Carbamazepine-induced blockade of induction of long-term potentiation in the perforant path-dentate gyrus pathway in chronically prepared rabbits.

abstract：:Various exogenous and endogenous steroids have been demonstrated to have both enhancing and inhibiting effects on ligand binding to the gamma-aminobutyric acid(A) receptor (GABAA receptor) in previous studies. In the present study we have explored the possibility that an additional class of synthetic steroidal compoun...

journal_title：Neuroscience letters

authors： Masonis AE,McCarthy MP

更新日期：1995-04-07 00:00:00

abstract：:The irreversible opiate antagonists beta-funaltrexamine (beta-FNA) and beta-chlornaltrexamine (beta-CNA) were injected into rat striatum. One day later, mu-opioid receptor binding, as assessed by receptor autoradiography, was abolished in the injected striatum, while [3H]spiperone binding remained largely unaffected. ...

journal_title：Neuroscience letters

authors： Morris BJ,Höllt V,Herz A

更新日期：1988-06-17 00:00:00

abstract：BACKGROUND:Diverse physiological and pathological functions of 27-hydroxycholesterol (27-OHC) were proved. However, cytotoxicity and potential influence of 27-OHC on cholesterol metabolism in neurons are unclear. DESIGN AND METHODS:In the vitro co-culture system, SH-SY5Y cells and C6 cells were applied to explore the ...

journal_title：Neuroscience letters

authors： Wang H,Yuan L,Ma W,Han J,Lu Y,Feng L,Xiao R

更新日期：2016-10-06 00:00:00

abstract：:Edaravone, an electron spin trapper with radical scavenging activity, has been shown to be effective in reducing infarct volume in humans following ischemic stroke. However, concerns of edaravone-induced renal toxicity have limited its clinical adoption. Previous work has demonstrated that edaravone produced significa...

journal_title：Neuroscience letters

authors： Connell BJ,Saleh MC,Kucukkaya I,Abd-El-Aziz AS,Khan BV,Saleh TM

更新日期：2014-02-21 00:00:00

abstract：:The thickness of the dura mater was obtained from ultrasound probes on the skull and fast Fourier transform-Cepstrum through a probability process at various intracranial pressures (ICP), measured with pressure transducers, in 12 anesthetized dogs. There was a constant relationship between changes in thickness (micron...

journal_title：Neuroscience letters

authors： Kuchiwaki H,Inao S,Ishii N,Ogura Y,Sakuma N

更新日期：1995-09-22 00:00:00

abstract：:The number of neurons in the primary motor cortex (MI) and the primary somatosensory cortex (SI) were estimated in the same locations of brains from sporadic amyotrophic lateral sclerosis (ALS) cases and controls. The number of MI and SI neurons and Betz cells were significantly decreased in the ALS cases as compared ...

journal_title：Neuroscience letters

authors： Mochizuki Y,Mizutani T,Shimizu T,Kawata A

更新日期：2011-09-26 00:00:00

abstract：:It is well established that calcium-dependent neurotransmitter release and exocytosis can be regulated by altering the cholesterol content of the plasma membrane. We have compared the influence of cholesterol depletion of synaptosomal plasma membrane by 15 mM methyl-beta-cyclodextrin (MCD) treatment on calcium-depende...

journal_title：Neuroscience letters

authors： Waseem TV,Kolos VA,Lapatsina LP,Fedorovich SV

更新日期：2006-09-11 00:00:00

abstract：:FasL has been shown to induce angiogenesis in vivo, however, the mechanism remains to be determined. We have previously shown that Fas ligation induces expression of chemokines such as interleukin-8 by human astrogliomas, which may partially explain the in vivo angiogenic property of FasL. Intercellular adhesion molec...

journal_title：Neuroscience letters

authors： Choi K,Benveniste EN,Choi C

更新日期：2003-11-27 00:00:00

abstract：:Fetal intrauterine growth restriction generates chronic hypoxia due to placental insufficiency. Despite the hemodynamic process of blood flow, redistributions are taking place in key organs such as the fetal brain during intrauterine growth restriction, in order to maintain oxygen and nutrients supply. The risk of sho...

journal_title：Neuroscience letters

authors： Hernández-Andrade E,Cortés-Camberos AJ,Díaz NF,Flores-Herrera H,García-López G,González-Jiménez M,Santamaría A,Molina-Hernández A

更新日期：2015-01-01 00:00:00

abstract：:Intracellular and extracellular recordings were obtained from layers II-III of slices of adult rat neocortex maintained in vitro. Excitatory postsynaptic potentials (EPSPs) and epileptiform discharges (paroxysmal depolarizing shifts, PDSs) were evoked in the presence of bicuculline methiodide. Responses were monitored...

journal_title：Neuroscience letters

authors： Burke JP,Hablitz JJ

更新日期：1994-06-06 00:00:00

abstract：:Melatonin modulates adult hippocampal neurogenesis in adult mice. Also, plasma melatonin levels and new neuron formation decline during aging probably causing cognitive alterations. In this study, we analyzed the impact of exogenous supplementation with melatonin in three key events of hippocampal neurogenesis during ...

journal_title：Neuroscience letters

authors： Ramírez-Rodríguez G,Vega-Rivera NM,Benítez-King G,Castro-García M,Ortíz-López L

更新日期：2012-11-14 00:00:00

abstract：:Hypoxic preconditioning (HP) is a novel strategy to make stem cells resistant to the ischemic environment they encounter after transplantation into injured tissue; this strategy improves survival of both the transplanted cells and the host cells at the injury site. Using both in vitro and in vivo injury models, we con...

journal_title：Neuroscience letters

authors： Oh JS,Ha Y,An SS,Khan M,Pennant WA,Kim HJ,Yoon DH,Lee M,Kim KN

更新日期：2010-03-26 00:00:00

abstract：:Advanced glycation end products (AGEs) in the brain were immunohistochemically examined in Alzheimer's disease (AD) and aging using anti-AGE antibody recognizing mainly carboxymethyllysine. AGE positive staining diffusely located in the neuronal perikarya of hippocampus and parahippocampus in AD and aged brains withou...

journal_title：Neuroscience letters

authors： Takedo A,Yasuda T,Miyata T,Mizuno K,Li M,Yoneyama S,Horie K,Maeda K,Sobue G

更新日期：1996-12-27 00:00:00

abstract：:The pigment of human substantia nigra, neuromelanin, has been thought to be derived from dopamine. To examine the genesis of neuromelanin, we advanced a new hypothesis that neuromelanin is formed by oxidation of dopamine and cysteinyldopamine. On the basis of this hypothesis, synthetic neuromelanins were obtained by t...

journal_title：Neuroscience letters

authors： Wakamatsu K,Ito S,Nagatsu T

更新日期：1991-09-30 00:00:00

abstract：:Extracellular noradrenaline was measured on-line in the cerebral cortex of the freely moving rat by microdialysis coupled to high performance liquid chromatography and electrochemical detection. High potassium concentrations in the perfusion fluid led to a strong increase, whereas tetrodotoxin led to almost undetectab...

journal_title：Neuroscience letters

authors： van Veldhuizen MJ,Feenstra MG,Boer GJ,Westerink BH

更新日期：1990-11-13 00:00:00

abstract：:Foetal rat mesencephalic dopamine-containing tissue was transplanted into the lateral ventricle of mice previously subjected to a 6-OHDA lesion of dopaminergic nerve terminals in the corpus striatum. The graft recipients were immunosuppressed by subcutaneous injections of 15-deoxyspergualin (DSG). Four weeks postgraft...

journal_title：Neuroscience letters

authors： Zhou J,Date I,Sakai K,Yoshimoto Y,Furuta T,Asari S,Ohmoto T

更新日期：1993-11-26 00:00:00

abstract：:The effect of lesions on nerve growth factor receptor (NGFr) immunoreactivity (IR) in motoneurons within the mature feline trigeminal motor nucleus was investigated. Ten days following complete unilateral retrogasserian trigeminal rhizotomy including transection of the trigeminal motor root, motoneurons within the ips...

journal_title：Neuroscience letters

authors： Kullas CD,Henry MA,Westrum LE,Johnson LR,Bothwell M

更新日期：1991-05-27 00:00:00

abstract：:By studying the binding of [3H]glycine and [3H]glutamate to rat synaptic membranes in the presence of 2-amino-5-phosphonovalerate (APV) and kynurenate (KYN) we have demonstrated that KYN is more potent than APV in displacing [3H]glycine, while an opposite order of potency was seen in displacing [3H]glutamate. Moreover...

journal_title：Neuroscience letters

authors： Danysz W,Fadda E,Wroblewski JT,Costa E

更新日期：1989-01-30 00:00:00

abstract：:Effects of sleep deprivation (SD) on one-trial recognition memory were investigated in rats using either a spontaneous novel-object or object-place recognition test. Rats were allowed to explore a field in which two identical objects were presented. After a delay period, they were placed again in the same field in whi...

journal_title：Neuroscience letters

authors： Ishikawa H,Yamada K,Pavlides C,Ichitani Y

更新日期：2014-09-19 00:00:00

abstract：:The present study examined the coordination dynamics of the head and center of mass (COM) using accelerometry in quiet 1 and 2 leg stance with and without vision. The root mean square jerk of effectors was greater in 1 leg stance and without vision, and was greater for the head in 2 leg stance and greater at the COM f...

journal_title：Neuroscience letters

authors： James EG

更新日期：2013-08-26 00:00:00

abstract：:Somatostatin and several analogues were injected into rat striatum and their effects on dopamine, serotonin and their metabolites were examined at 1 h. Somatostatin induced a dose-dependent increase in dopamine turnover in the ipsilateral striatum accompanied by a reduction in turnover on the contralateral side. There...

journal_title：Neuroscience letters

authors： Beal MF,Martin JB

更新日期：1984-02-24 00:00:00

abstract：:MicroRNA-146a (miRNA-146a) is an inducible, 22 nucleotide, small RNA over-expressed in Alzheimer's disease (AD) brain. Up-regulated miRNA-146a targets several inflammation-related and membrane-associated messenger RNAs (mRNAs), including those encoding complement factor-H (CFH) and the interleukin-1 receptor associate...

journal_title：Neuroscience letters

authors： Li YY,Cui JG,Dua P,Pogue AI,Bhattacharjee S,Lukiw WJ

更新日期：2011-07-20 00:00:00

abstract：:Apoptotic protease activating factor-1 (Apaf-1) is a critical regulator of apoptosis and a crucial part of the apoptosome that is assembled in response to several cellular stresses like hypoxia. We have previously shown that hypoxia results in increased influx of nuclear Ca(2+) and increased expression of nuclear apop...

journal_title：Neuroscience letters

authors： Ashraf QM,Mishra OP,Delivoria-Papadopoulos M

更新日期：2007-03-30 00:00:00

abstract：:We investigated microvascular damage in areas with magnetic resonance imaging (MRI)-defined apparent diffusion coefficient reduction (ADC-R) in a rat model of thromboembolic occlusion of the middle cerebral artery. Rats received either intracarotid recombinant tissue plasminogen activator (rt-PA) or saline. Microvascu...

journal_title：Neuroscience letters

authors： Vosko MR,Busch E,Burggraf D,Bültemeier G,Hamann GF

更新日期：2003-12-26 00:00:00

abstract：:Apolipoprotein E (ApoE) genotype was determined by polymerase chain reaction amplification and restriction digestion of DNA extracted from brain tissues of 26 patients with clinically diagnosed and pathologically verified lobar atrophy (LA) and from blood of a further 22 patients with clinical LA. Brain tissue from 50...

journal_title：Neuroscience letters

authors： Pickering-Brown SM,Siddons M,Mann DM,Owen F,Neary D,Snowden JS

更新日期：1995-03-31 00:00:00

abstract：:During and after degeneration of the optic nerve afferents in the rat suprachiasmatic nucleus (SCN) postsynaptic density (PD) material is added to existing symmetrical and asymmetrical appositions of non-optic synapses on optic target neurons. If the correlation between thickness of the postsynaptic density and excita...

journal_title：Neuroscience letters

authors： Güldner FH,Ingham CA

更新日期：1980-04-01 00:00:00

abstract：:Evidence from mammalian studies suggests that brain derived neurotrophic factor (BDNF) and its receptor, trk B, are upregulated in neuronal cell bodies after injury. Although fish possess neurotrophins and display rapid functional and morphological recovery after central nervous system (CNS) injury, to date few studie...

journal_title：Neuroscience letters

authors： Dalton VS,Roberts BL,Borich SM

更新日期：2009-09-25 00:00:00

abstract：:L-Glutamate binding to cockroach central nervous system (CNS) membranes is unaffected by freeze-drying and subsequent rehydration. The dissociation constant is similarly unaltered by irradiation at a dose of 3 Mrad which affects only the number of biologically active binding sites. A molecular weight estimate for this...

journal_title：Neuroscience letters

authors： Sepúlveda MI,Sattelle DB

更新日期：1989-05-22 00:00:00

abstract：:The medial prefrontal cortex (mPFC) is thought to exert inhibitory control over stress-induced activation of the amygdala and neurocognitive effects. As evidence to support this, we examined how exposure to either a brief or prolonged stress affected on amygdalar c-Fos levels and recognition memory of animals with mPF...

journal_title：Neuroscience letters

authors： Park JC,Jeon YJ,Kim JJ,Cho J,Choi DH,Han JS

更新日期：2020-09-14 00:00:00

abstract：:Serotonin type-3 (5-HT3) receptors are cation permeable membrane receptors which are involved in modulation of calcium entry in neuronal cells. Along with other ion-channels such as the N-methyl-D-aspartate receptor, it appears to be a target for the actions of ethanol and has been the focus of considerable work in th...

journal_title：Neuroscience letters

authors： Li X,DePetrillo PB

更新日期：2002-10-11 00:00:00