on the expression and development...

journal_title：Neuroscience letters

authors： Ren B,Zhou Z,Liu Z,Li B,Ou J,Dai Q

更新日期：2015-06-15 00:00:00

abstract：:The febrile responses induced by i.v. administrations of staphylococcal enterotoxin A (SEA) was mimicked by direct injection of SEA into the organum vasculosum laminae terminalis (OVLT) in unanesthetized rabbits. Compared with the febrile responses induced by i.v. injection of SEA, the OVLT route of injection required...

journal_title：Neuroscience letters

authors： Huang WT,Lin MT,Won SJ

更新日期：1997-10-24 00:00:00

abstract：:It is known that maternal deprivation induces hippocampal damage in the developing brains. In the present study, we examined the effects of melatonin on maternal deprivation-induced hippocampal damage both during and after stress-hyporesponsive period (SHRP). Hippocampal damage was examined by cresyl violet staining a...

journal_title：Neuroscience letters

authors： Tugyan K,Uysal N,Ozdemir D,Sonmez U,Pekcetin C,Erbil G,Sonmez A

更新日期：2006-05-01 00:00:00

abstract：:This study examined the effects of anterior pretectal nucleus (APT) conditioning stimulation on the activity of 92 functionally identified somatosensory brainstem neurons in the trigeminal (V) subnuclei oralis, interpolaris and caudalis of anesthetized rats. Conditioning stimulation inhibited most of the nociceptive n...

journal_title：Neuroscience letters

authors： Chiang CY,Chen IC,Dostrovsky JO,Sessle BJ

更新日期：1992-01-06 00:00:00

abstract：BACKGROUND:Parkinson's disease (PD) is the debilitating movement disorder, distinguished by dopaminergic and norepinephrinergic neurodegeneration. Apart from candidate gene mutations, several modifier loci have been reported to be associated with the disease manifestation. The Dopamine β-Hydroxylase (DBH) maintains cel...

journal_title：Neuroscience letters

authors： Ghosh A,Sadhukhan T,Giri S,Biswas A,Das SK,Ray K,Ray J

更新日期：2019-07-27 00:00:00

abstract：:The mouse dopamine D4 receptor gene was isolated from a genomic DNA library by plaque hybridization. The D4 receptor gene encoded an open reading frame consisting of 387 amino acids, interrupted by three introns. Distribution of the D4 receptor mRNA in brain regions and peripheral tissues of mice was examined by rever...

journal_title：Neuroscience letters

authors： Suzuki T,Kobayashi K,Nagatsu T

更新日期：1995-10-13 00:00:00

abstract：:The thickness of the dura mater was obtained from ultrasound probes on the skull and fast Fourier transform-Cepstrum through a probability process at various intracranial pressures (ICP), measured with pressure transducers, in 12 anesthetized dogs. There was a constant relationship between changes in thickness (micron...

journal_title：Neuroscience letters

authors： Kuchiwaki H,Inao S,Ishii N,Ogura Y,Sakuma N

更新日期：1995-09-22 00:00:00

abstract：:The presence and distribution of the presumed pan-neural marker protein gene product 9.5 (PGP)- and peptide-immunoreactive (ir) nerve fibers in alveolar walls of various species was investigated by light microscopic single and double staining immunohistochemistry. PGP-, tachykinin (TK)-, and calcitonin gene-related pe...

journal_title：Neuroscience letters

authors： Nohr D,Weihe E

更新日期：1991-12-16 00:00:00

abstract：:The effects of noradrenaline (NA) on synaptic responses in layer II of the entorhinal cortex (EC) were studied in normal and spontaneously epileptic mutant mice tottering using intracellular recording in a slice preparation. Neither the membrane properties of neurones nor the responses to NA differed between normal an...

journal_title：Neuroscience letters

authors： Pralong E,Magistretti PJ

更新日期：1994-09-26 00:00:00