Xenogeneic dopaminergic grafts reverse behavioral deficits induced by 6-OHDA in rodents: effect of 15-deoxyspergualin treatment.

abstract：:CSF-A beta 42 may be a marker of Alzheimer's disease (AD). A decreased level of CSF-A beta 42 is consistently found in AD and has been suggested to be related to the deposition of amyloid plaques in the brain. However, low CSF-A beta 42 levels have also been found in disorders devoid of plaques, for instance Creutzfel...

journal_title：Neuroscience letters

authors： Sjögren M,Gisslén M,Vanmechelen E,Blennow K

更新日期：2001-11-13 00:00:00

abstract：:Nitric oxide (NO) from endothelial or neuronal NO synthases (eNOS or nNOS) may contribute both to the cerebrovascular responses to oxygen and potentially to the peroxynitrite-mediated toxic effects of hyperbaric oxygen (HBO(2)) on the central nervous system (CNS O(2) toxicity). In mice lacking eNOS or nNOS (-/-), regi...

journal_title：Neuroscience letters

authors： Demchenko IT,Atochin DN,Boso AE,Astern J,Huang PL,Piantadosi CA

更新日期：2003-06-19 00:00:00

abstract：:Global cerebral ischemia-reperfusion (GCI/R) may occur after any of several clinical conditions such as cardiac arrest and anesthetic accident. Some dopamine receptor agonists possess neuroprotective effects. However, some of them may produce side effects during treatment. Piribedil, which is a dopamine D2/D3 receptor...

journal_title：Neuroscience letters

authors： Wang W,Liu L,Chen C,Jiang P,Zhang T

更新日期：2018-09-25 00:00:00

abstract：:We investigated the cortico-muscular coherence in a patient with posturally induced cortically originating negative myoclonus. We recorded simultaneously 50 channels EEG and EMG from quadriceps and biceps femoris muscles of the left upper leg. Three experimental conditions were investigated with the patient in a seate...

journal_title：Neuroscience letters

authors： Kristeva R,Popa T,Chakarov V,Hummel S

更新日期：2004-08-19 00:00:00

abstract：:Online shopping festivals play a significant role in consumers' purchase decision and have been the focus of much research and many marketing practices. However, research has yet to explore which product categories can promote consumer purchase intention during online shopping festivals. This study carried out a neuro...

journal_title：Neuroscience letters

authors： Shang Q,Jin J,Qiu J

更新日期：2020-01-10 00:00:00

abstract：:By combining techniques designed to increase the amount of horseradish peroxidase (HRP) available for transport and to improve the sensitivity of the reaction for detecting HRP, we have produced an anterograde HRP technique suitable for labeling sparse efferent projections. The efficacy of this light, microscopic tech...

journal_title：Neuroscience letters

authors： West JR,Black AC Jr

更新日期：1979-04-01 00:00:00

abstract：:We examined the effects of ibotenic acid induced unilateral lesion of the nucleus basalis magnocellularis (nBM) on carbachol- and serotonin-stimulated phosphoinositide (PI) breakdown in miniprisms obtained from rat fronto-parietal cortex 1 week following the lesion. Lesion-side muscarinic and serotoninergic receptor r...

journal_title：Neuroscience letters

authors： Erfurth A,Holmes TC

更新日期：1995-06-23 00:00:00

abstract：:There is an emotional pressor circuit composed of nuclei controlling emotion and stress, which may be the neurophysiological basis for prolonged emotional stress inducing hypertension. The central amygdaloid nucleus (AC) is the most important in this circuit, which widely connects with the other nuclei via its CRF (co...

journal_title：Neuroscience letters

authors： Li YH,Ku YH

更新日期：2002-04-19 00:00:00

abstract：:We have examined the morphology and distribution of nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-diaphorase) cells in the retina of the guinea pig. Two morphologically distinct classes of labelled cells were detected, one with larger, darkly labelled somata commonly located in the inner nuclear layer ...

journal_title：Neuroscience letters

authors： Cobcroft M,Vaccaro T,Mitrofanis J

更新日期：1989-08-14 00:00:00

abstract：:Alzheimer' disease is a neurodegenerative disorder characterized by the misfolding and aggregation of amyloid β (Aβ). This process is influenced through supply of cholesterol via apolipoproteins to neurons. In the present study, we used the transgenic Caenorhabditis elegans strain CL2006, which expresses Aβ1-42 under ...

journal_title：Neuroscience letters

authors： Regitz C,Wenzel U

更新日期：2014-07-25 00:00:00

abstract：:In order to assess functional skills of older adults, both timed up and go (TUG) test and gait speed (GS) test are well validated concerning their predictive capacities. However, the question remains unclear which one of these tests represents better the whole physical performance of older adults. The aim of this stud...

journal_title：Neuroscience letters

authors： Kubicki A

更新日期：2014-08-08 00:00:00

abstract：:In anesthetized rats, injections of a 0.5 mM glutamate solution into the locus coeruleus (LC) reversibly increased the amplitude of the population spike evoked in CA1 by stimulation of the Schaffer-commissural fiber tract. This effect was absent in N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine (DSP-4)-treated, noradren...

journal_title：Neuroscience letters

authors： Olpe HR,Laszlo J,Pozza MF,De Herdt P,Waldmeier PC,Jones RS

更新日期：1986-03-28 00:00:00

abstract：:Prior motor skill learning (original learning; OL) with one hand (original hand; OH) can affect relearning of the same skill (transfer learning; TL) with the opposite hand (transferred hand; TH). This phenomenon is known as intermanual transfer of learning. We explored specialization of brain activation underlying too...

journal_title：Neuroscience letters

authors： Obayashi S,Suhara T,Kawabe K,Okauchi T,Maeda J,Nagai Y,Iriki A

更新日期：2003-03-20 00:00:00

abstract：:We measured levels of basal and norepinephrine (NE) -induced melatonin release in cultured pineal bodies of rats just after and 2 days after irradiation (20 or 200 Gy) or sham-irradiation. On the day of irradiation, basal and NE-induced melatonin release were not affected by irradiation. Two days after irradiation, ba...

journal_title：Neuroscience letters

authors： Saito K,Shinohara K,Morofushi M,Funabashi T,Mitsushima D,Hata M,Matsubara S,Kimura F

更新日期：2000-04-21 00:00:00

abstract：:Cholecystokinin (CCK) is suggested to be involved, e.g. in the central nervous modulation of food intake, possibly by acting within specific hypothalamic nuclei. Perinatal overnutrition predisposes to permanent obesity and hyperphagia, while underlying mechanisms are unclear. By reducing the litter size from the 3rd t...

journal_title：Neuroscience letters

authors： Plagemann A,Rake A,Harder T,Melchior K,Rohde W,Dörner G

更新日期：1998-12-11 00:00:00

abstract：:Increasing evidence shows that inflammation may contribute to the pathophysiology of depression. Apigenin, one type of natural flavone, has a number of biological actions including anti-inflammatory effects. Although it has potential antidepressant activity in a chronic mild stress model, the mechanisms of antidepress...

journal_title：Neuroscience letters

authors： Li R,Zhao D,Qu R,Fu Q,Ma S

更新日期：2015-05-06 00:00:00

abstract：:Using the dipole-tracing method, the source generators of N18, P22 and P40 of the somatosensory evoked potential (SEP) were estimated as the equivalent dipole. After voluntary action of the thumb flexion, no changes were observed in N18 or P40, but the amplitude of P22 was suppressed. The after-effects of intention ac...

journal_title：Neuroscience letters

authors： Homma S,Nakajima Y,Musha T,He B,Okamoto Y

更新日期：1988-06-07 00:00:00

abstract：:Parkinson's disease (PD) is a progressive age-related debilitating motor disorder and the second most common neurodegenerative disease after Alzheimer's disease. In this study, we aimed to investigate the expression of 24 candidate miRNAs in PD and to assess their diagnostic value in patients with PD. We collected ser...

journal_title：Neuroscience letters

authors： Cao XY,Lu JM,Zhao ZQ,Li MC,Lu T,An XS,Xue LJ

更新日期：2017-03-22 00:00:00

abstract：:Glycinergic inhibitory neurotransmission plays a pivotal role in the development of neuropathic pain. The glycine concentration in the synaptic cleft is controlled by the glycine transporters GlyT1 and GlyT2. GlyT1 is expressed throughout the central nervous system, while GlyT2 is exclusively located in glycinergic ne...

journal_title：Neuroscience letters

authors： Schlösser L,Barthel F,Brandenburger T,Neumann E,Bauer I,Eulenburg V,Werdehausen R,Hermanns H

更新日期：2015-07-23 00:00:00

abstract：:In non-diabetic mice, s.c. injection of formalin to the hindpaw had a biphasic effect: an immediate nociceptive response (first-phase) followed by a tonic response (second-phase). However, only the immediate nociceptive response was observed in diabetic mice. The duration of the first-phase response was significantly ...

journal_title：Neuroscience letters

authors： Kamei J,Hitosugi H,Kasuya Y

更新日期：1993-01-12 00:00:00

abstract：:Exposure to negative environmental events triggers defensive behavior and leads to the formation of aversive associative memory. Cellular and molecular changes in the central nervous system underlie this memory formation, as well as the associated behavioral changes. In general, memory process is established in distin...

journal_title：Neuroscience letters

authors： Faria RS,Gutierres LF,Sobrinho FC,Miranda Ido V,Reis JD,Dias EV,Sartori CR,Moreira DA

更新日期：2016-08-15 00:00:00

abstract：:A paired-pulse stimulus protocol was used to measure angular bundle to dentate gyrus paired-pulse inhibition in rats before and after the occurrence of 36 or 72 seizures elicited from the contralateral CA3 region. The seizures showed progressive lengthening. There was a moderate increase in paired-pulse depression 1 h...

journal_title：Neuroscience letters

authors： Stringer JL,Lothman EW

更新日期：1989-10-23 00:00:00

abstract：:Immediate post-training intraperitoneal administration of the centrally acting anticholinesterase physostigmine (70.0, or 150.0 microg/kg) enhanced retention of male CF-1 mice tested 48 h after training in a one-trial step-through inhibitory avoidance task (0.8 mA, 50 Hz, 1 s footshock). The effect was observed in mic...

journal_title：Neuroscience letters

authors： Boccia MM,Blake MG,Acosta GB,Baratti CM

更新日期：2003-07-17 00:00:00

abstract：:There is evidence to support that oxidative stress is increased in Parkinson's disease (PD) and contributes to the degeneration of dopaminergic neurons. Recent research has shown that higher blood urate concentrations have now been linked to decreased risks and progression rates of PD. However, the mechanisms about ur...

journal_title：Neuroscience letters

authors： Zhu TG,Wang XX,Luo WF,Zhang QL,Huang TT,Xu XS,Liu CF

更新日期：2012-01-11 00:00:00

abstract：:The effect of methionine-enkephalin (Met-Enk) on responses of rat brain neostriatum neurones to microiontophoretic application of glutamate was studied in experiments with extracellular recording of spike activity. Met-Enk administered by microiontophoresis was shown to depress the glutamate-induced responses. In para...

journal_title：Neuroscience letters

authors： Kuznetsov VI,Godukhin OV

更新日期：1985-06-12 00:00:00

abstract：:We examined the association between endogenous opioid β-endorphin, cancer progression and pain in a transgenic mouse model of breast cancer, with a rat C3(1) simian virus 40 large tumor antigen fusion gene (C3TAg). C3TAg mice develop ductal epithelial atypia at 8 weeks, progression to intra-epithelial neoplasia at 12 ...

journal_title：Neuroscience letters

authors： Argueta DA,Aich A,Lei J,Kiven S,Nguyen A,Wang Y,Gu J,Zhao W,Gupta K

更新日期：2021-01-23 00:00:00

abstract：:Whole-cell patch-clamp recordings were made from kidney-related neurons in the intermediolateral cell column (IML) in horizontal slices of thoracolumbar spinal cord from adult rats. Kidney-related neurons were identified in vitro subsequent to inoculation of the kidney with a fluorescent, retrograde, transynaptic pseu...

journal_title：Neuroscience letters

authors： Derbenev AV,Duale H,Rabchevsky AG,Smith BN

更新日期：2010-05-03 00:00:00

abstract：:The intracellular stress-induced proteins provide protection against toxic insults. Here, a 60,000-Da heat shock 60 (hsp60)-like protein was detected, with five different antibodies, in conditioned media derived from rat cortical astrocytes and a human neuroblastoma cell line. Extracellular neuroblastoma hsp60-like im...

journal_title：Neuroscience letters

authors： Bassan M,Zamostiano R,Giladi E,Davidson A,Wollman Y,Pitman J,Hauser J,Brenneman DE,Gozes I

更新日期：1998-06-26 00:00:00

abstract：:Cytoplasmic acidification in taste receptor cells is thought to be involved, at least in part, in acid taste transduction. Since in taste buds about 20% of the receptor cells are electrically coupled, we have tested whether reduction in intracellular pH affects these lateral synaptic interactions. By applying the patc...

journal_title：Neuroscience letters

authors： Bigiani A,Roper SD

更新日期：1994-08-01 00:00:00

abstract：:By means of a new photographic method to quantitate catecholamine fluorescence in tissue sections it has been possible to demonstrate a high dopamine (DA) turnover within the DA cell bodies of the midbrain. The medially located small-sized DA cell bodies of the A10 DA cell group has a very high DA turnover which was s...

journal_title：Neuroscience letters

authors： Agnati LF,Fuxe K,Andersson K,Benfenati F,Cortelli P,D'Alessandro R

更新日期：1980-05-15 00:00:00