The vagal origin of preganglionic fibers containing nitric oxide synthase in the guinea-pig heart.

Abstract:

:The origin of nerve fibers projecting to the guinea pig heart that contain nitric oxide synthase (NOS) were studied by unilateral cervical vagotomy. Three kinds of NOS-immunoreactive (NOS-ir) nerve fibers are distributed in the control guinea pig heart: the sparse network covering the right atrium, the basket-like endings around intracardiac neuronal cell bodies in the small ganglia located in the left atrium and the interatrial septum, and the axons situated in the septal region. The sparse network in the right atrium did not change after vagotomy of right or left side. In the whole mount preparations of right atrium, we often traced labeled axons from the somata to join the network covering the right atrium. Therefore, most of this network of labeled fibers must be of intrinsic origin. Because the basket-like endings around neuronal cell bodies in the ganglia in the left atrium and the septum disappeared completely after vagotomy of left side, we conclude that they are parasympathetic preganglionic fibers originating from the left vagus nerve. NOS-ir cell bodies and the positive fibers in the atrioventricular nodal region survived after vagotomy. All of such nerve fibers were unmyelinated axons. Therefore, they seem to be the postganglionic fibers arising from the ganglia located in the left atrium or the septum.

journal_name

Neurosci Lett

journal_title

Neuroscience letters

authors

Tanaka K,Chiba T

doi

10.1016/s0304-3940(98)00568-0

subject

Has Abstract

pub_date

1998-08-14 00:00:00

pages

135-8

issue

2

eissn

0304-3940

issn

1872-7972

pii

S0304394098005680

journal_volume

252

pub_type

杂志文章
  • DNA versus RNA oxidation in Parkinson's disease: Which is more important?

    abstract:BACKROUND:8-hydroxy-2 deoxyguanosine (8-OHdG) and the 8-hydroxyguanosine (8-OHG) are the most widely used biomarkers of nucleoside oxidation affecting DNA and RNA and are considered reliable markers of oxidative stress. Increased levels of these markers are found in the various biological fluids of patients with neurod...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2017.09.048

    authors: Gmitterová K,Gawinecka J,Heinemann U,Valkovič P,Zerr I

    更新日期:2018-01-01 00:00:00

  • Inhibition of GABA and benzodiazepine receptor binding by penicillins.

    abstract::Penicillins are thought to be GABA receptor antagonists. In order to determine the affinities of various penicillin derivatives for the GABA receptor, their potencies as inhibitors of specific [3H]GABA binding to rat brain membranes were investigated. All investigated penicillins inhibit specific [3H]GABA binding, wit...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(80)90302-x

    authors: Antoniadis A,Müller WE,Wollert U

    更新日期:1980-07-01 00:00:00

  • Arginine vasotocin activates phosphoinositide signal transduction system and potentiates N-acetyltransferase activity in the rat pineal gland.

    abstract::The pineal gland is innervated by pinealopetal peptidergic fibers originating in the hypothalamic nuclei which release arginine vasopressin (AVP) and arginine vasotocin (AVT) from their endings. Since the mechanism of AVT action on the pineal signal transduction and melatonin synthesis has not been determined so far, ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(99)00066-x

    authors: Novotná R,Jác M,Hájek I,Novotný I

    更新日期:1999-03-05 00:00:00

  • Interferon-alpha, beta and -gamma induce (2'-5') oligoadenylate synthetase in cultured mouse brain cells.

    abstract::Basal and interferon (IFN)-induced levels of (2'-5') oligoadenylate synthetase activity were measured in astrocyte cultures from the mouse cerebral cortex, in neurone-enriched and mixed cerebellar cultures, and in two continuous neural cell lines by a radioimmunoassay procedure. All untreated cultures contained measur...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(86)90293-4

    authors: Hirsch MR,Cailla H,Wietzerbin J,Goridis C

    更新日期:1986-04-11 00:00:00

  • The influence of cerebrospinal fluid turnover on age-related changes in cerebrospinal fluid protein concentrations.

    abstract::Studies have shown that ageing and several neurological diseases of the central nervous system are often accompanied with increase in concentrations of many cerebrospinal fluid (CSF) proteins. However, few studies have actually looked into the mechanisms behind the increase in CSF protein concentrations. In this study...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2010.04.015

    authors: Chen CP,Chen RL,Preston JE

    更新日期:2010-06-07 00:00:00

  • Periaqueductal gray matter stimulation-produced analgesia in diabetic rats.

    abstract::The effect of diabetes on periaqueductal gray matter (PAG) stimulation-produced analgesia (SPA) was examined in rats. PAG SPA was assessed using the tail-pinch test. PAG stimulation produced marked analgesia in both naive and diabetic rats. Furthermore, the degree of PAG SPA did not differ between naive and diabetic r...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(92)90609-b

    authors: Kamei J,Aoki T,Kasuya Y

    更新日期:1992-08-03 00:00:00

  • The neurogenic contribution to synovial leucocyte infiltration and other outcome measures in a guinea pig model of arthritis.

    abstract::A neurogenic contribution to joint inflammation has been demonstrated in rat adjuvant arthritis, however as inflammatory mechanisms vary between species it is unclear whether these observations can be applied more generally. The aim of this study was to assess the neurogenic contribution to cellular infiltration and o...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(00)01790-0

    authors: Hood VC,Cruwys SC,Urban L,Kidd BL

    更新日期:2001-02-23 00:00:00

  • Mental motor imagery and the body schema: evidence for proprioceptive dominance.

    abstract::Previous studies have demonstrated that both visual and proprioceptive feedback influence motor control. The relative contributions of these sensory modalities to the on-line computation of body position--that is, the body schema--remain unclear. We report a study designed to explore the roles of vision and propriocep...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2004.07.053

    authors: Shenton JT,Schwoebel J,Coslett HB

    更新日期:2004-11-03 00:00:00

  • Multi-system state shifts and cognitive deficits induced by chronic morphine during abstinence.

    abstract::Chronic morphine administration induces neural plasticity followed by withdraw. And clinic observation indicates that obvious cognitive deficits are found during withdrawal. However, current neural substrates that regulate dysfunction in withdrawal are unknown. In our studies, chronic morphine administration was used ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2016.10.057

    authors: Niu H,Zhang G,Li H,Zhang Q,Li T,Ding S,Wang L,Zhang Z,Qiao Y,Hu M

    更新日期:2017-02-15 00:00:00

  • Excitotoxic lesions of the lateral parabrachial nucleus do not prevent cholecystokinin-induced suppression of milk intake in rats.

    abstract::We examined the effect of lateral (visceral) and medial (gustatory) parabrachial nucleus (PBN) lesions on the suppression of milk intake induced with cholecystokinin (CCK) in 24 h food-deprived rats. Irrespective of CCK dose, each type of PBN lesion significantly elevated the consumption of milk. Neither medial nor la...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(03)00754-7

    authors: Trifunovic R,Reilly S

    更新日期:2003-09-11 00:00:00

  • Altered phospholipid molecular species and glycolipid composition in brain, liver and fibroblasts of Zellweger syndrome.

    abstract::We studied the altered molecular species of lipids in brain and liver tissues, and fibroblasts from patients with Zellweger syndrome (ZS). ZS cerebellum samples contained a higher amount of sphingomyelin with shorter chain fatty acids compared to that in normal controls. The amount of phosphatidylethanolamine (PE) was...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2013.07.045

    authors: Miyazaki C,Saitoh M,Itoh M,Yamashita S,Miyagishi M,Takashima S,Moser AB,Iwamori M,Mizuguchi M

    更新日期:2013-09-27 00:00:00

  • Complement gene expression in mouse microglia and astrocytes in culture: comparisons with mouse peritoneal macrophages.

    abstract::We investigated the mRNA expression of the various complement components in cultured mouse microglia and astrocytes by the reverse transcription and polymerase chain reaction. C1q, C2, C3, and C4 mRNAs were detected in microglial cultures. C3 and C4 mRNAs were found in astrocyte cultures. Microglia showed enhanced exp...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(96)13040-8

    authors: Haga S,Aizawa T,Ishii T,Ikeda K

    更新日期:1996-10-04 00:00:00

  • Pairing of forskolin and KCl increases differentiation of immortalized hippocampal neurons in a CREB Serine 133 phosphorylation-dependent and extracellular-regulated protein kinase-independent manner.

    abstract::Although cAMP response element binding protein (CREB)- and extracellular-regulated protein kinase (ERK)-mediated pathways have been linked to each other in neuronal differentiation, involvement of these in hippocampal neuronal cell line has not been defined. Using an immortalized hippocampal cell line, HiB5, we have t...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(01)01984-x

    authors: Son H,Kim KO,Kim JS,Chang MY,Lee SH,Lee YS

    更新日期:2001-07-27 00:00:00

  • Upregulation of glutamatergic transmission in anterior cingulate cortex in the diabetic rats with neuropathic pain.

    abstract::Peripheral neuropathic pain is a common complication in the diabetic patients, and the underlying central mechanism remains unclear. Forebrain anterior cingulate cortex (ACC) is critically involved in the supraspinal perception of physical and affective components of noxious stimulus and pain modulation. Excitatory gl...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2014.03.038

    authors: Li W,Wang P,Li H

    更新日期:2014-05-07 00:00:00

  • Progesterone modulates post-traumatic epileptogenesis through regulation of BDNF-TrkB signaling and cell survival-related pathways in the rat hippocampus.

    abstract::Female sex hormone, progesterone, in addition to seizure modifying activity is also known as a potential protective agent against various brain injury conditions. Considering the predisposal role of traumatic brain injury (TBI) on developing post-traumatic epilepsy (PTE), the effect of progesterone on post-traumatic e...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2019.134384

    authors: Ghadiri T,Vakilzadeh G,Hajali V,Khodagholi F

    更新日期:2019-09-14 00:00:00

  • Mismatch negativity (MMN) to speech sounds is modulated systematically by manual grip execution.

    abstract::Manual actions and speech are connected: for example, grip execution can influence simultaneous vocalizations and vice versa. Our previous studies show that the consonant [k] is associated with the power grip and the consonant [t] with the precision grip. Here we studied whether the interaction between speech sounds a...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2017.05.024

    authors: Tiainen M,Tiippana K,Paavilainen P,Vainio M,Vainio L

    更新日期:2017-06-09 00:00:00

  • Relations between early prespike magnetic field changes, interictal discharges, and return to basal activity in the neocortex of rabbits.

    abstract::To evaluate possible prespike field synchronizations, its relation to both interictal discharges and postspike return to baseline, penicillin-induced cortical interictal discharges were recorded in anaesthetized rabbits by magnetoencephalography (MEG) and electrocorticography (EcoG). Statistical parameters of spatial ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(00)01271-4

    authors: Zwiener U,Eiselt M,Giessler F,Nowak H

    更新日期:2000-08-04 00:00:00

  • The use of locomotor activity as a behavioral screen for neuronal damage following transient forebrain ischemia in gerbils.

    abstract::Five min bilateral carotid artery occlusion (BCO) in gerbils results in selective degeneration of neurons in the hippocampus, striatum and cortex, and an increase in spontaneous locomotor activity. These phenomena were examined to determine if an association could be made between the site or degree of neuronal degener...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(91)90762-i

    authors: Mileson BE,Schwartz RD

    更新日期:1991-07-08 00:00:00

  • Low extracellular magnesium ions induce lipid peroxidation and activation of nuclear factor-kappa B in canine cerebral vascular smooth muscle: possible relation to traumatic brain injury and strokes.

    abstract::The present study was designed to test the hypothesis that administration of low extracellular levels of magnesium ions ([Mg(2+)](o)) to primary cultured cerebral vascular smooth muscle cells will cause lipid peroxidation, degradation of IkappaB-alpha, and activation of nuclear transcription factor kappa B (NF-kappaB)...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/s0304-3940(03)00134-4

    authors: Altura BM,Gebrewold A,Zhang A,Altura BT

    更新日期:2003-05-08 00:00:00

  • Effects of voluntary exercise on anxiety-like behavior and voluntary morphine consumption in rat pups borne from morphine-dependent mothers during pregnancy.

    abstract::Exposure to morphine during pregnancy produced long-term effects in offspring behaviors. Recent studies have shown that voluntary exercise decreases the severity of anxiety behaviors in both morphine-dependent and withdrawn rats. Thus, the aims of the present study were to examine whether maternal exercise decreases p...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2014.06.026

    authors: Haydari S,Miladi-Gorji H,Mokhtari A,Safari M

    更新日期:2014-08-22 00:00:00

  • Increased presence of matrix metalloproteinases 2 and 9 in short- and long-term experimental herpes simplex virus encephalitis.

    abstract::Herpes simplex virus encephalitis (HSVE) causes elevated morbidity and mortality despite antiviral treatment. Virus-independent mechanisms may perpetuate brain damage. Matrix metalloproteinases (MMPs) target extracellular matrix components. This study describes the protein and mRNA expression of MMP2 and MMP9 in exper...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2004.06.064

    authors: Martínez-Torres FJ,Wagner S,Haas J,Kehm R,Sellner J,Hacke W,Meyding-Lamadé U

    更新日期:2004-09-30 00:00:00

  • Design principles of electrical synaptic plasticity.

    abstract::Essentially all animals with nervous systems utilize electrical synapses as a core element of communication. Electrical synapses, formed by gap junctions between neurons, provide rapid, bidirectional communication that accomplishes tasks distinct from and complementary to chemical synapses. These include coordination ...

    journal_title:Neuroscience letters

    pub_type: 杂志文章,评审

    doi:10.1016/j.neulet.2017.09.003

    authors: O'Brien J

    更新日期:2019-03-16 00:00:00

  • Ultrastructural studies of medullary synaptic inputs to vasopressin-immunoreactive neurons in the supraoptic nucleus of the rat hypothalamus.

    abstract::Direct projections from the A1/C1 catecholaminergic cell group in the caudal ventrolateral medulla oblongata to neurons containing vasopressin (VP) in the supraoptic nucleus (SON) were studied electron microscopically by a double-labeling technique which combines anterograde tracing after injection of wheat germ agglu...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(92)90828-u

    authors: Shioda S,Shimoda Y,Nakai Y

    更新日期:1992-12-14 00:00:00

  • Binding of omega-conotoxin to receptor sites associated with the voltage-sensitive calcium channel.

    abstract::The binding of radioiodinated omega-conotoxin GVIA, a probable Ca channel antagonist, to synaptic plasma membranes of rat brain was examined. Two kinds of specific binding sites were found with apparent dissociation constants of 10 pM and 0.5 nM and maximum binding capacities of 0.5 and 3.4 pmol/mg prot., respectively...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(86)90559-8

    authors: Abe T,Koyano K,Saisu H,Nishiuchi Y,Sakakibara S

    更新日期:1986-11-11 00:00:00

  • Is perception of self-motion speed a necessary condition for intercepting a moving target while walking?

    abstract::While it has been shown that the Global Optic Flow Rate (GOFR) is used in the control of self-motion speed, this study examined its relevance in the control of interceptive actions while walking. We asked participants to intercept approaching targets by adjusting their walking speed in a virtual environment, and predi...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2014.02.030

    authors: Morice AH,Wallet G,Montagne G

    更新日期:2014-04-30 00:00:00

  • The inactivation of extracellular signal-regulated kinase by glucagon-like peptide-1 contributes to neuroprotection against oxidative stress.

    abstract::Glucagon-like peptide-1 (GLP-1), an insulinotropic peptide secreted from enteroendocrine cells, has been known to have a neuroprotective effect. However, it is not fully understood the intracellular mediator of GLP-1 signaling in neuronal cells. In the present study, we examined the change in intracellular signaling o...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2016.01.052

    authors: Nakajima S,Numakawa T,Adachi N,Yoon HS,Odaka H,Ooshima Y,Kunugi H

    更新日期:2016-03-11 00:00:00

  • Analysis of a neuronal antigen (Hu) expression in the developing rat brain detected by autoantibodies from patients with paraneoplastic encephalomyelitis.

    abstract::Anti-Hu is an autoantibody that recognizes an antigen (Hu) highly restricted to neuronal nuclei. In the developing rat brain all neurons and the germinal cell layer were anti-Hu positive. Ependyma and choroid plexus were positive only in the early stages of development. The strongest expression of Hu was seen in the m...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/0304-3940(90)90314-y

    authors: Graus F,Ferrer I

    更新日期:1990-04-20 00:00:00

  • Meta-analysis of the insulin degrading enzyme polymorphisms and susceptibility to Alzheimer's disease.

    abstract::The association between insulin degrading enzyme (IDE) gene polymorphisms and Alzheimer's disease (AD) risk has been widely reported, but results were somewhat controversial. To assess the association between IDE polymorphisms and AD risk, a meta-analysis was performed. We systematically reviewed relevant studies retr...

    journal_title:Neuroscience letters

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.neulet.2013.01.051

    authors: Zhang Y,Wang B,Wan H,Zhou Q,Li T

    更新日期:2013-04-29 00:00:00

  • MDM2 antagonism by nutlin-3 induces death in human medulloblastoma cells.

    abstract::A critical component of the cellular stress response, the p53 tumor suppressor protein must be functional for many cancer therapies to be effective. Adjuvant therapies that augment p53 function are predicted to sensitize tumor cells to cancer therapies that rely upon p53 for their efficacy. Of those strategies current...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2012.02.022

    authors: Ghassemifar S,Mendrysa SM

    更新日期:2012-03-28 00:00:00

  • Preservation of cortical sortilin protein levels in MCI and Alzheimer's disease.

    abstract::The nerve growth factor (NGF) precursor protein proNGF is the predominant NGF moiety found in the human neocortex and exhibits pro-apoptotic properties when bound to the p75(NTR) neurotrophin receptor in the presence of sortilin, a Vps10p domain trafficking protein. Recently studies have shown that proNGF levels incre...

    journal_title:Neuroscience letters

    pub_type: 杂志文章

    doi:10.1016/j.neulet.2010.01.023

    authors: Mufson EJ,Wuu J,Counts SE,Nykjaer A

    更新日期:2010-03-08 00:00:00