Serotonergic involvement in the cardiovascular stimulation by thyrotropin-releasing hormone (TRH) in anesthetized rats.

abstract：:We investigated the secretion of amyloid beta-protein (beta AP) in a mouse neuronal cell line SN49. SN49 cells stably transfected with mouse beta-amyloid precursor protein (APP) 695 cDNA released approximately three times greater amounts of a 4 kDa protein immunoreactive with anti-beta AP antibodies than untransfected...

journal_title：Neuroscience letters

authors： Araki W,Kunishita T,Takahashi K,Ikeda S,Tabira T

更新日期：1994-02-14 00:00:00

abstract：:Previous studies have demonstrated that isoflurane, a commonly used volatile anesthetic, can induce widespread apoptosis in the neonatal animal brains and result in persistent cognitive impairment. Isoflurane-induced cytosolic Ca(2+) overload and activation of mitochondrial pathway of apoptosis may be involved in this...

journal_title：Neuroscience letters

authors： Li Y,Wang F,Liu C,Zeng M,Han X,Luo T,Jiang W,Xu J,Wang H

更新日期：2013-06-17 00:00:00

abstract：:Slightly suprathreshold magnetic stimuli were delivered over the left scalp while a normal human subject attended a sensory signal which called for a motor response of right fingers in a reaction time paradigm. The cortico-motoneuronal systems of the two muscles producing finger extension disclosed a remarkable physio...

journal_title：Neuroscience letters

authors： Tomberg C

更新日期：1995-02-06 00:00:00

abstract：:In order to search for compounds mimicking the neurotrophic activities, a series of substances possessing the guanidine group of isaxonine (2-isopropylamino-pyrimidine), were synthesized and tested for their ability to induce neurite outgrowth in cultures of explants of rat dorsal root ganglia. It is reported that sev...

journal_title：Neuroscience letters

authors： Lehmann S,Quirosa-Guillou C,Becherer U,Thal C,Zanetta JP

更新日期：1993-04-02 00:00:00

abstract：:The localization of amyloid beta protein (A beta), A beta 40, A beta 42, and transthyretin (TTR) was investigated immunohistochemically in the autopsied human kidney, using polyclonal antibodies against TTR, A beta and C-terminal end-specific antibodies against A beta 40 and 42. Immunoreactivities of A beta and A beta...

journal_title：Neuroscience letters

authors： Tsuzuki K,Fukatsu R,Hayashi Y,Yoshida T,Sasaki N,Takamaru Y,Yamaguchi H,Tateno M,Fujii N,Takahata N

更新日期：1997-02-07 00:00:00

abstract：:Recent studies have shown that PLA2G6 is a causative gene for PARK14-linked autosomal recessive early-onset complicated dystonia-parkinsonism, early-onset parkinsonism with frontotemporal dementia and autosomal recessive early-onset Parkinsonism without added complicated clinical features. In order to investigate the ...

journal_title：Neuroscience letters

authors： Tian JY,Tang BS,Shi CH,Lv ZY,Li K,Yu RL,Shen L,Yan XX,Guo JF

更新日期：2012-04-18 00:00:00

abstract：:To elucidate the relationship between glutamatergic and dopaminergic transmissions, the effects of antisense oligodeoxynucleotide (aODN) to mRNA of NR1 subunit of N-methyl-D-aspartate (NMDA) receptors on the expression of dopamine D(2) receptors (DRD(2)) were examined. Rats received continuous intracerebroventricular ...

journal_title：Neuroscience letters

authors： Murata M,Suzuki M,Tanaka K,Tajiri K,Emori K,Kurachi M

更新日期：2002-12-19 00:00:00

abstract：:It is known that maternal deprivation induces hippocampal damage in the developing brains. In the present study, we examined the effects of melatonin on maternal deprivation-induced hippocampal damage both during and after stress-hyporesponsive period (SHRP). Hippocampal damage was examined by cresyl violet staining a...

journal_title：Neuroscience letters

authors： Tugyan K,Uysal N,Ozdemir D,Sonmez U,Pekcetin C,Erbil G,Sonmez A

更新日期：2006-05-01 00:00:00

abstract：:To study the spatial frequency (SF) effects on cortical face processing, we recorded magnetoencephalographic responses in seven healthy subjects to upright and inverted human faces. Four face types were used, including original (broad-band SF, BSF), low SF (LSF, <5 cycles/face), middle SF (MSF, 5-15 cycles/face), and ...

journal_title：Neuroscience letters

authors： Hsiao FJ,Hsieh JC,Lin YY,Chang Y

更新日期：2005-05-20 00:00:00

abstract：:Tyrosine phosphorylation is an important means for regulating post-ischemic signal transduction. In this article, brain ischemia was induced by four-vessel occlusion, and the effect of ischemia/reperfusion on proline-rich tyrosine kinase 2 (Pyk2) was studied. Tyrosine phosphorylation of Pyk2 in Sprague-Dawley rat hipp...

journal_title：Neuroscience letters

authors： Liu Y,Zhang GY,Hou XY,Xu TL

更新日期：2003-09-18 00:00:00

abstract：:Caffeine is a widely consumed substance that elicits psychomotor stimulant effects and also displays addictive properties. In order to assess the effect of caffeine on striatal neuropeptide mRNA expression, male rats were injected (i.p.) with caffeine at 20, 40 or 80 mg/kg of body weight twice daily for 9 consecutive ...

journal_title：Neuroscience letters

authors： Datta U,Noailles PA,Kraft M,Zhang Y,Angulo JA

更新日期：1997-08-01 00:00:00

abstract：:An anti-Fos protein antiserum was used to elucidate the diurnal expression of Fos protein in the normal and degenerate rd/rd mice retina. We have found that Fos expression is stimulated in cells of both inner nuclear layer (INL) and ganglion cell layer (GCL) at the onset of light period and reaches its maximum after 2...

journal_title：Neuroscience letters

authors： Huerta JJ,Llamosas MM,Cernuda-Cernuda R,García-Fernández JM

更新日期：1997-09-05 00:00:00

abstract：:The crossed thalamo-cortical and cortico-thalamic connections of the mouse are drawn using the tracer wheat germ agglutinin-horseradish peroxidase. After injections in the frontal cortex of the right hemisphere cells labeled retrogradely and axons labeled anterogradely are observed in the thalamus ipsilateral and cont...

journal_title：Neuroscience letters

authors： Carretta D,Sbriccoli A,Santarelli M,Pinto F,Granato A,Minciacchi D

更新日期：1996-02-02 00:00:00

abstract：:We investigated changes in the corticospinal pattern of activity in healthy volunteers during sustained noxious and non-noxious mechanical stimulation of the first hand digit, resulting from active (self-stimulation) or passive (externally-induced) pressing against a sharp or blunted tip. The results indicate that, in...

journal_title：Neuroscience letters

authors： Fadiga L,Craighero L,Dri G,Facchin P,Destro MF,Porro CA

更新日期：2004-05-06 00:00:00

abstract：:Bilaterally symmetrical periventricular lesions at preoptic-anterior hypothalamic levels of anteroventral third ventricle (AV3V) produce adipsia without aphagia in the rat. Sweet palatable fluids, but not water, are drunk during the adipsic period and if hydration is thus maintained, voluntary ingestion of plain water...

journal_title：Neuroscience letters

authors： Buggy J,Johnson AK

更新日期：1977-07-01 00:00:00

abstract：:This study aimed to determine whether neuropathic pain is associated with a plasticity change in the number of synapses in the spinal dorsal horn. 12 normal adult SD rats were randomly divided into two groups: 7 animals were subjected to unilateral loose ligation (to induce chronic constriction injury) of the sciatic ...

journal_title：Neuroscience letters

authors： Peng B,Lin JY,Shang Y,Yang ZW,Wang YP

更新日期：2010-12-03 00:00:00

abstract：:Five animals were used as their own controls for a replication on cats of earlier findings of facilitated paradoxical sleep (PS) after learning. The experiment was based on an instrumental conditioning with positive reinforcement and three-hour recordings of the subsequent sleep. Facilitation was observed as (a) an in...

journal_title：Neuroscience letters

authors： Lecas JC

更新日期：1976-12-01 00:00:00

abstract：:Experimental Scrapie in hamster is a simple, reproducible model of prion diseases that occur in humans and animals. Stereotaxic microinoculation (0.5 microliter) of the agent (263 K) into a specific cerebral structure (striatum) in hamster, previously developed in our group, gives the opportunity to further investigat...

journal_title：Neuroscience letters

authors： Grégoire N,Lebrun F,Fahn L,Salamon G,Nicoli J

更新日期：1993-12-12 00:00:00

abstract：:The autonomic nervous system (ANS) is implicated in maintaining homeostasis of the internal environment in mammals. Therefore, changes occurring in the ANS can cause alterations of physiological phenomena. Ethyl hexanoate (EH) is known as the aroma component of apples. To study the action of ethyl hexanoate on physiol...

journal_title：Neuroscience letters

authors： Horii Y,Fujisaki Y,Misonou Y,Fuyuki R,Nagai K

更新日期：2020-10-15 00:00:00

abstract：:The effects of various Flustra foliacea metabolites on different types of human neuronal nicotinic acetylcholine receptors (nAChRs) expressed in Xenopus oocytes were investigated. Whereas most of the compounds tested had a small blocking effect, one of them, deformylflustrabromine, selectively increased the current ob...

journal_title：Neuroscience letters

authors： Sala F,Mulet J,Reddy KP,Bernal JA,Wikman P,Valor LM,Peters L,König GM,Criado M,Sala S

更新日期：2005-01-10 00:00:00

abstract：:One of the clinical characteristics of psychogenic tremors (PT) is the disruption or transient cessation of tremor with distractive manoeuvres, including those involving the performance of voluntary movements with the contralateral hand. Seven patients with PT, 11 patients with Parkinson's disease (PD), 10 patients wi...

journal_title：Neuroscience letters

authors： Kumru H,Valls-Solé J,Valldeoriola F,Marti MJ,Sanegre MT,Tolosa E

更新日期：2004-11-11 00:00:00

abstract：:The terpene lactones of Ginkgo biloba extract, namely ginkgolides (A, B, and C) and bilobalide, possess antioxidant, anti-inflammatory, and neuroprotective effects. They are widely prescribed for the treatment of cerebral dysfunctions and neurological impairments. In addition, they demonstrate antagonistic action at t...

journal_title：Neuroscience letters

authors： Nishimon S,Yamaguchi M,Muraki H,Sakai N,Nishino S

更新日期：2020-03-23 00:00:00

abstract：:Crayfish muscle fibres were voltage-clamped at E = -80 mV membrane potential and superfused for about 10 min with Li+ saline (Na+ replaced by Li+) which contained picrotoxin to block inhibitory post-synaptic currents. Addition of veratridine (100 mumol/l) caused intense fluctuations in the voltage clamp current within...

journal_title：Neuroscience letters

authors： Finger W,Martin C

更新日期：1987-12-16 00:00:00

abstract：:It has been shown that orexin neuropeptides contribute to morphine-induced physical dependence. The locus coeruleus (LC), which receives a dense extra-hypothalamic orexinergic projection, is a key brain region implicated in the expression of somatic signs of morphine withdrawal syndrome. The aim of the present study i...

journal_title：Neuroscience letters

authors： Azizi H,Mirnajafi-Zadeh J,Rohampour K,Semnanian S

更新日期：2010-10-04 00:00:00

abstract：:Chronic exposure of cultured canine cerebral vascular smooth muscle cells to ethanol (10-400 mM) for 1-5 days resulted in significant concentration-dependent elevation in resting intracellular free calcium ([Ca2+]i) levels. Preincubation of these cultured vascular cells with inhibitors of protein kinase C (PKC), staur...

journal_title：Neuroscience letters

authors： Zheng T,Li W,Zhang A,Altura BT,Altura BM

更新日期：1998-01-30 00:00:00

abstract：:Selective unilateral 6-hydroxydopamine lesion of the nigrostriatal dopaminergic neurones in rats resulted, 12 to 90 days later, in a marked increase in the number of neuropeptide Y (NPY)-immunoreactive perikarya in the ipsilateral deafferented striatum compared to the contralateral intact side in the same animal and t...

journal_title：Neuroscience letters

authors： Kerkerian L,Bosler O,Pelletier G,Nieoullon A

更新日期：1986-05-06 00:00:00

abstract：:Advanced aging is accompanied by a decline in visuospatial attention. Previous neuroimaging and electrophysiological studies have demonstrated dysfunction in specific brain areas related to visuospatial attention. However, it is still unclear how the functional connectivity between brain regions causes the decline of ...

journal_title：Neuroscience letters

authors： Li Y,Li C,Wu Q,Xu Z,Kurata T,Ohno S,Kanazawa S,Abe K,Wu J

更新日期：2015-06-15 00:00:00

abstract：:The distribution of cholecystokinin binding sites was studied by receptor autoradiography in the human striatum at midgestation, birth and adulthood. In the adult, cholecystokinin receptors are inhomogeneously distributed with patches of reduced labeling. In the caudate nucleus but not in the putamen these patches mat...

journal_title：Neuroscience letters

authors： Schiffmann SN,Goldman S,Heyman P,De Vuyst M,De Roy G,Vanderhaeghen JJ

更新日期：1992-07-06 00:00:00

abstract：:Presenilin 1 mutations are the major cause of autosomal dominant Alzheimer's disease. Here we present evidence that pathogenic mutations in putative transmembrane domains 1, 2, 3, 4 and 6 align along helical faces, thus supporting the view that these are indeed transmembrane domains, and suggesting that disruption of ...

journal_title：Neuroscience letters

authors： Hardy J,Crook R

更新日期：2001-06-29 00:00:00

abstract：:The volume density of mast cells was estimated in nerve end neuromas at various time-points after transection of the left sciatic nerve of 6-week-old mice. After an initial reduction in the amount of mast cells there was a steady increase with numerous cells in 6-month-old neuromas. The variation in amount of mast cel...

journal_title：Neuroscience letters

authors： Nennesmo I,Reinholt F

更新日期：1986-09-12 00:00:00