Corticospinal excitability during painful self-stimulation in humans: a transcranial magnetic stimulation study.

Abstract:

:We investigated changes in the corticospinal pattern of activity in healthy volunteers during sustained noxious and non-noxious mechanical stimulation of the first hand digit, resulting from active (self-stimulation) or passive (externally-induced) pressing against a sharp or blunted tip. The results indicate that, in order to press a finger onto a noxious stimulus with the same force generated to press onto a non-noxious one, the motor cortex adopts a peculiar strategy in terms of recruitment of motor units. This is reflected by an increase of corticospinal excitability (as revealed by motor potentials evoked by transcranial magnetic stimulation of the contralateral primary motor cortex) and EMG activity of agonist muscles, possibly related to an increase of motor unit synchronization.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Fadiga L,Craighero L,Dri G,Facchin P,Destro MF,Porro CA

doi

10.1016/j.neulet.2003.12.016

keywords:

subject

Has Abstract

pub_date

2004-05-06 00:00:00

pages

250-3

issue

1-3

eissn

0304-3940

issn

1872-7972

pii

S030439400301396X

journal_volume

361

pub_type

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