Urotensin I-like immunoreactivity in amacrine cells of the goldfish retina.

Abstract:

:Urotensin I-like immunoreactivity (UILI), in different localization from that of corticotropin releasing factor-like immunoreactivity (CRFLI), in the goldfish retina has been demonstrated by means of radioimmunoassay, high-performance liquid chromatography (HPLC) and immunohistochemistry. Radioimmunoassay showed 350 +/- 40 pg/mg prot. of UILI in goldfish retina extracts. The immunoreactive material present in the retina was also characterized by reversed phase HPLC. Some of the UILI co-eluted with synthetic carp UI, though the HPLC experiments suggested the existence of other UILI substance(s) with less hydrophobicity than synthetic UI. By immunohistochemistry, UILI and CRFLI were seen in different amacrine cells of the goldfish retina. It is suggested that UI may be involved in the fish visual transmission system together with CRF and other neuropeptides.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Sakanaka M,McMaster D,Chohan K,Shibasaki T,Stell WK,Lederis K

doi

10.1016/0304-3940(87)90199-6

subject

Has Abstract

pub_date

1987-04-23 00:00:00

pages

96-100

issue

1

eissn

0304-3940

issn

1872-7972

pii

0304-3940(87)90199-6

journal_volume

76

pub_type

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