Abstract:
:Noradrenaline (NA)- and neuropeptide Y (NPY)-containing cell bodies were found to occur in high numbers (>75% of all cells were positive) in the human superior cervical ganglion and distributed homogeneously throughout the ganglion and showed colocalisation. A few cell bodies were VIP-immunoreactive (-ir) (less than 5%) but none of them showed NOS-, CGRP- or SP-ir. Receptor mRNA expression was studied with RT-PCR. Total RNA from the superior cervical ganglion was successfully extracted. By using appropriate sense and antisense oligonucleotides designed from the published human sequences, we could show the presence of mRNA for the human NPY Y1, NPY Y2 and VPAC1 receptors but not CGRP1 receptor mRNA.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Tajti J,Möller S,Uddman R,Bodi I,Edvinsson Ldoi
10.1016/s0304-3940(99)00115-9keywords:
subject
Has Abstractpub_date
1999-03-26 00:00:00pages
121-4issue
2-3eissn
0304-3940issn
1872-7972pii
S0304-3940(99)00115-9journal_volume
263pub_type
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