Changes in paradoxical sleep accompanying instrumental learning in the cat.

abstract：:The atypical serine/threonine protein kinase, a mammalian target of rapamycin (mTOR), is believed to be essential to the regulation of cell growth and the functions of the central nervous system. By using calcium imaging and patch-clamping techniques to study the role of this signaling pathway in the activity of cultu...

journal_title：Neuroscience letters

authors： Li RX,Yu XZ,Fu M,Zong M,Liu RL,Xie ZP

更新日期：2008-08-15 00:00:00

abstract：:A peptide consisting of residues 25-35 of the amyloid beta protein was applied to single neurons while monitoring membrane current by whole cell voltage clamp recording. Within minutes of direct exposure of a neuron to the amyloid beta peptide, a paroxysmal increase in neuronal membrane conductance was observed. This ...

journal_title：Neuroscience letters

authors： Simmons MA,Schneider CR

更新日期：1993-02-19 00:00:00

abstract：:The sensory neurons in the trigeminal ganglion which project to the muscles of mastication of the cat were studied using the retrograde transport of horseradish peroxidase. Horseradish peroxidase either was injected directly into the masticatory muscles or applied to the nerves supplying them. Numerous retrogradely la...

journal_title：Neuroscience letters

authors： Martin JW,Panneton WM

更新日期：1986-10-20 00:00:00

abstract：:The effects of morphine (0.2-200 micrograms/kg) administered into the brain stem via a vertebral artery on the somatosympathetic A- and C-reflexes evoked in a cardiac sympathetic nerve by electrical stimulation of somatic myelinated (A) and unmyelinated (C) afferent nerve fibers in anesthetized cats were examined. The...

journal_title：Neuroscience letters

authors： Kato J,Meguro K,Sato A,Sato Y

更新日期：1992-04-27 00:00:00

abstract：:The effects of intrathecal injections of morphine and other opioid receptor selective drugs were tested on urinary bladder contractions in the anesthetized rat. Morphine produced dose-related inhibition of bladder motility which was abolished by naloxone. This action was also observed with mu- and delta-opioid recepto...

journal_title：Neuroscience letters

authors： Dray A,Metsch R

更新日期：1984-06-01 00:00:00

abstract：:Ketogenic diets (KD) have shown beneficial effects in terms of anticonvulsant and anti-epileptogenic properties in several experimental models. However, few studies have investigated the consequences of KD with regards to the anti-epileptogenic and neuroprotective effects in kindling-induced seizures. Here, postnatal ...

journal_title：Neuroscience letters

authors： Jiang Y,Yang Y,Wang S,Ding Y,Guo Y,Zhang MM,Wen SQ,Ding MP

更新日期：2012-02-02 00:00:00

abstract：:We are constantly exposed to symbols such as traffic signs, emoticons in internet communication, or other abstract representations of objects as well as, of course, the written words. However, aside from the word reading, little is known about the way our brain responds when we read non-lexical iconic symbols. By usin...

journal_title：Neuroscience letters

authors： Shin YW,Kwon JS,Kwon KW,Gu BM,Song IC,Na DG,Park S

更新日期：2008-05-16 00:00:00

abstract：:Using a new polyclonal antibody against prostacyclin (PGI2)-synthase this enzyme was shown to be present in neuronal cells of bovine, rat and human brain, most abundantly in Purkinje cells of the cerebellum and cortical neurons, but not in glial cells. Western blots confirmed the specificity of the antibody and applie...

journal_title：Neuroscience letters

authors： Mehl M,Bidmon HJ,Hilbig H,Zilles K,Dringen R,Ullrich V

更新日期：1999-08-27 00:00:00

abstract：:Activation of the medial septum (MS) enhances the synchronized firing of pyramidal cells in the hippocampus. At least two distinct mechanisms might be recruited in this process: GABAergic inhibition of hippocampal inhibitory interneurons and cholinergic enhancement of pyramidal cell excitability. In the present study,...

journal_title：Neuroscience letters

authors： Ovsepian SV

更新日期：2006-01-23 00:00:00

abstract：:Small intestinal motility was monitored in conscious rats chronically fitted with intraparietal electrodes, the third and fourth weeks after intraperitoneal administration of saline (controls) or N-(2-chloro-ethyl)-N-ethyl-2-bromobenzylamine (DSP-4, 50 mg/kg), a noradrenergic neurotoxin. Norepinephrine concentrations ...

journal_title：Neuroscience letters

authors： Fargeas MJ,Fioramonti J,Buéno L

更新日期：1988-08-01 00:00:00

abstract：:A replication-defective adenoviral vector containing the E. coli lacZ gene was directly injected into the ischemic or reperfused cerebral cortex of rats. An administration of adenoviral vector showed a slight to moderate expression of the lacZ gene in the cerebral cortex of the middle cerebral artery (MCA) region unti...

journal_title：Neuroscience letters

authors： Abe K,Setoguchi Y,Hayashi T,Itoyama Y

更新日期：1997-04-18 00:00:00

abstract：:Long-term adrenalectomy results in loss of neurones in the hippocampal formation of the adult rat. The effects of long-term adrenalectomy on spatial learning and exploratory behaviour in adrenalectomized (ADX), adrenalectomized normal weight gain (ADXNW), sham operated and naive control male Sprague-Dawley rats were i...

journal_title：Neuroscience letters

authors： Islam A,Henriksson B,Mohammed A,Winblad B,Adem A

更新日期：1995-07-14 00:00:00

abstract：:The analgesic effect of kappa partial agonist opioids (i.e. nalbuphine, pentazocine and butorphanol) is significantly greater in women. Recent evidence suggests that this sexual dimorphism may result from a naloxone-sensitive anti-analgesic effect that is activated along with, and summates with, the analgesic effect o...

journal_title：Neuroscience letters

authors： Gear RW,Gordon NC,Miaskowski C,Paul SM,Heller PH,Levine JD

更新日期：2003-11-06 00:00:00

abstract：:Central serotonergic neurotransmission has been implicated in the aetiology of ethanol tolerance and dependence. Cellular expression of the serotonin transporter and serotonin reuptake is modulated via a polymorphic, repetitive element in the 5'-flanking regulatory region of the serotonin transporter gene (5-HTTLPR). ...

journal_title：Neuroscience letters

authors： Türker T,Sodmann R,Goebel U,Jatzke S,Knapp M,Lesch KP,Schuster R,Schütz H,Weiler G,Stöber G

更新日期：1998-06-05 00:00:00

abstract：:Individual activation of nicotinic acetylcholine receptor (nAChR) or nitric oxide (NO) synthase in the dorsal facial area (DFA) increases blood flow of common carotid artery (CCA) supplying intra- and extra-cranial tissues. We investigated whether the activation of nAChR initiated the activation of NO synthase and gua...

journal_title：Neuroscience letters

authors： Gong CL,Leung YM,Huang YP,Lin NN,Hung YW,Lee TJ,Kuo JS

更新日期：2010-12-17 00:00:00

abstract：:The effect of antagonists on N-methyl-D-aspartate (NMDA)-induced response was investigated in isolated nucleus tractus solitarii (NTS) neurons freshly isolated from the rat using a conventional pathclamp technique. The NMDA-induced inward current consisted of an initial peak followed by a steady-state component. The c...

journal_title：Neuroscience letters

authors： Nakagawa T,Shirasaki T,Tateishi N,Murase K,Akaike N

更新日期：1990-05-31 00:00:00

abstract：:Intellectual disability (ID) is one of the most prevalent chronic developmental brain disorders or phenotype of syndromic ID, affecting nearly 1-2% of the general population worldwide. Over recent decades, tremendous effort and high-throughput platforms have been devised to explore the complex heterogeneity, numerous ...

journal_title：Neuroscience letters

authors： Chen C,Chen D,Xue H,Liu X,Zhang T,Tang S,Li W,Xu X

更新日期：2018-10-15 00:00:00

abstract：:In vitro pituitary adenylate cyclase activating polypeptide (PACAP) induces the expression of brain-derived neurotrophic factor (BDNF) via its specific receptor PAC1. Since BDNF has been implicated in learning paradigms and mice lacking functional PAC1 have deficits in hippocampus-dependent associative learning, we in...

journal_title：Neuroscience letters

authors： Zink M,Otto C,Zörner B,Zacher C,Schütz G,Henn FA,Gass P

更新日期：2004-04-22 00:00:00

abstract：:Recently, it has been hypothesized that the N-terminal portion of substance P (SP), SP(1-7), which results from the action of endopeptidase 24.11 (EC3.4.24.11), could be involved in mediating the depressor effects of baroreceptor afferent activation via its action on cells in the nucleus tractus solitarius (NTS). In t...

journal_title：Neuroscience letters

authors： Lasher RS,Lutz EM,Mulholland F,Sanderson R,Stewart JM,Bublitz C

更新日期：1990-09-04 00:00:00

abstract：:In urethane-anesthetized rats single neuronal activity was recorded in the laterodorsal tegmental nucleus (LDT), which has a dense complement of cholinergic neurons, and in the dorsal raphe and locus coeruleus for comparison. Most LDT neurons responded antidromically to stimulation of either one or more of several ros...

journal_title：Neuroscience letters

authors： Kayama Y,Ogawa T

更新日期：1987-06-26 00:00:00

abstract：:In control samples, intense acoustic "go" stimuli accelerate the central and peripheral motor processes that compose simple reaction time movements. The goal of the current study was to determine whether movements that are initiated to intense acoustic cues facilitate simple reaction times in (1) adults with chronic s...

journal_title：Neuroscience letters

authors： Coombes SA,Janelle CM,Cauraugh JH

更新日期：2009-03-13 00:00:00

abstract：:Fish glial cells were obtained from cultivated segments of the optic nerve and raised in vitro. Two types of cells were identified as astrocyte- and oligodendrocyte-like glia by the monoclonal antibody Mab O1 (specific for oligodendrocytes) and the rabbit serum anti-goldfish glial fibrillary acidic protein (anti-G-GFA...

journal_title：Neuroscience letters

authors： Bastmeyer M,Beckmann M,Nona SM,Cronly-Dillon JR,Stuermer CA

更新日期：1989-06-19 00:00:00

abstract：:A previous study suggested that adults with greater motor difficulties demonstrated less adaptation under a regular error feedback schedule (gain=1:1) but reached a similar level of adaptation compared to controls when feedback was enhanced (gain=1:2). In light of these findings, the present study examined inter-limb ...

journal_title：Neuroscience letters

authors： Bo J,Lee CM

更新日期：2017-07-27 00:00:00

abstract：:Vesicular glutamate transporters (VGLUTs) are responsible for loading glutamate into synaptic vesicles. Altered VGLUT protein expression has been suggested to affect quantal size and glutamate release under both physiological and pathological conditions. In this study, we investigated mRNA and protein expression level...

journal_title：Neuroscience letters

authors： Van Liefferinge J,Jensen CJ,Albertini G,Bentea E,Demuyser T,Merckx E,Aronica E,Smolders I,Massie A

更新日期：2015-03-17 00:00:00

abstract：:Recent research in social neuroscience proposes a link between mirror neuron system (MNS) and social cognition. The MNS has been proposed to be the neural mechanism underlying action recognition and intention understanding and more broadly social cognition. Pre-motor MNS has been suggested to modulate the motor cortex...

journal_title：Neuroscience letters

authors： Puzzo I,Cooper NR,Vetter P,Russo R,Fitzgerald PB

更新日期：2009-12-25 00:00:00

abstract：:Rapid balance reactions such as compensatory reach to grasp represent important response strategies following unexpected loss of balance. While it has been assumed that early corrective actions arise from subcortical networks, recent research has prompted speculation about the potential role of cortical involvement. W...

journal_title：Neuroscience letters

authors： Bolton DAE,Patel R,Staines WR,McIlroy WE

更新日期：2011-10-24 00:00:00

abstract：:Noxious peripheral stimulation induces the expression of various proto-oncogenes in rat spinal neurons. However, proto-oncogene expression seems to differ depending on the mode of the stimulus. Here, we report that noxious cutaneous ultraviolet (UV) irradiation results in a nearly 8-fold increase in junD mRNA levels i...

journal_title：Neuroscience letters

authors： Gillardon F,Wiesner RJ,Zimmermann M

更新日期：1992-02-17 00:00:00

abstract：:It is well known that the CaVα2δ auxiliary subunit regulates the density of high voltage-activated Ca2+ channels in the plasma membrane and that alterations in their functional expression might have implications in the pathophysiology of diverse human diseases such as neuropathic pain. However, little is known concern...

journal_title：Neuroscience letters

authors： González-Ramírez R,Martínez-Hernández E,Sandoval A,Gómez-Mora K,Felix R

更新日期：2018-04-23 00:00:00

abstract：:Urotensin I-like immunoreactivity (UILI), in different localization from that of corticotropin releasing factor-like immunoreactivity (CRFLI), in the goldfish retina has been demonstrated by means of radioimmunoassay, high-performance liquid chromatography (HPLC) and immunohistochemistry. Radioimmunoassay showed 350 +...

journal_title：Neuroscience letters

authors： Sakanaka M,McMaster D,Chohan K,Shibasaki T,Stell WK,Lederis K

更新日期：1987-04-23 00:00:00

abstract：:Both preischemic hyperglycemia and reduction of manganese superoxide dismutase activity are known to enhance neuronal death induced by transient cerebral ischemia. Transcriptional factor hypoxia-inducible factor 1 (HIF-1) regulates multiple downstream genes that modulate cell metabolism, survival, death, angiogenesis,...

journal_title：Neuroscience letters

authors： Bullock JJ,Mehta SL,Lin Y,Lolla P,Li PA

更新日期：2009-06-05 00:00:00