Progesterone modulates post-traumatic epileptogenesis through regulation of BDNF-TrkB signaling and cell survival-related pathways in the rat hippocampus.

abstract：:Neuroimaging studies have identified cognitive tasks that can selectively activate specific parts of the brains. However, the subsequent effect of localized brain activation on the cognitive functioning remains unclear. We discovered that after being engaged in the novel picture encoding task to activate hippocampus f...

journal_title：Neuroscience letters

authors： Chan AS,Cheung M,Ho Y,Jing He W

更新日期：2000-04-07 00:00:00

abstract：:Four new tactile areas in the cerebellar cortex (crus I, crus II, paramedian lobule and uvula) have recently been described in the rat. Ipsilateral orofacial regions are chiefly represented in these areas. Our study of trigeminocerebellar afferents to these areas using the HRP retrograde tracing technique shows that t...

journal_title：Neuroscience letters

authors： Watson CR,Switzer RC 3rd

更新日期：1978-11-01 00:00:00

abstract：:Muscle vibration does not affect post-synaptic excitability of the corresponding motoneuronal pool, the concurrent depression of the monosynaptic reflex resulting from a pre-motoneuronal block of Ia spindle afferents. Indeed (1) both homonymous and heteronymous soleus responses (to electrical stimulation of the poster...

journal_title：Neuroscience letters

authors： Abbruzzese M,Minatel C,Faga D,Favale E

更新日期：1997-08-08 00:00:00

abstract：:Smoking cessation strategies are of prime medical importance. Despite availability of various pharmacological agents in combating addiction to nicotine, more effective medications are needed. Based on recent findings, the glutamatergic system in the brain may provide novel targets. Here, we evaluated the effects of ac...

journal_title：Neuroscience letters

authors： Rezvani AH,Tizabi Y,Slade S,Getachew B,Levin ED

更新日期：2018-03-06 00:00:00

abstract：:The neuron-specific phosphoprotein B-50 (GAP-43) is associated with neuritogenesis during development and regeneration. We monitored B-50 in cultured spinal neurons (fetal rat) with an enzyme-linked immunoadsorbent assay. B-50 levels increased from 24 to 72 h, then decreased. Other cultures, fixed at 24 h intervals an...

journal_title：Neuroscience letters

authors： van der Neut R,Oestreicher AB,Gispen WH,Bär PR

更新日期：1990-02-05 00:00:00

abstract：:We previously demonstrated the preventive effect of insulin-like growth factor 1 (IGF-1) on steroid myopathy in rats. However, the mechanism by which IGF-1 inhibits steroid myopathy remains unclear. Recent studies have revealed that glutamine synthetase (GS) is induced by glucocorticoid and may be related to the devel...

journal_title：Neuroscience letters

authors： Kimura K,Kanda F,Okuda S,Chihara K

更新日期：2001-04-20 00:00:00

abstract：:Gamma-band oscillations are related to sensory information processing and attention. To further illuminate the relationship of gamma-band activity and selective somatic attention, we have studied the effects of direction of attention on the stimuli of somatosensory evoked potentials. Responses during focused attention...

journal_title：Neuroscience letters

authors： Gobbelé R,Waberski TD,Schmitz S,Sturm W,Buchner H

更新日期：2002-07-12 00:00:00

abstract：:Whole-cell patch-clamp recordings (WCR) were made from sympathetic preganglionic neurons (SPN) in neonate rat spinal cord slices. SPN were identified histologically by filling them with the fluorescent dye Lucifer Yellow contained within the patch pipette solution. Current clamp recordings were obtained from SPN with ...

journal_title：Neuroscience letters

authors： Pickering AE,Spanswick D,Logan SD

更新日期：1991-09-16 00:00:00

abstract：:A predominant form of the GABAA/benzodiazepine receptor-Cl- channel complex is believed to consist of three different 48-55 kDa subunits (alpha, beta, gamma) with unknown stoichiometry. Plasmids containing the rat GABAA receptor cDNAs coding for alpha 1, beta 2, and gamma 2 were co-transfected, along with a plasmid en...

journal_title：Neuroscience letters

authors： Hamilton BJ,Lennon DJ,Im HK,Im WB,Seeburg PH,Carter DB

更新日期：1993-04-30 00:00:00

abstract：:Estrogen not only modulates nigrostriatal function but also developmental processes in the striatum. Recently, we have demonstrated the presence of the estrogen-synthesizing enzyme aromatase in the developing mouse striatum. This study is concerned with the expression of estrogen receptor-alpha/beta (ER) mRNA in the d...

journal_title：Neuroscience letters

authors： Küppers E,Beyer C

更新日期：1999-12-03 00:00:00

abstract：:The present study was carried out to examine whether γ-aminobutyric acid (GABA) receptor mechanisms are involved in the release of serotonin (5-hydroxytryptamine, 5-HT) in the subfornical organ (SFO) using intracerebral microdialysis techniques. Perfusion with the GABA receptor antagonists as well as agonists was perf...

journal_title：Neuroscience letters

authors： Takahashi M,Nomura M,Tanaka J

更新日期：2016-09-06 00:00:00

abstract：:The Calyx of Held (CoH) synapse is the largest synapse in mammals. It is located in the medial nucleus of the trapezoid body (MNTB) and forms part of the auditory pathway. Modest GABAergic signaling is present in the CoH before hearing onset, when glutamatergic transmission predominates. In mice, after postnatal day 1...

journal_title：Neuroscience letters

authors： Reyes-Haro D,Rosas-Arellano A,González-González MA,Mora-Loyola E,Miledi R,Martínez-Torres A

更新日期：2013-01-04 00:00:00

abstract：:DNA methylation of a CpG island located in intron 1 of the α-synuclein gene (SNCA) has been reported to play an essential role in the regulation of α-synuclein transcription, and probably has a close association with Parkinson's disease (PD). However, there is no simple and cost effective method to quantify DNA methyl...

journal_title：Neuroscience letters

authors： Song Y,Ding H,Yang J,Lin Q,Xue J,Zhang Y,Chan P,Cai Y

更新日期：2014-05-21 00:00:00

abstract：:In the last decade, several genes have been linked to Parkinson's disease (PD), including GIGYF2, ATP13A2 and GBA. To explore whether mutations in these genes contribute to development of PD in the Brazilian population, we screened 110 patients with early-onset PD. No clearly pathogenic mutations were identified in AT...

journal_title：Neuroscience letters

authors： Dos Santos AV,Pestana CP,Diniz KR,Campos M,Abdalla-Carvalho CB,de Rosso AL,Pereira JS,Nicaretta DH,de Carvalho WL,Dos Santos JM,Santos-Rebouças CB,Pimentel MM

更新日期：2010-11-19 00:00:00

abstract：:The suprachiasmatic nucleus (SCN) has been known as an oscillator of circadian rhythm and recently some reports suggested that excitatory amino acids were functioning in this nucleus. The purpose of this study is to measure the physiological amino acid content of this nucleus, to estimate the circadian variation in am...

journal_title：Neuroscience letters

authors： Takeuchi Y,Takahashi K

更新日期：1994-09-12 00:00:00

abstract：:The comorbidity between migraine and depression not only provides a major treatment challenge, but also represents a heavy burden on society. However, the relationship between depression and migraine and their molecular biological mechanisms remain unclear. This study investigated the effects of depression elicited by...

journal_title：Neuroscience letters

authors： Zhang M,Dai W,Liang J,Chen X,Hu Y,Chu B,Pan M,Dong Z,Yu S

更新日期：2013-09-13 00:00:00

abstract：:Neuronal nAChRs are pentameric transmembrane proteins which function as ligand-gated ion channels and are composed of multiple alpha and beta subunits. Nine neuronal nAChR alpha subunit genes (alpha2-alpha10) and three nAChR beta subunit genes (beta2-beta4) have been identified. nAChR subtypes are heteromers, composed...

journal_title：Neuroscience letters

authors： Danthi S,Boyd RT

更新日期：2006-05-29 00:00:00

abstract：:Rabbit retinal Müller cells were isolated by means of papaine and mechanical dissociation. These cells were shown to have a well preserved morphology and to preserve viability for many hours. Intense wheat germ agglutinin binding occurs on the photoreceptor side of Müller cells, especially in the microvillous region. ...

journal_title：Neuroscience letters

authors： Reichenbach A,Dettmer D,Brückner G,Neumann M,Birkenmeyer G

更新日期：1985-03-22 00:00:00

abstract：:Estrogen levels in rats are positively correlated with enhanced memory function and hippocampal dendritic spine density. There is much less work on the long-term effects of estradiol manipulation in preadolescent rats. The present work examined how injections of estradiol during postnatal days 19-22 (p19-22; preadoles...

journal_title：Neuroscience letters

authors： Wartman BC,Keeley RJ,Holahan MR

更新日期：2012-10-24 00:00:00

abstract：:The present experiment investigated cortical responses of native Italian subjects during reading of short sentences including semantic or morphosyntactic violations. Given the specificity of the Italian language in which the sequencing of words is relatively more free than in English or other languages, we investigate...

journal_title：Neuroscience letters

authors： Angrilli A,Penolazzi B,Vespignani F,De Vincenzi M,Job R,Ciccarelli L,Palomba D,Stegagno L

更新日期：2002-03-29 00:00:00

abstract：:Monosynaptic evoked field potentials (EPs) in response to paired-pulse stimulation (20 ms interval) were recorded in area CA1 and fascia dentata of the same animal in the course of development of a kindled focus in the CA1 region. A significant reduction of paired pulse depression in response to medium and high stimul...

journal_title：Neuroscience letters

authors： Kamphuis W,Gorter JA,Wadman WJ,Lopes da Silva FH

更新日期：1992-07-06 00:00:00

abstract：:Social psychological studies have shown that an experience of threat such as an encounter with death-related stimuli and social exclusion results in tuning toward positive emotional information. Neuroimaging studies have also begun to uncover the neural basis of threat coping, and in this literature, the activity of t...

journal_title：Neuroscience letters

authors： Yanagisawa K,Kashima ES,Moriya H,Masui K,Furutani K,Nomura M,Yoshida H,Ura M

更新日期：2013-09-27 00:00:00

abstract：:Immunohistochemical and biochemical investigations showed that significant protein nitration occurs in human gliomas, especially in grade IV glioblastomas at the level of astrocytes and oligodendrocytes and neurones. Enhanced alpha-tubulin immunoreactivity was co-present in the same elements in the glioblastomas. Prot...

journal_title：Neuroscience letters

authors： Fiore G,Di Cristo C,Monti G,Amoresano A,Columbano L,Pucci P,Cioffi FA,Di Cosmo A,Palumbo A,d'Ischia M

更新日期：2006-02-06 00:00:00

abstract：:Nucleus rostrolateralis is a distinctive diencephalic nucleus in some ray-finned fishes. In the osteoglossomorph Pantodon, it is a large ovoid nucleus with visual system connections. A topologically and cytoarchitectonically similar nucleus has been found in six species of non-osteoglossomorph fishes, two species of g...

journal_title：Neuroscience letters

authors： Saidel WM,Butler AB

更新日期：1997-06-20 00:00:00

abstract：:The spatial extents of hand-held objects can be perceived nonvisually by wielding them. This ability of effortful or dynamic touch to exploit the mass moments of an object to perceive its length was evaluated with a 40-years old right-handed woman with surgically treated Arnold-Chiari Type 1 Malformation and cervical ...

journal_title：Neuroscience letters

authors： Carello C,Kinsella-Shaw J,Amazeen EL,Turvey MT

更新日期：2006-09-25 00:00:00

abstract：:Nerve growth factor (NGF) protein has been implicated in alterations of cognitive function either following brain damage, selective lesions or aging. Groups of rats were given long-term (48 weeks) oral barbital treatment or tap water and following an extended period of abstinence (14 weeks) were tested for spatial lea...

journal_title：Neuroscience letters

authors： Wahlström G,Archer T,Lärkfors L

更新日期：1992-03-16 00:00:00

abstract：:Epileptic seizures are frequent in patients with glioma, and anticonvulsive treatment is often indicated. Glioma cells release glutamate via the Xc- antiporter system, which appears to be a major pathomechanism of glioma-associated seizures and excitotoxicity. In addition, the proliferation and survival of the tumor c...

journal_title：Neuroscience letters

authors： Mayer J,Kirschstein T,Resch T,Porath K,Krause BJ,Köhling R,Lange F

更新日期：2020-01-10 00:00:00

abstract：:Nuclear factor-kappa B (NF-kappa B) DNA binding factor is an inducible transcription factor that responds to various cellular signals. Levels of cortical NF-kappa B DNA binding activity were measured in a controlled lateral cortical impact model of traumatic brain injury (TBI) in rats. Using electrophoretic mobility s...

journal_title：Neuroscience letters

authors： Yang K,Mu XS,Hayes RL

更新日期：1995-09-08 00:00:00

abstract：:NTAK (neural- and thymus-derived activator for ErbB kinases), also known as neuregulin-2 (NRG2), is a member of the epidermal growth factor (EGF) family, which binds directly to ErbB3 and ErbB4, and transactivates ErbB2. NTAK/NRG2 is structurally homologous to NRG1. The biological function of NTAK/NRG2 still remains u...

journal_title：Neuroscience letters

authors： Nakano N,Kanekiyo K,Nakagawa T,Asahi M,Ide C

更新日期：2016-05-27 00:00:00

abstract：:Cannabinoid CB1 receptor (CB1R) is highly expressed in the mesocorticolimbic system and associated with drug craving and relapse. Clinical trials suggest that CB1R antagonists may represent new therapies for drug addiction. However, the downstream signaling of CB1R is not fully elucidated. In the present study, we inv...

journal_title：Neuroscience letters

authors： Zhang J,Wang N,Chen B,Wang Y,He J,Cai X,Zhang H,Wei S,Li S

更新日期：2016-09-06 00:00:00