Circadian regulation of per repeat mRNA in the suprachiasmatic nucleus of rat brain.

Abstract:

:We have recently reported fluctuations in the expression of the period repeat sequence (pp2.5) during light-dark cycles in the suprachiasmatic nucleus (SCN) of rat [Neurosci. Lett., 122 (1991) 113-116]. Presently, we performed in situ hybridization which shows that the fluctuation of pp2.5 expression continues during constant darkness conditions in the SCN of rat. The light exposure during subjective night but not subjective day triggered its elevated expression in a time-dependent manner which is parallel to that of c-fos expression. The results suggest the involvement of pp2.5 in the entrainment pathway of the circadian rhythm in rodent SCN.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Matsui M,Mitsui Y,Ishida N

doi

10.1016/0304-3940(93)90379-y

subject

Has Abstract

pub_date

1993-12-12 00:00:00

pages

189-92

issue

2

eissn

0304-3940

issn

1872-7972

pii

0304-3940(93)90379-Y

journal_volume

163

pub_type

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